产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗拓扑异构酶II甲抗体[EP1102Y]
目录 :
ab52934
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP1102Y
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 5d
Lei X, Cao K, Chen Y, Shen H, Liu Z, Qin H, et al. Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells. J Exp Clin Cancer Res. 2021;40:224 pubmed 出版商
  • ChIP-Seq; 小鼠; ; 图 4a
Alvarez Quilón A, Terron Bautista J, Delgado Sainz I, Serrano Benítez A, Romero Granados R, Martínez García P, et al. Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency. Nat Commun. 2020;11:910 pubmed 出版商
  • 免疫印迹; 人类; 图 s10c
Senturk J, Bohlman S, Manfredi J. Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53. Oncogene. 2017;36:6085-6096 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 7d
  • 免疫印迹; 小鼠; 1:3000; 图 6a
  • 免疫印迹; 人类; 1:3000; 图 6b
Guturi K, Bohgaki M, Bohgaki T, Srikumar T, Ng D, Kumareswaran R, et al. RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation. Nat Commun. 2016;7:12638 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 8c
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 8a
Stefansdottir A, Johnston Z, Powles Glover N, Anderson R, Adams I, Spears N. Etoposide damages female germ cells in the developing ovary. BMC Cancer. 2016;16:482 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 1b
  • 免疫印迹; 小鼠; 图 1e
Jacobsen R, Mazloumi Gavgani F, Mellgren G, Lewis A. DNA Topoisomerase II? contributes to the early steps of adipogenesis in 3T3-L1 cells. Cell Signal. 2016;28:1593-603 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
d Alcontres M, Palacios J, Mejias D, Blasco M. TopoII? prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres. Cell Cycle. 2014;13:1463-81 pubmed 出版商
Gu N, Wang X, DI Z, Xiong J, Ma Y, Yan Y, et al. Silencing lncRNA FOXD2-AS1 inhibits proliferation, migration, invasion and drug resistance of drug-resistant glioma cells and promotes their apoptosis via microRNA-98-5p/CPEB4 axis. Aging (Albany NY). 2019;11:10266-10283 pubmed 出版商
Zeng S, Liu A, Dai L, Yu X, Zhang Z, Xiong Q, et al. Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms. BMC Cancer. 2019;19:604 pubmed 出版商
Canela A, Maman Y, Jung S, Wong N, Callen E, Day A, et al. Genome Organization Drives Chromosome Fragility. Cell. 2017;170:507-521.e18 pubmed 出版商
Kristoffersen E, Givskov A, Jørgensen L, Jensen P, W Byl J, Osheroff N, et al. Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events. Nucleic Acids Res. 2017;45:7855-7869 pubmed 出版商
Lopez Mosqueda J, Maddi K, Prgomet S, Kalayil S, Marinovic Terzic I, Terzic J, et al. SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks. elife. 2016;5: pubmed 出版商
Kim M, Min D, Wright G, Goldlust I, Annunziata C. Loss of compensatory pro-survival and anti-apoptotic modulator, IKKε, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21. Oncotarget. 2014;5:12788-802 pubmed
Dykhuizen E, Hargreaves D, Miller E, Cui K, Korshunov A, Kool M, et al. BAF complexes facilitate decatenation of DNA by topoisomerase II?. Nature. 2013;497:624-7 pubmed 出版商
Gardner L, Malik R, Shimizu Y, Mullins N, ElShamy W. Geminin overexpression prevents the completion of topoisomerase II? chromosome decatenation, leading to aneuploidy in human mammary epithelial cells. Breast Cancer Res. 2011;13:R53 pubmed 出版商
产品信息
目录号 :
ab52934
ItemName :
抗拓扑异构酶II甲抗体[EP1102Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP1102Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
免疫组化-P, 免疫沉淀, 免疫印迹
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。