| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫组化-石蜡切片; 小鼠; 1:500; 图 2a
- 免疫印迹; 小鼠; 1:1000; 图 2c
| Tang Y, Dong L, Zhang C, Li X, Li R, Lin H, et al. PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis. Int J Biol Sci. 2022;18:4329-4340 pubmed 出版商 |
- 染色质免疫沉淀
; 小鼠; 图 7e
- 免疫印迹; 小鼠; 1:1000; 图 6a
| Dong F, Chen M, Jiang L, Shen Z, Ma L, Han C, et al. PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications. Front Cell Dev Biol. 2021;9:673258 pubmed 出版商 |
| Demetriadou C, Pavlou D, Mpekris F, Achilleos C, Stylianopoulos T, Zaravinos A, et al. NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression. Cell Death Dis. 2019;10:236 pubmed 出版商 |
- 染色质免疫沉淀
; 人类; 图 2c
- 免疫印迹; 人类; 图 2c
| Deng X, Shao G, Zhang H, Li C, Zhang D, Cheng L, et al. Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth. Oncogene. 2017;36:1223-1231 pubmed 出版商 |
| Zhang J, Fan X, Zhou Y, Chen L, Rao H. The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression. J Exp Clin Cancer Res. 2022;41:191 pubmed 出版商 |
| Gao Y, Ge W. The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis. Cell Death Dis. 2018;9:33 pubmed 出版商 |
| Rengasamy M, Zhang F, Vashisht A, Song W, Aguilo F, Sun Y, et al. The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer. Nucleic Acids Res. 2017;45:11106-11120 pubmed 出版商 |
| Saha K, Fisher M, Adhikary G, Grun D, Eckert R. Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation. Carcinogenesis. 2017;38:827-836 pubmed 出版商 |
| Kaushik S, Liu F, Veazey K, Gao G, Das P, Neves L, et al. Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML. Leukemia. 2018;32:499-509 pubmed 出版商 |
| Patel S, Bhumbra S, Paknikar R, Dressler G. Epigenetic mechanisms of Groucho/Grg/TLE mediated transcriptional repression. Mol Cell. 2012;45:185-95 pubmed 出版商 |
