产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗IRF3(磷酸化S386)抗体[EPR2346]
目录 :
ab76493
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EPR2346
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, dot blot
文章摘录数: 28
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2a, 2d
Groelly F, Porru M, Zimmer J, Benainous H, De Visser Y, Kosova A, et al. Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours. EMBO Mol Med. 2022;14:e14501 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 s8
Lu M, Zhang Z, Xue M, Zhao B, Harder O, Li A, et al. N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I. Nat Microbiol. 2020;5:584-598 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5d
Reisländer T, Lombardi E, Groelly F, Miar A, Porru M, Di Vito S, et al. BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors. Nat Commun. 2019;10:3143 pubmed 出版商
  • 免疫印迹; 人类; 图 s2e
Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 1b
Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell S, et al. A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Dai J, Huang Y, He X, Zhao M, Wang X, Liu Z, et al. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity. Cell. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 3
Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Meyerson N, Zhou L, Guo Y, Zhao C, Tao Y, Krug R, et al. Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. Cell Host Microbe. 2017;22:627-638.e7 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Lin T, Cheng C, Su H, Huang N, Chen J, Kang H, et al. Lipopolysaccharide Attenuates Induction of Proallergic Cytokines, Thymic Stromal Lymphopoietin, and Interleukin 33 in Respiratory Epithelial Cells Stimulated with PolyI:C and Human Parechovirus. Front Immunol. 2016;7:440 pubmed
  • 免疫细胞化学; 小鼠; 1:500; 图 3
  • 免疫印迹; 小鼠; 1:5000; 图 5
  • 免疫印迹; 人类; 1:5000; 图 5
Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Huang L, Stuart C, Takeda K, D Agnillo F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Sanchez David R, Combredet C, Sismeiro O, Dillies M, Jagla B, Coppée J, et al. Comparative analysis of viral RNA signatures on different RIG-I-like receptors. elife. 2016;5:e11275 pubmed 出版商
  • 免疫印迹; 人类; 图 s1i
Miller M, Rialdi A, Ho J, Tilove M, Martínez Gil L, Moshkina N, et al. Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. Nat Immunol. 2015;16:485-94 pubmed 出版商
Pallett M, Lu Y, Smith G. DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation. Viruses. 2022;14: pubmed 出版商
Chen Q, Ma K, Liu X, Chen S, Li P, Yu Y, et al. Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis. Cell Discov. 2022;8:3 pubmed 出版商
Khan H, Sumner R, Rasaiyaah J, Tan C, Rodriguez Plata M, Van Tulleken C, et al. HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport. elife. 2020;9: pubmed 出版商
Zhao Y, Ye X, Dunker W, Song Y, Karijolich J. RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection. Nat Commun. 2018;9:4841 pubmed 出版商
Yang Q, Tang J, Pei R, Gao X, Guo J, Xu C, et al. Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3. J Mol Cell Biol. 2019;11:158-169 pubmed 出版商
DERY K, Silver C, Yang L, Shively J. Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1. J Biol Chem. 2018;293:9277-9291 pubmed 出版商
Tian J, Liu Y, Liu X, Sun X, Zhang J, Qu L. Feline Herpesvirus 1 US3 Blocks the Type I Interferon Signal Pathway by Targeting Interferon Regulatory Factor 3 Dimerization in a Kinase-Independent Manner. J Virol. 2018;92: pubmed 出版商
Stabell A, Meyerson N, Gullberg R, Gilchrist A, Webb K, Old W, et al. Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir. elife. 2018;7: pubmed 出版商
Hu X, Tian J, Kang H, Guo D, Liu J, Liu D, et al. Transmissible Gastroenteritis Virus Papain-Like Protease 1 Antagonizes Production of Interferon-? through Its Deubiquitinase Activity. Biomed Res Int. 2017;2017:7089091 pubmed 出版商
Yuan L, Mao Y, Luo W, Wu W, Xu H, Wang X, et al. Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism. J Biol Chem. 2017;292:15002-15015 pubmed 出版商
Tsai P, Liu Y, Lin K, Liu Y, Liao Y, Hsiao C, et al. Mutational analysis of TBK1 in Taiwanese patients with amyotrophic lateral sclerosis. Neurobiol Aging. 2016;40:191.e11-191.e16 pubmed 出版商
Yuan M, Xu Y, Chen L, Li X, Qin J, Shen Y. TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis. BMC Cancer. 2015;15:245 pubmed 出版商
Lin L, Pan S, Zhao J, Liu C, Wang P, Fu L, et al. HSPD1 interacts with IRF3 to facilitate interferon-beta induction. PLoS ONE. 2014;9:e114874 pubmed 出版商
Schoggins J, MacDuff D, Imanaka N, Gainey M, Shrestha B, Eitson J, et al. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 2014;505:691-5 pubmed 出版商
Fichorova R, Lee Y, Yamamoto H, Takagi Y, Hayes G, Goodman R, et al. Endobiont viruses sensed by the human host - beyond conventional antiparasitic therapy. PLoS ONE. 2012;7:e48418 pubmed 出版商
产品信息
目录号 :
ab76493
ItemName :
抗IRF3(磷酸化S386)抗体[EPR2346]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EPR2346
规格 :
10微升, 100微升
物种摘要 :
Hu
应用摘要 :
Dot, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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