产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody - ChIP Grade
目录 :
ab5131
规格 :
25微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, , 非洲爪蛙, 拟南芥
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, ChIP-Seq
文章摘录数: 69
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 图 3a
Rezazadeh S, Yang D, Biashad S, Firsanov D, Takasugi M, Gilbert M, et al. SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. Aging (Albany NY). 2020;12:11165-11184 pubmed 出版商
  • ChIP-Seq; 人类; 图 4c
  • 染色质免疫沉淀 ; 人类; 图 s5b, f, 4c
Senigl F, Maman Y, Dinesh R, Alinikula J, Seth R, Pecnova L, et al. Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation. Cell Rep. 2019;29:3902-3915.e8 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s3i
Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, et al. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019;5:eaaw3593 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 2g
Lee J, Yesilkanal A, Wynne J, Frankenberger C, Liu J, Yan J, et al. Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019;568:254-258 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Yu F, Shi G, Cheng S, Chen J, Wu S, Wang Z, et al. SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Res. 2018;28:670-685 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6h
Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 7a
Czimmerer Z, Dániel B, Horvath A, Rückerl D, Nagy G, Kiss M, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018;48:75-90.e6 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 1k, 2b, 2c, 2e, 2g
de Morrée A, van Velthoven C, Gan Q, Salvi J, Klein J, Akimenko I, et al. Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence. Proc Natl Acad Sci U S A. 2017;114:E8996-E9005 pubmed 出版商
  • ChIP-Seq; 小鼠; 表 1
Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠; 图 4
Soboleva T, Parker B, Nekrasov M, Hart Smith G, Tay Y, Tng W, et al. A new link between transcriptional initiation and pre-mRNA splicing: The RNA binding histone variant H2A.B. PLoS Genet. 2017;13:e1006633 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 4f
Mathew R, Tatarakis A, Rudenko A, Johnson Venkatesh E, Yang Y, Murphy E, et al. A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory. elife. 2016;5: pubmed 出版商
  • 免疫组化; 人类; 图 2a
Hill S, Mordes D, Cameron L, Neuberg D, Landini S, Eggan K, et al. Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. Proc Natl Acad Sci U S A. 2016;113:E7701-E7709 pubmed
  • 免疫印迹; 人类; 1:500; 图 5c
Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed 出版商
  • 免疫细胞化学; 仓鼠; 图 s8a
Tajik A, Zhang Y, Wei F, Sun J, Jia Q, Zhou W, et al. Transcription upregulation via force-induced direct stretching of chromatin. Nat Mater. 2016;15:1287-1296 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 2a
Zhang X, Wu J, Wang J, Shen T, Li H, Lu J, et al. Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cells. Genome Biol. 2016;17:162 pubmed 出版商
  • 免疫沉淀; 小鼠; 2 ug/ml; 图 4
Chung H, Xu C, Fuchs A, Mund A, Lange M, Staege H, et al. PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. elife. 2016;5: pubmed 出版商
  • 染色质免疫沉淀 ; 拟南芥; 图 4
Liu N, Avramova Z. Molecular mechanism of the priming by jasmonic acid of specific dehydration stress response genes in Arabidopsis. Epigenetics Chromatin. 2016;9:8 pubmed 出版商
  • ChIP-Seq; 鸡; 图 5
Williams A, Maman Y, Alinikula J, Schatz D. Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells. PLoS ONE. 2016;11:e0149146 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Boulding T, Wu F, McCuaig R, Dunn J, Sutton C, Hardy K, et al. Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer. PLoS ONE. 2016;11:e0148065 pubmed 出版商
  • 染色质免疫沉淀 ; 非洲爪蛙; 图 4
Tamaoki K, Okada R, Ishihara A, Shiojiri N, Mochizuki K, Goda T, et al. Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis. Cell Biosci. 2016;6:2 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 5d
Liu G, Zhao G, Chen X, Hao D, Zhao X, Lv X, et al. The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster. Nucleic Acids Res. 2016;44:2613-27 pubmed 出版商
Maury E, Navez B, Brichard S. Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation. Nat Commun. 2021;12:2388 pubmed 出版商
Zhang M, Lai Y, Krupalnik V, Guo P, Guo X, Zhou J, et al. β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus. Sci Adv. 2020;6:eaba1593 pubmed 出版商
Kato S, Weng Q, Insco M, Chen K, Muralidhar S, Poźniak J, et al. Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis. Cancer Discov. 2020;10:980-997 pubmed 出版商
Weiterer S, Meier Soelch J, Georgomanolis T, Mizi A, Beyerlein A, Weiser H, et al. Distinct IL-1α-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner. EMBO J. 2019;:e101533 pubmed 出版商
Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed 出版商
Pacini V, Petit F, Querat B, Laverrière J, Cohen Tannoudji J, L hôte D. Identification of a pituitary ERα-activated enhancer triggering the expression of Nr5a1, the earliest gonadotrope lineage-specific transcription factor. Epigenetics Chromatin. 2019;12:48 pubmed 出版商
Wu S, Naar A. SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Sci Rep. 2019;9:10369 pubmed 出版商
Rezazadeh S, Yang D, Tombline G, Simon M, Regan S, Seluanov A, et al. SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170. Nucleic Acids Res. 2019;: pubmed 出版商
Chan S, Tang Y, Miao L, Darwich Codore H, Vejnar C, Beaudoin J, et al. Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation. Dev Cell. 2019;49:867-881.e8 pubmed 出版商
Albert B, Kos Braun I, Henras A, Dez C, Rueda M, Zhang X, et al. A ribosome assembly stress response regulates transcription to maintain proteome homeostasis. elife. 2019;8: pubmed 出版商
Miao H, Wang L, Zhan H, Dai J, Chang Y, Wu F, et al. A long noncoding RNA distributed in both nucleus and cytoplasm operates in the PYCARD-regulated apoptosis by coordinating the epigenetic and translational regulation. PLoS Genet. 2019;15:e1008144 pubmed 出版商
Dong Z, Zhong X, Lei Q, Chen F, Cui H. Transcriptional activation of SIRT6 via FKHRL1/FOXO3a inhibits the Warburg effect in glioblastoma cells. Cell Signal. 2019;60:100-113 pubmed 出版商
Nagashima R, Hibino K, Ashwin S, Babokhov M, Fujishiro S, Imai R, et al. Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II. J Cell Biol. 2019;218:1511-1530 pubmed 出版商
Munro N, Srinageshwar B, Shalabi F, Florendo M, Otero P, Thompson C, et al. A novel approach to label bone marrow-derived mesenchymal stem cells with mixed-surface PAMAM dendrimers. Stem Cell Res Ther. 2019;10:71 pubmed 出版商
Gallego Bartolome J, Liu W, Kuo P, Feng S, Ghoshal B, Gardiner J, et al. Co-targeting RNA Polymerases IV and V Promotes Efficient De Novo DNA Methylation in Arabidopsis. Cell. 2019;176:1068-1082.e19 pubmed 出版商
Damodaran K, Venkatachalapathy S, Alisafaei F, Radhakrishnan A, Sharma Jokhun D, Shenoy V, et al. Compressive force induces reversible chromatin condensation and cell geometry dependent transcriptional response. Mol Biol Cell. 2018;:mbcE18040256 pubmed 出版商
Ng Y, Chung W, Kang H, Cho H, Park E, Kang S, et al. A DNA-sensing-independent role of a nuclear RNA helicase, DHX9, in stimulation of NF-κB-mediated innate immunity against DNA virus infection. Nucleic Acids Res. 2018;46:9011-9026 pubmed 出版商
Wu D, De Wever V, Derua R, Winkler C, Beullens M, Van Eynde A, et al. A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions. J Biol Chem. 2018;293:15152-15162 pubmed 出版商
Bruzzone M, Grünberg S, Kubik S, Zentner G, Shore D. Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genes. Genes Dev. 2018;32:1252-1265 pubmed 出版商
Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, et al. Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proc Natl Acad Sci U S A. 2018;115:E7795-E7804 pubmed 出版商
Cichocki F, Wu C, Zhang B, Felices M, Tesi B, Tuininga K, et al. ARID5B regulates metabolic programming in human adaptive NK cells. J Exp Med. 2018;215:2379-2395 pubmed 出版商
Meier Soelch J, Jurida L, Weber A, Newel D, Kim J, Braun T, et al. RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target Genes. Front Immunol. 2018;9:775 pubmed 出版商
Parikh R, Lin H, Gangaraju V. A critical role for nucleoporin 358 (Nup358) in transposon silencing and piRNA biogenesis in Drosophila. J Biol Chem. 2018;293:9140-9147 pubmed 出版商
Cho S, Xu J, Sun R, Mumbach M, Carter A, Chen Y, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. 2018;173:1398-1412.e22 pubmed 出版商
Cook A, Hari Gupta Y, Toseland C. Application of the SSB biosensor to study in vitro transcription. Biochem Biophys Res Commun. 2018;496:820-825 pubmed 出版商
Michelini F, Pitchiaya S, Vitelli V, Sharma S, Gioia U, Pessina F, et al. Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks. Nat Cell Biol. 2017;19:1400-1411 pubmed 出版商
Dimitrov V, Bouttier M, Boukhaled G, Salehi Tabar R, Avramescu R, Memari B, et al. Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice. J Biol Chem. 2017;292:20657-20668 pubmed 出版商
Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald K. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. J Immunol. 2017;199:3249-3260 pubmed 出版商
Wang Y, Nagarajan M, Uhler C, Shivashankar G. Orientation and repositioning of chromosomes correlate with cell geometry-dependent gene expression. Mol Biol Cell. 2017;28:1997-2009 pubmed 出版商
Lee Y, Park D, Iyer V. The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes. Nucleic Acids Res. 2017;45:7180-7190 pubmed 出版商
He R, Kidder B. H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells. Nucleic Acids Res. 2017;45:6427-6441 pubmed 出版商
Mueller B, Mieczkowski J, Kundu S, Wang P, Sadreyev R, Tolstorukov M, et al. Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction. Genes Dev. 2017;31:451-462 pubmed 出版商
Wang Y, Ratna P, Shivashankar G. Superresolution imaging of nanoscale chromosome contacts. Sci Rep. 2017;7:42422 pubmed 出版商
Alvarez Carbonell D, Garcia Mesa Y, Milne S, Das B, Dobrowolski C, Rojas R, et al. Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells. Retrovirology. 2017;14:9 pubmed 出版商
Borsos B, Huliák I, Majoros H, Ujfaludi Z, Gyenis A, Pukler P, et al. Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage. Sci Rep. 2017;7:40960 pubmed 出版商
Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, et al. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Res. 2017;45:3738-3751 pubmed 出版商
Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed 出版商
Deshmukh A, Mitra P, Maruthi M. Cdk7 mediates RPB1-driven mRNA synthesis in Toxoplasma gondii. Sci Rep. 2016;6:35288 pubmed 出版商
Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto A, Yang Y, Ntziachristos P, et al. Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nat Cell Biol. 2016;18:1127-1138 pubmed 出版商
Nakazawa N, Sathe A, Shivashankar G, Sheetz M. Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression. Proc Natl Acad Sci U S A. 2016;113:E6813-E6822 pubmed
Ishiguro K, Monti M, Akiyama T, Kimura H, Chikazawa Nohtomi N, Sakota M, et al. Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis. In Vitro Cell Dev Biol Anim. 2017;53:167-178 pubmed 出版商
Shih H, Chen W, Liu K, Shih Z, Chen Y, Hsieh P, et al. dBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations. PLoS Genet. 2016;12:e1006262 pubmed 出版商
Navarro Costa P, McCarthy A, Prudêncio P, Greer C, Guilgur L, Becker J, et al. Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling. Nat Commun. 2016;7:12331 pubmed 出版商
Heinaniemi M, Vuorenmaa T, Teppo S, Kaikkonen M, Bouvy Liivrand M, Mehtonen J, et al. Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots. elife. 2016;5: pubmed 出版商
Hori T, Moore R, Negishi M. p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38. Drug Metab Dispos. 2016;44:871-6 pubmed 出版商
Portnoy V, Lin S, Li K, Burlingame A, Hu Z, Li H, et al. saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription. Cell Res. 2016;26:320-35 pubmed 出版商
Saintamand A, Vincent Fabert C, Garot A, Rouaud P, Oruc Z, Magnone V, et al. Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region. Nat Commun. 2016;7:10730 pubmed 出版商
Chou C, Pinto A, Curtis J, Persaud S, Cella M, Lin C, et al. c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells. Nat Immunol. 2014;15:884-93 pubmed 出版商
产品信息
目录号 :
ab5131
ItemName :
Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody - ChIP Grade
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
磷酸化(5S)
规格 :
25微克
物种摘要 :
At, Ce, Dm, Hu, Ms, Rat, S pom, Sc, Xl, Zfsh
用途 :
ChIP, CHIPseq, ELISA, ICC/IF, IHC - Wmt, IHC-Fr, IHC-P, IP, WB
规格说明 :
Other sizes available: 50 µg,100 µl,200 µl,300 µl,1000 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。