产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗STAT3(磷酸化Y705)抗体[EP2147Y]
目录 :
ab76315
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
EP2147Y
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, dot blot
文章摘录数: 54
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 图 7b
  • 免疫印迹; 人类; 图 4b
Ding H, Zhang X, Su Y, Jia C, Dai C. GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation. Cell Mol Biol Lett. 2020;25:8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 5a
Yang L, Shen L, Gao P, Li G, He Y, Wang M, et al. Effect of AMPK signal pathway on pathogenesis of abdominal aortic aneurysms. Oncotarget. 2017;8:92827-92840 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1f
Chi H, Chen S, Tsai C, Chuang W, Huang Y, Tsai M, et al. Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy. Autophagy. 2016;12:2271-2285 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 1
Mao S, Li X, Wang J, Ding X, Zhang C, Li L. miR-17-92 facilitates neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions. J Neuroinflammation. 2016;13:208 pubmed 出版商
  • 免疫印迹; 人类; 1:20,0000; 图 4
Liu Y, Wang Y, Ding G, Yang T, Yao L, Hua J, et al. JAK2 inhibitor combined with DC-activated AFP-specific T-cells enhances antitumor function in a Fas/FasL signal-independent pathway. Onco Targets Ther. 2016;9:4425-33 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
  • 免疫印迹; 人类; 图 3
Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed 出版商
  • 免疫印迹; 人类; 图 4f
Jiang C, Yu J, Ruan Y, Wang X, Zhao W, Wang X, et al. LIM domain only 2 over-expression in prostate stromal cells facilitates prostate cancer progression through paracrine of Interleukin-11. Oncotarget. 2016;7:26247-58 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Huang Y, Chen C, Tang K, Sheen J, Tiao M, Tain Y, et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci. 2016;17:369 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Mishra V, DiAngelo S, Silveyra P. Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation. Biol Sex Differ. 2016;7:16 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4a
Wang S, Zhou J, Kang W, Dong Z, Wang H. Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model. Bosn J Basic Med Sci. 2016;16:145-50 pubmed 出版商
  • 免疫印迹; 小鼠
Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Andersson K, Brisslert M, Cavallini N, Svensson M, Welin A, Erlandsson M, et al. Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6. Oncotarget. 2015;6:20043-57 pubmed
  • 免疫印迹; 人类
Yang N, Han F, Cui H, Huang J, Wang T, Zhou Y, et al. Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling. Pharmacol Rep. 2015;67:388-93 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
  • 免疫印迹; 小鼠; 1:1000
Huang S, Zou X, Zhu J, Fu Y, Lin Q, Liang Y, et al. Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy. J Cell Mol Med. 2015;19:608-19 pubmed 出版商
  • 免疫印迹; 人类
Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al. Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed 出版商
  • 免疫印迹; 人类
Chen R, Xu B, Chen S, Chen S, Zhang T, Ren J, et al. Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells. World J Gastroenterol. 2014;20:14895-903 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
McGuckin C, Jurga M, Miller A, Sarnowska A, Wiedner M, Boyle N, et al. Ischemic brain injury: a consortium analysis of key factors involved in mesenchymal stem cell-mediated inflammatory reduction. Arch Biochem Biophys. 2013;534:88-97 pubmed 出版商
Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, et al. miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis. Aging (Albany NY). 2021;13:19760-19775 pubmed 出版商
Zhuang M, Ding X, Song W, Chen H, Guan H, Yu Y, et al. Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients. Aging (Albany NY). 2021;13:16667-16683 pubmed 出版商
Lu H, Hsu H, Li C, Li S, Lin S, Shih C, et al. Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway. Antioxidants (Basel). 2021;10: pubmed 出版商
Wang L, Choi H, Lee B, Choi J, Jang Y, Seo J. 13R,20-Dihydroxydocosahexaenoic Acid, a Novel Dihydroxy- DHA Derivative, Inhibits Breast Cancer Stemness through Regulation of the Stat3/IL-6 Signaling Pathway by Inducing ROS Production. Antioxidants (Basel). 2021;10: pubmed 出版商
Cheng G, Liu Y, Liu L, Ruan H, Cao Q, Song Z, et al. LINC00160 mediates sunitinib resistance in renal cell carcinoma via SAA1 that is implicated in STAT3 activation and compound transportation. Aging (Albany NY). 2020;12:17459-17479 pubmed 出版商
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, et al. The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma. Aging (Albany NY). 2020;12:14391-14405 pubmed 出版商
Yao K, He L, Gan Y, Liu J, Tang J, Long Z, et al. HMGN5 promotes IL-6-induced epithelial-mesenchymal transition of bladder cancer by interacting with Hsp27. Aging (Albany NY). 2020;12:7282-7298 pubmed 出版商
Hu D, Chen H, Lou L, Zhang H, Yang G. SKA3 promotes lung adenocarcinoma metastasis through the EGFR-PI3K-Akt axis. Biosci Rep. 2020;40: pubmed 出版商
Krebs M, Behrmann C, Kalogirou C, Sokolakis I, Kneitz S, Kruithof de Julio M, et al. miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1. Biomed Res Int. 2019;2019:6392748 pubmed 出版商
Muromoto R, Tawa K, Ohgakiuchi Y, Sato A, Saino Y, Hirashima K, et al. IκB-ζ Expression Requires Both TYK2/STAT3 Activity and IL-17-Regulated mRNA Stabilization. Immunohorizons. 2019;3:172-185 pubmed 出版商
Cheng Y, Li S, Chuang W, Li C, Chen G, Chang C, et al. Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells. Int J Mol Sci. 2019;20: pubmed 出版商
Wang M, Fer N, Galeas J, Collisson E, Kim S, Sharib J, et al. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer. Nat Commun. 2019;10:3055 pubmed 出版商
Soutto M, Chen Z, Bhat A, Wang L, Zhu S, Gomaa A, et al. Activation of STAT3 signaling is mediated by TFF1 silencing in gastric neoplasia. Nat Commun. 2019;10:3039 pubmed 出版商
Han Y, Wu J, Yang W, Wang D, Zhang T, Cheng M. New STAT3-FOXL2 pathway and its function in cancer cells. BMC Mol Cell Biol. 2019;20:17 pubmed 出版商
Lee J, Chang J, Dominguez A, Lee H, Nam S, Chang J, et al. YAP-independent mechanotransduction drives breast cancer progression. Nat Commun. 2019;10:1848 pubmed 出版商
Xu J, Wang H, Wang H, Chen Q, Zhang L, Song C, et al. The inhibition of miR-126 in cell migration and invasion of cervical cancer through regulating ZEB1. Hereditas. 2019;156:11 pubmed 出版商
Dolatabadi S, Jonasson E, Lindén M, Fereydouni B, Bäcksten K, Nilsson M, et al. JAK-STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma. Int J Cancer. 2019;145:435-449 pubmed 出版商
Jin Z, Li H, Hong X, Ying G, Lu X, Zhuang L, et al. TRIM14 promotes colorectal cancer cell migration and invasion through the SPHK1/STAT3 pathway. Cancer Cell Int. 2018;18:202 pubmed 出版商
Song D, Kim D, Jung J, Nam S, Kim J, Kim H, et al. Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis. Front Pharmacol. 2018;9:1337 pubmed 出版商
Disson O, Blériot C, Jacob J, Serafini N, Dulauroy S, Jouvion G, et al. Peyer's patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion. J Exp Med. 2018;215:2936-2954 pubmed 出版商
Chen K, Fan J, Luo Z, Yang Y, Xin W, Liu C. Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib. J Neuroinflammation. 2018;15:292 pubmed 出版商
Kain D, Simon A, Greenberg A, Ben Zvi D, Gilburd B, Schneiderman J. Cardiac leptin overexpression in the context of acute MI and reperfusion potentiates myocardial remodeling and left ventricular dysfunction. PLoS ONE. 2018;13:e0203902 pubmed 出版商
Schulz Heddergott R, Stark N, Edmunds S, Li J, Conradi L, Bohnenberger H, et al. Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion. Cancer Cell. 2018;34:298-314.e7 pubmed 出版商
Bhat A, Lu H, Soutto M, Capobianco A, Rai P, Zaika A, et al. Exposure of Barrett's and esophageal adenocarcinoma cells to bile acids activates EGFR-STAT3 signaling axis via induction of APE1. Oncogene. 2018;37:6011-6024 pubmed 出版商
Chen K, Sun Y, Diao Y, Zhang T, Dong W. Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway. Oncol Lett. 2018;16:167-178 pubmed 出版商
Matsumoto L, Hirota Y, Saito Fujita T, Takeda N, Tanaka T, Hiraoka T, et al. HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment. J Clin Invest. 2018;128:3186-3197 pubmed 出版商
Zhang K, Che S, Pan C, Su Z, Zheng S, Yang S, et al. The SHH/Gli axis regulates CD90-mediated liver cancer stem cell function by activating the IL6/JAK2 pathway. J Cell Mol Med. 2018;22:3679-3690 pubmed 出版商
Teratani T, Tomita K, Suzuki T, Furuhashi H, Irie R, Nishikawa M, et al. Aortic carboxypeptidase-like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis. J Clin Invest. 2018;128:1581-1596 pubmed 出版商
Lei Z, Duan H, Zhao T, Zhang Y, Li G, Meng J, et al. PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway. Cell Death Dis. 2018;9:375 pubmed 出版商
Wang R, Zhao X, Xu J, Wen Y, Li A, Lu M, et al. Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice. Cell Death Dis. 2018;9:352 pubmed 出版商
Yu J, Wu H, Liu Z, Zhu Q, Shan C, Zhang K. Advanced glycation end products induce the apoptosis of and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation. Int J Mol Med. 2017;40:1185-1193 pubmed 出版商
Wang Z, Fan P, Zhao Y, Zhang S, Lu J, Xie W, et al. NEAT1 modulates herpes simplex virus-1 replication by regulating viral gene transcription. Cell Mol Life Sci. 2017;74:1117-1131 pubmed 出版商
Liu F, Zong M, Wen X, Li X, Wang J, Wang Y, et al. Silencing of Histone Deacetylase 9 Expression in Podocytes Attenuates Kidney Injury in Diabetic Nephropathy. Sci Rep. 2016;6:33676 pubmed 出版商
Kong X, Wu W, Yuan Y, Pandey V, Wu Z, Lu X, et al. Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma. Oncotarget. 2016;7:29465-79 pubmed 出版商
Ball D, Lewis A, Williams D, Resetca D, Wilson D, Gunning P. Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent. Oncotarget. 2016;7:20669-79 pubmed 出版商
Jing X, Ou C, Chen H, Wang T, Xu B, Lu S, et al. Electroacupuncture Reduces Weight Gain Induced by Rosiglitazone through PPARγ and Leptin Receptor in CNS. Evid Based Complement Alternat Med. 2016;2016:8098561 pubmed 出版商
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, et al. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nat Cell Biol. 2015;17:1523-35 pubmed 出版商
产品信息
目录号 :
ab76315
ItemName :
抗STAT3(磷酸化Y705)抗体[EP2147Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP2147Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
Dot, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。