Kim J, Hwang K, Dang B, Eom M, Kong I, Gwack Y, et al. Insulin-activated store-operated Ca2+ entry via Orai1 induces podocyte actin remodeling and causes proteinuria. Nat Commun. 2021;12:6537 pubmed 出版商

Truong D, Phlairaharn T, Eßwein B, Gruber C, Tümen D, Baligács E, et al. Non-invasive and high-throughput interrogation of exon-specific isoform expression. Nat Cell Biol. 2021;23:652-663 pubmed 出版商

Hanna B, Michel M, Helleday T, Mortusewicz O. NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487. Int J Mol Sci. 2021;22: pubmed 出版商

Miles R, Kerridge C, Hilditch L, Monit C, Jacques D, Towers G. MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface. elife. 2020;9: pubmed 出版商

Wang Y, Chiang I, Ohara T, Fujii S, Cheng J, Muegge B, et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. 2019;179:1144-1159.e15 pubmed 出版商

Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed 出版商

Chakrabarti R, Celià Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, et al. Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche. Science. 2018;360: pubmed 出版商

Ross Adams H, Ball S, Lawrenson K, Halim S, Russell R, Wells C, et al. HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer. Oncotarget. 2016;7:74734-74746 pubmed 出版商

Liu Z, Tian R, Li Y, Zhang L, Shao H, Yang C, et al. SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia. Sci Rep. 2016;6:34416 pubmed 出版商

Doan K, Kinyua A, Yang D, Ko C, Moh S, Shong K, et al. FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase. Nat Commun. 2016;7:12733 pubmed 出版商

Caporali P, Bruno F, Palladino G, Dragotto J, Petrosini L, Mangia F, et al. Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis. Acta Neuropathol Commun. 2016;4:94 pubmed 出版商

Kaliberov S, Kaliberova L, Yan H, Kapoor V, Hallahan D. Retargeted adenoviruses for radiation-guided gene delivery. Cancer Gene Ther. 2016;23:303-14 pubmed 出版商

Ni T, Liu Y, Peng Y, Li M, Fang Y, Yao M. Substance P induces inflammatory responses involving NF-?B in genetically diabetic mice skin fibroblasts co-cultured with macrophages. Am J Transl Res. 2016;8:2179-88 pubmed

Gray M, Lee S, McDowell A, Erskine M, Loh Q, Grice O, et al. Dual targeting of EGFR and ERBB2 pathways produces a synergistic effect on cancer cell proliferation and migration in vitro. Vet Comp Oncol. 2017;15:890-909 pubmed 出版商

Ni T, Kuperwasser C. Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. elife. 2016;5: pubmed 出版商

Flodby P, Kim Y, Beard L, Gao D, Ji Y, Kage H, et al. Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance. Am J Respir Cell Mol Biol. 2016;55:395-406 pubmed 出版商

Wang X, Zhang X, Zhou T, Li N, Jang C, Xiao Z, et al. Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ1-42. Front Neurosci. 2016;10:94 pubmed 出版商

Yousuf M, Tan C, Torres Altoro M, Lu F, Plautz E, Zhang S, et al. Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury. J Neurochem. 2016;138:317-27 pubmed 出版商

Prause M, Mayer C, Brorsson C, Frederiksen K, Billestrup N, Størling J, et al. JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression. J Diabetes Res. 2016;2016:1312705 pubmed 出版商

Lasek A, McPherson B, Trueman N, Burkard M. The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation. PLoS ONE. 2016;11:e0150225 pubmed 出版商

Krause C, Popp O, Thirunarayanan N, Dittmar G, Lipp M, Müller G. MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR. Oncotarget. 2016;7:10414-32 pubmed 出版商

Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed 出版商

Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed 出版商

Binolfi A, Limatola A, Verzini S, Kosten J, Theillet F, Rose H, et al. Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites. Nat Commun. 2016;7:10251 pubmed 出版商

Park S, Jeong S. SRSF3 represses the expression of PDCD4 protein by coordinated regulation of alternative splicing, export and translation. Biochem Biophys Res Commun. 2016;470:431-438 pubmed 出版商

Smith K, Zhou B, Avdulov S, Benyumov A, Peterson M, Liu Y, et al. Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E. Sci Rep. 2015;5:18233 pubmed 出版商

Yin K, Lei Y, Wen X, Lacruz R, Soleimani M, Kurtz I, et al. SLC26A Gene Family Participate in pH Regulation during Enamel Maturation. PLoS ONE. 2015;10:e0144703 pubmed 出版商

Suica V, Uyy E, Boteanu R, Ivan L, Antohe F. Alteration of actin dependent signaling pathways associated with membrane microdomains in hyperlipidemia. Proteome Sci. 2015;13:30 pubmed 出版商

Fleury H, Communal L, Carmona E, Portelance L, Arcand S, Rahimi K, et al. Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease. Genes Cancer. 2015;6:378-398 pubmed

Bo Q, Sun X, Liu J, Sui X, Li G. Antitumor action of the peroxisome proliferator-activated receptor-γ agonist rosiglitazone in hepatocellular carcinoma. Oncol Lett. 2015;10:1979-1984 pubmed

Wanzel M, Vischedyk J, Gittler M, Gremke N, Seiz J, Hefter M, et al. CRISPR-Cas9-based target validation for p53-reactivating model compounds. Nat Chem Biol. 2016;12:22-8 pubmed 出版商

Xu S, Nam S, Kim J, Das R, Choi S, Nguyen T, et al. Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress. Cell Death Dis. 2015;6:e1976 pubmed 出版商

Zampieri A, Champagne J, Auzemery B, Fuentes I, Maurel B, Bienvenu F. Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse. Sci Rep. 2015;5:15739 pubmed 出版商

Tajerian M, Leu D, Yang P, Huang T, Kingery W, Clark J. Differential Efficacy of Ketamine in the Acute versus Chronic Stages of Complex Regional Pain Syndrome in Mice. Anesthesiology. 2015;123:1435-47 pubmed 出版商

DeNicola G, Chen P, Mullarky E, Sudderth J, Hu Z, Wu D, et al. NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nat Genet. 2015;47:1475-81 pubmed 出版商

Bauskar A, Mack W, Mauris J, Argüeso P, Heur M, Nagel B, et al. Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS ONE. 2015;10:e0138958 pubmed 出版商

Darr J, Klochendler A, Isaac S, Geiger T, Geiger T, Eden A. Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells. Mol Cancer. 2015;14:167 pubmed 出版商

Lund R, Leth Larsen R, Caterino T, Terp M, Nissen J, Lænkholm A, et al. NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer. Mol Cell Proteomics. 2015;14:2988-99 pubmed 出版商

Simpson M, Venkatesh I, Callif B, Thiel L, Coley D, Winsor K, et al. The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons. Mol Cell Neurosci. 2015;68:272-83 pubmed 出版商

Garwood C, Ratcliffe L, Morgan S, Simpson J, Owens H, Vazquez Villaseñor I, et al. Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors. Mol Brain. 2015;8:51 pubmed 出版商

Kim S, Lee K, Choi J, Ringstad N, Dynlacht B. Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle. Nat Commun. 2015;6:8087 pubmed 出版商

Liu H, Li Y, Wang Y, Wang X, An X, Wang S, et al. The distinct role of NR2B subunit in the enhancement of visual plasticity in adulthood. Mol Brain. 2015;8:49 pubmed 出版商

Kim J, Sato M, Choi J, Kim H, Yeh B, Larsen J, et al. Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis. PLoS ONE. 2015;10:e0134842 pubmed 出版商

Johansson I, Monsen V, Pettersen K, Mildenberger J, Misund K, Kaarniranta K, et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy. 2015;11:1636-51 pubmed 出版商

Cao Q, Yamamoto J, Isobe T, Tateno S, Murase Y, Chen Y, et al. Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Nonoverlapping Functions of Rtf1 and the Paf1 Complex. Mol Cell Biol. 2015;35:3459-70 pubmed 出版商

Regan J, Kannan P, Kemp M, Kramer B, Newnham J, Jobe A, et al. Damage-Associated Molecular Pattern and Fetal Membrane Vascular Injury and Collagen Disorganization in Lipopolysaccharide-Induced Intra-amniotic Inflammation in Fetal Sheep. Reprod Sci. 2016;23:69-80 pubmed 出版商

Chan M, Atasoylu O, Hodson E, Tumber A, Leung I, Chowdhury R, et al. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. PLoS ONE. 2015;10:e0132004 pubmed 出版商

Yang X, Zheng K, Lin K, Zheng G, Zou H, Wang J, et al. Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study. PLoS ONE. 2015;10:e0132695 pubmed 出版商

Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 2015;6:7505 pubmed 出版商

de Jager M, Drukarch B, Hofstee M, Brevé J, Jongenelen C, Bol J, et al. Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity. J Neurochem. 2015;134:1116-28 pubmed 出版商

Durham T, Toth J, Klimkowski V, Cao J, Siesky A, Alexander Chacko J, et al. Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J Biol Chem. 2015;290:20044-59 pubmed 出版商

Ramljak S, Schmitz M, Zafar S, Wrede A, Schenkel S, Asif A, et al. Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions. Exp Neurol. 2015;271:155-67 pubmed 出版商

Krais A, Speksnijder E, Melis J, Indra R, Moserova M, Godschalk R, et al. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Arch Toxicol. 2016;90:839-51 pubmed 出版商

Bai Y, Xuan B, Liu H, Zhong J, Yu D, Qian Z. Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38. J Virol. 2015;89:7625-35 pubmed 出版商

Saini P, Li Y, Dobbelstein M. Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. Oncotarget. 2015;6:13072-87 pubmed

Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed 出版商

Piskareva O, Harvey H, Nolan J, Conlon R, Alcock L, Buckley P, et al. The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro. Cancer Lett. 2015;364:142-55 pubmed 出版商

Li J, Jørgensen S, Maggadottir S, Bakay M, Warnatz K, Glessner J, et al. Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. Nat Commun. 2015;6:6804 pubmed 出版商

Markkanen E, Fischer R, Ledentcova M, Kessler B, Dianov G. Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability. Nucleic Acids Res. 2015;43:3667-79 pubmed 出版商

Khoronenkova S, Dianov G. ATM prevents DSB formation by coordinating SSB repair and cell cycle progression. Proc Natl Acad Sci U S A. 2015;112:3997-4002 pubmed 出版商

Wnorowski A, Sadowska M, Paul R, Singh N, Boguszewska Czubara A, Jimenez L, et al. Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells. Cell Signal. 2015;27:997-1007 pubmed 出版商

Mbefo M, Fares M, Paleologou K, Oueslati A, Yin G, Tenreiro S, et al. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. J Biol Chem. 2015;290:9412-27 pubmed 出版商

Hedgepeth S, Garcia M, Wagner L, Rodriguez A, Chintapalli S, Snyder R, et al. The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release. J Biol Chem. 2015;290:7304-13 pubmed 出版商

Chucair Elliott A, Zheng M, Carr D. Degeneration and regeneration of corneal nerves in response to HSV-1 infection. Invest Ophthalmol Vis Sci. 2015;56:1097-107 pubmed 出版商

Gao Z, Zhang J, Henagan T, Lee J, Ye X, Wang H, et al. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015;308:E496-505 pubmed 出版商

Quan X, Nguyen T, Choi S, Xu S, Das R, Cha S, et al. Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells. J Biol Chem. 2015;290:4086-96 pubmed 出版商

Cebulla J, Huuse E, Pettersen K, van der Veen A, Kim E, Andersen S, et al. MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity. Br J Cancer. 2015;112:504-13 pubmed 出版商

Ozmen A, Unek G, Kipmen Korgun D, Cetinkaya B, Avcil Z, Korgun E. Glucocorticoid exposure altered angiogenic factor expression via Akt/mTOR pathway in rat placenta. Ann Anat. 2015;198:34-40 pubmed 出版商

Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, et al. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med. 2015;78:202-12 pubmed 出版商

Holloway A, Simmonds M, Azad A, Fox J, Storey A. Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase. Int J Cancer. 2015;136:2831-43 pubmed 出版商

Wohak L, Krais A, Kucab J, Stertmann J, Øvrebø S, Seidel A, et al. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism. Arch Toxicol. 2016;90:291-304 pubmed 出版商

Berghold V, Gauster M, Hemmings D, Moser G, Kremshofer J, Siwetz M, et al. Phospholipid scramblase 1 (PLSCR1) in villous trophoblast of the human placenta. Histochem Cell Biol. 2015;143:381-96 pubmed 出版商

Blaabjerg L, Christensen G, Matsumoto M, van der Meulen T, Huising M, Billestrup N, et al. CRFR1 activation protects against cytokine-induced β-cell death. J Mol Endocrinol. 2014;53:417-27 pubmed 出版商

Forny Germano L, Lyra e Silva N, Batista A, Brito Moreira J, Gralle M, Boehnke S, et al. Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates. J Neurosci. 2014;34:13629-43 pubmed 出版商

Xu W, Yang X, Li D, Zheng K, Qiu P, Zhang W, et al. Up-regulation of fatty acid oxidation in the ligament as a contributing factor of ankylosing spondylitis: A comparative proteomic study. J Proteomics. 2015;113:57-72 pubmed 出版商

Lucken Ardjomande Häsler S, Vallis Y, Jolin H, McKenzie A, McMahon H. GRAF1a is a brain-specific protein that promotes lipid droplet clustering and growth, and is enriched at lipid droplet junctions. J Cell Sci. 2014;127:4602-19 pubmed 出版商

Tajerian M, Leu D, Zou Y, Sahbaie P, Li W, Khan H, et al. Brain neuroplastic changes accompany anxiety and memory deficits in a model of complex regional pain syndrome. Anesthesiology. 2014;121:852-65 pubmed 出版商

Charan R, Johnson B, Zaganelli S, Nardozzi J, LaVoie M. Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin. Cell Death Dis. 2014;5:e1313 pubmed 出版商

Pardee T, Stadelman K, Jennings Gee J, Caudell D, Gmeiner W. The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells. Oncotarget. 2014;5:4170-9 pubmed

Macdonald E, Urbé S, Clague M. USP8 controls the trafficking and sorting of lysosomal enzymes. Traffic. 2014;15:879-88 pubmed 出版商

Tape C, Norrie I, Worboys J, Lim L, Lauffenburger D, Jørgensen C. Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture. Mol Cell Proteomics. 2014;13:1866-76 pubmed 出版商

Chu D, Malinowska E, Gawronska Kozak B, Kozak L. Expression of adipocyte biomarkers in a primary cell culture models reflects preweaning adipobiology. J Biol Chem. 2014;289:18478-88 pubmed 出版商

Chucair Elliott A, Conrady C, Zheng M, Kroll C, Lane T, Carr D. Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells. Glia. 2014;62:1418-34 pubmed 出版商

Siwetz M, Blaschitz A, Kremshofer J, Bilic J, Desoye G, Huppertz B, et al. Metalloprotease dependent release of placenta derived fractalkine. Mediators Inflamm. 2014;2014:839290 pubmed 出版商

Wei X, Ke B, Zhao Z, Ye X, Gao Z, Ye J. Regulation of insulin degrading enzyme activity by obesity-associated factors and pioglitazone in liver of diet-induced obese mice. PLoS ONE. 2014;9:e95399 pubmed 出版商

Bhansali M, Shemshedini L. COP9 subunits 4 and 5 target soluble guanylyl cyclase ?1 and p53 in prostate cancer cells. Mol Endocrinol. 2014;28:834-45 pubmed 出版商

Bejarano E, Yuste A, Patel B, Stout R, Spray D, Cuervo A. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 2014;16:401-14 pubmed 出版商

Glorieux C, Auquier J, Dejeans N, Sid B, Demoulin J, Bertrand L, et al. Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway. Biochem Pharmacol. 2014;89:217-23 pubmed 出版商

Tashima Y, Stanley P. Antibodies that detect O-linked ?-D-N-acetylglucosamine on the extracellular domain of cell surface glycoproteins. J Biol Chem. 2014;289:11132-42 pubmed 出版商

Dannoura A, Giraldo A, Pereira I, Gibbins J, Dash P, Bicknell K, et al. Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor ?. J Pharm Pharmacol. 2014;66:779-92 pubmed 出版商

Tsuneki M, Madri J. CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression. J Biol Chem. 2014;289:5357-70 pubmed 出版商

Ustunel I, Acar N, Gemici B, Ozbey O, Edizer I, Soylu H, et al. The effects of water immersion and restraint stress on the expressions of apelin, apelin receptor (APJR) and apoptosis rate in the rat heart. Acta Histochem. 2014;116:675-81 pubmed 出版商

Evers M, Tran H, Zalachoras I, Meijer O, den Dunnen J, van Ommen G, et al. Preventing formation of toxic N-terminal huntingtin fragments through antisense oligonucleotide-mediated protein modification. Nucleic Acid Ther. 2014;24:4-12 pubmed 出版商

Yang Q, Yu C, Yang Z, Wei Q, Mu K, Zhang Y, et al. Deregulated NLRP3 and NLRP1 inflammasomes and their correlations with disease activity in systemic lupus erythematosus. J Rheumatol. 2014;41:444-52 pubmed 出版商

Larson A, Lee C, Lezcano C, Zhan Q, Huang J, Fischer A, et al. Melanoma spheroid formation involves laminin-associated vasculogenic mimicry. Am J Pathol. 2014;184:71-8 pubmed 出版商

Park R, Chen J, Kim J, Jeong S, Ohn T. Splicing factor SRSF3 represses the translation of programmed cell death 4 mRNA by associating with the 5'-UTR region. Cell Death Differ. 2014;21:481-90 pubmed 出版商

Wei Q, Mu K, Li T, Zhang Y, Yang Z, Jia X, et al. Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression. Lab Invest. 2014;94:52-62 pubmed 出版商

Thrasivoulou C, Millar M, Ahmed A. Activation of intracellular calcium by multiple Wnt ligands and translocation of ?-catenin into the nucleus: a convergent model of Wnt/Ca2+ and Wnt/?-catenin pathways. J Biol Chem. 2013;288:35651-9 pubmed 出版商

Epis M, Giles K, Candy P, Webster R, Leedman P. miR-331-3p regulates expression of neuropilin-2 in glioblastoma. J Neurooncol. 2014;116:67-75 pubmed 出版商

Nkyimbeng T, Ruppert C, Shiomi T, Dahal B, Lang G, Seeger W, et al. Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis. PLoS ONE. 2013;8:e73279 pubmed 出版商

Andersen S, Baar C, Fladvad T, Laugsand E, Skorpen F. The N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene. PLoS ONE. 2013;8:e71024 pubmed 出版商

Maunakea A, Chepelev I, Cui K, Zhao K. Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition. Cell Res. 2013;23:1256-69 pubmed 出版商

Luo L, Uehara H, Zhang X, Das S, Olsen T, Holt D, et al. Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. elife. 2013;2:e00324 pubmed 出版商

Hartsink Segers S, Exalto C, Allen M, Williamson D, Clifford S, Horstmann M, et al. Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells. Haematologica. 2013;98:1539-46 pubmed 出版商

Shen H, Liao K, Zhang W, Wu H, Shen B, Xu Z. Differential expression of peroxiredoxin 6, annexin A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1 in testis of rat fetuses after maternal exposure to di-n-butyl phthalate. Reprod Toxicol. 2013;39:76-84 pubmed 出版商

Oshikawa M, Okada K, Nakajima K, Ajioka I. Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development. 2013;140:2310-20 pubmed 出版商

Sappino A, Buser R, Seguin Q, Fernet M, Lesne L, Gumy Pause F, et al. The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage. Oncogenesis. 2012;1:e7 pubmed 出版商

Smith A, Gibbons H, Oldfield R, Bergin P, Mee E, Faull R, et al. The transcription factor PU.1 is critical for viability and function of human brain microglia. Glia. 2013;61:929-42 pubmed 出版商

Heo S, Choi J, Kim Y, Jung C, Lee J, Jin H, et al. Comparative proteomic analysis in children with idiopathic short stature (ISS) before and after short-term recombinant human growth hormone (rhGH) therapy. Proteomics. 2013;13:1211-9 pubmed 出版商

Lu B, Palacino J. A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration. FASEB J. 2013;27:1820-9 pubmed 出版商

Khoronenkova S, Dianov G. USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair. Nucleic Acids Res. 2013;41:1750-6 pubmed 出版商

Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, et al. CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication. Genes Cells. 2012;17:962-70 pubmed 出版商

Hartsink Segers S, Zwaan C, Exalto C, Luijendijk M, Calvert V, Petricoin E, et al. Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target. Leukemia. 2013;27:560-8 pubmed 出版商

Akhrymuk I, Kulemzin S, Frolova E. Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II. J Virol. 2012;86:7180-91 pubmed 出版商

Gu B, Watanabe K, Dai X. Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells. Cell Cycle. 2012;11:79-87 pubmed 出版商

Gauster M, Siwetz M, Huppertz B. Fusion of villous trophoblast can be visualized by localizing active caspase 8. Placenta. 2009;30:547-50 pubmed 出版商

Strååt K, de Klark R, Gredmark Russ S, Eriksson P, Soderberg Naucler C. Infection with human cytomegalovirus alters the MMP-9/TIMP-1 balance in human macrophages. J Virol. 2009;83:830-5 pubmed 出版商

Nair M, Nagamori I, Sun P, Mishra D, Rhéaume C, Li B, et al. Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation. Dev Biol. 2008;320:446-55 pubmed 出版商

Christian M, Kiskinis E, Debevec D, Leonardsson G, White R, Parker M. RIP140-targeted repression of gene expression in adipocytes. Mol Cell Biol. 2005;25:9383-91 pubmed

Perez García V, Lea G, Lopez Jimenez P, Okkenhaug H, Burton G, Moffett A, et al. BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion. elife. 2021;10: pubmed 出版商

Xu J, Guo S, Xue R, Xiao L, Kou J, Liu Y, et al. Adalimumab ameliorates memory impairments and neuroinflammation in chronic cerebral hypoperfusion rats. Aging (Albany NY). 2021;13:14001-14014 pubmed 出版商

He Y, Wang R, Zhang P, Yan J, Gong N, Li Y, et al. Curcumin inhibits the proliferation and migration of vascular smooth muscle cells by targeting the chemerin / CMKLR1 / LCN2 axis. Aging (Albany NY). 2021;13:13859-13875 pubmed 出版商

Silva Pinheiro P, Pardo Hernández C, Reyes A, Tilokani L, Mishra A, Cerutti R, et al. DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion. Nucleic Acids Res. 2021;49:5230-5248 pubmed 出版商

Baquero J, Benitez Buelga C, Rajagopal V, Zhenjun Z, Torres Ruiz R, Muller S, et al. Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects. Sci Rep. 2021;11:3490 pubmed 出版商

Na J, Newman J, Then C, Syed J, Vendrell I, Torrecilla I, et al. SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells. Cell Death Dis. 2021;12:165 pubmed 出版商

Tao B, Song Y, Wu Y, Yang X, Peng T, Peng L, et al. Matrix stiffness promotes glioma cell stemness by activating BCL9L/Wnt/β-catenin signaling. Aging (Albany NY). 2021;13:5284-5296 pubmed 出版商

Habekost M, Qvist P, Denham M, Holm I, Jørgensen A. Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration. Mol Neurobiol. 2021;: pubmed 出版商

Glorieux C, Xia X, He Y, Hu Y, Cremer K, Robert A, et al. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021;38:101780 pubmed 出版商

Bai B, Lu N, Zhang W, Lin J, Zhao T, Zhou S, et al. Inhibitory Effects of Genistein on Vascular Smooth Muscle Cell Proliferation Induced by Ox-LDL: Role of BKCa Channels. Anal Cell Pathol (Amst). 2020;2020:8895449 pubmed 出版商

El Hayek L, Tuncay I, Nijem N, Russell J, Ludwig S, Kaur K, et al. KDM5A mutations identified in autism spectrum disorder using forward genetics. elife. 2020;9: pubmed 出版商

Zhu X, Han J, Lan H, Lin Q, Wang Y, Sun X. A novel circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 pathway regulates cisplatin-resistance in non-small cell lung cancer (NSCLC). BMC Cancer. 2020;20:1190 pubmed 出版商

Kim E, Ridlo M, Lee B, Kim G. Melatonin-Nrf2 Signaling Activates Peroxisomal Activities in Porcine Cumulus Cell-Oocyte Complexes. Antioxidants (Basel). 2020;9: pubmed 出版商

Sun C, Huang S, Hou Y, Li Z, Xia D, Zhang L, et al. Long noncoding RNA AC092171.4 promotes hepatocellular carcinoma progression by sponging microRNA-1271 and upregulating GRB2. Aging (Albany NY). 2020;12: pubmed 出版商

Rusilowicz Jones E, Jardine J, Kallinos A, Pinto Fernandez A, Guenther F, Giurrandino M, et al. USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation. Life Sci Alliance. 2020;3: pubmed 出版商

Liu L, Wu J, Gao Y, Lv Y, Xue J, Qin L, et al. The effect of Acot2 overexpression or downregulation on the preadipocyte differentiation in Chinese Red Steppe cattle. Adipocyte. 2020;9:279-289 pubmed 出版商

Noda T, Lu Y, Fujihara Y, Oura S, Koyano T, Kobayashi S, et al. Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice. Proc Natl Acad Sci U S A. 2020;117:11493-11502 pubmed 出版商

Dobolyi A, Bagó A, Palkovits M, Nemeria N, Jordan F, Doczi J, et al. Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation. Brain Struct Funct. 2020;225:639-667 pubmed 出版商

Li B, Clohisey S, Chia B, Wang B, Cui A, Eisenhaure T, et al. Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection. Nat Commun. 2020;11:164 pubmed 出版商

Chen J, Chen J, Huang J, Li Z, Gong Y, Zou B, et al. HIF-2α upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway. Aging (Albany NY). 2019;11:10839-10860 pubmed 出版商

Elder E, Krishna B, Williamson J, Lim E, Poole E, Sedikides G, et al. Interferon-Responsive Genes Are Targeted during the Establishment of Human Cytomegalovirus Latency. MBio. 2019;10: pubmed 出版商

Liu D, Ma Z, Xu L, Zhang X, Qiao S, Yuan J. PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades. Aging (Albany NY). 2019;11:10061-10073 pubmed 出版商

Li J, Wang Q, Yang Y, Lei C, Yang F, Liang L, et al. GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway. J Exp Clin Cancer Res. 2019;38:438 pubmed 出版商

Singh A, Oehler J, Torrecilla I, Kilgas S, Li S, Vaz B, et al. The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8. EMBO J. 2019;38:e102361 pubmed 出版商

Radzisheuskaya A, Shliaha P, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, et al. PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia. Nat Struct Mol Biol. 2019;26:999-1012 pubmed 出版商

Roman Rodriguez F, Ugalde L, Alvarez L, Díez B, Ramirez M, Risueño C, et al. NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia. Cell Stem Cell. 2019;25:607-621.e7 pubmed 出版商

Glorieux C, Buc Calderon P. Cancer Cell Sensitivity to Redox-Cycling Quinones is Influenced by NAD(P)H: Quinone Oxidoreductase 1 Polymorphism. Antioxidants (Basel). 2019;8: pubmed 出版商

Johansson J, Karema Jokinen V, Hakanen S, Jylhä A, Uusitalo H, Vihinen Ranta M, et al. Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium. BMC Biol. 2019;17:63 pubmed 出版商

Zaoui K, Boudhraa Z, Khalifé P, Carmona E, Provencher D, Mes Masson A. Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion. Nat Commun. 2019;10:2666 pubmed 出版商

Xu F, Li H, Hu C. LIFR-AS1 modulates Sufu to inhibit cell proliferation and migration by miR-197-3p in breast cancer. Biosci Rep. 2019;: pubmed 出版商

Lefort C, Van Hul M, Delzenne N, Everard A, Cani P. Hepatic MyD88 regulates liver inflammation by altering synthesis of oxysterols. Am J Physiol Endocrinol Metab. 2019;317:E99-E108 pubmed 出版商

Lai Y, Zhu B, Sun F, Luo D, Ma Y, Luo B, et al. Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice. Aging Cell. 2019;18:e12961 pubmed 出版商

Li X, Ji Y, Song R, Li X, Guo L. KIF23 Promotes Gastric Cancer by Stimulating Cell Proliferation. Dis Markers. 2019;2019:9751923 pubmed 出版商

Wang G, Liu X, Xie J, Meng J, Ni X. PDK-1 mediated Hippo-YAP-IRS2 signaling pathway and involved in the apoptosis of non-small cell lung cancer cells. Biosci Rep. 2019;39: pubmed 出版商

Denu R, Sass M, Johnson J, Potts G, Choudhary A, Coon J, et al. Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131). J Biol Chem. 2019;294:6531-6549 pubmed 出版商

Rezuchova I, Hudecova S, Soltysova A, Matuskova M, Durinikova E, Chovancova B, et al. Type 3 inositol 1,4,5-trisphosphate receptor has antiapoptotic and proliferative role in cancer cells. Cell Death Dis. 2019;10:186 pubmed 出版商

Mehto S, Jena K, Nath P, Chauhan S, Kolapalli S, Das S, et al. The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. Mol Cell. 2019;73:429-445.e7 pubmed 出版商

Choi Y, Halbritter J, Braun D, Schueler M, Schapiro D, Rim J, et al. Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy. Am J Hum Genet. 2019;104:45-54 pubmed 出版商

Tay K, Flavell C, Cassini L, Wimber M, Lee J. Postretrieval Relearning Strengthens Hippocampal Memories via Destabilization and Reconsolidation. J Neurosci. 2019;39:1109-1118 pubmed 出版商

Polak R, Bierings M, van der Leije C, Sanders M, Roovers O, Marchante J, et al. Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1-driven B-cell precursor acute lymphoblastic leukemia. Haematologica. 2019;104:738-748 pubmed 出版商

Harrison I, Powell N, Dexter D. The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease. J Neurochem. 2019;148:136-156 pubmed 出版商

Zhang M, Urabe G, Little C, Wang B, Kent A, Huang Y, et al. HDAC6 Regulates the MRTF-A/SRF Axis and Vascular Smooth Muscle Cell Plasticity. JACC Basic Transl Sci. 2018;3:782-795 pubmed 出版商

Salissou M, Mahaman Y, Zhu F, Huang F, Wang Y, Xu Z, et al. Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats. Aging (Albany NY). 2018;10:3229-3248 pubmed 出版商

Wang X, Li R, Zacharek A, Landschoot Ward J, Wang F, Wu K, et al. Administration of Downstream ApoE Attenuates the Adverse Effect of Brain ABCA1 Deficiency on Stroke. Int J Mol Sci. 2018;19: pubmed 出版商

Xie G, Wang X, Jiang R, Zhao A, Yan J, Zheng X, et al. Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure. EBioMedicine. 2018;37:294-306 pubmed 出版商

Meng M, Li L, Li R, Wang W, Chen Y, Xie Y, et al. A dynamic transcriptomic atlas of cytokine-induced killer cells. J Biol Chem. 2018;293:19600-19612 pubmed 出版商

Lindeløv Vestergaard A, Heiner Bang Berthelsen C, Fløyel T, Lucien Stahl J, Christen L, Taheri Sotudeh F, et al. MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage. PLoS ONE. 2018;13:e0203713 pubmed 出版商

Richardson R, Ohlson M, Eitson J, Kumar A, McDougal M, Boys I, et al. A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication. Nat Microbiol. 2018;3:1214-1223 pubmed 出版商

Mar K, Rinkenberger N, Boys I, Eitson J, McDougal M, Richardson R, et al. LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step. Nat Commun. 2018;9:3603 pubmed 出版商

Young P, Senkal C, Suchanek A, Grevengoed T, Lin D, Zhao L, et al. Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways. J Biol Chem. 2018;293:16724-16740 pubmed 出版商

Fuqua B, Lu Y, Frazer D, Darshan D, Wilkins S, Dunn L, et al. Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin. Cell Mol Gastroenterol Hepatol. 2018;6:405-427 pubmed 出版商

Wohlgemuth N, Lane A, Pekosz A. Influenza A Virus M2 Protein Apical Targeting Is Required for Efficient Virus Replication. J Virol. 2018;92: pubmed 出版商

Huang Y, Chu P, Chen J, Huang C, Lee C, Lau K, et al. SET Overexpression is Associated with Worse Recurrence-Free Survival in Patients with Primary Breast Cancer Receiving Adjuvant Tamoxifen Treatment. J Clin Med. 2018;7: pubmed 出版商

Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed 出版商

Gagné A, Tetu B, Orain M, Turcotte S, Plante M, Gregoire J, et al. HtrA1 expression and the prognosis of high-grade serous ovarian carcinoma: a cohort study using digital analysis. Diagn Pathol. 2018;13:57 pubmed 出版商

Aichem A, Anders S, Catone N, Rößler P, Stotz S, Berg A, et al. The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation. Nat Commun. 2018;9:3321 pubmed 出版商

Chen X, Legrand A, Cunniffe S, Hume S, Poletto M, Vaz B, et al. Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients. Cell Oncol (Dordr). 2018;41:527-539 pubmed 出版商

Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, et al. A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B. Sci Rep. 2018;8:11653 pubmed 出版商

Kuroda M, Ueda K, Kioka N. Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells. Sci Rep. 2018;8:11581 pubmed 出版商

Aranda C, Ocón B, Arredondo Amador M, Suárez M, Zarzuelo A, Chazin W, et al. Calprotectin protects against experimental colonic inflammation in mice. Br J Pharmacol. 2018;175:3797-3812 pubmed 出版商

Kiso M, Tanaka S, Saji S, Toi M, Sato F. Long isoform of VEGF stimulates cell migration of breast cancer by filopodia formation via NRP1/ARHGAP17/Cdc42 regulatory network. Int J Cancer. 2018;143:2905-2918 pubmed 出版商

Xiao J, Egger M, McMasters K, Hao H. Differential expression of ABCB5 in BRAF inhibitor-resistant melanoma cell lines. BMC Cancer. 2018;18:675 pubmed 出版商

Majd S, Power J, Chataway T, Grantham H. A comparison of LKB1/AMPK/mTOR metabolic axis response to global ischaemia in brain, heart, liver and kidney in a rat model of cardiac arrest. BMC Cell Biol. 2018;19:7 pubmed 出版商

El Badawy A, Ghoneim N, Nasr M, Elkhenany H, Ahmed T, Ahmed S, et al. Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells. Biol Open. 2018;7: pubmed 出版商

Hooper M, Wang J, Browning R, Ash J. Damage-associated molecular pattern recognition is required for induction of retinal neuroprotective pathways in a sex-dependent manner. Sci Rep. 2018;8:9115 pubmed 出版商

Marcassa E, Kallinos A, Jardine J, Rusilowicz Jones E, Martinez A, Kuehl S, et al. Dual role of USP30 in controlling basal pexophagy and mitophagy. EMBO Rep. 2018;19: pubmed 出版商

Hong H, An O, Chan T, Ng V, Kwok H, Lin J, et al. Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer. Nucleic Acids Res. 2018;46:7953-7969 pubmed 出版商

Heinzmann K, Nguyen Q, Honess D, Smith D, Stribbling S, Brickute D, et al. Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using 18F-ICMT-11 and 18F-FLT PET. J Nucl Med. 2018;59:1558-1565 pubmed 出版商

Xue M, Fu F, Ma Y, Zhang X, Li L, Feng L, et al. The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production. J Virol. 2018;92: pubmed 出版商

Bailey R, Armao D, Nagabhushan Kalburgi S, Gray S. Development of Intrathecal AAV9 Gene Therapy for Giant Axonal Neuropathy. Mol Ther Methods Clin Dev. 2018;9:160-171 pubmed 出版商

Wu R, Zeng J, Yuan J, Deng X, Huang Y, Chen L, et al. MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation. J Clin Invest. 2018;128:2551-2568 pubmed 出版商

Koh S, Wallez Y, Dunlop C, Bernaldo de Quirós Fernández S, Bapiro T, Richards F, et al. Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine. Cancer Res. 2018;78:3054-3066 pubmed 出版商

Miao J, Ying B, Li R, Tollefson A, Spencer J, Wold W, et al. Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9. Viruses. 2018;10: pubmed 出版商

Itou J, Li W, Ito S, Tanaka S, Matsumoto Y, Sato F, et al. Sal-like 4 protein levels in breast cancer cells are post-translationally down-regulated by tripartite motif-containing 21. J Biol Chem. 2018;293:6556-6564 pubmed 出版商

Sultan C, Saackel A, Stank A, Fleming T, Fedorova M, Hoffmann R, et al. Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol. 2018;16:113-122 pubmed 出版商

Willis A, Indra R, Wohak L, Sozeri O, Feser K, Mrízová I, et al. The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. Toxicology. 2018;398-399:1-12 pubmed 出版商

Sengiku A, Ueda M, Kono J, Sano T, Nishikawa N, Kunisue S, et al. Circadian coordination of ATP release in the urothelium via connexin43 hemichannels. Sci Rep. 2018;8:1996 pubmed 出版商

Matsumoto Y, Itou J, Sato F, Toi M. SALL4 - KHDRBS3 network enhances stemness by modulating CD44 splicing in basal-like breast cancer. Cancer Med. 2018;7:454-462 pubmed 出版商

Freeman S, Vega A, Riedl M, Collins R, Ostrowski P, Woods E, et al. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell. 2018;172:305-317.e10 pubmed 出版商

Jana M, Ghosh S, Pahan K. Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018;43:407-419 pubmed 出版商

Runtz L, Girard B, Toussenot M, Espallergues J, Fayd Herbe De Maudave A, Milman A, et al. Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures. Epilepsia. 2018;59:123-134 pubmed 出版商

Khorsandi S, Taanman J, Heaton N. Subunit composition of respiratory chain complex 1 and its responses to oxygen in mitochondria from human donor livers. BMC Res Notes. 2017;10:547 pubmed 出版商

Mlcochova P, Caswell S, Taylor I, Towers G, Gupta R. DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages. EMBO J. 2018;37:50-62 pubmed 出版商

Yee D, Shah K, Coles M, Sharp T, Lagos D. MicroRNA-155 induction via TNF-? and IFN-? suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells. J Biol Chem. 2017;292:20683-20693 pubmed 出版商

Liu H, Grantham M, Pekosz A. Mutations in the Influenza A Virus M1 Protein Enhance Virus Budding To Complement Lethal Mutations in the M2 Cytoplasmic Tail. J Virol. 2018;92: pubmed 出版商

Turnbull A, Ioannidis S, Krajewski W, Pinto Fernandez A, Heride C, Martin A, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017;550:481-486 pubmed 出版商

Periyasamy M, Singh A, Gemma C, Kranjec C, Farzan R, Leach D, et al. p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells. Nucleic Acids Res. 2017;45:11056-11069 pubmed 出版商

Garcia Gomez A, Li T, Kerick M, Català Moll F, Comet N, Rodriguez Ubreva J, et al. TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells. Nucleic Acids Res. 2017;45:10002-10017 pubmed 出版商

Chucair Elliott A, Gurung H, Carr M, Carr D. Colony Stimulating Factor-1 Receptor Expressing Cells Infiltrating the Cornea Control Corneal Nerve Degeneration in Response to HSV-1 Infection. Invest Ophthalmol Vis Sci. 2017;58:4670-4682 pubmed 出版商

Mass E, Jacome Galarza C, Blank T, Lazarov T, Durham B, Ozkaya N, et al. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature. 2017;549:389-393 pubmed 出版商

Yan Y, Xu T, Harikumar K, Miller L, Melcher K, Xu H. Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the ?-secretase cleavage sites. J Biol Chem. 2017;292:15826-15837 pubmed 出版商

Zhao Z, Tang K, Muylaert I, Samuelsson T, Elias P. CDK9 and SPT5 proteins are specifically required for expression of herpes simplex virus 1 replication-dependent late genes. J Biol Chem. 2017;292:15489-15500 pubmed 出版商

Boussadia B, Lakhal L, Payrastre L, Ghosh C, Pascussi J, Gangarossa G, et al. Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity. Neuroscience. 2018;370:130-138 pubmed 出版商

Bernier M, Catazaro J, Singh N, Wnorowski A, Boguszewska Czubara A, Jozwiak K, et al. GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts. Int J Cancer. 2017;141:2131-2142 pubmed 出版商

Su E, Cao C, Fredriksson L, Nilsson I, Stefanitsch C, Stevenson T, et al. Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke. Acta Neuropathol. 2017;134:585-604 pubmed 出版商

Goetze R, Kim D, Schinazi R, Kim B. A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells. J Biol Chem. 2017;292:14016-14025 pubmed 出版商

Gotsbacher M, Cho S, Kwon H, Karuso P. Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans. Proteome Sci. 2016;15:16 pubmed 出版商

COATES M, Brookes D, Kim Y, Allen H, Fordyce E, Meals E, et al. Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor. Antimicrob Agents Chemother. 2017;61: pubmed 出版商

Steinberg S, Gudmundsdottir S, Sveinbjörnsson G, Suvisaari J, Paunio T, Torniainen Holm M, et al. Truncating mutations in RBM12 are associated with psychosis. Nat Genet. 2017;49:1251-1254 pubmed 出版商

Bourgeois C, Satou R, Prieto M. HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference. Biol Sex Differ. 2017;8:18 pubmed 出版商

Friis S, Tadeo D, Le Gall S, Jürgensen H, Sales K, Camerer E, et al. Matriptase zymogen supports epithelial development, homeostasis and regeneration. BMC Biol. 2017;15:46 pubmed 出版商

Yanagisawa S, Baker J, Vuppusetty C, Fenwick P, Donnelly L, Ito K, et al. Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD. Am J Physiol Lung Cell Mol Physiol. 2017;313:L230-L239 pubmed 出版商

Wu Y, Feng J, Hu W, Zhang Y. T-box 3 overexpression is associated with poor prognosis of non-small cell lung cancer. Oncol Lett. 2017;13:3335-3341 pubmed 出版商

Yanagisawa S, Papaioannou A, Papaporfyriou A, Baker J, Vuppusetty C, Loukides S, et al. Decreased Serum Sirtuin-1 in COPD. Chest. 2017;152:343-352 pubmed 出版商

Chen S, Li H, Zhang J, Jiang S, Zhang M, Xu Y, et al. Identification of Sp1 as a Transcription Activator to Regulate Fibroblast Growth Factor 21 Gene Expression. Biomed Res Int. 2017;2017:8402035 pubmed 出版商

Gomes L, Menck C, Cuervo A. Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation. Autophagy. 2017;13:928-940 pubmed 出版商

Starheim K, Kalvik T, Bjørkøy G, Arnesen T. Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization. Biosci Rep. 2017;37: pubmed 出版商

Wei J, Yang P, Li W, He F, Zeng S, Zhang T, et al. Gambogic acid potentiates the chemosensitivity of colorectal cancer cells to 5-fluorouracil by inhibiting proliferation and inducing apoptosis. Exp Ther Med. 2017;13:662-668 pubmed 出版商

Li Y, Zhu H, Wei X, Li H, Yu Z, Zhang H, et al. LPS induces HUVEC angiogenesis in vitro through miR-146a-mediated TGF-?1 inhibition. Am J Transl Res. 2017;9:591-600 pubmed

Setty B, Pillay Smiley N, Pool C, Jin Y, Liu Y, Nelin L. Hypoxia-induced proliferation of HeLa cells depends on epidermal growth factor receptor-mediated arginase II induction. Physiol Rep. 2017;5: pubmed 出版商

Peng X, Studholme K, Kanjiya M, Luk J, Bogdan D, Elmes M, et al. Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms. Mol Pain. 2017;13:1744806917697007 pubmed 出版商

Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma. World J Gastroenterol. 2017;23:1568-1575 pubmed 出版商

Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017;36:1243-1260 pubmed 出版商

Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed 出版商

Zhu Y, Kawaguchi K, Kiyama R. Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors. PLoS ONE. 2017;12:e0171390 pubmed 出版商

Chen R, Li X, He B, Hu W. MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma. Mol Med Rep. 2017;15:1326-1334 pubmed 出版商

Colomer Lluch M, Serra Moreno R. BCA2/Rabring7 Interferes with HIV-1 Proviral Transcription by Enhancing the SUMOylation of IκBα. J Virol. 2017;91: pubmed 出版商

Mlcochova P, Sutherland K, Watters S, Bertoli C, de Bruin R, Rehwinkel J, et al. A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages. EMBO J. 2017;36:604-616 pubmed 出版商

Biever A, Boubaker Vitre J, Cutando L, Gracia Rubio I, Costa Mattioli M, Puighermanal E, et al. Repeated Exposure to D-Amphetamine Decreases Global Protein Synthesis and Regulates the Translation of a Subset of mRNAs in the Striatum. Front Mol Neurosci. 2016;9:165 pubmed 出版商

Serrano Pozo A, Sánchez García M, Heras Garvín A, March Díaz R, Navarro V, Vizuete M, et al. Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo. PLoS ONE. 2017;12:e0170345 pubmed 出版商

Guo Y, Shan B, Guo W, Dong Z, Zhou Z, Shen S, et al. Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma. J Biomed Sci. 2017;24:6 pubmed 出版商

Zhang X, Liu Z, Chen M, Cao Q, Huang D. Effects of S100A6 gene silencing on the biological features of eutopic endometrial stromal cells and ??catenin expression. Mol Med Rep. 2017;15:1279-1285 pubmed 出版商

Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, et al. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Res. 2017;45:3738-3751 pubmed 出版商

Anantharaman A, Tripathi V, Khan A, Yoon J, Singh D, Gholamalamdari O, et al. ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins. Nucleic Acids Res. 2017;45:4189-4201 pubmed 出版商

Bademosi A, Lauwers E, Padmanabhan P, Odierna L, Chai Y, Papadopulos A, et al. In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters. Nat Commun. 2017;8:13660 pubmed 出版商

Li C, Liu S, Yan R, Han N, WONG K, Li L. CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer. Theranostics. 2017;7:67-80 pubmed 出版商

Askew E, Bai S, Parris A, Minges J, Wilson E. Androgen receptor regulation by histone methyltransferase Suppressor of variegation 3-9 homolog 2 and Melanoma antigen-A11. Mol Cell Endocrinol. 2017;443:42-51 pubmed 出版商

Li Y, Buijs Gladdines J, Cant Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed 出版商

Fletcher C, Godfrey J, Shibakawa A, Bushell M, Bevan C. A novel role for GSK3? as a modulator of Drosha microprocessor activity and MicroRNA biogenesis. Nucleic Acids Res. 2016;: pubmed

Sacilotto N, Chouliaras K, Nikitenko L, Lu Y, Fritzsche M, Wallace M, et al. MEF2 transcription factors are key regulators of sprouting angiogenesis. Genes Dev. 2016;30:2297-2309 pubmed

Zhu Z, Song W, Zhang C, Yin J. Dimethyloxaloylglycine increases bone repair capacity of adipose-derived stem cells in the treatment of osteonecrosis of the femoral head. Exp Ther Med. 2016;12:2843-2850 pubmed

Wang Y, He T, Liu J, Liu H, Zhou L, Hao W, et al. Synergistic effects of overexpression of BMP?2 and TGF??3 on osteogenic differentiation of bone marrow mesenchymal stem cells. Mol Med Rep. 2016;14:5514-5520 pubmed 出版商

Melo T, van Zomeren K, Ferrari M, Boddeke H, Copray J. Impairment of mitochondria dynamics by human A53T ?-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease. Exp Brain Res. 2017;235:731-742 pubmed 出版商

Wang C, Zhang W, Zhang L, Chen X, Liu F, Zhang J, et al. miR-146a-5p mediates epithelial-mesenchymal transition of oesophageal squamous cell carcinoma via targeting Notch2. Br J Cancer. 2016;115:1548-1554 pubmed 出版商

Mehta A, Cordero J, Dobersch S, Romero Olmedo A, Savai R, Bodner J, et al. Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate. EMBO Mol Med. 2016;8:1380-1389 pubmed 出版商

Prokesch A, Graef F, Madl T, Kahlhofer J, Heidenreich S, Schümann A, et al. Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis. FASEB J. 2017;31:732-742 pubmed 出版商

Hirschmugl B, Desoye G, Catalano P, Klymiuk I, Scharnagl H, Payr S, et al. Maternal obesity modulates intracellular lipid turnover in the human term placenta. Int J Obes (Lond). 2017;41:317-323 pubmed 出版商

García Mariscal A, Peyrollier K, Basse A, Pedersen E, Ruhl R, van Hengel J, et al. RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism. Small Gtpases. 2018;9:433-444 pubmed 出版商

Xu M, Liu Q, Jia Y, Tu K, Yao Y, Liu Q, et al. BCAT1 promotes tumor cell migration and invasion in hepatocellular carcinoma. Oncol Lett. 2016;12:2648-2656 pubmed

Mahgoub M, Adachi M, Suzuki K, Liu X, Kavalali E, Chahrour M, et al. MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors. Nat Neurosci. 2016;19:1506-1512 pubmed 出版商

Sadick J, Boutin M, Hoffman Kim D, Darling E. Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations. Sci Rep. 2016;6:33999 pubmed 出版商

Kasula R, Chai Y, Bademosi A, Harper C, Gormal R, Morrow I, et al. The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming. J Cell Biol. 2016;214:847-58 pubmed 出版商

Heride C, Rigden D, Bertsoulaki E, Cucchi D, De Smaele E, Clague M, et al. The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability. J Cell Sci. 2016;129:4001-4013 pubmed

Miao R, Wu Y, Zhang H, Zhou H, Sun X, Csizmadia E, et al. Utility of the dual-specificity protein kinase TTK as a therapeutic target for intrahepatic spread of liver cancer. Sci Rep. 2016;6:33121 pubmed 出版商

Banuelos C, Tavakoli I, Tien A, Caley D, Mawji N, Li Z, et al. Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain. J Biol Chem. 2016;291:22231-22243 pubmed

Zhang X, Zhu C, Luo Q, Dong J, Liu L, Li M, et al. Impact of siRNA targeting of ?-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage. Mol Med Rep. 2016;14:3595-601 pubmed 出版商

Nguyen T, Quan X, Xu S, Das R, Cha S, Kong I, et al. Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion. FASEB J. 2016;30:3979-3988 pubmed

Bortnik S, Choutka C, Horlings H, Leung S, Baker J, Lebovitz C, et al. Identification of breast cancer cell subtypes sensitive to ATG4B inhibition. Oncotarget. 2016;7:66970-66988 pubmed 出版商

Moxley K, Wang L, Welm A, Bieniasz M. Short-form Ron is a novel determinant of ovarian cancer initiation and progression. Genes Cancer. 2016;7:169-81 pubmed 出版商

Mandriota S, Tenan M, Ferrari P, Sappino A. Aluminium chloride promotes tumorigenesis and metastasis in normal murine mammary gland epithelial cells. Int J Cancer. 2016;139:2781-2790 pubmed 出版商

Li Y, Cui S, Sun S, Shi W, Song Z, Wang S, et al. Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice. Oncotarget. 2016;7:60446-60460 pubmed 出版商

Xie W, Liu C, Wu D, Li Z, Li C, Zhang Y. Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas. Oncotarget. 2016;7:50883-50894 pubmed 出版商

Kim D, Chang M, Yoon C, Middeldorp J, Martinez O, Byeon S, et al. Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells. Oncotarget. 2016;7:82213-82227 pubmed 出版商

Coulson Thomas V, Lauer M, Soleman S, Zhao C, Hascall V, Day A, et al. Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury. J Biol Chem. 2016;291:19939-52 pubmed 出版商

Ocón B, Aranda C, Gámez Belmonte R, Suárez M, Zarzuelo A, Martinez Augustin O, et al. The glucocorticoid budesonide has protective and deleterious effects in experimental colitis in mice. Biochem Pharmacol. 2016;116:73-88 pubmed 出版商

Phan A, Hua T, Kim M, Vo V, Choi J, Kim H, et al. Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer. Oncotarget. 2016;7:54702-54713 pubmed 出版商

Chen B, Zheng B, DeRan M, Jarugumilli G, Fu J, Brooks Y, et al. ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity. Nat Chem Biol. 2016;12:686-93 pubmed 出版商

Kaliszczak M, Trousil S, Ali T, Aboagye E. AKT activation controls cell survival in response to HDAC6 inhibition. Cell Death Dis. 2016;7:e2286 pubmed 出版商

Hou X, Tian J, Geng J, Li X, Tang X, Zhang J, et al. MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy. Oncotarget. 2016;7:47760-47776 pubmed 出版商

Verboon L, Obulkasim A, de Rooij J, Katsman Kuipers J, Sonneveld E, Baruchel A, et al. MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia. Oncotarget. 2016;7:48412-48422 pubmed 出版商

Dobierzewska A, Palominos M, Sánchez M, Dyhr M, Helgert K, Venegas Araneda P, et al. Impairment of Angiogenic Sphingosine Kinase-1/Sphingosine-1-Phosphate Receptors Pathway in Preeclampsia. PLoS ONE. 2016;11:e0157221 pubmed 出版商

Zhang Z, Han Y, Wang C, Zhou C, Wu L, Zhang H, et al. The effect of subarachnoid erythrocyte lysate on brain injury: a preliminary study. Biosci Rep. 2016;36: pubmed 出版商

Trousil S, Kaliszczak M, Schug Z, Nguyen Q, Tomasi G, Favicchio R, et al. The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. Oncotarget. 2016;7:37103-37120 pubmed 出版商

Qin G, Chen Y, Li H, Xu S, Li Y, Sun J, et al. Melittin inhibits tumor angiogenesis modulated by endothelial progenitor cells associated with the SDF-1?/CXCR4 signaling pathway in a UMR-106 osteosarcoma xenograft mouse model. Mol Med Rep. 2016;14:57-68 pubmed 出版商

Cui S, Shi W, Song Z, Wang S, Yu X, Gao Z, et al. Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways. Oncotarget. 2016;7:36767-36782 pubmed 出版商

Wang W, Zhan M, Li Q, Chen W, Chu H, Huang Q, et al. FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression. Oncotarget. 2016;7:34617-29 pubmed 出版商

Kamranvar S, Gupta D, Huang Y, Gupta R, Johansson S. Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody. Oncotarget. 2016;7:30820-30 pubmed 出版商

Miura N, Kamita M, Kakuya T, Fujiwara Y, Tsuta K, Shiraishi H, et al. Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4. Oncotarget. 2016;7:33165-78 pubmed 出版商

Zhu L, Cheng X, Shi J, Jiacheng L, Chen G, Jin H, et al. Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis. Oncogene. 2016;35:5388-5399 pubmed 出版商

Fang Y, Guan X, Cai T, Long J, Wang H, Xie X, et al. Knockdown of ANXA1 suppresses the biological behavior of human NSCLC cells in vitro. Mol Med Rep. 2016;13:3858-66 pubmed 出版商

Yang S, Sun Y, Geng Z, Ma K, Sun X, Fu X. Abnormalities in the basement membrane structure promote basal keratinocytes in the epidermis of hypertrophic scars to adopt a proliferative phenotype. Int J Mol Med. 2016;37:1263-73 pubmed 出版商

Zhou Y, Gu P, Shi W, Li J, Hao Q, Cao X, et al. MicroRNA-29a induces insulin resistance by targeting PPARδ in skeletal muscle cells. Int J Mol Med. 2016;37:931-8 pubmed 出版商

Ma Y, Wang X, Peng Y, Ding X. Forkhead box O1 promotes INS‑1 cell apoptosis by reducing the expression of CD24. Mol Med Rep. 2016;13:2991-8 pubmed 出版商

Hoyne G, Rudnicka C, SANG Q, Roycik M, Howarth S, Leedman P, et al. Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer. BMC Cancer. 2016;16:151 pubmed 出版商

Lin S, Liu T, Ming X, Tang Z, Fu L, Schmitt Kopplin P, et al. Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions. Sci Rep. 2016;6:21184 pubmed 出版商

Wei J, Long L, Yang K, Guy C, Shrestha S, Chen Z, et al. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. Nat Immunol. 2016;17:277-85 pubmed 出版商

Poletto M, Legrand A, Fletcher S, Dianov G. p53 coordinates base excision repair to prevent genomic instability. Nucleic Acids Res. 2016;44:3165-75 pubmed 出版商

Wang L, Xu W, Cao L, Tian T, Yang M, Li Z, et al. Differential Expression of Proteins Associated with the Hair Follicle Cycle - Proteomics and Bioinformatics Analyses. PLoS ONE. 2016;11:e0146791 pubmed 出版商

Li J, Zhu S, Tong J, Hao H, Yang J, Liu Z, et al. Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma. Neuroreport. 2016;27:110-5 pubmed 出版商

Kailainathan S, Piers T, Yi J, Choi S, Fahey M, Borger E, et al. Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF). Pharmacol Res. 2016;104:97-107 pubmed 出版商

Holmer R, Wätzig G, Tiwari S, Rose John S, Kalthoff H. Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells. BMC Cancer. 2015;15:975 pubmed 出版商

Sun X, Qin H, Zhang Z, Xu Y, Yang X, Zhao D, et al. Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress‑induced apoptosis. Mol Med Rep. 2016;13:661-8 pubmed 出版商

Pettersen K, Monsen V, HakvÃ¥g Pettersen C, Overland H, Pettersen G, Samdal H, et al. DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2016;90:158-72 pubmed 出版商

Hou X, Adeosun S, Zhang Q, Barlow B, Brents M, Zheng B, et al. Differential contributions of ApoE4 and female sex to BACE1 activity and expression mediate Aβ deposition and learning and memory in mouse models of Alzheimer's disease. Front Aging Neurosci. 2015;7:207 pubmed 出版商

Choi S, Pang K, Kim J, Ryu J, Kang H, Liu Z, et al. Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders. Mol Brain. 2015;8:74 pubmed 出版商

Corbett L, Mann J, Mann D. Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells. PLoS ONE. 2015;10:e0142794 pubmed 出版商

Schaefer Klein J, Murphy S, Johnson S, Vasmatzis G, Kovtun I. Topoisomerase 2 Alpha Cooperates with Androgen Receptor to Contribute to Prostate Cancer Progression. PLoS ONE. 2015;10:e0142327 pubmed 出版商

Bai A, Moss A, Rothweiler S, Serena Longhi M, Wu Y, Junger W, et al. NADH oxidase-dependent CD39 expression by CD8(+) T cells modulates interferon gamma responses via generation of adenosine. Nat Commun. 2015;6:8819 pubmed 出版商

Jiang Y, Wang L. Role of histone deacetylase 3 in ankylosing spondylitis via negative feedback loop with microRNA-130a and enhancement of tumor necrosis factor-1α expression in peripheral blood mononuclear cells. Mol Med Rep. 2016;13:35-40 pubmed 出版商

Yu Y, Cai Z, Cui M, Nie P, Sun Z, Sun S, et al. The orphan nuclear receptor Nur77 inhibits low shear stress-induced carotid artery remodeling in mice. Int J Mol Med. 2015;36:1547-55 pubmed 出版商

Jeon Y, Na H, Ryu H, Chung Y. Modulation of Dendritic Cell Activation and Subsequent Th1 Cell Polarization by Lidocaine. PLoS ONE. 2015;10:e0139845 pubmed 出版商

Li Y, Saini P, Sriraman A, Dobbelstein M. Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors. Oncotarget. 2015;6:32339-52 pubmed 出版商

Neumann Z, Pondenis H, Masyr A, Byrum M, Wycislo K, Fan T. The Association of Endothelin-1 Signaling with Bone Alkaline Phosphatase Expression and Protumorigenic Activities in Canine Osteosarcoma. J Vet Intern Med. 2015;29:1584-94 pubmed 出版商

Herold S, Kumar P, Wichert S, Kretzschmar B, Bähr M, Rossner M, et al. Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53. PLoS ONE. 2015;10:e0138852 pubmed 出版商

Shelton L, Lister A, Walsh J, Jenkins R, Wong M, Rowe C, et al. Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney Int. 2015;88:1261-1273 pubmed 出版商

Park J, Jeong S. Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells. Oncotarget. 2015;6:34658-68 pubmed 出版商

Kramer H, Lai C, Patel H, Periyasamy M, Lin M, Feller S, et al. LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. Nucleic Acids Res. 2016;44:582-94 pubmed 出版商

Do M, Shimizu N, Suzuki T, Ohtsubo H, Mizunoya W, Nakamura M, et al. Transmembrane proteoglycans syndecan-2, 4, receptor candidates for the impact of HGF and FGF2 on semaphorin 3A expression in early-differentiated myoblasts. Physiol Rep. 2015;3: pubmed 出版商

Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed 出版商

Sui X, Zhu J, Tang H, Wang C, Zhou J, Han W, et al. p53 controls colorectal cancer cell invasion by inhibiting the NF-κB-mediated activation of Fascin. Oncotarget. 2015;6:22869-79 pubmed

Tripathy D, Choudhary A, Banerjee U, Singh I, Chatterjee A. Induction of Apoptosis and Reduction of Endogenous Glutathione Level by the Ethyl-Acetate Soluble Fraction of the Methanol Extract of the Roots of Potentilla fulgens in Cancer Cells. PLoS ONE. 2015;10:e0135890 pubmed 出版商

Nishina K, Piao W, Yoshida Tanaka K, Sujino Y, Nishina T, Yamamoto T, et al. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. Nat Commun. 2015;6:7969 pubmed 出版商

Chin Smith E, Willey F, Slater D, Taggart M, Tribe R. Nuclear factor of activated T-cell isoform expression and regulation in human myometrium. Reprod Biol Endocrinol. 2015;13:83 pubmed 出版商

Carter M, Jemth A, Hagenkort A, Page B, Gustafsson R, Griese J, et al. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun. 2015;6:7871 pubmed 出版商

Lu H, Gao Z, Zhao Z, Weng J, Ye J. Transient hypoxia reprograms differentiating adipocytes for enhanced insulin sensitivity and triglyceride accumulation. Int J Obes (Lond). 2016;40:121-8 pubmed 出版商

Kirscher L, Deán Ben X, Scadeng M, Zaremba A, Zhang Q, Kober C, et al. Doxycycline Inducible Melanogenic Vaccinia Virus as Theranostic Anti-Cancer Agent. Theranostics. 2015;5:1045-57 pubmed 出版商

Hartman W, Helan M, Smelter D, Sathish V, Thompson M, Pabelick C, et al. Role of Hypoxia-Induced Brain Derived Neurotrophic Factor in Human Pulmonary Artery Smooth Muscle. PLoS ONE. 2015;10:e0129489 pubmed 出版商

Malik I, Stange I, Martius G, Cameron S, Rave Fränk M, Hess C, et al. Role of PECAM-1 in radiation-induced liver inflammation. J Cell Mol Med. 2015;19:2441-52 pubmed 出版商

Wheway G, Schmidts M, Mans D, Szymanska K, Nguyen T, Racher H, et al. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol. 2015;17:1074-1087 pubmed 出版商

Kober C, Rohn S, Weibel S, Geissinger U, Chen N, Szalay A. Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps. J Transl Med. 2015;13:216 pubmed 出版商

Chen L, Yang B, Zhou L, Ren F, Duan Z, Ma Y. Promotion of mitochondrial energy metabolism during hepatocyte apoptosis in a rat model of acute liver failure. Mol Med Rep. 2015;12:5035-41 pubmed 出版商

Fletcher A, Christensen D, NELSON C, Tan C, Schaller T, Lehner P, et al. TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription. EMBO J. 2015;34:2078-95 pubmed 出版商

Sanders D, Gormally M, Marsico G, Beraldi D, Tannahill D, Balasubramanian S. FOXM1 binds directly to non-consensus sequences in the human genome. Genome Biol. 2015;16:130 pubmed 出版商

Faronato M, Nguyen V, Patten D, Lombardo Y, Steel J, Patel N, et al. DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation. Oncotarget. 2015;6:22467-79 pubmed

Chen M, Yen C, Cheng C, Wu R, Huang S, Yu C, et al. Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. Oncotarget. 2015;6:23594-608 pubmed

Nahorski M, Al Gazali L, Hertecant J, Owen D, Borner G, Chen Y, et al. A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development. Brain. 2015;138:2147-60 pubmed 出版商

Harrison I, Crum W, Vernon A, Dexter D. Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors. Br J Pharmacol. 2015;172:4200-15 pubmed 出版商

Ke B, Zhao Z, Ye X, Gao Z, Manganiello V, Wu B, et al. Inactivation of NF-κB p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA Pathway. Diabetes. 2015;64:3355-62 pubmed 出版商

Wende C, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, et al. Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis. PLoS ONE. 2015;10:e0127681 pubmed 出版商

Sacco J, Kenyani J, Butt Z, Carter R, Chew H, Cheeseman L, et al. Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors. Oncotarget. 2015;6:13757-71 pubmed

Chabowska Kita A, Trabczynska A, Korytko A, Kaczmarek M, Kozak L. Low ambient temperature during early postnatal development fails to cause a permanent induction of brown adipocytes. FASEB J. 2015;29:3238-52 pubmed 出版商

Tang J, Cui W, Song F, Zhai C, Hu H, Zuo Q, et al. Effects of mesenchymal stem cells on interleukin-1β-treated chondrocytes and cartilage in a rat osteoarthritic model. Mol Med Rep. 2015;12:1753-60 pubmed 出版商

Tang Y, Jiang J, Wang S, Liu Z, Tang X, Peng J, et al. TLR4/NF-κB signaling contributes to chronic unpredictable mild stress-induced atherosclerosis in ApoE-/- mice. PLoS ONE. 2015;10:e0123685 pubmed 出版商

Boeddeker S, Baston Buest D, Fehm T, Kruessel J, Hess A. Decidualization and syndecan-1 knock down sensitize endometrial stromal cells to apoptosis induced by embryonic stimuli. PLoS ONE. 2015;10:e0121103 pubmed 出版商

Mazumdar S, Arendt L, Phillips S, Sedic M, Kuperwasser C, Gill G. CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer. PLoS ONE. 2015;10:e0121281 pubmed 出版商

Labouba I, Poisson A, Lafontaine J, Delvoye N, Gannon P, Le Page C, et al. The RelB alternative NF-kappaB subunit promotes autophagy in 22Rv1 prostate cancer cells in vitro and affects mouse xenograft tumor growth in vivo. Cancer Cell Int. 2014;14:67 pubmed 出版商

Dou X, Wei J, Sun A, Shao G, Childress C, Yang W, et al. PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation. Cancer Cell Int. 2015;15:27 pubmed 出版商

Rouhollahi E, Zorofchian Moghadamtousi S, Paydar M, Fadaeinasab M, Zahedifard M, Hajrezaie M, et al. Inhibitory effect of Curcuma purpurascens BI. rhizome on HT-29 colon cancer cells through mitochondrial-dependent apoptosis pathway. BMC Complement Altern Med. 2015;15:15 pubmed 出版商

Modelska A, Turro E, Russell R, Beaton J, Sbarrato T, Spriggs K, et al. The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape. Cell Death Dis. 2015;6:e1603 pubmed 出版商

Scheuplein V, Seifried J, Malczyk A, Miller L, Höcker L, Vergara Alert J, et al. High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus. J Virol. 2015;89:3859-69 pubmed 出版商

Kwak J, Son M, Son Y, Son M, Cho Y. Biochemical and molecular characterization of novel mutations in GLB1 and NEU1 in patient cells with lysosomal storage disorders. Biochem Biophys Res Commun. 2015;457:554-60 pubmed 出版商

Lee J, Choi D, Choi J, Kim S, Cho K, Lee J, et al. Methyl-β-cyclodextrin up-regulates collagen I expression in chronologically-aged skin via its anti-caveolin-1 activity. Oncotarget. 2015;6:1942-53 pubmed

Fan F, Geurts A, Murphy S, Pabbidi M, Jacob H, Roman R. Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. Am J Physiol Regul Integr Comp Physiol. 2015;308:R379-90 pubmed 出版商

Chu J, Gao Z, Qu X. Down-regulation of sphingosine kinase 2 (SphK2) increases the effects of all-trans-retinoic acid (ATRA) on colon cancer cells. Biomed Pharmacother. 2014;68:1089-97 pubmed 出版商

Darvas M, Palmiter R. Specific contributions of N-methyl-D-aspartate receptors in the dorsal striatum to cognitive flexibility. Neuroscience. 2015;284:934-42 pubmed 出版商

Cook G, Caudell D, Elford H, Pardee T. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML. PLoS ONE. 2014;9:e112619 pubmed 出版商

Fan F, Geurts A, Pabbidi M, Smith S, Harder D, Jacob H, et al. Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. PLoS ONE. 2014;9:e112878 pubmed 出版商

Lee M, Cheng M, Lin C, Louis E, Faust P, Kuo S. Decreased EAAT2 protein expression in the essential tremor cerebellar cortex. Acta Neuropathol Commun. 2014;2:157 pubmed 出版商

Gormally M, Dexheimer T, Marsico G, Sanders D, Lowe C, Matak Vinković D, et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014;5:5165 pubmed 出版商

Tang K, Norberg P, Holmudden M, Elias P, Liljeqvist J. Rad51 and Rad52 are involved in homologous recombination of replicating herpes simplex virus DNA. PLoS ONE. 2014;9:e111584 pubmed 出版商

Lee C, Zhan Q, Lezcano C, Frank M, Huang J, Larson A, et al. Nestin depletion induces melanoma matrix metalloproteinases and invasion. Lab Invest. 2014;94:1382-95 pubmed 出版商

Lavorgna A, Matsuoka M, Harhaj E. A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation. PLoS Pathog. 2014;10:e1004418 pubmed 出版商

Itou J, Tanaka S, Sato F, Akiyama R, Kawakami Y, Toi M. An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer. Biochim Biophys Acta. 2015;1853:27-40 pubmed 出版商

Wang H, Chen Y, Chen J, Zhang Z, Lao W, Li X, et al. Cell cycle regulation of DNA polymerase beta in rotenone-based Parkinson's disease models. PLoS ONE. 2014;9:e109697 pubmed 出版商

Lolicato F, Brouwers J, de Lest C, Wubbolts R, Aardema H, Priore P, et al. The cumulus cell layer protects the bovine maturing oocyte against fatty acid-induced lipotoxicity. Biol Reprod. 2015;92:16 pubmed 出版商

Muylaert I, Zhao Z, Elias P. UL52 primase interactions in the herpes simplex virus 1 helicase-primase are affected by antiviral compounds and mutations causing drug resistance. J Biol Chem. 2014;289:32583-92 pubmed 出版商

Bukong T, Momen Heravi F, Kodys K, Bala S, Szabo G. Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90. PLoS Pathog. 2014;10:e1004424 pubmed 出版商

Trousil S, Lee P, Pinato D, Ellis J, Dina R, Aboagye E, et al. Alterations of choline phospholipid metabolism in endometrial cancer are caused by choline kinase alpha overexpression and a hyperactivated deacylation pathway. Cancer Res. 2014;74:6867-77 pubmed 出版商

Li X, Fang E, Scheibye Knudsen M, Cui H, Qiu L, Li J, et al. Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis. Sci Rep. 2014;4:6434 pubmed 出版商

Li J, Li Y, Zhang P, Niu H, Shi Y. Nicotinic acid modulates intracellular calcium concentration and disassembles the cytoskeleton. Mol Med Rep. 2014;10:2805-10 pubmed 出版商

Sahin P, Sahin Z, Gungor Ordueri N, Donmez B, Celik Ozenci C. Inhibition of mammalian target of rapamycin signaling pathway decreases retinoic acid stimulated gene 8 expression in adult mouse testis. Fertil Steril. 2014;102:1482-1490.e3 pubmed 出版商

Lemak M, Voloshanenko O, Draguhn A, Egorov A. KATP channels modulate intrinsic firing activity of immature entorhinal cortex layer III neurons. Front Cell Neurosci. 2014;8:255 pubmed 出版商

Castañeda Arellano R, Feria Velasco A, Rivera Cervantes M. Activity increase in EpoR and Epo expression by intranasal recombinant human erythropoietin (rhEpo) administration in ischemic hippocampi of adult rats. Neurosci Lett. 2014;583:16-20 pubmed 出版商

Röhrborn D, Eckel J, Sell H. Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells. FEBS Lett. 2014;588:3870-7 pubmed 出版商

Lee Y, Lee J, Kim M. PI3K/Akt pathway regulates retinoic acid-induced Hox gene expression in F9 cells. Dev Growth Differ. 2014;56:518-25 pubmed 出版商

Perng Y, Campbell J, Lenschow D, Yu D. Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription. PLoS Pathog. 2014;10:e1004350 pubmed 出版商

Pardee T, Lee K, Luddy J, Maturo C, Rodriguez R, Isom S, et al. A phase I study of the first-in-class antimitochondrial metabolism agent, CPI-613, in patients with advanced hematologic malignancies. Clin Cancer Res. 2014;20:5255-64 pubmed 出版商

Kanamori Y, Murakami M, Matsui T, Funaba M. The regulation of hepcidin expression by serum treatment: requirements of the BMP response element and STAT- and AP-1-binding sites. Gene. 2014;551:119-26 pubmed 出版商

Yang Q, Wu Z, Hadden J, Odem M, Zuo Y, Crook R, et al. Persistent pain after spinal cord injury is maintained by primary afferent activity. J Neurosci. 2014;34:10765-9 pubmed 出版商

Tian X, Wang F, He C, Zhang L, Tan D, Reiter R, et al. Beneficial effects of melatonin on bovine oocytes maturation: a mechanistic approach. J Pineal Res. 2014;57:239-47 pubmed 出版商

Negoro T, Shimizu S, Narushima M, Banham A, Wakabayashi H, Takayanagi R, et al. Elevated receptor for activated C kinase 1 expression is involved in intracellular Ca2+ influx and potentially associated with compromised regulatory T cell function in patients with asthma. Clin Exp Allergy. 2014;44:1154-69 pubmed 出版商

Roy A, Modi K, Khasnavis S, Ghosh S, Watson R, Pahan K. Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. PLoS ONE. 2014;9:e101883 pubmed 出版商

Hartsink Segers S, Beaudoin J, Luijendijk M, Exalto C, Pieters R, den Boer M. PKC? and PKM? are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity. Leukemia. 2015;29:304-11 pubmed 出版商

Vitanza N, Zaky W, Blum R, Meyer J, Wang J, Bhatla T, et al. Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance. Pediatr Blood Cancer. 2014;61:1779-85 pubmed 出版商

Kong K, Lee J, Oh J, Lee Y, Kim M. Akt1 mediates the posterior Hoxc gene expression through epigenetic modifications in mouse embryonic fibroblasts. Biochim Biophys Acta. 2014;1839:793-9 pubmed 出版商

Xue X, Yu J, Sun D, Kong F, Qu X, Zou W, et al. Curcumin induces apoptosis in SGC-7901 gastric adenocarcinoma cells via regulation of mitochondrial signaling pathways. Asian Pac J Cancer Prev. 2014;15:3987-92 pubmed

Gits C, van Kuijk P, de Rijck J, Muskens N, Jonkers M, Van Ijcken W, et al. MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3?. BMC Cancer. 2014;14:429 pubmed 出版商

Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes R. Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells. Breast Cancer Res. 2014;16:R62 pubmed 出版商

Maffei R, Bulgarelli J, Fiorcari S, Martinelli S, Castelli I, Valenti V, et al. Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor. PLoS ONE. 2014;9:e98818 pubmed 出版商

Fuqua B, Lu Y, Darshan D, Frazer D, Wilkins S, Wolkow N, et al. The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice. PLoS ONE. 2014;9:e98792 pubmed 出版商

Raftery M, Lalwani P, Krautkrӓmer E, Peters T, Scharffetter Kochanek K, Krüger R, et al. ?2 integrin mediates hantavirus-induced release of neutrophil extracellular traps. J Exp Med. 2014;211:1485-97 pubmed 出版商

Rio P, Baños R, Lombardo A, Quintana Bustamante O, Alvarez L, Garate Z, et al. Targeted gene therapy and cell reprogramming in Fanconi anemia. EMBO Mol Med. 2014;6:835-48 pubmed 出版商

Kosakowska Cholody T, Lin J, Srideshikan S, Scheffer L, Tarasova N, Acharya J. HKH40A downregulates GRP78/BiP expression in cancer cells. Cell Death Dis. 2014;5:e1240 pubmed 出版商

Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. Deregulation of RB1 expression by loss of imprinting in human hepatocellular carcinoma. J Pathol. 2014;233:392-401 pubmed 出版商

Zecchini V, Madhu B, Russell R, Pértega Gomes N, Warren A, Gaude E, et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J. 2014;33:1365-82 pubmed 出版商

Sun C, Xu H, Yuan Y, Gao Z, Lou H, Qu X. Riccardin D, a macrocyclic bisbibenzy, inhibits human breast cancer growth through the suppression of telomerase activity. Basic Clin Pharmacol Toxicol. 2014;115:488-98 pubmed 出版商

Chen M, Chiang K, Cheng C, Huang S, Chen Y, Chen T, et al. Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma. Oncotarget. 2014;5:2372-89 pubmed

Tremoen N, Fowler P, Ropstad E, Verhaegen S, Krogenæs A. Exposure to the three structurally different PCB congeners (PCB 118, 153, and 126) results in decreased protein expression and altered steroidogenesis in the human adrenocortical carcinoma cell line H295R. J Toxicol Environ Health A. 2014;77:516-34 pubmed 出版商

Wairagu P, Park K, Kim J, Choi J, Kim H, Yeh B, et al. Combined therapeutic potential of nuclear receptors with receptor tyrosine kinase inhibitors in lung cancer. Biochem Biophys Res Commun. 2014;447:490-5 pubmed 出版商

Wang F, Tian X, Zhang L, Gao C, He C, Fu Y, et al. Beneficial effects of melatonin on in vitro bovine embryonic development are mediated by melatonin receptor 1. J Pineal Res. 2014;56:333-42 pubmed 出版商

Nojiri S, Joh T. Albumin suppresses human hepatocellular carcinoma proliferation and the cell cycle. Int J Mol Sci. 2014;15:5163-74 pubmed 出版商

Stimpson K, Sullivan L, Kuo M, Sullivan B. Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS ONE. 2014;9:e92432 pubmed 出版商

Kooistra S, Nørgaard L, Lees M, Steinhauer C, Johansen J, Helin K. A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence. PLoS ONE. 2014;9:e91034 pubmed 出版商

Beaudry J, Dunford E, Teich T, Zaharieva D, Hunt H, Belanoff J, et al. Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats. PLoS ONE. 2014;9:e91248 pubmed 出版商

Ariës I, Jerchel I, van den Dungen R, van den Berk L, Boer J, Horstmann M, et al. EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion. Leukemia. 2014;28:1828-37 pubmed 出版商

Velten M, Gorr M, Youtz D, Velten C, Rogers L, Wold L. Adverse perinatal environment contributes to altered cardiac development and function. Am J Physiol Heart Circ Physiol. 2014;306:H1334-40 pubmed 出版商

Roy M, Mukherjee S. Reversal of resistance towards cisplatin by curcumin in cervical cancer cells. Asian Pac J Cancer Prev. 2014;15:1403-10 pubmed

Voloshyna I, Seshadri S, Anwar K, Littlefield M, Belilos E, Carsons S, et al. Infliximab reverses suppression of cholesterol efflux proteins by TNF-?: a possible mechanism for modulation of atherogenesis. Biomed Res Int. 2014;2014:312647 pubmed 出版商

Werner H, Trovik J, Halle M, Wik E, Akslen L, Birkeland E, et al. Stathmin protein level, a potential predictive marker for taxane treatment response in endometrial cancer. PLoS ONE. 2014;9:e90141 pubmed 出版商

Chu J, Zhao C, Song Z, Wang R, Qin Y, Li W, et al. 1082-39, an analogue of sorafenib, inhibited human cancer cell growth more potently than sorafenib. Biomed Pharmacother. 2014;68:335-41 pubmed 出版商

McNeill A, Magalhães J, Shen C, Chau K, Hughes D, Mehta A, et al. Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. Brain. 2014;137:1481-95 pubmed 出版商

Jiménez J, Prasad V, Yu M, Kampmeyer C, Kaakour A, Wang P, et al. Macro- and microscale variables regulate stent haemodynamics, fibrin deposition and thrombomodulin expression. J R Soc Interface. 2014;11:20131079 pubmed 出版商

Murakami Tonami Y, Kishida S, Takeuchi I, Katou Y, Maris J, Ichikawa H, et al. Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells. Cell Cycle. 2014;13:1115-31 pubmed 出版商

Hrdlicková R, Nehyba J, Bargmann W, Bose H. Multiple tumor suppressor microRNAs regulate telomerase and TCF7, an important transcriptional regulator of the Wnt pathway. PLoS ONE. 2014;9:e86990 pubmed 出版商

Boeddeker S, Baston Buest D, Altergot Ahmad O, Kruessel J, Hess A. Syndecan-1 knockdown in endometrial epithelial cells alters their apoptotic protein profile and enhances the inducibility of apoptosis. Mol Hum Reprod. 2014;20:567-78 pubmed 出版商

Prause M, Christensen D, Billestrup N, Mandrup Poulsen T. JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis. PLoS ONE. 2014;9:e87067 pubmed 出版商

Fujita H, Aoki H, Ajioka I, Yamazaki M, Abe M, Oh Nishi A, et al. Detailed expression pattern of aldolase C (Aldoc) in the cerebellum, retina and other areas of the CNS studied in Aldoc-Venus knock-in mice. PLoS ONE. 2014;9:e86679 pubmed 出版商

Millán Uclés Á, Diaz Castro B, García Flores P, Baez A, Perez Simon J, Lopez Barneo J, et al. A conditional mouse mutant in the tumor suppressor SdhD gene unveils a link between p21(WAF1/Cip1) induction and mitochondrial dysfunction. PLoS ONE. 2014;9:e85528 pubmed 出版商

Baez A, Martin Antonio B, Piruat J, Barbado M, Prats C, Álvarez Laderas I, et al. Gene and miRNA expression profiles of hematopoietic progenitor cells vary depending on their origin. Biol Blood Marrow Transplant. 2014;20:630-9 pubmed 出版商

Velten M, Britt R, Heyob K, Tipple T, Rogers L. Maternal dietary docosahexaenoic acid supplementation attenuates fetal growth restriction and enhances pulmonary function in a newborn mouse model of perinatal inflammation. J Nutr. 2014;144:258-66 pubmed 出版商

Noda K, Akita H, Ogata M, Saji M. Paclitaxel-induced hyperalgesia modulates negative affective component of pain and NR1 receptor expression in the frontal cortex in rats. Neurosci Res. 2014;80:32-7 pubmed 出版商

Caffarelli N, Fehr A, Yu D. Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication. PLoS Pathog. 2013;9:e1003825 pubmed 出版商

Javaid S, Zhang J, Anderssen E, Black J, Wittner B, Tajima K, et al. Dynamic chromatin modification sustains epithelial-mesenchymal transition following inducible expression of Snail-1. Cell Rep. 2013;5:1679-89 pubmed 出版商

Verginelli F, Perin A, Dali R, Fung K, Lo R, Longatti P, et al. Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. Nat Commun. 2013;4:2956 pubmed 出版商

Krähling A, Alvarez L, Debowski K, Van Q, Gunkel M, Irsen S, et al. CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending. PLoS Genet. 2013;9:e1003960 pubmed 出版商

Fan F, Sun C, Maier K, Williams J, Pabbidi M, Didion S, et al. 20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels. PLoS ONE. 2013;8:e82482 pubmed 出版商

Adeosun S, Hou X, Zheng B, Stockmeier C, Ou X, Paul I, et al. Cognitive deficits and disruption of neurogenesis in a mouse model of apolipoprotein E4 domain interaction. J Biol Chem. 2014;289:2946-59 pubmed 出版商

Wang F, Tian X, Zhang L, He C, Ji P, Li Y, et al. Beneficial effect of resveratrol on bovine oocyte maturation and subsequent embryonic development after in vitro fertilization. Fertil Steril. 2014;101:577-86 pubmed 出版商

Bastiaans J, van Meurs J, van Holten Neelen C, Nagtzaam N, van Hagen P, Chambers R, et al. Thrombin induces epithelial-mesenchymal transition and collagen production by retinal pigment epithelial cells via autocrine PDGF-receptor signaling. Invest Ophthalmol Vis Sci. 2013;54:8306-14 pubmed 出版商

Robinson J, Hickey T, Warren A, Vowler S, Carroll T, Lamb A, et al. Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype. Oncogene. 2014;33:5666-74 pubmed 出版商

Sacco J, Yau T, Darling S, Patel V, Liu H, Urbé S, et al. The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells. Oncogene. 2014;33:4265-72 pubmed 出版商

Graf A, Haines K, Pierson C, Bolon B, Houston R, Velten M, et al. Perinatal inflammation results in decreased oligodendrocyte numbers in adulthood. Life Sci. 2014;94:164-71 pubmed 出版商

Elsen M, Raschke S, Tennagels N, Schwahn U, Jelenik T, Roden M, et al. BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells. Am J Physiol Cell Physiol. 2014;306:C431-40 pubmed 出版商

Schoggins J, MacDuff D, Imanaka N, Gainey M, Shrestha B, Eitson J, et al. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 2014;505:691-5 pubmed 出版商

Wang P, Su C, Li R, Wang H, Ren Y, Sun H, et al. Mechanisms and effects of curcumin on spatial learning and memory improvement in APPswe/PS1dE9 mice. J Neurosci Res. 2014;92:218-31 pubmed 出版商

Murphy K, Cottle L, Gysbers A, Cooper A, Halliday G. ATP13A2 (PARK9) protein levels are reduced in brain tissue of cases with Lewy bodies. Acta Neuropathol Commun. 2013;1:11 pubmed 出版商

Sun Z, Zhang Y, Zhang R, Qi X, Su B. Functional divergence of the rapidly evolving miR-513 subfamily in primates. BMC Evol Biol. 2013;13:255 pubmed 出版商

Lin Y, Chen Y, Cohen S, Cheng T. Identification of TSG101 functional domains and p21 loci required for TSG101-mediated p21 gene regulation. PLoS ONE. 2013;8:e79674 pubmed 出版商

Dowdle J, Mehta M, Kass E, Vuong B, Inagaki A, Egli D, et al. Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. PLoS Genet. 2013;9:e1003945 pubmed 出版商

Qin Y, Lu Y, Wang R, Li W, Qu X. SL1122-37, a novel derivative of sorafenib, has greater effects than sorafenib on the inhibition of human hepatocellular carcinoma (HCC) growth and prevention of angiogenesis. Biosci Trends. 2013;7:237-44 pubmed

Rasaiyaah J, Tan C, Fletcher A, Price A, Blondeau C, Hilditch L, et al. HIV-1 evades innate immune recognition through specific cofactor recruitment. Nature. 2013;503:402-405 pubmed 出版商

Liu S, Vaziri N. Role of PCSK9 and IDOL in the pathogenesis of acquired LDL receptor deficiency and hypercholesterolemia in nephrotic syndrome. Nephrol Dial Transplant. 2014;29:538-43 pubmed 出版商

Chieppa M, Perota A, Corona C, Grindatto A, Lagutina I, Vallino Costassa E, et al. Modeling amyotrophic lateral sclerosis in hSOD1 transgenic swine. Neurodegener Dis. 2014;13:246-54 pubmed 出版商

Bresson S, Conrad N. The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay. PLoS Genet. 2013;9:e1003893 pubmed 出版商

Aries I, Hansen B, Koch T, van den Dungen R, Evans W, Pieters R, et al. The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance. Haematologica. 2013;98:1905-11 pubmed 出版商

Parris T, Kovács A, Aziz L, Hajizadeh S, Nemes S, Semaan M, et al. Additive effect of the AZGP1, PIP, S100A8 and UBE2C molecular biomarkers improves outcome prediction in breast carcinoma. Int J Cancer. 2014;134:1617-29 pubmed 出版商

Sabharwal S, Waypa G, Marks J, Schumacker P. Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling. Biochem J. 2013;456:337-46 pubmed 出版商

Xu J, Morris L, Thapa A, Ma H, Michalakis S, Biel M, et al. cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function. J Neurosci. 2013;33:14939-48 pubmed 出版商

Mudaliar M, Haggart R, Miele G, Sellar G, Tan K, Goodlad J, et al. Comparative gene expression profiling identifies common molecular signatures of NF-?B activation in canine and human diffuse large B cell lymphoma (DLBCL). PLoS ONE. 2013;8:e72591 pubmed 出版商

Graham E, Woo K, Aalderink M, Fry S, Greenwood J, Glass M, et al. M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells. PLoS ONE. 2013;8:e72011 pubmed 出版商

Ottaviani S, Brooke G, O Hanlon Brown C, Waxman J, Ali S, Buluwela L. Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells. J Mol Endocrinol. 2013;51:301-12 pubmed 出版商

Colley S, Wintle L, Searles R, Russell V, Firman R, Smith S, et al. Loss of the nuclear receptor corepressor SLIRP compromises male fertility. PLoS ONE. 2013;8:e70700 pubmed 出版商

Freyer L, Nowotschin S, Pirity M, Baldini A, Morrow B. Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice. BMC Dev Biol. 2013;13:33 pubmed 出版商

Gits C, van Kuijk P, Jonkers M, Boersma A, van Ijcken W, Wozniak A, et al. MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours. Br J Cancer. 2013;109:1625-35 pubmed 出版商

Itou J, Matsumoto Y, Yoshikawa K, Toi M. Sal-like 4 (SALL4) suppresses CDH1 expression and maintains cell dispersion in basal-like breast cancer. FEBS Lett. 2013;587:3115-21 pubmed 出版商

Wu W, Yu X, Luo X, Yang S, Zheng D. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013;253:212-6 pubmed 出版商

de Brouwer A, Nabuurs S, Verhaart I, Oudakker A, Hordijk R, Yntema H, et al. A 3-base pair deletion, c.9711_9713del, in DMD results in intellectual disability without muscular dystrophy. Eur J Hum Genet. 2014;22:480-5 pubmed 出版商

Zell S, Schmitt R, Witting S, Kreipe H, Hussein K, Becker J. Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis. Nephron Extra. 2013;3:50-8 pubmed 出版商

Sanchez A, Tripathy D, Yin X, Luo J, Martinez J, Grammas P. Sunitinib enhances neuronal survival in vitro via NF-?B-mediated signaling and expression of cyclooxygenase-2 and inducible nitric oxide synthase. J Neuroinflammation. 2013;10:93 pubmed 出版商

Hoivik E, Witsoe S, Bergheim I, Xu Y, Jakobsson I, Tengholm A, et al. DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoforms. PLoS ONE. 2013;8:e67925 pubmed 出版商

Mikula M, Bomsztyk K, Goryca K, Chojnowski K, Ostrowski J. Heterogeneous nuclear ribonucleoprotein (HnRNP) K genome-wide binding survey reveals its role in regulating 3'-end RNA processing and transcription termination at the early growth response 1 (EGR1) gene through XRN2 exonuclease. J Biol Chem. 2013;288:24788-98 pubmed 出版商

Darr J, Klochendler A, Isaac S, Eden A. Loss of IGFBP7 expression and persistent AKT activation contribute to SMARCB1/Snf5-mediated tumorigenesis. Oncogene. 2014;33:3024-32 pubmed 出版商

Vuong L, Brobst D, Ivanovic I, Sherry D, Al Ubaidi M. p53 selectively regulates developmental apoptosis of rod photoreceptors. PLoS ONE. 2013;8:e67381 pubmed 出版商

Nishimoto Y, Nakagawa S, Hirose T, Okano H, Takao M, Shibata S, et al. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain. 2013;6:31 pubmed 出版商

Zhang J, Gao Z, Ye J. Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation. Biochim Biophys Acta. 2013;1832:1980-8 pubmed 出版商

Kurkalang S, Banerjee A, Ghoshal N, Dkhar H, Chatterjee A. Induction of chromosome instability and stomach cancer by altering the expression pattern of mitotic checkpoint genes in mice exposed to areca-nut. BMC Cancer. 2013;13:315 pubmed 出版商

Damola A, Legendre A, Ball S, Masters J, Williamson M. Function of mutant and wild-type plexinb1 in prostate cancer cells. Prostate. 2013;73:1326-35 pubmed 出版商

Beaudry J, D souza A, Teich T, Tsushima R, Riddell M. Exogenous glucocorticoids and a high-fat diet cause severe hyperglycemia and hyperinsulinemia and limit islet glucose responsiveness in young male Sprague-Dawley rats. Endocrinology. 2013;154:3197-208 pubmed 出版商

Mandal P, Bhattacharjee B, Das Ghosh D, Mondal N, Roy Chowdhury R, Roy S, et al. Differential expression of HPV16 L2 gene in cervical cancers harboring episomal HPV16 genomes: influence of synonymous and non-coding region variations. PLoS ONE. 2013;8:e65647 pubmed 出版商

Kelly K, Liu Y, Zhang J, Goswami C, Lin H, Dominguez J. Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways. Physiol Genomics. 2013;45:710-9 pubmed 出版商

Zhang N, Wei X, Xu L. miR-150 promotes the proliferation of lung cancer cells by targeting P53. FEBS Lett. 2013;587:2346-51 pubmed 出版商

Lee J, Piao M, Choi J, Yun S, Lee J, Lee S. Up-regulation of cyclooxygenase 2 and matrix metalloproteinases-2 and -9 in cutaneous squamous cell carcinoma: active role of inflammation and tissue remodeling in carcinogenesis. Ann Dermatol. 2013;25:145-51 pubmed 出版商

Faronato M, Patel V, Darling S, Dearden L, Clague M, Urbé S, et al. The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit. Cell Cycle. 2013;12:1964-77 pubmed 出版商

Schlehe J, Journel M, Taylor K, Amodeo K, LaVoie M. The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress. Neurobiol Dis. 2013;58:57-67 pubmed 出版商

Famulla S, Schlich R, Sell H, Eckel J. Differentiation of human adipocytes at physiological oxygen levels results in increased adiponectin secretion and isoproterenol-stimulated lipolysis. Adipocyte. 2012;1:132-181 pubmed

Burgstaller G, Oehrle B, Koch I, Lindner M, Eickelberg O. Multiplex profiling of cellular invasion in 3D cell culture models. PLoS ONE. 2013;8:e63121 pubmed 出版商

Merz K, Lie D. Evidence that Doublecortin is dispensable for the development of adult born neurons in mice. PLoS ONE. 2013;8:e62693 pubmed 出版商

Baek I, Kim T, Seo J, Lee K, Lee Y, Cho J, et al. AAD-2004 Attenuates Progressive Neuronal Loss in the Brain of Tg-betaCTF99/B6 Mouse Model of Alzheimer Disease. Exp Neurobiol. 2013;22:31-7 pubmed 出版商

Bian S, Sun X, Bai A, Zhang C, Li L, Enjyoji K, et al. P2X7 integrates PI3K/AKT and AMPK-PRAS40-mTOR signaling pathways to mediate tumor cell death. PLoS ONE. 2013;8:e60184 pubmed 出版商

Nishikawa N, Kanematsu A, Negoro H, Imamura M, Sugino Y, Okinami T, et al. PTHrP is endogenous relaxant for spontaneous smooth muscle contraction in urinary bladder of female rat. Endocrinology. 2013;154:2058-68 pubmed 出版商

Kim Y, Zerin T, Song H. Antioxidant action of ellagic acid ameliorates paraquat-induced A549 cytotoxicity. Biol Pharm Bull. 2013;36:609-15 pubmed

Hirsch B, von der Wall E, Hummel M, Dürkop H. RIP1 expression is necessary for CD30-mediated cell death induction in anaplastic large-cell lymphoma cells. Lab Invest. 2013;93:677-89 pubmed 出版商

Elouarrat D, van der Velden Y, Jones D, Moolenaar W, Divecha N, Haramis A. Role of phosphatidylinositol 5-phosphate 4-kinase ? in zebrafish development. Int J Biochem Cell Biol. 2013;45:1293-301 pubmed 出版商

Philippe M, Léger T, Desvaux R, Walch L. Discs large 1 (Dlg1) scaffolding protein participates with clathrin and adaptator protein complex 1 (AP-1) in forming Weibel-Palade bodies of endothelial cells. J Biol Chem. 2013;288:13046-56 pubmed 出版商

Pandey M, Baggenstoss B, Washburn J, Harris E, Weigel P. The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans. J Biol Chem. 2013;288:14068-79 pubmed 出版商

Schröder H, Hoffmann S, Hecker M, Korff T, Ludwig T. The tetraspanin network modulates MT1-MMP cell surface trafficking. Int J Biochem Cell Biol. 2013;45:1133-44 pubmed 出版商

Ling L, Voskas D, Woodgett J. Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner. Oncogene. 2013;32:5397-408 pubmed 出版商

Werwein E, Dzuganova M, Usadel C, Klempnauer K. B-Myb switches from Cyclin/Cdk-dependent to Jnk- and p38 kinase-dependent phosphorylation and associates with SC35 bodies after UV stress. Cell Death Dis. 2013;4:e511 pubmed 出版商

Moestue S, Dam C, Gorad S, Kristian A, Bofin A, Mælandsmo G, et al. Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Res. 2013;15:R16 pubmed 出版商

Li Y, Wong K, Walsh K, Gao B, Zang M. Retinoic acid receptor ? stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice. J Biol Chem. 2013;288:10490-504 pubmed 出版商

Pan C, Tsai C, Liu F, Fan M, Sheu M, Hsieh W, et al. Influence of different particle processing on hypocholesterolemic and antiatherogenic activities of yam (Dioscorea pseudojaponica) in cholesterol-fed rabbit model. J Sci Food Agric. 2013;93:1278-83 pubmed 出版商

Wang Y, Wang H, Hegde V, Dubuisson O, Gao Z, Dhurandhar N, et al. Interplay of pro- and anti-inflammatory cytokines to determine lipid accretion in adipocytes. Int J Obes (Lond). 2013;37:1490-8 pubmed 出版商

Edwards T, Helmus M, Koeller K, Bashkin J, Fisher C. Human papillomavirus episome stability is reduced by aphidicolin and controlled by DNA damage response pathways. J Virol. 2013;87:3979-89 pubmed 出版商

Anwar S, Albat C, Krech T, Hasemeier B, Schipper E, Schweitzer N, et al. Concordant hypermethylation of intergenic microRNA genes in human hepatocellular carcinoma as new diagnostic and prognostic marker. Int J Cancer. 2013;133:660-70 pubmed 出版商

Sanders D, Ross Innes C, Beraldi D, Carroll J, Balasubramanian S. Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biol. 2013;14:R6 pubmed 出版商

Ungvari Z, Tucsek Z, Sosnowska D, Toth P, Gautam T, Podlutsky A, et al. Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2013;68:877-91 pubmed 出版商

Brody M, Hacker T, Patel J, Feng L, Sadoshima J, Tevosian S, et al. Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS ONE. 2012;7:e51621 pubmed 出版商

Wydeven N, Young D, Mirkovic K, Wickman K. Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity. Proc Natl Acad Sci U S A. 2012;109:21492-7 pubmed 出版商

Lopez M, Tollervey J, Krastins B, Garces A, Sarracino D, Prakash A, et al. Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells. Aging (Albany NY). 2012;4:823-42 pubmed

Lee J, Hynds R. Divergent cellular pathways of hippocampal memory consolidation and reconsolidation. Hippocampus. 2013;23:233-44 pubmed 出版商

Hirata H, Yimin -, Segawa S, Ozaki M, Kobayashi N, Shigyo T, et al. Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice. PLoS ONE. 2012;7:e49415 pubmed 出版商

Banerjee J, Al Wadei H, Schuller H. Chronic nicotine inhibits the therapeutic effects of gemcitabine on pancreatic cancer in vitro and in mouse xenografts. Eur J Cancer. 2013;49:1152-8 pubmed 出版商

Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. Loss of imprinting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma. PLoS ONE. 2012;7:e49462 pubmed 出版商

Liu H, Gao Z, Cui S, Wang Y, Li B, Lou H, et al. Chemoprevention of intestinal adenomatous polyposis by acetyl-11-keto-beta-boswellic acid in APC(Min/+) mice. Int J Cancer. 2013;132:2667-81 pubmed 出版商

Kalinowski F, Giles K, Candy P, Ali A, Ganda C, Epis M, et al. Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7. PLoS ONE. 2012;7:e47067 pubmed 出版商

Patil S, Gentschev I, Adelfinger M, Donat U, Hess M, Weibel S, et al. Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody. PLoS ONE. 2012;7:e47472 pubmed 出版商

Lin J, Martagón A, Hsueh W, Baxter J, Gustafsson J, Webb P, et al. Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor. Endocrinology. 2012;153:6136-44 pubmed 出版商

Tachibana H, Ogawa D, Matsushita Y, Bruemmer D, Wada J, Teshigawara S, et al. Activation of liver X receptor inhibits osteopontin and ameliorates diabetic nephropathy. J Am Soc Nephrol. 2012;23:1835-46 pubmed 出版商

Wang X, Wang Z, Wu Y, Tang H, Tan L, Wang X, et al. Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway. Mol Neurobiol. 2013;47:373-81 pubmed 出版商

Lin Y, Richards F, Krippendorff B, Bramhall J, Harrington J, Bapiro T, et al. Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells. Br J Cancer. 2012;107:1692-701 pubmed 出版商

Gjerstorff M, Rösner H, Pedersen C, Greve K, Schmidt S, Wilson K, et al. GAGE cancer-germline antigens are recruited to the nuclear envelope by germ cell-less (GCL). PLoS ONE. 2012;7:e45819 pubmed 出版商

Broderick S, Wang X, Simms N, Page McCaw A. Drosophila Ninjurin A induces nonapoptotic cell death. PLoS ONE. 2012;7:e44567 pubmed 出版商

Coenen E, Driessen E, Zwaan C, Stary J, Baruchel A, de Haas V, et al. CBL mutations do not frequently occur in paediatric acute myeloid leukaemia. Br J Haematol. 2012;159:577-84 pubmed 出版商

Radhika M, Ghoshal N, Chatterjee A. Comparison of effectiveness in antitumor activity between flavonoids and polyphenols of the methanolic extract of roots of Potentilla fulgens in breast cancer cells. J Complement Integr Med. 2012;9:Article 24 pubmed 出版商

Mochida G, Ganesh V, de Michelena M, Dias H, Atabay K, Kathrein K, et al. CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nat Genet. 2012;44:1260-4 pubmed 出版商

Jowett J, Okada Y, Leedman P, Curran J, Johnson M, Moses E, et al. ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-?. Immunol Cell Biol. 2012;90:966-73 pubmed 出版商

Zerin T, Kim Y, Hong S, Song H. Quercetin reduces oxidative damage induced by paraquat via modulating expression of antioxidant genes in A549 cells. J Appl Toxicol. 2013;33:1460-7 pubmed 出版商

Rizvi H, Paterson J, Tedoldi S, Ramsay A, Calaminici M, Natkunam Y, et al. Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue. Pathologica. 2012;104:56-64 pubmed

Lake M, Nguyen Q, Ali S, Aboagye E. Development of a novel molecular sensor for imaging estrogen receptor-coactivator protein-protein interactions. PLoS ONE. 2012;7:e44160 pubmed 出版商

Dulin J, Moore M, Grill R. The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord. J Neurotrauma. 2013;30:211-26 pubmed 出版商

Létourneau I, Quinn M, Wang L, Portelance L, Caceres K, Cyr L, et al. Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer. BMC Cancer. 2012;12:379 pubmed 出版商

Schäfer S, Weibel S, Donat U, Zhang Q, Aguilar R, Chen N, et al. Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors. BMC Cancer. 2012;12:366 pubmed 出版商

Lichtenfels R, Mougiakakos D, Johansson C, Dressler S, Recktenwald C, Kiessling R, et al. Comparative expression profiling of distinct T cell subsets undergoing oxidative stress. PLoS ONE. 2012;7:e41345 pubmed 出版商

Sanchez A, Tripathy D, Yin X, Desobry K, Martinez J, Riley J, et al. p38 MAPK: a mediator of hypoxia-induced cerebrovascular inflammation. J Alzheimers Dis. 2012;32:587-97 pubmed 出版商

Muylaert I, Zhao Z, Andersson T, Elias P. Identification of conserved amino acids in the herpes simplex virus type 1 UL8 protein required for DNA synthesis and UL52 primase interaction in the virus replisome. J Biol Chem. 2012;287:33142-52 pubmed

Mihaylova S, Killian A, Mayer K, Pullamsetti S, Schermuly R, Rosengarten B. Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats. J Neuroinflammation. 2012;9:183 pubmed 出版商

Jin Y, Li Z, Hong Z, Xu C, Han J, Choi S, et al. Conjugated linoleic acid synthesis-related protein proteasome subunit ? 5 (PSMA5) is increased by vaccenic acid treatment in goat mammary tissue. J Dairy Sci. 2012;95:4286-97 pubmed 出版商

Gandal M, Sisti J, Klook K, Ortinski P, Leitman V, Liang Y, et al. GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction. Transl Psychiatry. 2012;2:e142 pubmed 出版商

Fehr A, Gualberto N, Savaryn J, Terhune S, Yu D. Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a. PLoS Pathog. 2012;8:e1002789 pubmed 出版商

Lamers F, Schild L, Koster J, Speleman F, Øra I, Westerhout E, et al. Identification of BIRC6 as a novel intervention target for neuroblastoma therapy. BMC Cancer. 2012;12:285 pubmed 出版商

Weigand S, Herting F, Maisel D, Nopora A, Voss E, Schaab C, et al. Global quantitative phosphoproteome analysis of human tumor xenografts treated with a CD44 antagonist. Cancer Res. 2012;72:4329-39 pubmed 出版商

Park Y, Zhao X, Norton M, Taylor J, Eisenberg E, Greene L. Huntingtin fragments and SOD1 mutants form soluble oligomers in the cell. PLoS ONE. 2012;7:e40329 pubmed 出版商

Mizuno A, Yasumuro H, Yoshikawa T, Inami W, Chiba C. MEK-ERK signaling in adult newt retinal pigment epithelium cells is strengthened immediately after surgical induction of retinal regeneration. Neurosci Lett. 2012;523:39-44 pubmed 出版商

Burger van Paassen N, Loonen L, Witte Bouma J, Korteland Van Male A, De Bruijn A, Van Der Sluis M, et al. Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3?, Reg3? and angiogenin-4. PLoS ONE. 2012;7:e38798 pubmed 出版商

Velten M, Britt R, Heyob K, Welty S, Eiberger B, Tipple T, et al. Prenatal inflammation exacerbates hyperoxia-induced functional and structural changes in adult mice. Am J Physiol Regul Integr Comp Physiol. 2012;303:R279-90 pubmed 出版商

Liu Z, Li Y, Tan Y, Xiao M, Zhang J, Radtke F, et al. Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1. PLoS ONE. 2012;7:e38811 pubmed 出版商

Zheng X, Wang X, Ma Z, Gupta Sunkari V, Botusan I, Takeda T, et al. Acute hypoxia induces apoptosis of pancreatic ?-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death Dis. 2012;3:e322 pubmed 出版商

Winter S, Lukes L, Walker R, Welch D, Hunter K. Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis. PLoS Genet. 2012;8:e1002735 pubmed 出版商

Lafontaine J, Tchakarska G, Rodier F, Mes Masson A. Necdin modulates proliferative cell survival of human cells in response to radiation-induced genotoxic stress. BMC Cancer. 2012;12:234 pubmed 出版商

Le Page C, Marineau A, Bonza P, Rahimi K, Cyr L, Labouba I, et al. BTN3A2 expression in epithelial ovarian cancer is associated with higher tumor infiltrating T cells and a better prognosis. PLoS ONE. 2012;7:e38541 pubmed 出版商

Khanjani S, Terzidou V, Johnson M, Bennett P. NF?B and AP-1 drive human myometrial IL8 expression. Mediators Inflamm. 2012;2012:504952 pubmed 出版商

Meng Z, Wang X, Yang Z, Xiang F. Expression of transient receptor potential melastatin 7 up-regulated in the early stage of renal ischemia-reperfusion. Transplant Proc. 2012;44:1206-10 pubmed 出版商

Wold L, Ying Z, Hutchinson K, Velten M, Gorr M, Velten C, et al. Cardiovascular remodeling in response to long-term exposure to fine particulate matter air pollution. Circ Heart Fail. 2012;5:452-61 pubmed 出版商

Chucair Elliott A, Elliott M, Wang J, Moiseyev G, Ma J, Politi L, et al. Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium. J Biol Chem. 2012;287:24092-102 pubmed 出版商

Druz A, Betenbaugh M, Shiloach J. Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation. Nucleic Acids Res. 2012;40:7291-302 pubmed 出版商

Wali J, de Boo H, Derraik J, Phua H, Oliver M, Bloomfield F, et al. Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters. PLoS ONE. 2012;7:e37899 pubmed 出版商

Weischenfeldt J, Waage J, Tian G, Zhao J, Damgaard I, Jakobsen J, et al. Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns. Genome Biol. 2012;13:R35 pubmed 出版商

Herskowitz J, Offe K, Deshpande A, Kahn R, Levey A, Lah J. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-? production. Mol Biol Cell. 2012;23:2645-57 pubmed 出版商

van der Velden Y, Wang L, Van Lohuizen M, Haramis A. The Polycomb group protein Ring1b is essential for pectoral fin development. Development. 2012;139:2210-20 pubmed 出版商

Zhao C, Yue B, Liu H, Sun C, Li W, Qu X. SL-01, an oral gemcitabine derivative, inhibited human cancer growth more potently than gemcitabine. Toxicol Appl Pharmacol. 2012;262:293-300 pubmed 出版商

Dedonder S, Cheng C, Willard L, Boyle D, Ganta R. Transmission electron microscopy reveals distinct macrophage- and tick cell-specific morphological stages of Ehrlichia chaffeensis. PLoS ONE. 2012;7:e36749 pubmed 出版商

Com E, Clavreul A, Lagarrigue M, Michalak S, Menei P, Pineau C. Quantitative proteomic Isotope-Coded Protein Label (ICPL) analysis reveals alteration of several functional processes in the glioblastoma. J Proteomics. 2012;75:3898-913 pubmed 出版商

Wi H, Na E, Yun S, Lee J. The antifungal effect of light emitting diode on Malassezia yeasts. J Dermatol Sci. 2012;67:3-8 pubmed 出版商

Popugaeva E, Witkowski P, Schlegel M, Ulrich R, Auste B, Rang A, et al. Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans. PLoS ONE. 2012;7:e35587 pubmed 出版商

Pan C, Tsai C, Lin W, Chen G, Wu C. Ethanolic Extract of Vitis thunbergii Exhibits Lipid Lowering Properties via Modulation of the AMPK-ACC Pathway in Hypercholesterolemic Rabbits. Evid Based Complement Alternat Med. 2012;2012:436786 pubmed 出版商

Chou M, Chuang J, Eng H, Tsai P, Hsieh C, Liu H, et al. Effects of hepatocyte CD14 upregulation during cholestasis on endotoxin sensitivity. PLoS ONE. 2012;7:e34903 pubmed 出版商

Pranski E, Dalal N, Herskowitz J, Orr A, Roesch L, Fritz J, et al. Neuronal RING finger protein 11 (RNF11) regulates canonical NF-?B signaling. J Neuroinflammation. 2012;9:67 pubmed 出版商

Thapa A, Morris L, Xu J, Ma H, Michalakis S, Biel M, et al. Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency. J Biol Chem. 2012;287:18018-29 pubmed 出版商

Sharma A, Yilmaz A, Marsh K, Cochrane A, Boris Lawrie K. Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity. PLoS Pathog. 2012;8:e1002612 pubmed 出版商

Liu H, Gao Z, Cui S, Sun D, Wang Y, Zhao C, et al. Inhibition of intestinal adenoma formation in APC(Min/+) mice by Riccardin D, a natural product derived from liverwort plant Dumortiera hirsuta. PLoS ONE. 2012;7:e33243 pubmed 出版商

Zhou C, Wong O, Masters J, Williamson M. Effect of cancer-associated mutations in the PlexinB1 gene. Mol Cancer. 2012;11:11 pubmed 出版商

Laberge R, Zhou L, Sarantos M, Rodier F, Freund A, de Keizer P, et al. Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell. 2012;11:569-78 pubmed 出版商

Cheever T, Li B, Ervasti J. Restricted morphological and behavioral abnormalities following ablation of ?-actin in the brain. PLoS ONE. 2012;7:e32970 pubmed 出版商

Kucab J, Phillips D, Arlt V. Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts. Environ Mol Mutagen. 2012;53:207-17 pubmed 出版商

Frolov I, Akhrymuk M, Akhrymuk I, Atasheva S, Frolova E. Early events in alphavirus replication determine the outcome of infection. J Virol. 2012;86:5055-66 pubmed 出版商

Xu F, Burk D, Gao Z, Yin J, Zhang X, Weng J, et al. Angiogenic deficiency and adipose tissue dysfunction are associated with macrophage malfunction in SIRT1-/- mice. Endocrinology. 2012;153:1706-16 pubmed 出版商

Polettini J, Vieira E, Santos M, Peraçoli J, Witkin S, da Silva M. Interleukin 18 messenger RNA and proIL-18 protein expression in chorioamniotic membranes from pregnant women with preterm prelabor rupture of membranes. Eur J Obstet Gynecol Reprod Biol. 2012;161:134-9 pubmed 出版商

Nicolas C, Peineau S, Amici M, Csaba Z, Fafouri A, Javalet C, et al. The Jak/STAT pathway is involved in synaptic plasticity. Neuron. 2012;73:374-90 pubmed 出版商

Cintra D, Ropelle E, Moraes J, Pauli J, Morari J, Souza C, et al. Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity. PLoS ONE. 2012;7:e30571 pubmed 出版商

Collett G, Goh X, Linton E, Redman C, Sargent I. RhoE is regulated by cyclic AMP and promotes fusion of human BeWo choriocarcinoma cells. PLoS ONE. 2012;7:e30453 pubmed 出版商

Titus M, Zeithaml B, Kantor B, Li X, Haack K, Moore D, et al. Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer. PLoS ONE. 2012;7:e30192 pubmed 出版商

Xue X, Sun D, Sun C, Liu H, Yue B, Zhao C, et al. Inhibitory effect of riccardin D on growth of human non-small cell lung cancer: in vitro and in vivo studies. Lung Cancer. 2012;76:300-8 pubmed 出版商

Zhou B, Liu Y, Kahn M, Ann D, Han A, Wang H, et al. Interactions between ?-catenin and transforming growth factor-? signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP). J Biol Chem. 2012;287:7026-38 pubmed 出版商

van Steensel L, Paridaens D, Van Meurs M, van Hagen P, van den Bosch W, Kuijpers R, et al. Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathy. J Clin Endocrinol Metab. 2012;97:E400-8 pubmed 出版商

Bai X, Wu X, Wang X, Liu X, Song Y, Gao F, et al. Inhibition of mammalian muscle differentiation by excretory secretory products of muscle larvae of Trichinella spiralis in vitro. Parasitol Res. 2012;110:2481-90 pubmed 出版商

Schaller T, Ocwieja K, Rasaiyaah J, Price A, Brady T, Roth S, et al. HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency. PLoS Pathog. 2011;7:e1002439 pubmed 出版商

Huseby S, Gausdal G, Keen T, Kjærland E, Krakstad C, Myhren L, et al. Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription. Cell Death Dis. 2011;2:e237 pubmed 出版商

Bubolz A, Mendoza S, Zheng X, Zinkevich N, Li R, Gutterman D, et al. Activation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling. Am J Physiol Heart Circ Physiol. 2012;302:H634-42 pubmed 出版商

Jardon M, Sattha B, Braasch K, Leung A, Cote H, Butler M, et al. Inhibition of glutamine-dependent autophagy increases t-PA production in CHO cell fed-batch processes. Biotechnol Bioeng. 2012;109:1228-38 pubmed 出版商

Carthy J, Luo Z, McManus B. WNT3A induces a contractile and secretory phenotype in cultured vascular smooth muscle cells that is associated with increased gap junction communication. Lab Invest. 2012;92:246-55 pubmed 出版商

Magalhaes M, Larson D, Mader C, Bravo Cordero J, Gil Henn H, Oser M, et al. Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol. 2011;195:903-20 pubmed 出版商

Seitz V, Butzhammer P, Hirsch B, Hecht J, Gütgemann I, Ehlers A, et al. Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma. PLoS ONE. 2011;6:e26837 pubmed 出版商

Zerin T, Kim Y, Hong S, Song H. Protective effect of methylprednisolone on paraquat-induced A549 cell cytotoxicity via induction of efflux transporter, P-glycoprotein expression. Toxicol Lett. 2012;208:101-7 pubmed 出版商

Gumy Pause F, Pardo B, Khoshbeen Boudal M, Ansari M, Gayet Ageron A, Sappino A, et al. GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma. Genes Chromosomes Cancer. 2012;51:174-85 pubmed 出版商

Fellerhoff B, Gu S, Laumbacher B, Nerlich A, Weiss E, Glas J, et al. The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. Cancer Res. 2011;71:7145-54 pubmed 出版商

Wan M, Easton R, Gleason C, Monks B, Ueki K, Kahn C, et al. Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity. Mol Cell Biol. 2012;32:96-106 pubmed 出版商

Singh N, Paul R, Sichler M, Moaddel R, Bernier M, Wainer I. Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity. Anal Biochem. 2012;421:460-6 pubmed 出版商

Bailey Downs L, Mitschelen M, Sosnowska D, Toth P, Pinto J, Ballabh P, et al. Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging. J Gerontol A Biol Sci Med Sci. 2012;67:313-29 pubmed 出版商

Kurokawa Y, Sekiguchi F, Kubo S, Yamasaki Y, Matsuda S, Okamoto Y, et al. Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide. Biochem Biophys Res Commun. 2011;414:727-32 pubmed 出版商

Hess M, Stritzker J, Härtl B, Sturm J, Gentschev I, Szalay A. Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies. J Transl Med. 2011;9:172 pubmed 出版商

van Dijk K, Berendse H, Drukarch B, Fratantoni S, Pham T, Piersma S, et al. The proteome of the locus ceruleus in Parkinson's disease: relevance to pathogenesis. Brain Pathol. 2012;22:485-98 pubmed 出版商

Velten M, Hutchinson K, Gorr M, Wold L, Lucchesi P, Rogers L. Systemic maternal inflammation and neonatal hyperoxia induces remodeling and left ventricular dysfunction in mice. PLoS ONE. 2011;6:e24544 pubmed 出版商

Le Page C, Koumakpayi I, Péant B, Delvoye N, Saad F, Mes Masson A. ErbB2/Her-2 regulates the expression of Akt2 in prostate cancer cells. Prostate. 2012;72:777-88 pubmed 出版商

Grammas P, Tripathy D, Sanchez A, Yin X, Luo J. Brain microvasculature and hypoxia-related proteins in Alzheimer's disease. Int J Clin Exp Pathol. 2011;4:616-27 pubmed

Lemieux M, Cheng Z, Zhou Q, White R, Cornell J, Kung A, et al. Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells. PLoS ONE. 2011;6:e24153 pubmed 出版商

Lamers F, van der Ploeg I, Schild L, Ebus M, Koster J, Hansen B, et al. Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe. Endocr Relat Cancer. 2011;18:657-68 pubmed 出版商

Huang R, Cheung N, Vider J, Cheung I, Gerald W, Tickoo S, et al. MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas. FASEB J. 2011;25:4138-49 pubmed 出版商

Yuan C, Zhang Y, Cheng Y, Xue X, Xu W, Qu X. A112, a tamibarotene dimethylaminoethyl ester, may inhibit human leukemia cell growth more potently than tamibarotene. Leuk Lymphoma. 2012;53:295-304 pubmed 出版商

Li Y, Yu Y, Zhang Y, Zhou Y, Li C, Zhu J, et al. MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway. Cancer Sci. 2011;102:2043-50 pubmed 出版商

Solon C, Franci D, Ignacio Souza L, Romanatto T, Roman E, Arruda A, et al. Taurine enhances the anorexigenic effects of insulin in the hypothalamus of rats. Amino Acids. 2012;42:2403-10 pubmed 出版商

Lund I, Nielsen B, Almholt K, Rønø B, Hald A, Illemann M, et al. Concomitant lack of MMP9 and uPA disturbs physiological tissue remodeling. Dev Biol. 2011;358:56-67 pubmed 出版商

Leucker T, Bienengraeber M, Muravyeva M, Baotic I, Weihrauch D, Brzezinska A, et al. Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. J Mol Cell Cardiol. 2011;51:803-11 pubmed 出版商

Ruthala K, Gadi J, Lee J, Yoon H, Chung H, Kim M. Hoxc8 downregulates Mgl1 tumor suppressor gene expression and reduces its concomitant function on cell adhesion. Mol Cells. 2011;32:273-9 pubmed 出版商

Tikhmyanova N, Golemis E. NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation. PLoS ONE. 2011;6:e22102 pubmed 出版商

Hamouchene H, Arlt V, Giddings I, Phillips D. Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene. BMC Genomics. 2011;12:333 pubmed 出版商

Merlini M, Meyer E, Ulmann Schuler A, Nitsch R. Vascular ?-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcA? mice. Acta Neuropathol. 2011;122:293-311 pubmed 出版商

Zhang H, Lu W, Zhao Y, Rong P, Cao R, Gu W, et al. Adipocytes derived from human bone marrow mesenchymal stem cells exert inhibitory effects on osteoblastogenesis. Curr Mol Med. 2011;11:489-502 pubmed

Soontornniyomkij B, Everall I, Chana G, Tsuang M, Achim C, Soontornniyomkij V. Tyrosine kinase B protein expression is reduced in the cerebellum of patients with bipolar disorder. J Affect Disord. 2011;133:646-54 pubmed 出版商

Li C, Nyman J, Braithwaite A, Eccles M. PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein. Oncogene. 2011;30:4824-34 pubmed 出版商

Barkefors I, Fuchs P, Heldin J, Bergström T, Forsberg Nilsson K, Kreuger J. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells. J Biol Chem. 2011;286:24189-99 pubmed 出版商

Hvid H, Fels J, Kirk R, Thorup I, Jensen H, Hansen B, et al. In situ phosphorylation of Akt and ERK1/2 in rat mammary gland, colon, and liver following treatment with human insulin and IGF-1. Toxicol Pathol. 2011;39:623-40 pubmed 出版商

Gao Z, Zhang J, Kheterpal I, Kennedy N, Davis R, Ye J. Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity. J Biol Chem. 2011;286:22227-34 pubmed 出版商

Holmes K, Hurtado A, Brown G, Launchbury R, Ross Innes C, Hadfield J, et al. Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells. Proc Natl Acad Sci U S A. 2012;109:2748-53 pubmed 出版商

Chen M, Atkins C, Bruce S, Khan A, Liu Y, Alcorn J. Infant formula alters surfactant protein A (SP-A) and SP-B expression in pulmonary epithelial cells. Pediatr Pulmonol. 2011;46:903-12 pubmed 出版商

Koumakpayi I, Le Page C, Delvoye N, Saad F, Mes Masson A. Macropinocytosis inhibitors and Arf6 regulate ErbB3 nuclear localization in prostate cancer cells. Mol Carcinog. 2011;50:901-12 pubmed 出版商

Csak T, Dolganiuc A, Kodys K, Nath B, Petrasek J, Bala S, et al. Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. Hepatology. 2011;53:1917-31 pubmed 出版商

Goyeneche A, Seidel E, Telleria C. Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2. Invest New Drugs. 2012;30:967-80 pubmed 出版商

Zhang J, Henagan T, Gao Z, Ye J. Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation. Endocrinology. 2011;152:1829-38 pubmed 出版商

Mysliwiec M, Bresnick E, Lee Y. Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression. J Biol Chem. 2011;286:17193-204 pubmed 出版商

Seo J, Lee K, Kim T, Baek I, Im J, Han P. Behavioral stress causes mitochondrial dysfunction via ABAD up-regulation and aggravates plaque pathology in the brain of a mouse model of Alzheimer disease. Free Radic Biol Med. 2011;50:1526-35 pubmed 出版商

FRIEDMAN N, Barzily Rokni M, Isaac S, Eden A. The histone H2A variant macroH2A1 does not localize to the centrosome. PLoS ONE. 2011;6:e17262 pubmed 出版商

Wang X, Gao Z, Xue X, Cheng Y, Yue P, Fang X, et al. N1-acetyl substituted pyrrolidine derivative CIP-A5: a novel compound that could ameliorate liver cirrhosis through modulation of hepatic stellate cell activity. Toxicol In Vitro. 2011;25:897-904 pubmed 出版商

Bang Berthelsen C, Pedersen L, Fløyel T, Hagedorn P, Gylvin T, Pociot F. Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes. BMC Genomics. 2011;12:97 pubmed 出版商

Vares G, Wang B, Tanaka K, Shang Y, Taki K, Nakajima T, et al. Gene silencing of Tead3 abrogates radiation-induced adaptive response in cultured mouse limb bud cells. J Radiat Res. 2011;52:39-46 pubmed

Nejatollahi F, Asgharpour M, Jaberipour M. Down-regulation of vascular endothelial growth factor expression by anti-Her2/neu single chain antibodies. Med Oncol. 2012;29:378-83 pubmed 出版商

Mengatto C, Mussano F, Honda Y, Colwell C, Nishimura I. Circadian rhythm and cartilage extracellular matrix genes in osseointegration: a genome-wide screening of implant failure by vitamin D deficiency. PLoS ONE. 2011;6:e15848 pubmed 出版商

Hofmann E, Grummt F, Szalay A. Vaccinia virus GLV-1h237 carrying a Walker A motif mutation of mouse Cdc6 protein enhances human breast tumor therapy in mouse xenografts. Int J Oncol. 2011;38:871-8 pubmed 出版商

Ferraz de Souza B, Hudson Davies R, Lin L, Parnaik R, Hubank M, Dattani M, et al. Sterol O-acyltransferase 1 (SOAT1, ACAT) is a novel target of steroidogenic factor-1 (SF-1, NR5A1, Ad4BP) in the human adrenal. J Clin Endocrinol Metab. 2011;96:E663-8 pubmed 出版商

Mittal S, Aslam A, Doidge R, Medica R, Winkler G. The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence. Mol Biol Cell. 2011;22:748-58 pubmed 出版商

Ungvari Z, Bailey Downs L, Gautam T, Jimenez R, Losonczy G, Zhang C, et al. Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol. 2011;300:H1133-40 pubmed 出版商

Dunston C, Griffiths H, Lambert P, Staddon S, Vernallis A. Proteomic analysis of the anti-inflammatory action of minocycline. Proteomics. 2011;11:42-51 pubmed 出版商

Wilson J, Zhang C, Huys A, Richardson C. Human Ago2 is required for efficient microRNA 122 regulation of hepatitis C virus RNA accumulation and translation. J Virol. 2011;85:2342-50 pubmed 出版商

Jazdzewski K, Boguslawska J, Jendrzejewski J, Liyanarachchi S, Pachucki J, Wardyn K, et al. Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC). J Clin Endocrinol Metab. 2011;96:E546-53 pubmed 出版商

Hurtado A, Holmes K, Ross Innes C, Schmidt D, Carroll J. FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat Genet. 2011;43:27-33 pubmed 出版商

Yeh F, Dong M, Yao J, Tepp W, Lin G, Johnson E, et al. SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathog. 2010;6:e1001207 pubmed 出版商

Deng X, Li X, Shen Y, Qiu Y, Shi Z, Shao D, et al. The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities. Virol J. 2010;7:348 pubmed 出版商

Piekielko Witkowska A, Wiszomirska H, Wojcicka A, Poplawski P, Boguslawska J, Tanski Z, et al. Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors. PLoS ONE. 2010;5:e13690 pubmed 出版商

Smolen G, Zhang J, Zubrowski M, Edelman E, Luo B, Yu M, et al. A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration. Genes Dev. 2010;24:2654-65 pubmed 出版商

Haebig K, Gloeckner C, Miralles M, Gillardon F, Schulte C, Riess O, et al. ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2. PLoS ONE. 2010;5:e13762 pubmed 出版商

Kuipers J, Coenen E, Balgobind B, Stary J, Baruchel A, de Haas V, et al. High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23). Blood. 2011;117:928-35 pubmed 出版商

Barzily Rokni M, FRIEDMAN N, Ron Bigger S, Isaac S, Michlin D, Eden A. Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A). Nucleic Acids Res. 2011;39:1326-35 pubmed 出版商

Sher F, Boddeke E, Copray S. Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells. Cell Reprogram. 2011;13:1-6 pubmed 出版商

Doi T, Maniwa Y, Tanaka Y, Tane S, Hashimoto S, Ohno Y, et al. MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell. Exp Mol Pathol. 2011;90:91-6 pubmed 出版商

Liu J, Jiang Z, Liu L, Zhang Y, Zhang S, Xiao J, et al. Triptolide induces adverse effect on reproductive parameters of female Sprague-Dawley rats. Drug Chem Toxicol. 2011;34:1-7 pubmed 出版商

Leonard S, Ring R. Immunohistochemical localization of the neuropeptide S receptor in the rat central nervous system. Neuroscience. 2011;172:153-63 pubmed 出版商

Shimada M, Haruta M, Niida H, Sawamoto K, Nakanishi M. Protein phosphatase 1? is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage. EMBO Rep. 2010;11:883-9 pubmed 出版商

Barrès V, Ouellet V, Lafontaine J, Tonin P, Provencher D, Mes Masson A. An essential role for Ran GTPase in epithelial ovarian cancer cell survival. Mol Cancer. 2010;9:272 pubmed 出版商

Oleksiewicz M, Bonnesen C, Hegelund A, Lundby A, Holm G, Jensen M, et al. Comparison of intracellular signalling by insulin and the hypermitogenic AspB10 analogue in MCF-7 breast adenocarcinoma cells. J Appl Toxicol. 2011;31:329-41 pubmed 出版商

Giles K, Barker A, Zhang P, Epis M, Leedman P. MicroRNA regulation of growth factor receptor signaling in human cancer cells. Methods Mol Biol. 2011;676:147-63 pubmed 出版商

Xue X, Qu X, Gao Z, Sun C, Liu H, Zhao C, et al. Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II. Invest New Drugs. 2012;30:212-22 pubmed 出版商

Getz J, Lin D, Medeiros D. The cardiac copper chaperone proteins Sco1 and CCS are up-regulated, but Cox 1 and Cox4 are down-regulated, by copper deficiency. Biol Trace Elem Res. 2011;143:368-77 pubmed 出版商

Zhang C, Jia P, Jia Y, Li Y, Webster K, Huang X, et al. Anoxia, acidosis, and intergenic interactions selectively regulate methionine sulfoxide reductase transcriptions in mouse embryonic stem cells. J Cell Biochem. 2011;112:98-106 pubmed 出版商

Pütz S, Vogiatzi F, Stiewe T, Sickmann A. Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE. Mol Cancer. 2010;9:254 pubmed 出版商

Seubert C, Stritzker J, Hess M, Donat U, Sturm J, Chen N, et al. Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a ?-galactosidase-activatable prodrug seco-analog of duocarmycin SA. Cancer Gene Ther. 2011;18:42-52 pubmed 出版商

Rodig S, Kutok J, Paterson J, Nitta H, Zhang W, Chapuy B, et al. The pre-B-cell receptor associated protein VpreB3 is a useful diagnostic marker for identifying c-MYC translocated lymphomas. Haematologica. 2010;95:2056-62 pubmed 出版商

Narayan P, Dragunow M. High content analysis of histone acetylation in human cells and tissues. J Neurosci Methods. 2010;193:54-61 pubmed 出版商

Gibbons H, Smith A, Teoh H, Bergin P, Mee E, Faull R, et al. Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures. Neurobiol Dis. 2011;41:96-103 pubmed 出版商

Zhong L, Zhu J, Lv T, Chen G, Sun H, Yang X, et al. Ethanol and its metabolites induce histone lysine 9 acetylation and an alteration of the expression of heart development-related genes in cardiac progenitor cells. Cardiovasc Toxicol. 2010;10:268-74 pubmed 出版商

Fan J, Li L, Small D, Rassool F. Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy. Blood. 2010;116:5298-305 pubmed 出版商

Poulogiannis G, McIntyre R, Dimitriadi M, Apps J, Wilson C, Ichimura K, et al. PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice. Proc Natl Acad Sci U S A. 2010;107:15145-50 pubmed 出版商

Bateman N, Sun M, Hood B, Flint M, Conrads T. Defining central themes in breast cancer biology by differential proteomics: conserved regulation of cell spreading and focal adhesion kinase. J Proteome Res. 2010;9:5311-24 pubmed 出版商

Na J, Furue M, Andrews P. Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal. Stem Cell Res. 2010;5:157-69 pubmed 出版商

Rossler R, Boddeke E, Copray S. Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons. Neuroscience. 2010;170:417-28 pubmed 出版商

Kim M, Kaduwal S, Yang D, Choi K. Bone morphogenetic protein 4 stimulates attachment of neurospheres and astrogenesis of neural stem cells in neurospheres via phosphatidylinositol 3 kinase-mediated upregulation of N-cadherin. Neuroscience. 2010;170:8-15 pubmed 出版商

Gentschev I, Ehrig K, Donat U, Hess M, Rudolph S, Chen N, et al. Significant Growth Inhibition of Canine Mammary Carcinoma Xenografts following Treatment with Oncolytic Vaccinia Virus GLV-1h68. J Oncol. 2010;2010:736907 pubmed 出版商

Ash E, Alavijeh M, Palmer A, Mitchelmore C, Howlett D, Francis P, et al. Neurochemical changes in a double transgenic mouse model of Alzheimer's disease fed a pro-oxidant diet. Neurochem Int. 2010;57:504-11 pubmed 出版商

Kennedy A, McBryan T, Enders G, Johnson F, Zhang R, Adams P. Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci. Cell Div. 2010;5:16 pubmed 出版商

Weiss E, Ramljak S, Asif A, Ciesielczyk B, Schmitz M, Gawinecka J, et al. Cellular prion protein overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: a proteomic study. Neuroscience. 2010;169:1640-50 pubmed 出版商

Fuchs F, Pau G, Kranz D, Sklyar O, Budjan C, Steinbrink S, et al. Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol. 2010;6:370 pubmed 出版商

Pan C, Hsieh I, Liu F, Hsieh W, Sheu M, Koizumi A, et al. Effects of a Chinese herbal health formula, "Gan-Lu-Yin", on angiogenesis. J Agric Food Chem. 2010;58:7685-92 pubmed 出版商

Jun J, Lau L. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol. 2010;12:676-85 pubmed 出版商

Naito Y, Tsujino T, Akahori H, Ohyanagi M, Mitsuno M, Miyamoto Y, et al. Augmented cannabinoid receptors expression in human aortic valve stenosis. Int J Cardiol. 2010;145:535-7 pubmed 出版商

Collett G, Linton E, Redman C, Sargent I. Downregulation of caveolin-1 enhances fusion of human BeWo choriocarcinoma cells. PLoS ONE. 2010;5:e10529 pubmed 出版商

Wilson J, Blom E, Cunningham R, Xiao Y, Kupfer G, Jones N. Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutat Res. 2010;689:12-20 pubmed 出版商

Choi J, Park G, Na E, Wi H, Lee S, Lee J. Molecular changes following topical photodynamic therapy using methyl aminolaevulinate in mouse skin. J Dermatol Sci. 2010;58:198-203 pubmed 出版商

Kamphausen E, Kellert C, Abbas T, Akkad N, Tenzer S, Pawelec G, et al. Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma. Cancer Immunol Immunother. 2010;59:1273-84 pubmed 出版商

Damek Poprawa M, Stefanik D, Levin L, Akintoye S. Human bone marrow stromal cells display variable anatomic site-dependent response and recovery from irradiation. Arch Oral Biol. 2010;55:358-64 pubmed 出版商

Parvatiyar K, Barber G, Harhaj E. TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases. J Biol Chem. 2010;285:14999-5009 pubmed 出版商

Avery S, Zafarana G, Gokhale P, Andrews P. The role of SMAD4 in human embryonic stem cell self-renewal and stem cell fate. Stem Cells. 2010;28:863-73 pubmed 出版商

Aumo L, Rusten M, Mellgren G, Bakke M, Lewis A. Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. Endocrinology. 2010;151:2151-61 pubmed 出版商

Paiva M, Goncalves L, Providencia L, Davidson S, Yellon D, Mocanu M. Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction. Cardiovasc Drugs Ther. 2010;24:25-32 pubmed 出版商

Schmidt D, Schwalie P, Ross Innes C, Hurtado A, Brown G, Carroll J, et al. A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res. 2010;20:578-88 pubmed 出版商

Muylaert I, Elias P. Contributions of nucleotide excision repair, DNA polymerase eta, and homologous recombination to replication of UV-irradiated herpes simplex virus type 1. J Biol Chem. 2010;285:13761-8 pubmed 出版商

Lu M, Bränström R, Berglund E, Höög A, Björklund P, Westin G, et al. Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid. J Mol Endocrinol. 2010;44:285-94 pubmed 出版商

Sánchez Quiles V, Santamaria E, Segura V, Sesma L, Prieto J, Corrales F. Prohibitin deficiency blocks proliferation and induces apoptosis in human hepatoma cells: molecular mechanisms and functional implications. Proteomics. 2010;10:1609-20 pubmed 出版商

Han Y, Huang C, Sun X, Xiang B, Wang M, Yeh E, et al. SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress. J Biol Chem. 2010;285:12906-15 pubmed 出版商

Mandriota S, Buser R, Lesne L, Stouder C, Favaudon V, Maechler P, et al. Ataxia telangiectasia mutated (ATM) inhibition transforms human mammary gland epithelial cells. J Biol Chem. 2010;285:13092-106 pubmed 出版商

Du R, Long J, Yao J, Dong Y, Yang X, Tang S, et al. Subcellular quantitative proteomics reveals multiple pathway cross-talk that coordinates specific signaling and transcriptional regulation for the early host response to LPS. J Proteome Res. 2010;9:1805-21 pubmed 出版商

Terada N, Shimizu Y, Kamba T, Inoue T, Maeno A, Kobayashi T, et al. Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model. Cancer Res. 2010;70:1606-15 pubmed 出版商

Bilotas M, Meresman G, Buquet R, Sueldo C, Barañao R. Effect of vascular endothelial growth factor and interleukin-1beta on apoptosis in endometrial cell cultures from patients with endometriosis and controls. J Reprod Immunol. 2010;84:193-8 pubmed 出版商

Garrel C, Fowler P, Al Gubory K. Developmental changes in antioxidant enzymatic defences against oxidative stress in sheep placentomes. J Endocrinol. 2010;205:107-16 pubmed 出版商

Yoshikawa T, Hill T, Yoshikawa N, Popov V, Galindo C, Garner H, et al. Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection. PLoS ONE. 2010;5:e8729 pubmed 出版商

Ross Innes C, Stark R, Holmes K, Schmidt D, Spyrou C, Russell R, et al. Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer. Genes Dev. 2010;24:171-82 pubmed 出版商

Tomiyama K, Maeda R, Urakawa I, Yamazaki Y, Tanaka T, Ito S, et al. Relevant use of Klotho in FGF19 subfamily signaling system in vivo. Proc Natl Acad Sci U S A. 2010;107:1666-71 pubmed 出版商

Altonsy M, Andrews S, Tuohy K. Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enteropathogenic bacteria: mediation by the mitochondrial pathway. Int J Food Microbiol. 2010;137:190-203 pubmed 出版商

Sánchez Sánchez A, Camp E, Garcia Espana A, Leal Tassias A, Mullor J. Medaka Oct4 is expressed during early embryo development, and in primordial germ cells and adult gonads. Dev Dyn. 2010;239:672-9 pubmed 出版商

Leitao B, Jones M, Fusi L, Higham J, Lee Y, Takano M, et al. Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals. FASEB J. 2010;24:1541-51 pubmed 出版商

Hu Y, Li W, Lu L, Cai J, Xian X, Zhang M, et al. An anti-nociceptive role for ceftriaxone in chronic neuropathic pain in rats. Pain. 2010;148:284-301 pubmed 出版商

Arruda A, Milanski M, Romanatto T, Solon C, Coope A, Alberici L, et al. Hypothalamic actions of tumor necrosis factor alpha provide the thermogenic core for the wastage syndrome in cachexia. Endocrinology. 2010;151:683-94 pubmed 出版商

Lizé M, Pilarski S, Dobbelstein M. E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis. Cell Death Differ. 2010;17:452-8 pubmed 出版商

Kaczocha M, Glaser S, Chae J, Brown D, Deutsch D. Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. J Biol Chem. 2010;285:2796-806 pubmed 出版商

Bonnesen C, Nelander G, Hansen B, Jensen P, Krabbe J, Jensen M, et al. Synchronization in G0/G1 enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin. Cell Biol Toxicol. 2010;26:293-307 pubmed 出版商

HERRERA J, Haywood Watson R, Grill R. Acute and chronic deficits in the urinary bladder after spinal contusion injury in the adult rat. J Neurotrauma. 2010;27:423-31 pubmed 出版商

Russo L, Peano B, Trivedi S, Cavalcanto T, Olenchock B, Caruso J, et al. Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus. Reprod Biol Endocrinol. 2009;7:124 pubmed 出版商

Wong F, Stanley E. Rab3a interacting molecule (RIM) and the tethering of pre-synaptic transmitter release site-associated CaV2.2 calcium channels. J Neurochem. 2010;112:463-73 pubmed 出版商

Seliger B, Handke D, Schabel E, Bukur J, Lichtenfels R, Dammann R. Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma. J Transl Med. 2009;7:90 pubmed 出版商

Skoblenick K, Argintaru N, Xu Y, Dyck B, Basu D, Tan M, et al. Role of AP-2alpha transcription factor in the regulation of synapsin II gene expression by dopamine D1 and D2 receptors. J Mol Neurosci. 2010;41:267-77 pubmed 出版商

Li Q, Yin W, Cai M, Liu Y, Hou H, Shen Q, et al. NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF1 and CYP7A1. J Endocrinol. 2010;204:47-56 pubmed 出版商

Egerod F, Brunner N, Svendsen J, Oleksiewicz M. PPARalpha and PPARgamma are co-expressed, functional and show positive interactions in the rat urinary bladder urothelium. J Appl Toxicol. 2010;30:151-62 pubmed 出版商

Knudsen K, Nelander Holm G, Krabbe J, Listov Saabye N, Kiehr B, Dufva M, et al. Driving gradual endogenous c-myc overexpression by flow-sorting: intracellular signaling and tumor cell phenotype correlate with oncogene expression. Arch Toxicol. 2009;83:1061-74 pubmed 出版商

Huber M, Guan T, Gerace L. Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation. Mol Cell Biol. 2009;29:5718-28 pubmed 出版商

Brandon E, Gu J, Cantwell L, He Z, Wallace G, Hall J. Obesity promotes melanoma tumor growth: role of leptin. Cancer Biol Ther. 2009;8:1871-9 pubmed

Kozhemyakina E, Cohen T, Yao T, Lassar A. Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway. Mol Cell Biol. 2009;29:5751-62 pubmed 出版商

Berger A, Cortese G, Amodeo K, Weihofen A, Letai A, LaVoie M. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Hum Mol Genet. 2009;18:4317-28 pubmed 出版商

Zhang Z, Sun H, Dai H, Walsh R, Imakura M, Schelter J, et al. MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Cell Cycle. 2009;8:2756-68 pubmed

Tanriover G, Sati L, Tekcan M, Demir N, Gunel M, Celik Ozenci C. Presence of the brain proteins cerebral cavernous malformation-2 and cerebral cavernous malformation-3 in rat testes and their potential role in experimental varicocele. Fertil Steril. 2010;93:2716-22 pubmed 出版商

Tomasini A, Schuler A, Zebala J, Mayer A. PhotoMorphs: a novel light-activated reagent for controlling gene expression in zebrafish. Genesis. 2009;47:736-43 pubmed 出版商

Grabski A, Shimizu T, Deou J, Mahoney W, Reidy M, Daum G. Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. Arterioscler Thromb Vasc Biol. 2009;29:1644-50 pubmed 出版商

Epis M, Giles K, Barker A, Kendrick T, Leedman P. miR-331-3p regulates ERBB-2 expression and androgen receptor signaling in prostate cancer. J Biol Chem. 2009;284:24696-704 pubmed 出版商

Kobayashi T, Nakamura E, Shimizu Y, Terada N, Maeno A, Kobori G, et al. Restoration of cyclin D2 has an inhibitory potential on the proliferation of LNCaP cells. Biochem Biophys Res Commun. 2009;387:196-201 pubmed 出版商

Wang N, Zhang P, Guo X, Xie J, Huo R, Wang F, et al. Comparative proteome profile of immature rat ovary during primordial follicle assembly and development. Proteomics. 2009;9:3425-34 pubmed 出版商

Reiss A, Anwar K, Merrill J, Chan E, Awadallah N, Cronstein B, et al. Plasma from systemic lupus patients compromises cholesterol homeostasis: a potential mechanism linking autoimmunity to atherosclerotic cardiovascular disease. Rheumatol Int. 2010;30:591-8 pubmed 出版商

Sher F, van Dam G, Boddeke E, Copray S. Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model. Stem Cells. 2009;27:1582-91 pubmed 出版商

Bruce S, Atkins C, Colasurdo G, Alcorn J. Respiratory syncytial virus infection alters surfactant protein A expression in human pulmonary epithelial cells by reducing translation efficiency. Am J Physiol Lung Cell Mol Physiol. 2009;297:L559-67 pubmed 出版商

Liu J, Jiang Z, Xiao J, Zhang Y, Lin S, Duan W, et al. Effects of triptolide from Tripterygium wilfordii on ERalpha and p53 expression in two human breast cancer cell lines. Phytomedicine. 2009;16:1006-13 pubmed 出版商

Hoefer M, Illges H. Ectodomain shedding and generation of two carboxy-terminal fragments of human complement receptor 2/CD21. Mol Immunol. 2009;46:2630-9 pubmed 出版商

Maekawa T, Maniwa Y, Doi T, Nishio W, Yoshimura M, Ohbayashi C, et al. Expression and localization of FOXO1 in non-small cell lung cancer. Oncol Rep. 2009;22:57-64 pubmed

Haslinger A, Schwarz T, Covic M, Lie D. Expression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesis. Eur J Neurosci. 2009;29:2103-14 pubmed 出版商

Foltz G, Yoon J, Lee H, Ryken T, Sibenaller Z, Ehrich M, et al. DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis. Oncogene. 2009;28:2667-77 pubmed 出版商

Akbari M, Pena Diaz J, Andersen S, Liabakk N, Otterlei M, Krokan H. Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity. DNA Repair (Amst). 2009;8:834-43 pubmed 出版商

Chen X, Choi I, Chang T, Noh Y, Shin C, Wu C, et al. Pretreatment with interferon-gamma protects microglia from oxidative stress via up-regulation of Mn-SOD. Free Radic Biol Med. 2009;46:1204-10 pubmed 出版商

Gao Z, Yin J, Zhang J, He Q, McGuinness O, Ye J. Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K. J Biol Chem. 2009;284:18368-76 pubmed 出版商

Rogers S, Said A, Corcuera D, McLaughlin D, Kell P, Doctor A. Hypoxia limits antioxidant capacity in red blood cells by altering glycolytic pathway dominance. FASEB J. 2009;23:3159-70 pubmed 出版商

Seo J, Kim T, Leem Y, Lee K, Park S, Baek I, et al. SK-PC-B70M confers anti-oxidant activity and reduces Abeta levels in the brain of Tg2576 mice. Brain Res. 2009;1261:100-8 pubmed 出版商

Yin J, Zuberi A, Gao Z, Liu D, Liu Z, Ye J. Shilianhua extract inhibits GSK-3beta and promotes glucose metabolism. Am J Physiol Endocrinol Metab. 2009;296:E1275-80 pubmed 出版商

Zafarana G, Avery S, Avery K, Moore H, Andrews P. Specific knockdown of OCT4 in human embryonic stem cells by inducible short hairpin RNA interference. Stem Cells. 2009;27:776-82 pubmed 出版商

Chollangi S, Wang J, Martin A, Quinn J, Ash J. Preconditioning-induced protection from oxidative injury is mediated by leukemia inhibitory factor receptor (LIFR) and its ligands in the retina. Neurobiol Dis. 2009;34:535-44 pubmed 出版商

Scheel A, Beyer U, Agami R, Dobbelstein M. Immunofluorescence-based screening identifies germ cell associated microRNA 302 as an antagonist to p63 expression. Cell Cycle. 2009;8:1426-32 pubmed

Listov Saabye N, Jensen M, Kiehr B, Hansen E, Svendsen J, Lundby A, et al. MCF-7 human mammary adenocarcinoma cells exhibit augmented responses to human insulin on a collagen IV surface. J Appl Toxicol. 2009;29:470-7 pubmed 出版商

Berdnikovs S, Abdala Valencia H, McCary C, Somand M, Cole R, Garcia A, et al. Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitment. J Immunol. 2009;182:4395-405 pubmed 出版商

Fowler P, Flannigan S, Mathers A, Gillanders K, Lea R, Wood M, et al. Gene expression analysis of human fetal ovarian primordial follicle formation. J Clin Endocrinol Metab. 2009;94:1427-35 pubmed 出版商

Fink C, Weigel R, Fink L, Wilhelm J, Kliesch S, Zeiler M, et al. Claudin-11 is over-expressed and dislocated from the blood-testis barrier in Sertoli cells associated with testicular intraepithelial neoplasia in men. Histochem Cell Biol. 2009;131:755-64 pubmed 出版商

van Steensel L, Paridaens D, Schrijver B, Dingjan G, van Daele P, van Hagen P, et al. Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy. Invest Ophthalmol Vis Sci. 2009;50:3091-8 pubmed 出版商

Weinmann L, Höck J, Ivacevic T, Ohrt T, Mütze J, Schwille P, et al. Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell. 2009;136:496-507 pubmed 出版商

Chou T, Chen W, Lee A, Hung S, Shih N, Chen M. Clusterin silencing in human lung adenocarcinoma cells induces a mesenchymal-to-epithelial transition through modulating the ERK/Slug pathway. Cell Signal. 2009;21:704-11 pubmed 出版商

Park M, Oh H, York D. Enterostatin affects cyclic AMP and ERK signaling pathways to regulate Agouti-related protein (AgRP) expression. Peptides. 2009;30:181-90 pubmed 出版商

Reiss A, Carsons S, Anwar K, Rao S, Edelman S, Zhang H, et al. Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis Rheum. 2008;58:3675-83 pubmed 出版商

Lee K, Kim J, Seo J, Kim T, Im J, Baek I, et al. Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress. J Neurochem. 2009;108:165-75 pubmed 出版商

Hurtado A, Holmes K, Geistlinger T, Hutcheson I, Nicholson R, Brown M, et al. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature. 2008;456:663-6 pubmed 出版商

Devey L, Ferenbach D, Mohr E, Sangster K, Bellamy C, Hughes J, et al. Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism. Mol Ther. 2009;17:65-72 pubmed 出版商

Wurdinger T, Tannous B, Saydam O, Skog J, Grau S, Soutschek J, et al. miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell. 2008;14:382-93 pubmed 出版商

Ludwig T, Theissen S, Morton M, Caplan M. The cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase. J Biol Chem. 2008;283:35410-8 pubmed 出版商

Zhang J, Gao Z, Yin J, Quon M, Ye J. S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2. J Biol Chem. 2008;283:35375-82 pubmed 出版商

Diallo J, Betton B, Parent N, Péant B, Lessard L, Le Page C, et al. Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors. Br J Cancer. 2008;99:1613-22 pubmed 出版商

Kim T, Choi Y, Ko J, Hasty P. High-throughput knock-in coupling gene targeting with the HPRT minigene and Cre-mediated recombination. Genesis. 2008;46:732-7 pubmed 出版商

Ruckert F, Hennig M, Petraki C, Wehrum D, Distler M, Denz A, et al. Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma. Br J Cancer. 2008;99:1484-92 pubmed 出版商

Gao Z, Ye J. Inhibition of transcriptional activity of c-JUN by SIRT1. Biochem Biophys Res Commun. 2008;376:793-6 pubmed 出版商

Csiszar A, Labinskyy N, Perez V, Recchia F, Podlutsky A, Mukhopadhyay P, et al. Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol. 2008;295:H1882-94 pubmed 出版商

Olivares C, Bilotas M, Buquet R, Borghi M, Sueldo C, Tesone M, et al. Effects of a selective cyclooxygenase-2 inhibitor on endometrial epithelial cells from patients with endometriosis. Hum Reprod. 2008;23:2701-8 pubmed 出版商

Sher F, Rössler R, Brouwer N, Balasubramaniyan V, Boddeke E, Copray S. Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2. Stem Cells. 2008;26:2875-83 pubmed 出版商

Hoivik E, Aumo L, Aesoy R, Lillefosse H, Lewis A, Perrett R, et al. Deoxyribonucleic acid methylation controls cell type-specific expression of steroidogenic factor 1. Endocrinology. 2008;149:5599-609 pubmed 出版商

Gariboldi S, Palazzo M, Zanobbio L, Selleri S, Sommariva M, Sfondrini L, et al. Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4. J Immunol. 2008;181:2103-10 pubmed

Kranz D, Dohmesen C, Dobbelstein M. BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways. J Cell Biol. 2008;182:197-213 pubmed 出版商

Leon D, Albasanz J, Castillo C, Iglesias I, Martín M. Effect of chronic gestational treatment with the adenosine A1 receptor agonist R-phenylisopropyladenosine on metabotropic glutamate receptors/phospholipase C pathway in maternal and fetal brain. J Neurosci Res. 2008;86:3295-305 pubmed 出版商

Grimsey N, Narayan P, Dragunow M, Glass M. A novel high-throughput assay for the quantitative assessment of receptor trafficking. Clin Exp Pharmacol Physiol. 2008;35:1377-82 pubmed 出版商

Besteiro S, Bertrand Michel J, Lebrun M, Vial H, Dubremetz J. Lipidomic analysis of Toxoplasma gondii tachyzoites rhoptries: further insights into the role of cholesterol. Biochem J. 2008;415:87-96 pubmed 出版商

Ramljak S, Asif A, Armstrong V, Wrede A, Groschup M, Buschmann A, et al. Physiological role of the cellular prion protein (PrPc): protein profiling study in two cell culture systems. J Proteome Res. 2008;7:2681-95 pubmed 出版商

Sallmyr A, Tomkinson A, Rassool F. Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks. Blood. 2008;112:1413-23 pubmed 出版商

Wiechec E, Overgaard J, Hansen L. A fragile site within the HPC1 region at 1q25.3 affecting RGS16, RGSL1, and RGSL2 in human breast carcinomas. Genes Chromosomes Cancer. 2008;47:766-80 pubmed 出版商

Ouellet V, Zietarska M, Portelance L, Lafontaine J, Madore J, Puiffe M, et al. Characterization of three new serous epithelial ovarian cancer cell lines. BMC Cancer. 2008;8:152 pubmed 出版商

Zhang Y, Wang Y, Zhang X, Ge H, Arendt Nielsen L, Shao J, et al. Proteomic analysis of differential proteins related to the neuropathic pain and neuroprotection in the dorsal root ganglion following its chronic compression in rats. Exp Brain Res. 2008;189:199-209 pubmed 出版商

Ryeom S, Baek K, Rioth M, Lynch R, Zaslavsky A, Birsner A, et al. Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth. Cancer Cell. 2008;13:420-31 pubmed 出版商

Fowler P, Dorà N, McFerran H, Amezaga M, Miller D, Lea R, et al. In utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep. Mol Hum Reprod. 2008;14:269-80 pubmed 出版商

Hua S, Kallen C, Dhar R, Baquero M, Mason C, Russell B, et al. Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression. Mol Syst Biol. 2008;4:188 pubmed 出版商

Korpal M, Lee E, Hu G, Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem. 2008;283:14910-4 pubmed 出版商

Grimsey N, Goodfellow C, Scotter E, Dowie M, Glass M, Graham E. Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!. J Neurosci Methods. 2008;171:78-86 pubmed 出版商

Schmidt R, Beyer T, Bensch W, Qian Y, Lin A, Kowala M, et al. Secreted proprotein convertase subtilisin/kexin type 9 reduces both hepatic and extrahepatic low-density lipoprotein receptors in vivo. Biochem Biophys Res Commun. 2008;370:634-40 pubmed 出版商

Moreira J, Shen T, Ohlsson G, Gromov P, Gromova I, Celis J. A combined proteome and ultrastructural localization analysis of 14-3-3 proteins in transformed human amnion (AMA) cells: definition of a framework to study isoform-specific differences. Mol Cell Proteomics. 2008;7:1225-40 pubmed 出版商

Suzuki A, Sekiya S, Buscher D, Izpisua Belmonte J, Taniguchi H. Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression. Development. 2008;135:1589-95 pubmed 出版商

Wang L, Zhou G, Liu P, Song J, Liang Y, Yan X, et al. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci U S A. 2008;105:4826-31 pubmed 出版商

Shin Y, Joo C, Gack M, Lee H, Jung J. Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression. Cancer Res. 2008;68:1751-9 pubmed 出版商

Ungvari Z, Labinskyy N, Gupte S, Chander P, Edwards J, Csiszar A. Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol. 2008;294:H2121-8 pubmed 出版商

Kanan Y, Wicker L, Al Ubaidi M, Mandal N, Kasus Jacobi A. Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress. Invest Ophthalmol Vis Sci. 2008;49:1071-8 pubmed 出版商

Song P, Xie Z, Wu Y, Xu J, Dong Y, Zou M. Protein kinase Czeta-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells. J Biol Chem. 2008;283:12446-55 pubmed 出版商

Lee M, Ryu J, Piao S, Choi M, Kim H, Zhang L, et al. Efficient gene expression system using the RTP801 promoter in the corpus cavernosum of high-cholesterol diet-induced erectile dysfunction rats for gene therapy. J Sex Med. 2008;5:1355-64 pubmed 出版商

Park M, Lyons J, Oh H, Yu Y, Woltering E, Greenway F, et al. Enterostatin inhibition of angiogenesis: possible role of pAMPK and vascular endothelial growth factor A (VEGF-A). Int J Obes (Lond). 2008;32:922-9 pubmed 出版商

Havasi A, Li Z, Wang Z, Martin J, Botla V, Ruchalski K, et al. Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem. 2008;283:12305-13 pubmed 出版商

Baldán A, Gomes A, Ping P, Edwards P. Loss of ABCG1 results in chronic pulmonary inflammation. J Immunol. 2008;180:3560-8 pubmed

Sauer M, Bretz A, Beinoraviciute Kellner R, Beitzinger M, Burek C, Rosenwald A, et al. C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity. Nucleic Acids Res. 2008;36:1900-12 pubmed 出版商

Kump E, Ji J, Wernli M, Hausermann P, Erb P. Gli2 upregulates cFlip and renders basal cell carcinoma cells resistant to death ligand-mediated apoptosis. Oncogene. 2008;27:3856-64 pubmed 出版商

Brandsma C, Hylkema M, van der Strate B, Slebos D, Luinge M, Geerlings M, et al. Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?. Respir Res. 2008;9:17 pubmed 出版商

Gabriel G, Herwig A, Klenk H. Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus. PLoS Pathog. 2008;4:e11 pubmed 出版商

Shembade N, Harhaj N, Parvatiyar K, Copeland N, Jenkins N, Matesic L, et al. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nat Immunol. 2008;9:254-62 pubmed 出版商

Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, et al. CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1. Cancer Res. 2008;68:790-9 pubmed 出版商

Qian Z, Xuan B, Hong T, Yu D. The full-length protein encoded by human cytomegalovirus gene UL117 is required for the proper maturation of viral replication compartments. J Virol. 2008;82:3452-65 pubmed 出版商

Rapti M, Atkinson S, Lee M, Trim A, Moss M, Murphy G. The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition. Biochem J. 2008;411:433-9 pubmed 出版商

Wilson J, Yamamoto K, Marriott A, Hussain S, Sung P, Hoatlin M, et al. FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. Oncogene. 2008;27:3641-52 pubmed 出版商

Efklidou S, Bailey R, Field N, Noursadeghi M, Collins M. vFLIP from KSHV inhibits anoikis of primary endothelial cells. J Cell Sci. 2008;121:450-7 pubmed 出版商

Revet I, Huizenga G, Chan A, Koster J, Volckmann R, van Sluis P, et al. The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma. Exp Cell Res. 2008;314:707-19 pubmed 出版商

Lopez L, Riffle A, Pike S, Gardner D, Hogue B. Importance of conserved cysteine residues in the coronavirus envelope protein. J Virol. 2008;82:3000-10 pubmed 出版商

Qadir M, Kwok B, Dragowska W, To K, Le D, Bally M, et al. Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization. Breast Cancer Res Treat. 2008;112:389-403 pubmed 出版商

Huang D, Ding Y, Luo W, Bender S, Qian C, Kort E, et al. Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo. Cancer Res. 2008;68:81-8 pubmed 出版商

Buvinic S, Bravo Zehnder M, Boyer J, Huidobro Toro J, Gonzalez A. Nucleotide P2Y1 receptor regulates EGF receptor mitogenic signaling and expression in epithelial cells. J Cell Sci. 2007;120:4289-301 pubmed

Park S, Cheong C, Idoyaga J, Kim J, Choi J, Do Y, et al. Generation and application of new rat monoclonal antibodies against synthetic FLAG and OLLAS tags for improved immunodetection. J Immunol Methods. 2008;331:27-38 pubmed

Parborell F, Abramovich D, Tesone M. Intrabursal administration of the antiangiopoietin 1 antibody produces a delay in rat follicular development associated with an increase in ovarian apoptosis mediated by changes in the expression of BCL2 related genes. Biol Reprod. 2008;78:506-13 pubmed

Tada T, Simonetta A, Batterton M, Kinoshita M, Edbauer D, Sheng M. Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neurons. Curr Biol. 2007;17:1752-8 pubmed

Arechiga A, Bell B, Leverrier S, Weist B, Porter M, Wu Z, et al. A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J Immunol. 2007;179:5291-300 pubmed

Pasgaard T, Stankevicius E, Jørgensen M, Ostergaard L, Simonsen U, Frøbert O. Hyperoxia reduces basal release of nitric oxide and contracts porcine coronary arteries. Acta Physiol (Oxf). 2007;191:285-96 pubmed

Peluffo M, Stouffer R, Tesone M. Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum. Am J Physiol Endocrinol Metab. 2007;293:E1215-23 pubmed

Ostergaard L, Stankevicius E, Andersen M, Eskildsen Helmond Y, Ledet T, Mulvany M, et al. Diminished NO release in chronic hypoxic human endothelial cells. Am J Physiol Heart Circ Physiol. 2007;293:H2894-903 pubmed

Ye J, Gao Z, Yin J, He Q. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. Am J Physiol Endocrinol Metab. 2007;293:E1118-28 pubmed

Dvorak M, De Joussineau C, Carter D, Pisitkun T, Knepper M, Gamba G, et al. Thiazide diuretics directly induce osteoblast differentiation and mineralized nodule formation by interacting with a sodium chloride co-transporter in bone. J Am Soc Nephrol. 2007;18:2509-16 pubmed

Pascal V, Nathan N, Claudio E, Siebenlist U, Anderson S. NF-kappa B p50/p65 affects the frequency of Ly49 gene expression by NK cells. J Immunol. 2007;179:1751-9 pubmed

Hitz C, Wurst W, Kühn R. Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference. Nucleic Acids Res. 2007;35:e90 pubmed

Boehmerle W, Zhang K, Sivula M, Heidrich F, Lee Y, Jordt S, et al. Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. Proc Natl Acad Sci U S A. 2007;104:11103-8 pubmed

Wittlinger M, Grabenbauer G, Sprung C, Sauer R, Distel L. Time and dose-dependent activation of p53 serine 15 phosphorylation among cell lines with different radiation sensitivity. Int J Radiat Biol. 2007;83:245-57 pubmed

Mukoyama Y, Utani A, Matsui S, Zhou S, Miyachi Y, Matsuyoshi N. T-cadherin enhances cell-matrix adhesiveness by regulating beta1 integrin trafficking in cutaneous squamous carcinoma cells. Genes Cells. 2007;12:787-96 pubmed

Duan S, Yao Z, Hou D, Wu Z, Zhu W, Wu M. Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53. EMBO J. 2007;26:3062-74 pubmed

Mandrekar P, Jeliazkova V, Catalano D, Szabo G. Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes. J Immunol. 2007;178:7686-93 pubmed

Moerch U, Nielsen H, Lundsgaard D, Oleksiewicz M. Flow sorting from organ material by intracellular markers. Cytometry A. 2007;71:495-500 pubmed

Wergeland L, Sjøholt G, Haaland I, Hovland R, Bruserud Ø, Gjertsen B. Pre-apoptotic response to therapeutic DNA damage involves protein modulation of Mcl-1, Hdm2 and Flt3 in acute myeloid leukemia cells. Mol Cancer. 2007;6:33 pubmed

Bryja V, Gradl D, Schambony A, Arenas E, Schulte G. Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci U S A. 2007;104:6690-5 pubmed

Lewis P, Stefanovic N, Pete J, Calkin A, Giunti S, Thallas Bonke V, et al. Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E-deficient mice. Circulation. 2007;115:2178-87 pubmed

Zhou Y, Yau C, Gray J, Chew K, Dairkee S, Moore D, et al. Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer. BMC Cancer. 2007;7:59 pubmed

Planko L, Böhse K, Hohfeld J, Betz R, Hanneken S, Eigelshoven S, et al. Identification of a keratin-associated protein with a putative role in vesicle transport. Eur J Cell Biol. 2007;86:827-39 pubmed

Marx C, Yau C, Banwait S, Zhou Y, Scott G, Hann B, et al. Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer. Mol Pharmacol. 2007;71:1525-34 pubmed

Humar B, Fukuzawa R, Blair V, Dunbier A, More H, Charlton A, et al. Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. Cancer Res. 2007;67:2480-9 pubmed

Manfredi M, Ecsedy J, Meetze K, Balani S, Burenkova O, Chen W, et al. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc Natl Acad Sci U S A. 2007;104:4106-11 pubmed

Deem T, Abdala Valencia H, Cook Mills J. VCAM-1 activation of endothelial cell protein tyrosine phosphatase 1B. J Immunol. 2007;178:3865-73 pubmed

Clemitson J, Dixon R, Haines S, Bingham A, Patel B, Hall L, et al. Genetic dissection of a blood pressure quantitative trait locus on rat chromosome 1 and gene expression analysis identifies SPON1 as a novel candidate hypertension gene. Circ Res. 2007;100:992-9 pubmed

Cachard Chastel M, Lezoualc H F, Dewachter I, Delomenie C, Croes S, Devijver H, et al. 5-HT4 receptor agonists increase sAPPalpha levels in the cortex and hippocampus of male C57BL/6j mice. Br J Pharmacol. 2007;150:883-92 pubmed

Styblo M, Walton F, Harmon A, Sheridan P, Beck M. Activation of superoxide dismutase in selenium-deficient mice infected with influenza virus. J Trace Elem Med Biol. 2007;21:52-62 pubmed

Muylaert I, Elias P. Knockdown of DNA ligase IV/XRCC4 by RNA interference inhibits herpes simplex virus type I DNA replication. J Biol Chem. 2007;282:10865-72 pubmed

Tahir S, Yang X, Anderson M, Morgan Lappe S, Sarthy A, Chen J, et al. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res. 2007;67:1176-83 pubmed

Dhillon K, Sidorova J, Saintigny Y, Poot M, Gollahon K, Rabinovitch P, et al. Functional role of the Werner syndrome RecQ helicase in human fibroblasts. Aging Cell. 2007;6:53-61 pubmed

Larsen L, Tonnesen M, Ronn S, Størling J, Jørgensen S, Mascagni P, et al. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells. Diabetologia. 2007;50:779-89 pubmed

Thomson B, Ahrens J, Ntambi J, DeLuca H, Clagett Dame M. 2-Methylene-19-nor-1alpha-hydroxyvitamin D3 analogs inhibit adipocyte differentiation and PPARgamma2 gene transcription. Arch Biochem Biophys. 2007;460:192-201 pubmed

Wan H, Yuan M, Simpson C, Allen K, Gavins F, Ikram M, et al. Stem/progenitor cell-like properties of desmoglein 3dim cells in primary and immortalized keratinocyte lines. Stem Cells. 2007;25:1286-97 pubmed

Chan E, Zhang H, Fernandez P, Edelman S, Pillinger M, Ragolia L, et al. Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular risk. Arthritis Res Ther. 2007;9:R4 pubmed

Ungvari Z, Orosz Z, Rivera A, Labinskyy N, Xiangmin Z, Olson S, et al. Resveratrol increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol. 2007;292:H2417-24 pubmed

Lin J, Raoof D, Wang Z, Lin M, Thomas D, Greenson J, et al. Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma. Neoplasia. 2006;8:1062-71 pubmed

Recktenwald C, Mendler S, Lichtenfels R, Kellner R, Seliger B. Influence of Ki-ras-driven oncogenic transformation on the protein network of murine fibroblasts. Proteomics. 2007;7:385-98 pubmed

Seliger B, Fedorushchenko A, Brenner W, Ackermann A, Atkins D, Hanash S, et al. Ubiquitin COOH-terminal hydrolase 1: a biomarker of renal cell carcinoma associated with enhanced tumor cell proliferation and migration. Clin Cancer Res. 2007;13:27-37 pubmed

Troester M, Herschkowitz J, Oh D, He X, Hoadley K, Barbier C, et al. Gene expression patterns associated with p53 status in breast cancer. BMC Cancer. 2006;6:276 pubmed

Zheng D, Oh S, Jung Y, Petersen B. Oval cell response in 2-acetylaminofluorene/partial hepatectomy rat is attenuated by short interfering RNA targeted to stromal cell-derived factor-1. Am J Pathol. 2006;169:2066-74 pubmed

Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature. 2006;444:633-7 pubmed

Devoogdt N, Revets H, Kindt A, Liu Y, De Baetselier P, Ghassabeh G. The tumor-promoting effect of TNF-alpha involves the induction of secretory leukocyte protease inhibitor. J Immunol. 2006;177:8046-52 pubmed

Lopez Garcia J, Periyasamy M, Thomas R, Christian M, Leao M, Jat P, et al. ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases. Nucleic Acids Res. 2006;34:6126-36 pubmed

Carrel T, McWhorter M, Workman E, Zhang H, Wolstencroft E, Lorson C, et al. Survival motor neuron function in motor axons is independent of functions required for small nuclear ribonucleoprotein biogenesis. J Neurosci. 2006;26:11014-22 pubmed

Abdala Valencia H, Cook Mills J. VCAM-1 signals activate endothelial cell protein kinase Calpha via oxidation. J Immunol. 2006;177:6379-87 pubmed

Jones M, Fusi L, Higham J, Abdel Hafiz H, Horwitz K, Lam E, et al. Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Proc Natl Acad Sci U S A. 2006;103:16272-7 pubmed

Sun Wada G, Toyomura T, Murata Y, Yamamoto A, Futai M, Wada Y. The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells. J Cell Sci. 2006;119:4531-40 pubmed

Li W, Marshall C, Mei L, Gelfand J, Seykora J. Srcasm corrects Fyn-induced epidermal hyperplasia by kinase down-regulation. J Biol Chem. 2007;282:1161-9 pubmed

Bryja V, Schulte G, Arenas E. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell Signal. 2007;19:610-6 pubmed

Meijer J, Zeelenberg I, Sipos B, Roos E. The CXCR5 chemokine receptor is expressed by carcinoma cells and promotes growth of colon carcinoma in the liver. Cancer Res. 2006;66:9576-82 pubmed

Jiang P, Du W, Heese K, Wu M. The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis. Mol Cell Biol. 2006;26:9071-82 pubmed

Cronauer M, Ince Y, Engers R, Rinnab L, Weidemann W, Suschek C, et al. Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression. Oncogene. 2007;26:1875-84 pubmed

Dalkilic I, Schienda J, Thompson T, Kunkel L. Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure. Mol Cell Biol. 2006;26:6522-34 pubmed

Ukropec J, Anunciado R, Ravussin Y, Hulver M, Kozak L. UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice. J Biol Chem. 2006;281:31894-908 pubmed

Fernandez Twinn D, Ekizoglou S, Wayman A, Petry C, Ozanne S. Maternal low-protein diet programs cardiac beta-adrenergic response and signaling in 3-mo-old male offspring. Am J Physiol Regul Integr Comp Physiol. 2006;291:R429-36 pubmed

Weber P, Madsen Bouterse S, Rosa G, Sipkovsky S, Ren X, Almeida P, et al. Analysis of the bovine neutrophil transcriptome during glucocorticoid treatment. Physiol Genomics. 2006;28:97-112 pubmed

Lao D, Chandramouli S, Yusoff P, Fong C, Saw T, Tai L, et al. A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation. J Biol Chem. 2006;281:29993-30000 pubmed

Graham E, Ball N, Scotter E, Narayan P, Dragunow M, Glass M. Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway. J Biol Chem. 2006;281:29085-95 pubmed

Hurt E, Thomas S, Peng B, Farrar W. Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator. Cancer Biol Ther. 2006;5:1154-60 pubmed

Quarto N, Longaker M. FGF-2 inhibits osteogenesis in mouse adipose tissue-derived stromal cells and sustains their proliferative and osteogenic potential state. Tissue Eng. 2006;12:1405-18 pubmed

Sammons M, Wan S, Vogel N, Mientjes E, Grosveld G, Ashburner B. Negative regulation of the RelA/p65 transactivation function by the product of the DEK proto-oncogene. J Biol Chem. 2006;281:26802-12 pubmed

Anensen N, Oyan A, Bourdon J, Kalland K, Bruserud O, Gjertsen B. A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia. Clin Cancer Res. 2006;12:3985-92 pubmed

Aichem A, Masilamani M, Illges H. Redox regulation of CD21 shedding involves signaling via PKC and indicates the formation of a juxtamembrane stalk. J Cell Sci. 2006;119:2892-902 pubmed

Rickle A, Behbahani H, Ankarcrona M, Winblad B, Cowburn R. PTEN, Akt, and GSK3beta signalling in rat primary cortical neuronal cultures following tumor necrosis factor-alpha and trans-4-hydroxy-2-nonenal treatments. J Neurosci Res. 2006;84:596-605 pubmed

López A, Alegre E, Díaz A, Mugueta C, Gonzalez A. Bimodal effect of nitric oxide in the enzymatic activity of indoleamine 2,3-dioxygenase in human monocytic cells. Immunol Lett. 2006;106:163-71 pubmed

García Pedrero J, Kiskinis E, Parker M, Belandia B. The SWI/SNF chromatin remodeling subunit BAF57 is a critical regulator of estrogen receptor function in breast cancer cells. J Biol Chem. 2006;281:22656-64 pubmed

Sayama K, Hanakawa Y, Nagai H, Shirakata Y, Dai X, Hirakawa S, et al. Transforming growth factor-beta-activated kinase 1 is essential for differentiation and the prevention of apoptosis in epidermis. J Biol Chem. 2006;281:22013-20 pubmed

Koutsami M, Tsantoulis P, Kouloukoussa M, Apostolopoulou K, Pateras I, Spartinou Z, et al. Centrosome abnormalities are frequently observed in non-small-cell lung cancer and are associated with aneuploidy and cyclin E overexpression. J Pathol. 2006;209:512-21 pubmed

Chen S, Cai C, Fisher C, Zheng Z, Omwancha J, Hsieh C, et al. c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation. Oncogene. 2006;25:7212-23 pubmed

Madsen Bouterse S, Rosa G, Burton J. Glucocorticoid modulation of Bcl-2 family members A1 and Bak during delayed spontaneous apoptosis of bovine blood neutrophils. Endocrinology. 2006;147:3826-34 pubmed

Zeng B, Iravani M, Lin S, Irifune M, Kuoppamaki M, Al Barghouthy G, et al. MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome. Eur J Neurosci. 2006;23:1766-74 pubmed

Massey A, Kaushik S, Sovak G, Kiffin R, Cuervo A. Consequences of the selective blockage of chaperone-mediated autophagy. Proc Natl Acad Sci U S A. 2006;103:5805-10 pubmed

Andreassen A, Vikse R, Mikalsen A, Adamovic T, Steffensen I, Hjertholm H, et al. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces genetic changes in murine intestinal tumours and cells with ApcMin mutation. Mutat Res. 2006;604:60-70 pubmed

Ogawa D, Nomiyama T, Nakamachi T, Heywood E, Stone J, Berger J, et al. Activation of peroxisome proliferator-activated receptor gamma suppresses telomerase activity in vascular smooth muscle cells. Circ Res. 2006;98:e50-9 pubmed

Buvinic S, Poblete M, Donoso M, Delpiano A, Briones R, Miranda R, et al. P2Y1 and P2Y2 receptor distribution varies along the human placental vascular tree: role of nucleotides in vascular tone regulation. J Physiol. 2006;573:427-43 pubmed

Shaw L, Sadler A, Pugazhendhi D, Darbre P. Changes in oestrogen receptor-alpha and -beta during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells. J Steroid Biochem Mol Biol. 2006;99:19-32 pubmed

Rawal N, Castelo Branco G, Sousa K, Kele J, Kobayashi K, Okano H, et al. Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Exp Cell Res. 2006;312:1626-36 pubmed

Bloomfield F, Van Zijl P, Bauer M, Phua H, Harding J. Effect of pulsatile growth hormone administration to the growth-restricted fetal sheep on somatotrophic axis gene expression in fetal and placental tissues. Am J Physiol Endocrinol Metab. 2006;291:E333-9 pubmed

Chiba C, Hoshino A, Nakamura K, Susaki K, Yamano Y, Kaneko Y, et al. Visual cycle protein RPE65 persists in new retinal cells during retinal regeneration of adult newt. J Comp Neurol. 2006;495:391-407 pubmed

Betz R, Planko L, Eigelshoven S, Hanneken S, Pasternack S, Bussow H, et al. Loss-of-function mutations in the keratin 5 gene lead to Dowling-Degos disease. Am J Hum Genet. 2006;78:510-9 pubmed

Schumann M, Dobbelstein M. Adenovirus-induced extracellular signal-regulated kinase phosphorylation during the late phase of infection enhances viral protein levels and virus progeny. Cancer Res. 2006;66:1282-8 pubmed

Zhu T, Sennlaub F, Beauchamp M, Fan L, Joyal J, Checchin D, et al. Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent. Arterioscler Thromb Vasc Biol. 2006;26:744-50 pubmed

Quayle S, Sadar M. A truncated isoform of TMEFF2 encodes a secreted protein in prostate cancer cells. Genomics. 2006;87:633-7 pubmed

Tsuchihashi S, Ke B, Kaldas F, Flynn E, Busuttil R, Briscoe D, et al. Vascular endothelial growth factor antagonist modulates leukocyte trafficking and protects mouse livers against ischemia/reperfusion injury. Am J Pathol. 2006;168:695-705 pubmed

Schumann M, Dobbelstein M. Activating Ras mutations fail to ensure efficient replication of adenovirus mutants lacking VA-RNA. Cell Cycle. 2006;5:315-21 pubmed

Marks J, Srai S, Biber J, Murer H, Unwin R, Debnam E. Intestinal phosphate absorption and the effect of vitamin D: a comparison of rats with mice. Exp Physiol. 2006;91:531-7 pubmed

Ruchalski K, Mao H, Li Z, Wang Z, Gillers S, Wang Y, et al. Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation. J Biol Chem. 2006;281:7873-80 pubmed

Paquet Durand F, Azadi S, Hauck S, Ueffing M, van Veen T, Ekstrom P. Calpain is activated in degenerating photoreceptors in the rd1 mouse. J Neurochem. 2006;96:802-14 pubmed

Gao Z, He Q, Peng B, Chiao P, Ye J. Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function. J Biol Chem. 2006;281:4540-7 pubmed

Abuarqoub H, Foresti R, Green C, Motterlini R. Heme oxygenase-1 mediates the anti-inflammatory actions of 2'-hydroxychalcone in RAW 264.7 murine macrophages. Am J Physiol Cell Physiol. 2006;290:C1092-9 pubmed

Chen J, Ozanne S, Hales C. Analysis of expression of growth factor receptors in replicatively and oxidatively senescent human fibroblasts. FEBS Lett. 2005;579:6388-94 pubmed

Kaindl A, Sifringer M, Zabel C, Nebrich G, Wacker M, Felderhoff Mueser U, et al. Acute and long-term proteome changes induced by oxidative stress in the developing brain. Cell Death Differ. 2006;13:1097-109 pubmed

Egerod F, Nielsen H, Iversen L, Thorup I, Storgaard T, Oleksiewicz M. Biomarkers for early effects of carcinogenic dual-acting PPAR agonists in rat urinary bladder urothelium in vivo. Biomarkers. 2005;10:295-309 pubmed

Fan G, Qi C, Chen S. Heat shock proteins reduce toxicity of 1-methyl-4-phenylpyridinium ion in SK-N-SH cells. J Neurosci Res. 2005;82:551-62 pubmed

Lu H, Dalgard C, Mohyeldin A, McFate T, Tait A, Verma A. Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J Biol Chem. 2005;280:41928-39 pubmed

Beitzinger M, Oswald C, Beinoraviciute Kellner R, Stiewe T. Regulation of telomerase activity by the p53 family member p73. Oncogene. 2006;25:813-26 pubmed

Miller C, Lin L, Casper A, Lim J, Thomas D, Orringer M, et al. Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma. Oncogene. 2006;25:409-18 pubmed

Benn C, Landles C, Li H, Strand A, Woodman B, Sathasivam K, et al. Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease. Hum Mol Genet. 2005;14:3065-78 pubmed

Friedrich M, Wen B, Bain G, Kee B, Katayama C, Murre C, et al. DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. Int Immunol. 2005;17:1379-90 pubmed

Huang J, Tatsumi T, Pizzoferrato E, Vujanovic N, Storkus W. Nitric oxide sensitizes tumor cells to dendritic cell-mediated apoptosis, uptake, and cross-presentation. Cancer Res. 2005;65:8461-70 pubmed

Varela Nallar L, Toledo E, Larrondo L, Cabral A, Martins V, Inestrosa N. Induction of cellular prion protein gene expression by copper in neurons. Am J Physiol Cell Physiol. 2006;290:C271-81 pubmed

Medunjanin S, Hermani A, De Servi B, Grisouard J, Rincke G, Mayer D. Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity. J Biol Chem. 2005;280:33006-14 pubmed

Mazan Mamczarz K, Kawai T, Martindale J, Gorospe M. En masse analysis of nascent translation using microarrays. Biotechniques. 2005;39:61-2, 64, 66-7 pubmed

Yew K, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, et al. Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells. J Biol Chem. 2005;280:32209-17 pubmed

Gilbert J, Lang A, Nijland M. Maternal nutrient restriction and the fetal left ventricle: decreased angiotensin receptor expression. Reprod Biol Endocrinol. 2005;3:27 pubmed

Chen J, Ozanne S, Hales C. Heterogeneity in premature senescence by oxidative stress correlates with differential DNA damage during the cell cycle. DNA Repair (Amst). 2005;4:1140-8 pubmed

Shaikh S, Bloomfield F, Bauer M, Phua H, Gilmour R, Harding J. Amniotic IGF-I supplementation of growth-restricted fetal sheep alters IGF-I and IGF receptor type 1 mRNA and protein levels in placental and fetal tissues. J Endocrinol. 2005;186:145-55 pubmed

Matsui R, Xu S, Maitland K, Hayes A, Leopold J, Handy D, et al. Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II. Circulation. 2005;112:257-63 pubmed

Salahshor S, Goncalves J, Chetty R, Gallinger S, Woodgett J. Differential gene expression profile reveals deregulation of pregnancy specific beta1 glycoprotein 9 early during colorectal carcinogenesis. BMC Cancer. 2005;5:66 pubmed

Bertoja A, Zenclussen M, Wollenberg I, Paeschke S, Sollwedel A, Gerlof K, et al. Upregulation of Bcl-2 at the foetal-maternal interface from mice undergoing abortion. Scand J Immunol. 2005;61:492-502 pubmed

Barker K, Spendlove H, Banu N, Bridge J, Fisher C, Shipley J, et al. No evidence for epigenetic inactivation of fumarate hydratase in leiomyomas and leiomyosarcomas. Cancer Lett. 2006;235:136-40 pubmed

Gonzalez Santos J, Cao H, Wang A, Koehler D, Martin B, Navab R, et al. A complementation method for functional analysis of mammalian genes. Nucleic Acids Res. 2005;33:e94 pubmed

Corydon T, Hansen J, Bross P, Jensen T. Down-regulation of Hsp60 expression by RNAi impairs folding of medium-chain acyl-CoA dehydrogenase wild-type and disease-associated proteins. Mol Genet Metab. 2005;85:260-70 pubmed

D Souza T, Agarwal R, Morin P. Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells. J Biol Chem. 2005;280:26233-40 pubmed

Roncador G, Brown P, Maestre L, Hue S, Martinez Torrecuadrada J, Ling K, et al. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level. Eur J Immunol. 2005;35:1681-91 pubmed

Chien C, Liu T, Ho C, Lu K. Overexpression of neuronal intermediate filament protein alpha-internexin in PC12 cells. J Neurosci Res. 2005;80:693-706 pubmed

Rim J, Mynatt R, Gawronska Kozak B. Mesenchymal stem cells from the outer ear: a novel adult stem cell model system for the study of adipogenesis. FASEB J. 2005;19:1205-7 pubmed

Xiao J, Huang Y, Dai Z, Sadee W, Chen J, Liu S, et al. Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines. J Pharmacol Exp Ther. 2005;314:467-75 pubmed

Berry E, Keelan J, Helliwell R, Gilmour R, Mitchell M. Nanomolar and micromolar effects of 15-deoxy-delta 12,14-prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors gamma and delta and nuclear factor kappa B. Mol Pharmacol. 2005;68:169-78 pubmed

Gao Z, Chiao P, Zhang X, Zhang X, Lazar M, Seto E, et al. Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter. J Biol Chem. 2005;280:21091-8 pubmed

Murakami J, Asaumi J, Kawai N, Tsujigiwa H, Yanagi Y, Nagatsuka H, et al. Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer. Cancer Chemother Pharmacol. 2005;56:22-8 pubmed

Gilbert J, Lang A, Grant A, Nijland M. Maternal nutrient restriction in sheep: hypertension and decreased nephron number in offspring at 9 months of age. J Physiol. 2005;565:137-47 pubmed

Wang W, Jia L, Wang T, Sun W, Wu S, Wang X. Endogenous calcitonin gene-related peptide protects human alveolar epithelial cells through protein kinase Cepsilon and heat shock protein. J Biol Chem. 2005;280:20325-30 pubmed

Xu R, Peck R, Li D, Feng X, Ludwig T, Thomson J. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods. 2005;2:185-90 pubmed

Xie Q, Gao C, Shinomiya N, Sausville E, Hay R, Gustafson M, et al. Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion. Oncogene. 2005;24:3697-707 pubmed

Zhou J, Cai B, Jang Y, Pachydaki S, Schmidt A, Sparrow J. Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells. Exp Eye Res. 2005;80:567-80 pubmed

Battista M, Calvo E, Chorvatova A, Comte B, Corbeil J, Brochu M. Intra-uterine growth restriction and the programming of left ventricular remodelling in female rats. J Physiol. 2005;565:197-205 pubmed

Kamel Mohamed S, Sugiyama E, Shinoda K, Hounoki H, Taki H, Maruyama M, et al. Interleukin-4 inhibits RANKL-induced expression of NFATc1 and c-Fos: a possible mechanism for downregulation of osteoclastogenesis. Biochem Biophys Res Commun. 2005;329:839-45 pubmed

Tawfik V, Lacroix Fralish M, Nutile McMenemy N, DeLeo J. Transcriptional and translational regulation of glial activation by morphine in a rodent model of neuropathic pain. J Pharmacol Exp Ther. 2005;313:1239-47 pubmed

Tran T, Fernandes D, Schuliga M, Harris T, Landells L, Stewart A. Stimulus-dependent glucocorticoid-resistance of GM-CSF production in human cultured airway smooth muscle. Br J Pharmacol. 2005;145:123-31 pubmed

Minn A, Hafele C, Shalev A. Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis. Endocrinology. 2005;146:2397-405 pubmed

Zen Y, Harada K, Sasaki M, Chen T, Chen M, Yeh T, et al. Intrahepatic cholangiocarcinoma escapes from growth inhibitory effect of transforming growth factor-beta1 by overexpression of cyclin D1. Lab Invest. 2005;85:572-81 pubmed

Smith D, Bath M, Harris A, Cory S. T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haemopoietic expression of MYC. Oncogene. 2005;24:3544-53 pubmed

Bai S, He B, Wilson E. Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction. Mol Cell Biol. 2005;25:1238-57 pubmed

le Noble F, Fleury V, Pries A, Corvol P, Eichmann A, Reneman R. Control of arterial branching morphogenesis in embryogenesis: go with the flow. Cardiovasc Res. 2005;65:619-28 pubmed

Akhurst B, Matthews V, Husk K, Smyth M, Abraham L, Yeoh G. Differential lymphotoxin-beta and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury. Hepatology. 2005;41:327-35 pubmed

Cheng Z, Elmes M, Kirkup S, Chin E, Abayasekara D, Wathes D. The effect of a diet supplemented with the n-6 polyunsaturated fatty acid linoleic acid on prostaglandin production in early- and late-pregnant ewes. J Endocrinol. 2005;184:165-78 pubmed

Fuenzalida K, Aguilera M, Piderit D, Ramos P, Contador D, Quinones V, et al. Peroxisome proliferator-activated receptor gamma is a novel target of the nerve growth factor signaling pathway in PC12 cells. J Biol Chem. 2005;280:9604-9 pubmed

Grant M, Barber V, Griffiths H. The presence of ascorbate induces expression of brain derived neurotrophic factor in SH-SY5Y neuroblastoma cells after peroxide insult, which is associated with increased survival. Proteomics. 2005;5:534-40 pubmed

Yordy J, Moussa O, Pei H, Chaussabel D, Li R, Watson D. SP100 inhibits ETS1 activity in primary endothelial cells. Oncogene. 2005;24:916-31 pubmed

Zenclussen A, Sollwedel A, Bertoja A, Gerlof K, Zenclussen M, Woiciechowsky C, et al. Heme oxygenase as a therapeutic target in immunological pregnancy complications. Int Immunopharmacol. 2005;5:41-51 pubmed