产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗表皮生长因子受体抗体[EP38Y]
目录 :
ab52894
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP38Y
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, mass cytometry, 免疫组化基因敲除验证
文章摘录数: 47
出版应用/物种/样本/稀释参考文献
  • 免疫组化基因敲除验证; 小鼠; 图 9b
Wen H, Gao S, Wang Y, Ray M, Magnuson M, Wright C, et al. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed 出版商
  • mass cytometry; 人类; 图 3a
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 s5
Pergu R, Dagar S, Kumar H, Kumar R, Bhattacharya J, Mylavarapu S. The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. J Biol Chem. 2019;294:7177-7193 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Liang C, Ma Y, Yong L, Yang C, Wang P, Liu X, et al. Y-box binding protein-1 promotes tumorigenesis and progression via the epidermal growth factor receptor/AKT pathway in spinal chordoma. Cancer Sci. 2019;110:166-179 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1a
  • 免疫印迹; 人类; 图 1c
Lee S, Cho Y, Cha P, Yoon J, Ro E, Jeong W, et al. A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab. Exp Mol Med. 2018;50:153 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500
  • 免疫组化-石蜡切片; 人类; 1:500
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
  • 免疫细胞化学; 人类; 1:960; 图 s8
Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Ma K, Fu W, Tang M, Zhang C, Hou T, Li R, et al. PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment. Autophagy. 2017;13:579-591 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 4a
  • 免疫印迹; 人类; 图 4d
Zhang Y, Yang J, Ding M, Li L, Lu Z, Zhang Q, et al. Tumor-penetration and antitumor efficacy of cetuximab are enhanced by co-administered iRGD in a murine model of human NSCLC. Oncol Lett. 2016;12:3241-3249 pubmed
  • 免疫印迹; 人类; 1:1000; 图 8
Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm Helm A, Noortoots A, et al. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J Cell Sci. 2016;129:3792-3802 pubmed
  • 免疫细胞化学; 小鼠; 图 s1
  • 免疫组化; 小鼠; 图 1
Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7c
He F, Wei L, Luo W, Liao Z, Li B, Zhou X, et al. Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. Oncotarget. 2016;7:37000-37012 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Derangère V, Fumet J, Boidot R, Bengrine L, Limagne E, Chevriaux A, et al. Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?. Oncotarget. 2016;7:9309-21 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 3a
Hessmann E, Zhang J, Chen N, Hasselluhn M, Liou G, Storz P, et al. NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation. Stem Cells Int. 2016;2016:5272498 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Mehner C, Oberg A, Kalli K, Nassar A, Hockla A, Pendlebury D, et al. Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers. Oncotarget. 2015;6:35737-54 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s8
Fu Y, Cruz Monserrate Z, Helen Lin H, Chung Y, Ji B, Lin S, et al. Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype. Sci Rep. 2015;5:13347 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
  • 免疫印迹; 小鼠; 1:1000
Tang Y, Ye M, Du Y, Qiu X, Lv X, Yang W, et al. EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus. Neuroscience. 2015;304:109-21 pubmed 出版商
  • 免疫印迹; 小鼠
Chen C, Kim K, Lau L. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene. 2016;35:1314-23 pubmed 出版商
  • 免疫组化; 人类
Restivo G, Nguyen B, Dziunycz P, Ristorcelli E, Ryan R, Özuysal Ö, et al. IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011;30:4571-85 pubmed 出版商
Du F, Qiao C, Li X, Chen Z, Liu H, Wu S, et al. Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR. Theranostics. 2019;9:3879-3902 pubmed 出版商
Stringer B, Day B, D Souza R, Jamieson P, Ensbey K, Bruce Z, et al. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma. Sci Rep. 2019;9:4902 pubmed 出版商
RAMIREZ A, Bhat R, Sahay D, De Angelis C, Thangavel H, Hedayatpour S, et al. Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis. BMC Cancer. 2019;19:220 pubmed 出版商
Gao Q, Yang Z, Xu S, Li X, Yang X, Jin P, et al. Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer. J Exp Med. 2019;216:688-703 pubmed 出版商
Zhu T, An S, Choy M, Zhou J, Wu S, Liu S, et al. LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression. J Cell Mol Med. 2018;: pubmed 出版商
Zhang M, Zhao K, Xu X, Yang Y, Yan S, Wei P, et al. A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma. Nat Commun. 2018;9:4475 pubmed 出版商
Liu F, Shangli Z, Hu Z. CAV2 promotes the growth of renal cell carcinoma through the EGFR/PI3K/Akt pathway. Onco Targets Ther. 2018;11:6209-6216 pubmed 出版商
Cunha L, Yang M, Carter R, Guy C, Harris L, Crawford J, et al. LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance. Cell. 2018;175:429-441.e16 pubmed 出版商
Mao J, Ma L, Shen Y, Zhu K, Zhang R, Xi W, et al. Arsenic circumvents the gefitinib resistance by binding to P62 and mediating autophagic degradation of EGFR in non-small cell lung cancer. Cell Death Dis. 2018;9:963 pubmed 出版商
Fu H, Zhang W, Yuan Q, Niu M, Zhou F, Qiu Q, et al. PAK1 Promotes the Proliferation and Inhibits Apoptosis of Human Spermatogonial Stem Cells via PDK1/KDR/ZNF367 and ERK1/2 and AKT Pathways. Mol Ther Nucleic Acids. 2018;12:769-786 pubmed 出版商
Chu H, Chan C, Zhang X, Wang Y, Yuan S, Zhou J, et al. Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem. 2018;293:11709-11726 pubmed 出版商
Bombardo M, Saponara E, Malagola E, Chen R, Seleznik G, Haumaitre C, et al. Class I histone deacetylase inhibition improves pancreatitis outcome by limiting leukocyte recruitment and acinar-to-ductal metaplasia. Br J Pharmacol. 2017;174:3865-3880 pubmed 出版商
Li S, Zhou J, Bu J, Ning K, Zhang L, Li J, et al. Ectodysplasin A protein promotes corneal epithelial cell proliferation. J Biol Chem. 2017;292:13391-13401 pubmed 出版商
Tripathi S, Fahrmann J, Celiktaş M, Aguilar M, Marini K, Jolly M, et al. MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway. Cancer Res. 2017;77:4414-4425 pubmed 出版商
Modica G, Skorobogata O, Sauvageau E, Vissa A, Yip C, Kim P, et al. Rab7 palmitoylation is required for efficient endosome-to-TGN trafficking. J Cell Sci. 2017;130:2579-2590 pubmed 出版商
Williams V, Grosset A, Zamorano Cuervo N, St Pierre Y, Sylvestre M, Gaboury L, et al. Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis. BMC Cancer. 2017;17:356 pubmed 出版商
Liang J, Zheng S, Xiao X, Wei J, Zhang Z, Ernberg I, et al. Epstein-Barr virus-encoded LMP2A stimulates migration of nasopharyngeal carcinoma cells via the EGFR/Ca2+/calpain/ITG?4 axis. Biol Open. 2017;6:914-922 pubmed 出版商
Samkoe K, Tichauer K, Gunn J, Wells W, Hasan T, Pogue B. Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach. Cancer Res. 2014;74:7465-74 pubmed 出版商
Brand T, Iida M, Dunn E, Luthar N, Kostopoulos K, Corrigan K, et al. Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer. Mol Cancer Ther. 2014;13:1356-68 pubmed 出版商
Iida M, Brand T, Starr M, Li C, Huppert E, Luthar N, et al. Sym004, a novel EGFR antibody mixture, can overcome acquired resistance to cetuximab. Neoplasia. 2013;15:1196-206 pubmed
Brand T, Iida M, Luthar N, Wleklinski M, Starr M, Wheeler D. Mapping C-terminal transactivation domains of the nuclear HER family receptor tyrosine kinase HER3. PLoS ONE. 2013;8:e71518 pubmed 出版商
Kalinowski F, Giles K, Candy P, Ali A, Ganda C, Epis M, et al. Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7. PLoS ONE. 2012;7:e47067 pubmed 出版商
Clark P, Iida M, Treisman D, Kalluri H, Ezhilan S, Zorniak M, et al. Activation of multiple ERBB family receptors mediates glioblastoma cancer stem-like cell resistance to EGFR-targeted inhibition. Neoplasia. 2012;14:420-8 pubmed
Choi K, Chang K, Pickel J, Badger J, Roche K. Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice. Proc Natl Acad Sci U S A. 2011;108:15219-24 pubmed 出版商
Bade L, Goldberg J, Dehut H, Hall M, Schwertfeger K. Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor. J Cell Sci. 2011;124:3106-17 pubmed 出版商
Raina D, Kosugi M, Ahmad R, Panchamoorthy G, Rajabi H, Alam M, et al. Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells. Mol Cancer Ther. 2011;10:806-16 pubmed 出版商
Burga L, Hu H, Juvekar A, Tung N, Troyan S, Hofstatter E, et al. Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Res. 2011;13:R30 pubmed 出版商
Giles K, Barker A, Zhang P, Epis M, Leedman P. MicroRNA regulation of growth factor receptor signaling in human cancer cells. Methods Mol Biol. 2011;676:147-63 pubmed 出版商
产品信息
目录号 :
ab52894
ItemName :
抗表皮生长因子受体抗体[EP38Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP38Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。