产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗白细胞介素-6抗体
目录 :
ab6672
规格 :
200微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 免疫沉淀, 放射免疫分析法, 免疫组化-石蜡切片, 免疫组化-冰冻切片, dot blot, 抑制或激活实验
文章摘录数: 63
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:500; 图 7b
Bloniarz D, Adamczyk Grochala J, Lewinska A, Wnuk M. The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence. Aging (Albany NY). 2021;13:15833-15874 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4d
Zhang W, Li J, Yao H, Li T. Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6. Nanoscale Res Lett. 2021;16:89 pubmed 出版商
  • dot blot; 小鼠; 1:1000; 图 7c
Frenis K, Helmstädter J, Ruan Y, Schramm E, Kalinovic S, Kröller Schön S, et al. Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects. Basic Res Cardiol. 2021;116:31 pubmed 出版商
  • 免疫组化; 人类; 1:400; 图 1f
Rupert J, Narasimhan A, Jengelley D, Jiang Y, Liu J, Au E, et al. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia. J Exp Med. 2021;218: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 6e
Chang N, Yeh C, Lin Y, Kuo K, Fong I, Kounis N, et al. Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5d
Zhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, et al. Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke. Aging (Albany NY). 2021;13:3060-3079 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2b
Kiss B, Szántó M, Hegedus C, Antal D, Szödényi A, Márton J, et al. Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis. Exp Dermatol. 2020;29:79-85 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5a
Lai X, Deng Z, Zhu X, Chen Z. Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-κB signaling pathway mediated inflammatory response. Biosci Rep. 2019;39: pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5h
Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik Grayck E, et al. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS ONE. 2017;12:e0171219 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed 出版商
  • 免疫组化; 小鼠; 1.1 ug/ml; 图 7
Khalaj K, Luna R, de França M, de Oliveira W, Peixoto C, Tayade C. RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss. Oncotarget. 2016;7:72486-72502 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Shi K, Qian J, Qi L, Mao D, Chen Y, Zhu Y, et al. Atorvastatin antagonizes the visfatin-induced expression of inflammatory mediators via the upregulation of NF-?B activation in HCAECs. Oncol Lett. 2016;12:1438-1444 pubmed
  • 免疫组化; 大鼠; 1:100; 图 3
  • 免疫印迹; 大鼠; 图 4
Garcia P, Seiva F, Carniato A, de Mello Júnior W, Duran N, Macedo A, et al. Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA biological response modifier. BMC Cancer. 2016;16:422 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 图 1
Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 图 4
Holditch S, Schreiber C, Burnett J, Ikeda Y. Arterial Remodeling in B-Type Natriuretic Peptide Knock-Out Females. Sci Rep. 2016;6:25623 pubmed 出版商
  • 免疫印迹; pigs ; 1:1000; 图 4
Ganesan S, Reynolds C, Hollinger K, Pearce S, Gabler N, Baumgard L, et al. Twelve hours of heat stress induces inflammatory signaling in porcine skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2016;310:R1288-96 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Mishra V, DiAngelo S, Silveyra P. Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation. Biol Sex Differ. 2016;7:16 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Liu Z, Gan L, Chen Y, Luo D, Zhang Z, Cao W, et al. Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes. Sci Rep. 2016;6:21382 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5
  • 免疫印迹; 人类; 1:1000; 图 3
Zhao J, Wang L, Dong X, Hu X, Zhou L, Liu Q, et al. The c-Jun N-terminal kinase (JNK) pathway is activated in human interstitial cystitis (IC) and rat protamine sulfate induced cystitis. Sci Rep. 2016;6:19670 pubmed 出版商
  • 免疫组化; 小鼠; 图 6
Yeh C, Slavin S, Da J, Hsu I, Luo J, Xiao G, et al. Estrogen receptor α in cancer associated fibroblasts suppresses prostate cancer invasion via reducing CCL5, IL6 and macrophage infiltration in the tumor microenvironment. Mol Cancer. 2016;15:7 pubmed 出版商
  • 抑制或激活实验; 人类; 图 6
Zhao C, Zhang W, Zhao Y, Yang Y, Luo H, Ji G, et al. Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism. Sci Rep. 2016;6:19404 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 表 s4
Piraino F, Volpetti F, Watson C, Maerkl S. A Digital-Analog Microfluidic Platform for Patient-Centric Multiplexed Biomarker Diagnostics of Ultralow Volume Samples. ACS Nano. 2016;10:1699-710 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 5f
Manda K, Tripathi P, Hsi A, Ning J, Ruzinova M, Liapis H, et al. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence. Oncogene. 2016;35:3282-92 pubmed 出版商
  • 免疫组化; 人类
Wardill H, Logan R, Bowen J, Van Sebille Y, Gibson R. Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer. Support Care Cancer. 2016;24:1779-88 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1.0 ug/ml
Rao C, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, et al. Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model. Mol Carcinog. 2016;55:600-10 pubmed 出版商
Zhuang M, Ding X, Song W, Chen H, Guan H, Yu Y, et al. Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients. Aging (Albany NY). 2021;13:16667-16683 pubmed 出版商
Zhou T, Li S, Yang L, Xiang D. microRNA-363-3p reduces endothelial cell inflammatory responses in coronary heart disease via inactivation of the NOX4-dependent p38 MAPK axis. Aging (Albany NY). 2021;13:11061-11082 pubmed 出版商
Araújo L, Torquato B, da Silva C, Dos Reis Monteiro M, Dos Santos Martins A, da Silva M, et al. Renal expression of cytokines and chemokines in diabetic nephropathy. BMC Nephrol. 2020;21:308 pubmed 出版商
Kalinovic S, Oelze M, Kröller Schön S, Steven S, Vujacic Mirski K, Kvandová M, et al. Comparison of Mitochondrial Superoxide Detection Ex Vivo/In Vivo by mitoSOX HPLC Method with Classical Assays in Three Different Animal Models of Oxidative Stress. Antioxidants (Basel). 2019;8: pubmed 出版商
Liu Z, Easson G, Zhao J, Makki N, Ahituv N, Hilton M, et al. Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice. PLoS Genet. 2019;15:e1008096 pubmed 出版商
Morgan E, Macdonald A. Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1-NFκB-IL-6 signalling axis. PLoS Pathog. 2019;15:e1007835 pubmed 出版商
Ryan D, Paul B, Koziol J, ElShamy W. The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells. Breast Cancer Res. 2019;21:53 pubmed 出版商
Wang G, Tang L, Zhang X, Li Y. LncRNA DILC participates in rheumatoid arthritis by inducing apoptosis of fibroblast-like synoviocytes and down-regulating IL-6. Biosci Rep. 2019;39: pubmed 出版商
Peng C, Zou X, Xia W, Gao H, Li Z, Liu N, et al. Integrin αvβ6 plays a bi-directional regulation role between colon cancer cells and cancer-associated fibroblasts. Biosci Rep. 2018;38: pubmed 出版商
Gao F, Liu X, Shen Z, Jia X, He H, Gao J, et al. Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice. Front Physiol. 2018;9:939 pubmed 出版商
Murali B, Ren Q, Luo X, Faget D, Wang C, Johnson R, et al. Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss. Cancer Res. 2018;78:5618-5630 pubmed 出版商
Huo C, Hill P, Chew G, Neeson P, Halse H, Williams E, et al. High mammographic density in women is associated with protumor inflammation. Breast Cancer Res. 2018;20:92 pubmed 出版商
Zhao L, Chen S, Sherchan P, Ding Y, Zhao W, Guo Z, et al. Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice. J Neuroinflammation. 2018;15:215 pubmed 出版商
Farsky P, Hirata M, Arnoni R, Almeida A, Issa M, Lima P, et al. Persistent Inflammatory Activity in Blood Cells and Artery Tissue from Patients with Previous Bare Metal Stent. Arq Bras Cardiol. 2018;111:134-141 pubmed 出版商
Liu G, Zhang W. Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes. Braz J Med Biol Res. 2018;51:e6896 pubmed 出版商
Zhang K, Che S, Pan C, Su Z, Zheng S, Yang S, et al. The SHH/Gli axis regulates CD90-mediated liver cancer stem cell function by activating the IL6/JAK2 pathway. J Cell Mol Med. 2018;22:3679-3690 pubmed 出版商
Zanotto Filho A, Rajamanickam S, Loranc E, Masamsetti V, Gorthi A, Romero J, et al. Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells. Cancer Lett. 2018;425:101-115 pubmed 出版商
Wang X, Villar V, Tiu A, Upadhyay K, Cuevas S. Dopamine D2 receptor upregulates leptin and IL-6 in adipocytes. J Lipid Res. 2018;59:607-614 pubmed 出版商
Paish H, Kalson N, Smith G, Del Carpio Pons A, Baldock T, Smith N, et al. Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2. Am J Pathol. 2018;188:696-714 pubmed 出版商
Chen L, Liu C, Gao J, Xie Z, Chan L, Keating D, et al. Inhibition of Miro1 disturbs mitophagy and pancreatic ?-cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes. Oncotarget. 2017;8:90693-90705 pubmed 出版商
Wu S, Lu Q, Wang N, Zhang J, Liu Q, Gao M, et al. Cyclic stretch induced-retinal pigment epithelial cell apoptosis and cytokine changes. BMC Ophthalmol. 2017;17:208 pubmed 出版商
Yan F, Shen N, Pang J, Zhao N, Zhang Y, Bode A, et al. A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target. Leukemia. 2017;: pubmed 出版商
Omland S, Wettergren E, Mollerup S, Asplund M, Mourier T, Hansen A, et al. Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin. BMC Cancer. 2017;17:675 pubmed 出版商
Matsuzaki T, Akasaki Y, Olmer M, Alvarez Garcia O, Reixach N, Buxbaum J, et al. Transthyretin deposition promotes progression of osteoarthritis. Aging Cell. 2017;16:1313-1322 pubmed 出版商
Levin E, Diekmann H, Fischer D. Highly efficient transduction of primary adult CNS and PNS neurons. Sci Rep. 2016;6:38928 pubmed 出版商
Kim J, Lee E, Park J, Song Y, Kim J, Cho K. Patients with Rheumatoid Arthritis Show Altered Lipoprotein Profiles with Dysfunctional High-Density Lipoproteins that Can Exacerbate Inflammatory and Atherogenic Process. PLoS ONE. 2016;11:e0164564 pubmed 出版商
Tabatabaei P, Visse E, Bergström P, Brannstrom T, Siesjo P, Bergenheim A. Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study. J Neurooncol. 2017;131:83-92 pubmed 出版商
Tarry Adkins J, Fernandez Twinn D, Chen J, Hargreaves I, Neergheen V, Aiken C, et al. Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats. Dis Model Mech. 2016;9:1221-1229 pubmed
Li Y, Cui S, Sun S, Shi W, Song Z, Wang S, et al. Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice. Oncotarget. 2016;7:60446-60460 pubmed 出版商
Kim R, Kaushik N, Suh Y, Yoo K, Cui Y, Kim M, et al. Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer. Oncotarget. 2016;7:53430-53442 pubmed 出版商
Wang Z, Wu S, Liao J, Zhong L, Xing T, Fan J, et al. Interleukin-6 and rs1800796 locus single nucleotide polymorphisms in response to hypoxia/reoxygenation in hepatocytes. Int J Mol Med. 2016;38:192-200 pubmed 出版商
Xu D, Zhou P, Wang Y, Zhang L, Fu W, Ruan B, et al. Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway. Mol Cancer. 2016;15:40 pubmed 出版商
Guo J, Chen L, Luo N, Li C, Chen R, Qu X, et al. LPS/TLR4-mediated stromal cells acquire an invasive phenotype and are implicated in the pathogenesis of adenomyosis. Sci Rep. 2016;6:21416 pubmed 出版商
Roth J, Köhler D, Schneider M, Granja T, Rosenberger P. Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury. PLoS ONE. 2016;11:e0146930 pubmed 出版商
Lee E, Lee S, Kim J, Kim K, Yang S, Jeong K, et al. Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells. PLoS ONE. 2016;11:e0146463 pubmed 出版商
Pan D, Jiang C, Ma Z, Blonska M, You M, Lin X. MALT1 is required for EGFR-induced NF-?B activation and contributes to EGFR-driven lung cancer progression. Oncogene. 2016;35:919-28 pubmed 出版商
Lauritzen H, Brandauer J, Schjerling P, Koh H, Treebak J, Hirshman M, et al. Contraction and AICAR stimulate IL-6 vesicle depletion from skeletal muscle fibers in vivo. Diabetes. 2013;62:3081-92 pubmed 出版商
Warren C, Li Y, Calabrese G, Freire R, Zaja Milatovic S, van Opstal E, et al. Contribution of adenosine A(2B) receptors in Clostridium difficile intoxication and infection. Infect Immun. 2012;80:4463-73 pubmed 出版商
产品信息
目录号 :
ab6672
ItemName :
抗白细胞介素-6抗体
产品类型 :
抗体
宿主物种 :
克隆性 :
多克隆
共轭标签 :
未共轭
规格 :
200微升
物种摘要 :
Hu, Ms, Pig, Rat
纯度 :
Whole antiserum
应用摘要 :
ELISA, ICC/IF, IHC-Fr, IHC-P, IP, Neut, RIA, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。