出版应用/物种/样本/稀释 | 参考文献 |
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| Mahata T, Sengar A, Basak M, Das K, Pramanick A, Verma S, et al. Hepatic Regulator of G Protein Signaling 6 (RGS6) drives non-alcoholic fatty liver disease by promoting oxidative stress and ATM-dependent cell death. Redox Biol. 2021;46:102105 pubmed 出版商
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| Waseem S, Kumar S, Lee K, Yoon B, Kim M, Kim H, et al. Protein Arginine Methyltransferase 1 Is Essential for the Meiosis of Male Germ Cells. Int J Mol Sci. 2021;22: pubmed 出版商
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- 免疫印迹; 人类; 1:800; 图 s6a
- 免疫印迹; 小鼠; 1:800; 图 6d
| Pramanick A, Chakraborti S, Mahata T, Basak M, Das K, Verma S, et al. G protein β5-ATM complexes drive acetaminophen-induced hepatotoxicity. Redox Biol. 2021;43:101965 pubmed 出版商
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| Collin G, Huna A, Warnier M, Flaman J, Bernard D. Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence. Cell Death Dis. 2018;9:259 pubmed 出版商
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| Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed 出版商
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| Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed 出版商
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- 免疫印迹基因敲除验证; 人类; 1:1000; 图 6b
| Schmid Burgk J, Höning K, Ebert T, Hornung V. CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. Nat Commun. 2016;7:12338 pubmed 出版商
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| Lin L, Swerdel M, Lazaropoulos M, Hoffman G, Toro Ramos A, Wright J, et al. Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. Stem Cell Reports. 2015;5:1097-1108 pubmed 出版商
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- 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 s1
| Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld F, et al. Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition. Nat Commun. 2015;6:7677 pubmed 出版商
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| Yu H, Xie J, Li B, Sun Y, Gao Q, Ding Z, et al. TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway. Sci Rep. 2015;5:9853 pubmed 出版商
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| Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed 出版商
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| Kawasumi M, Bradner J, Tolliday N, Thibodeau R, Sloan H, Brummond K, et al. Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity. Cancer Res. 2014;74:7534-45 pubmed 出版商
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| Ferlazzo M, Sonzogni L, Granzotto A, Bodgi L, Lartin O, Devic C, et al. Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates. Mol Neurobiol. 2014;49:1200-11 pubmed 出版商
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| Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013;12:3770-80 pubmed 出版商
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| Shamma A, Suzuki M, Hayashi N, Kobayashi M, Sasaki N, Nishiuchi T, et al. ATM mediates pRB function to control DNMT1 protein stability and DNA methylation. Mol Cell Biol. 2013;33:3113-24 pubmed 出版商
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| Sappino A, Buser R, Seguin Q, Fernet M, Lesne L, Gumy Pause F, et al. The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage. Oncogenesis. 2012;1:e7 pubmed 出版商
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| Singh K, Shukla P, Quan A, Desjardins J, Lovren F, Pan Y, et al. BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure. J Biol Chem. 2012;287:6604-14 pubmed 出版商
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| Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. elife. 2018;7: pubmed 出版商
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| Staples C, Barone G, Myers K, Ganesh A, Gibbs Seymour I, Patil A, et al. MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response. Cell Rep. 2016;16:2565-2575 pubmed 出版商
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| Ueno K, Takeuchi Y, Samura M, Tanaka Y, Nakamura T, Nishimoto A, et al. Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts. Sci Rep. 2016;6:28538 pubmed 出版商
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| Salzman D, Nakamura K, Nallur S, Dookwah M, Metheetrairut C, Slack F, et al. miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Nat Commun. 2016;7:10954 pubmed 出版商
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| Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed 出版商
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| Tengku Ahmad T, Jaafar F, Jubri Z, Abdul Rahim K, Rajab N, Makpol S. Gelam honey attenuated radiation-induced cell death in human diploid fibroblasts by promoting cell cycle progression and inhibiting apoptosis. BMC Complement Altern Med. 2014;14:108 pubmed 出版商
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| Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商
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| Edwards T, Helmus M, Koeller K, Bashkin J, Fisher C. Human papillomavirus episome stability is reduced by aphidicolin and controlled by DNA damage response pathways. J Virol. 2013;87:3979-89 pubmed 出版商
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| Sabatel H, Di Valentin E, Gloire G, Dequiedt F, Piette J, Habraken Y. Phosphorylation of p65(RelA) on Ser(547) by ATM represses NF-?B-dependent transcription of specific genes after genotoxic stress. PLoS ONE. 2012;7:e38246 pubmed 出版商
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| Shin J, Lee C, Lee K, Lee J, Lee K, Kim K, et al. Prognostic significance of ATM and cyclin B1 in pancreatic neuroendocrine tumor. Tumour Biol. 2012;33:1645-51 pubmed 出版商
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| Lee J, Sung C, Lee E, Do I, Kim H, Yoon S, et al. Metastasis of neuroendocrine tumors are characterized by increased cell proliferation and reduced expression of the ATM gene. PLoS ONE. 2012;7:e34456 pubmed 出版商
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| Wysham W, Mhawech Fauceglia P, Li H, Hays L, Syriac S, Skrepnik T, et al. BRCAness profile of sporadic ovarian cancer predicts disease recurrence. PLoS ONE. 2012;7:e30042 pubmed 出版商
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| Min J, Choi E, Hwang K, Kim J, Sampath S, Venkitaraman A, et al. The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis. J Biol Chem. 2012;287:5091-101 pubmed 出版商
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| Demuth I, Dutrannoy V, Marques W, Neitzel H, Schindler D, Dimova P, et al. New mutations in the ATM gene and clinical data of 25 AT patients. Neurogenetics. 2011;12:273-82 pubmed 出版商
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| Zhang W, Peng G, Lin S, Zhang P. DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells. J Biol Chem. 2011;286:35899-905 pubmed 出版商
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| Urcuqui Inchima S, Patiño C, Zapata X, García M, Arteaga J, Chamot C, et al. Production of HIV particles is regulated by altering sub-cellular localization and dynamics of Rev induced by double-strand RNA binding protein. PLoS ONE. 2011;6:e16686 pubmed 出版商
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| Vonlaufen N, Naguleswaran A, Coppens I, Sullivan W. MYST family lysine acetyltransferase facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii. J Biol Chem. 2010;285:11154-61 pubmed 出版商
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| Mattiussi S, Lazzari C, Truffa S, Antonini A, Soddu S, Capogrossi M, et al. Homeodomain interacting protein kinase 2 activation compromises endothelial cell response to laminar flow: protective role of p21(waf1,cip1,sdi1). PLoS ONE. 2009;4:e6603 pubmed 出版商
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| Winter M, Sombroek D, Dauth I, Moehlenbrink J, Scheuermann K, Crone J, et al. Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR. Nat Cell Biol. 2008;10:812-24 pubmed 出版商
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| Gastaldo J, Viau M, Bencokova Z, Joubert A, Charvet A, Balosso J, et al. Lead contamination results in late and slowly repairable DNA double-strand breaks and impacts upon the ATM-dependent signaling pathways. Toxicol Lett. 2007;173:201-14 pubmed
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| O Brien E, Barnes V, Zhao L, McKnight R, Yu X, Callaway C, et al. Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs. Am J Physiol Regul Integr Comp Physiol. 2007;293:R314-22 pubmed
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| Kozlov S, Graham M, Peng C, Chen P, Robinson P, Lavin M. Involvement of novel autophosphorylation sites in ATM activation. EMBO J. 2006;25:3504-14 pubmed
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| Gumy Pause F, Wacker P, Maillet P, Betts D, Sappino A. ATM alterations in childhood non-Hodgkin lymphoma. Cancer Genet Cytogenet. 2006;166:101-11 pubmed
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| Coll Mulet L, Iglesias Serret D, Santidrian A, Cosialls A, de Frias M, Castaño E, et al. MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells. Blood. 2006;107:4109-14 pubmed
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