产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗低密度脂蛋白受体抗体[EP1553Y]
目录 :
ab52818
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP1553Y
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证, 免疫组化基因敲除验证
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed 出版商
  • 免疫印迹; 人类; 1.4 ug/ml; 图 1d
  • 免疫印迹; 小鼠; 1.4 ug/ml; 图 1e
Muramatsu M, Osawa T, Miyamura Y, Nakagawa S, Tanaka T, Kodama T, et al. Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background. J Biol Chem. 2021;296:100697 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:2000; 图 4b
Emmer B, Sherman E, Lascuna P, Graham S, Willer C, Ginsburg D. Genome-scale CRISPR screening for modifiers of cellular LDL uptake. PLoS Genet. 2021;17:e1009285 pubmed 出版商
  • 免疫印迹; 人类; 1:250; 图 5g
Aregger M, Lawson K, Billmann M, Costanzo M, Tong A, Chan K, et al. Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism. Nat Metab. 2020;2:499-513 pubmed 出版商
  • 免疫印迹; 人类; 图 4g
Jiang Y, Sun A, Zhao Y, Ying W, Sun H, Yang X, et al. Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma. Nature. 2019;567:257-261 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 e4e
  • 免疫印迹; 人类; 图 3d, e5d
Garcia Bermudez J, Baudrier L, Bayraktar E, Shen Y, La K, Guarecuco R, et al. Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Nature. 2019;567:118-122 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Zhu L, Shi J, Luu T, Neuman J, Trefts E, Yu S, et al. Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding. Mol Metab. 2018;8:106-116 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s5d
Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 4d
  • 免疫印迹; 人类; 图 4c
Gallagher E, Zelenko Z, Neel B, Antoniou I, Rajan L, Kase N, et al. Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia. Oncogene. 2017;36:6462-6471 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Zhao D, Lizardo K, Cui M, Ambadipudi K, Lora J, Jelicks L, et al. Antagonistic effect of atorvastatin on high fat diet induced survival during acute Chagas disease. Microbes Infect. 2016;18:675-686 pubmed 出版商
  • 免疫组化基因敲除验证; 小鼠; 1:1000; 图 4
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 2
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 6
Tao W, Moore R, Meng Y, Smith E, Xu X. Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol. J Lipid Res. 2016;57:809-17 pubmed 出版商
  • 免疫印迹; 人类; 图 3
De Gonzalo Calvo D, López Vilaró L, Nasarre L, Pérez Olabarría M, Vázquez T, Escuin D, et al. Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study. BMC Cancer. 2015;15:460 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7B
Zhong C, Sun W, Ma Y, Zhu H, Yang P, Wei H, et al. Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice. Sci Rep. 2015;5:10512 pubmed 出版商
  • 免疫印迹; 人类
Stöhr R, Mavilio M, Marino A, Casagrande V, Kappel B, Möllmann J, et al. ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice. Sci Rep. 2015;5:9023 pubmed 出版商
Tao L, Tian S, Zhang J, Liu Z, Robinson McCarthy L, Miyashita S, et al. Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells. Nat Microbiol. 2019;: pubmed 出版商
Leitch E, Elumalai N, Fridén Saxin M, Dahl G, Wan P, Clarkson P, et al. Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase. Chem Sci. 2018;9:5957-5966 pubmed 出版商
Thakore P, Kwon J, Nelson C, Rouse D, Gemberling M, Oliver M, et al. RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. Nat Commun. 2018;9:1674 pubmed 出版商
Yang S, Xu R, Cui C, Wang Y, Du Y, Chen Z, et al. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovasc Diabetol. 2018;17:48 pubmed 出版商
Cook E, Nelson J, Sorrentino V, Koenis D, Moeton M, Scheij S, et al. Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene. PLoS ONE. 2017;12:e0172721 pubmed 出版商
Jensen K, Tadin Strapps M, Wang S, Hubert J, Kan Y, Ma Y, et al. Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey. J Lipid Res. 2016;57:2150-2162 pubmed
Nagajyothi F, Weiss L, Zhao D, Koba W, Jelicks L, Cui M, et al. High fat diet modulates Trypanosoma cruzi infection associated myocarditis. PLoS Negl Trop Dis. 2014;8:e3118 pubmed 出版商
Pedrelli M, Davoodpour P, Degirolamo C, Gomaraschi M, Graham M, Ossoli A, et al. Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice. PLoS ONE. 2014;9:e93552 pubmed 出版商
Nagajyothi F, Weiss L, Silver D, Desruisseaux M, Scherer P, Herz J, et al. Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. PLoS Negl Trop Dis. 2011;5:e953 pubmed 出版商
Thysell E, Surowiec I, Hörnberg E, Crnalic S, Widmark A, Johansson A, et al. Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol. PLoS ONE. 2010;5:e14175 pubmed 出版商
产品信息
目录号 :
ab52818
ItemName :
抗低密度脂蛋白受体抗体[EP1553Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP1553Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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