产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗DRP1抗体
目录 :
ab56788
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
African green monkey, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫印迹基因敲除验证, 免疫细胞化学基因敲除验证
文章摘录数: 41
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:750; 图 7d
  • 免疫印迹; 小鼠; 1:500-1:2000; 图 5a
Chiang S, Braidy N, Maleki S, Lal S, Richardson D, Huang M. Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation. Redox Biol. 2021;46:102038 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4d
Kuroda R, Tominaga K, Kasashima K, Kuroiwa K, Sakashita E, Hayakawa H, et al. Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo. PLoS ONE. 2021;16:e0255355 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4h
Tian F, Zhang Y. Overexpression of SERCA2a Alleviates Cardiac Microvascular Ischemic Injury by Suppressing Mfn2-Mediated ER/Mitochondrial Calcium Tethering. Front Cell Dev Biol. 2021;9:636553 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3g
Ghosh A, Bhattacharjee S, Chowdhuri S, Mallick A, Rehman I, Basu S, et al. SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy. Sci Adv. 2019;5:eaax9778 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3c
Zhao H, Pan W, Chen L, Luo Y, Xu R. Nur77 promotes cerebral ischemia-reperfusion injury via activating INF2-mediated mitochondrial fragmentation. J Mol Histol. 2018;49:599-613 pubmed 出版商
  • 免疫印迹; 人类; 图 e4
Lee S, Singh I, Tisdale S, Abdel Wahab O, Leslie C, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018;561:127-131 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2h
  • 免疫印迹; 人类; 图 1g
Malty R, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, et al. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017;5:564-577.e12 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Kelly F, Wei B, Cygan A, Parker M, Boulanger M, Boothroyd J. Toxoplasma gondii MAF1b Binds the Host Cell MIB Complex To Mediate Mitochondrial Association. mSphere. 2017;2: pubmed 出版商
  • 免疫细胞化学基因敲除验证; 人类; 图 s3
Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
  • 免疫印迹; 人类; 图 1b
  • 免疫细胞化学; African green monkey; 图 sf4
Lee J, Westrate L, Wu H, Page C, Voeltz G. Multiple dynamin family members collaborate to drive mitochondrial division. Nature. 2016;540:139-143 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Franco A, Kitsis R, Fleischer J, Gavathiotis E, Kornfeld O, Gong G, et al. Correcting mitochondrial fusion by manipulating mitofusin conformations. Nature. 2016;540:74-79 pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 1
  • 免疫印迹; 人类; 1:800; 图 3
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s12
Gong G, Song M, Csordás G, Kelly D, Matkovich S, Dorn G. Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice. Science. 2015;350:aad2459 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 1c
Song M, Gong G, Burelle Y, Gustafsson Ã, Kitsis R, Matkovich S, et al. Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts. Circ Res. 2015;117:346-51 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Fan S, Liu B, Sun L, Lv X, Lin Z, Chen W, et al. Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p-MFF axis. Oncotarget. 2015;6:14885-904 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Pant M, Sopariwala D, Bal N, Lowe J, Delfín D, RAFAEL FORTNEY J, et al. Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy. PLoS ONE. 2015;10:e0123875 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 1
Song M, Mihara K, Chen Y, Scorrano L, Dorn G. Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts. Cell Metab. 2015;21:273-85 pubmed 出版商
Yu B, Ma J, Li J, Wang D, Wang Z, Wang S. Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics. Nat Commun. 2020;11:2549 pubmed 出版商
Heden T, Johnson J, Ferrara P, Eshima H, Verkerke A, Wentzler E, et al. Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv. 2019;5:eaax8352 pubmed 出版商
Zhang X, Li F, Cui Y, Liu S, Sun H. Mst1 overexpression combined with Yap knockdown augments thyroid carcinoma apoptosis via promoting MIEF1-related mitochondrial fission and activating the JNK pathway. Cancer Cell Int. 2019;19:143 pubmed 出版商
Smith G, Lin T, Sheehan A, Van der Goes van Naters W, Neukomm L, Graves H, et al. Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation. Neuron. 2019;: pubmed 出版商
Ward J, Stoyas C, Switonski P, Ichou F, Fan W, Collins B, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019;26:1189-1202.e6 pubmed 出版商
Ganesan V, Willis S, Chang K, Beluch S, Cooper K, Strich R. Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission. Mol Biol Cell. 2019;30:302-311 pubmed 出版商
Cesnekova J, Rodinova M, Hansikova H, Zeman J, Stiburek L. Loss of Mitochondrial AAA Proteases AFG3L2 and YME1L Impairs Mitochondrial Structure and Respiratory Chain Biogenesis. Int J Mol Sci. 2018;19: pubmed 出版商
Ding X, Sun W, Chen J. IL-2 augments the sorafenib-induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway. Cancer Cell Int. 2018;18:176 pubmed 出版商
Burdyga A, Surdo N, Monterisi S, Di Benedetto G, Grisan F, Penna E, et al. Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane. Proc Natl Acad Sci U S A. 2018;115:E6497-E6506 pubmed 出版商
Wang X, Song Q. Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway. Cell Mol Biol Lett. 2018;23:21 pubmed 出版商
Ryan Z, Craig T, Wang X, Delmotte P, Salisbury J, Lanza I, et al. 1α,25-dihydroxyvitamin D3 mitigates cancer cell mediated mitochondrial dysfunction in human skeletal muscle cells. Biochem Biophys Res Commun. 2018;496:746-752 pubmed 出版商
Marín Royo G, Gallardo I, Martínez Martínez E, Gutierrez B, Jurado López R, Lopez Andres N, et al. Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity. Dis Model Mech. 2018;11: pubmed 出版商
Helle S, Feng Q, Aebersold M, Hirt L, Grüter R, Vahid A, et al. Mechanical force induces mitochondrial fission. elife. 2017;6: pubmed 出版商
Rostami J, Holmqvist S, Lindström V, Sigvardson J, Westermark G, Ingelsson M, et al. Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes. J Neurosci. 2017;37:11835-11853 pubmed 出版商
Zhou B, Wen M, Lin X, Chen Y, Gou Y, Li Y, et al. Alpha Lipoamide Ameliorates Motor Deficits and Mitochondrial Dynamics in the Parkinson's Disease Model Induced by 6-Hydroxydopamine. Neurotox Res. 2018;33:759-767 pubmed 出版商
Yi C, Walter M, Gao Y, Pitra S, Legutko B, Kälin S, et al. TNFα drives mitochondrial stress in POMC neurons in obesity. Nat Commun. 2017;8:15143 pubmed 出版商
Jones E, Gaytan N, Garcia I, Herrera A, Ramos M, Agarwala D, et al. A threshold of transmembrane potential is required for mitochondrial dynamic balance mediated by DRP1 and OMA1. Cell Mol Life Sci. 2017;74:1347-1363 pubmed 出版商
Stefanova N, Muraleva N, Maksimova K, Rudnitskaya E, Kiseleva E, Telegina D, et al. An antioxidant specifically targeting mitochondria delays progression of Alzheimer's disease-like pathology. Aging (Albany NY). 2016;8:2713-2733 pubmed 出版商
Lu Y, Li S, Wu H, Bian Z, Xu J, Gu C, et al. Beneficial effects of astragaloside IV against angiotensin II-induced mitochondrial dysfunction in rat vascular smooth muscle cells. Int J Mol Med. 2015;36:1223-32 pubmed 出版商
Ahmad T, Sundar I, Lerner C, Gerloff J, Tormos A, Yao H, et al. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. FASEB J. 2015;29:2912-29 pubmed 出版商
Onoguchi K, Onomoto K, Takamatsu S, Jogi M, Takemura A, Morimoto S, et al. Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1. PLoS Pathog. 2010;6:e1001012 pubmed 出版商
Uittenbogaard M, Baxter K, Chiaramello A. The neurogenic basic helix-loop-helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass. ASN Neuro. 2010;2:e00034 pubmed 出版商
产品信息
目录号 :
ab56788
ItemName :
抗DRP1抗体
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
规格 :
100微克
物种摘要 :
Hu, Rat
纯度 :
蛋白质G纯化
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。