产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗CDKN2A/p16INK4a抗体[2D9A12]
目录 :
ab54210
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2D9A12
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:1000
Azzimonti B, Raimondo L, Squarzanti D, Rosso T, Zanetta P, Aluffi Valletti P, et al. Macrophages expressing TREM-1 are involved in the progression of HPV16-related oropharyngeal squamous cell carcinoma. Ann Med. 2021;53:541-550 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 1a
Cherif H, Bisson D, Mannarino M, Rabau O, Ouellet J, Haglund L. Senotherapeutic drugs for human intervertebral disc degeneration and low back pain. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Alessio N, Squillaro T, Di Bernardo G, Galano G, De Rosa R, Melone M, et al. Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1c
  • 免疫组化-自由浮动切片; 小鼠; 1:100; 图 4d
Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler R, Zhang S, et al. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model. Nat Neurosci. 2019;22:719-728 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 3i
Ritschka B, Storer M, Mas A, Heinzmann F, Ortells M, Morton J, et al. The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration. Genes Dev. 2017;31:172-183 pubmed 出版商
  • 免疫印迹; 人类; 图 8a
Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone M, et al. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017;232:3454-3467 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 s5
Lui J, Garrison P, Nguyen Q, Ad M, Keembiyehetty C, Chen W, et al. EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy. Nat Commun. 2016;7:13685 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Mirkheshti N, Park S, Jiang S, Cropper J, Werner S, Song C, et al. Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer. Oncotarget. 2016;7:62240-62254 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Grootaert M, da Costa Martins P, Bitsch N, Pintelon I, De Meyer G, Martinet W, et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy. 2015;11:2014-2032 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Hsu C, Chen Y, Yang W, Hsu K, Chao S, Lee J. Bowen's disease with features resembling myrmecia wart. J Dermatol. 2015;42:90-3 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Wang W, Catto J, Meuth M. Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene. 2015;34:2887-96 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 3
  • 免疫印迹; 人类; 1:1000; 图 1
Philipot D, Guérit D, Platano D, Chuchana P, Olivotto E, Espinoza F, et al. p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis. Arthritis Res Ther. 2014;16:R58 pubmed 出版商
  • 免疫印迹; 人类
Zhang B, Cui S, Bai X, Zhuo L, Sun X, Hong Q, et al. SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathway. Age (Dordr). 2013;35:2237-53 pubmed 出版商
Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, et al. Redd1 knockdown prevents doxorubicin-induced cardiac senescence. Aging (Albany NY). 2021;13:13788-13806 pubmed 出版商
Huang H, Cheng T, Yang C, Chang C, Ho C, Chuang S, et al. Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis. Antioxidants (Basel). 2021;10: pubmed 出版商
Liang C, Liu Z, Song M, Li W, Wu Z, Wang Z, et al. Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration. Cell Res. 2021;31:187-205 pubmed 出版商
Alessio N, Acar M, Demirsoy I, Squillaro T, Siniscalco D, Bernardo G, et al. Obesity is associated with senescence of mesenchymal stromal cells derived from bone marrow, subcutaneous and visceral fat of young mice. Aging (Albany NY). 2020;12:12609-12621 pubmed 出版商
Yang H, Chen C, Chen H, Duan X, Li J, Zhou Y, et al. Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis. Aging (Albany NY). 2020;12:12750-12770 pubmed 出版商
Yu B, Ma J, Li J, Wang D, Wang Z, Wang S. Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics. Nat Commun. 2020;11:2549 pubmed 出版商
Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, et al. Inducing and exploiting vulnerabilities for the treatment of liver cancer. Nature. 2019;: pubmed 出版商
Alessio N, Aprile D, Squillaro T, Di Bernardo G, Finicelli M, Melone M, et al. The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells. Aging (Albany NY). 2019;11:5817-5828 pubmed 出版商
Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, et al. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. Nat Commun. 2019;10:3329 pubmed 出版商
Ghosh D, Roy A, Murmu N, Mandal S, Roy A. Risk Categorization with Different Grades of Cervical Pre-Neoplastic Lesions - High Risk HPV Associations and Expression of p53 and RARβ. Asian Pac J Cancer Prev. 2019;20:549-555 pubmed
Ovadya Y, Landsberger T, Leins H, Vadai E, Gal H, Biran A, et al. Impaired immune surveillance accelerates accumulation of senescent cells and aging. Nat Commun. 2018;9:5435 pubmed 出版商
Araya J, Tsubouchi K, Sato N, Ito S, Minagawa S, Hara H, et al. PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. Autophagy. 2018;:1-17 pubmed 出版商
Swidnicka Siergiejko A, Gomez Chou S, Cruz Monserrate Z, Deng D, Liu Y, Huang H, et al. Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53. Oncogene. 2017;36:3149-3158 pubmed 出版商
Cabral V, Cerski M, Sa Brito I, Kliemann L. p14 expression differences in ovarian benign, borderline and malignant epithelial tumors. J Ovarian Res. 2016;9:69 pubmed
Teratake Y, Kuga C, Hasegawa Y, Sato Y, Kitahashi M, Fujimura L, et al. Transcriptional repression of p27 is essential for murine embryonic development. Sci Rep. 2016;6:26244 pubmed 出版商
Uehara K, Ikehara F, Tanabe Y, Nakazato I, Oshiro M, Inamine M, et al. CD10 expression in the neuroendocrine carcinoma component of endometrial mixed carcinoma: association with long survival. Diagn Pathol. 2016;11:16 pubmed 出版商
Mohammed C, Rhee H, Phee B, Kim K, Kim H, Lee H, et al. miR-204 downregulates EphB2 in aging mouse hippocampal neurons. Aging Cell. 2016;15:380-8 pubmed 出版商
Maeda M, Hayashi T, Mizuno N, Hattori Y, Kuzuya M. Intermittent high glucose implements stress-induced senescence in human vascular endothelial cells: role of superoxide production by NADPH oxidase. PLoS ONE. 2015;10:e0123169 pubmed 出版商
Chen D, Mei L, Zhou Y, Shen C, Xu H, Niu Z, et al. A novel differential diagnostic model for multiple primary lung cancer: Differentially-expressed gene analysis of multiple primary lung cancer and intrapulmonary metastasis. Oncol Lett. 2015;9:1081-1088 pubmed
Krishnappa P, Mohamad I, Lin Y, Barua A. Expression of P16 in high-risk human papillomavirus related lesions of the uterine cervix in a government hospital, Malaysia. Diagn Pathol. 2014;9:202 pubmed 出版商
Qin S, Li Q, Zhou J, Liu Z, Su N, Wilson J, et al. Homeostatic maintenance of allele-specific p16 methylation in cancer cells accompanied by dynamic focal methylation and hydroxymethylation. PLoS ONE. 2014;9:e97785 pubmed 出版商
Federico A, Forzati F, Esposito F, Arra C, Palma G, Barbieri A, et al. Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotype. Biol Open. 2014;3:372-8 pubmed 出版商
产品信息
目录号 :
ab54210
ItemName :
抗CDKN2A/p16INK4a抗体[2D9A12]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
2D9A12
规格 :
100微升
物种摘要 :
Hu, Ms, Rat
纯度 :
蛋白质G纯化
应用摘要 :
ELISA, Flow Cyt, IHC-P
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。