产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗突触素抗体[SY38]
目录 :
ab8049
规格 :
1毫克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SY38
反应物种 :
人类, 小鼠, 大鼠, , pigs , 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 79
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 猕猴; 1:10; 图 8a
Maximova O, Sturdevant D, Kash J, Kanakabandi K, Xiao Y, Minai M, et al. Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses. elife. 2021;10: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2a
Griffin P, Sheehan P, Dimitry J, Guo C, Kanan M, Lee J, et al. REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 2a
Gulyassy P, Puska G, Györffy B, Todorov Völgyi K, Juhasz G, Drahos L, et al. Proteomic comparison of different synaptosome preparation procedures. Amino Acids. 2020;52:1529-1543 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 s7j
Dias D, Kim H, Holl D, Werne Solnestam B, Lundeberg J, Carlen M, et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell. 2018;173:153-165.e22 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 2
Loss O, Stephenson F. Developmental changes in trak-mediated mitochondrial transport in neurons. Mol Cell Neurosci. 2017;80:134-147 pubmed 出版商
  • 免疫组化; 大鼠; 1:200; 表 2
Han Q, Lin Q, Huang P, Chen M, Hu X, Fu H, et al. Microglia-derived IL-1? contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats. J Neuroinflammation. 2017;14:52 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:500; 图 5a
  • 免疫印迹; 大鼠; 图 5b
Zhu Y, Zhang Q, Zhang W, Li N, Dai Y, Tu J, et al. Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia. Sci Rep. 2017;7:42660 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 s3b
Ku S, Rosario S, Wang Y, Mu P, Seshadri M, Goodrich Z, et al. Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance. Science. 2017;355:78-83 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Sabanov V, Braat S, D Andrea L, Willemsen R, Zeidler S, Rooms L, et al. Impaired GABAergic inhibition in the hippocampus of Fmr1 knockout mice. Neuropharmacology. 2017;116:71-81 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3d
Bodrikov V, Pauschert A, Kochlamazashvili G, Stuermer C. Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons. Exp Neurol. 2017;289:31-45 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 8b
Perland E, Hellsten S, Lekholm E, Eriksson M, Arapi V, Fredriksson R. The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. J Mol Neurosci. 2017;61:199-214 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 3b
  • 免疫印迹; 小鼠; 1:8000; 图 3c
Fröhlich D, Suchowerska A, Spencer Z, von Jonquieres G, Klugmann C, Bongers A, et al. In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Neurobiol Dis. 2017;97:24-35 pubmed 出版商
  • 免疫印迹; 小鼠; 1:15,000; 图 4f
Laclair K, Donde A, Ling J, Jeong Y, Chhabra R, Martin L, et al. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016;132:859-873 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:25; 图 1b
Spendiff S, Vuda M, Gouspillou G, Aare S, Pérez A, Morais J, et al. Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol. 2016;594:7361-7379 pubmed 出版商
  • 免疫印迹; 大鼠; 1:100; 图 s1
Torres Vega E, Duran Moreno M, Sánchez del Pino M, Yañez Y, Canete A, Castel V, et al. Immunoproteomic studies on paediatric opsoclonus-myoclonus associated with neuroblastoma. J Neuroimmunol. 2016;297:98-102 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Li T, Braunstein K, Zhang J, Lau A, Sibener L, Deeble C, et al. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nat Commun. 2016;7:12082 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 3
Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:1000; 图 7g
  • 免疫印迹; 大鼠; 1:1000; 图 6e
Zhao T, Li C, Wei W, Zhang H, Ma D, Song X, et al. Prenatal ketamine exposure causes abnormal development of prefrontal cortex in rat. Sci Rep. 2016;6:26865 pubmed 出版商
  • 免疫组化; 大鼠; 1:25; 图 5
Ren M, Du C, Herrero Acero E, Tang Schomer M, Ozkucur N. A biofidelic 3D culture model to study the development of brain cellular systems. Sci Rep. 2016;6:24953 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2
  • 免疫印迹; 小鼠; 1:1000; 图 2
Liu L, Zhu J, Zhou L, Wan L. RACK1 promotes maintenance of morphine-associated memory via activation of an ERK-CREB dependent pathway in hippocampus. Sci Rep. 2016;6:20183 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 6
Grant E, Hoerder Suabedissen A, Molnár Z. The Regulation of Corticofugal Fiber Targeting by Retinal Inputs. Cereb Cortex. 2016;26:1336-1348 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6B
Benítez B, Cairns N, Schmidt R, Morris J, Norton J, Cruchaga C, et al. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss. Acta Neuropathol Commun. 2015;3:73 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 8
Kim E, Woo M, Qin L, Ma T, Beltran C, Bao Y, et al. Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke. J Neurosci. 2015;35:15113-26 pubmed 出版商
  • 免疫组化; 人类; 1:50
  • 免疫印迹; 人类; 1:5000
Henstridge C, Jackson R, Kim J, Herrmann A, Wright A, Harris S, et al. Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun. 2015;3:53 pubmed 出版商
  • 免疫沉淀; pigs ; 图 3
  • 免疫印迹; pigs ; 图 1d,3
  • 免疫沉淀; 人类; 图 3
  • 免疫印迹; 人类; 图 1c
Betzer C, Movius A, Shi M, Gai W, Zhang J, Jensen P. Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein. PLoS ONE. 2015;10:e0116473 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:1000; 图 1a
Wang X, Wu Y, Yang X, Miao Y, Zhang C, Dong L, et al. Cannabinoid CB1 receptor signaling dichotomously modulates inhibitory and excitatory synaptic transmission in rat inner retina. Brain Struct Funct. 2016;221:301-16 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Jebelli J, Hooper C, Pocock J. Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration. Neurosci Lett. 2014;583:92-7 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Huang Y, Dai L, Gaines D, Droz Rosario R, Lu H, Liu J, et al. BCCIP suppresses tumor initiation but is required for tumor progression. Cancer Res. 2013;73:7122-33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 1
Tan M, Yu J, Jiang T, Zhu X, Guan H, Tan L. IL12/23 p40 inhibition ameliorates Alzheimer's disease-associated neuropathology and spatial memory in SAMP8 mice. J Alzheimers Dis. 2014;38:633-46 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:10
Busse B, Smith S. Automated analysis of a diverse synapse population. PLoS Comput Biol. 2013;9:e1002976 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200
  • 免疫印迹; 大鼠
Zhang H, Zhang X, Wang W, Xue Q, Lu H, Huang J, et al. Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats. PLoS ONE. 2012;7:e46666 pubmed 出版商
Garcia Mesa Y, Xu H, Vance P, Gruenewald A, Garza R, Midkiff C, et al. Dimethyl Fumarate, an Approved Multiple Sclerosis Treatment, Reduces Brain Oxidative Stress in SIV-Infected Rhesus Macaques: Potential Therapeutic Repurposing for HIV Neuroprotection. Antioxidants (Basel). 2021;10: pubmed 出版商
Hughes G, Lones M, Bedder M, Currie P, Smith S, Pownall M. Machine learning discriminates a movement disorder in a zebrafish model of Parkinson's disease. Dis Model Mech. 2020;13: pubmed 出版商
Garcia Mesa Y, Garza R, Diaz Ortiz M, Gruenewald A, Bastien B, Lobrovich R, et al. Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression. J Virol. 2020;94: pubmed 出版商
Hesse R, Hurtado M, Jackson R, Eaton S, Herrmann A, Colom Cadena M, et al. Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype. Acta Neuropathol Commun. 2019;7:214 pubmed 出版商
White M, Lin Z, Kim E, Henstridge C, Pena Altamira E, Hunt C, et al. Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss. Acta Neuropathol Commun. 2019;7:166 pubmed 出版商
Petrie J, Swan C, Ingram R, Frame F, Collins A, Dumay Odelot H, et al. Effects on prostate cancer cells of targeting RNA polymerase III. Nucleic Acids Res. 2019;47:3937-3956 pubmed 出版商
Zhou X, Zhang R, Zhang S, Wu J, Sun X. Activation of 5-HT1A Receptors Promotes Retinal Ganglion Cell Function by Inhibiting the cAMP-PKA Pathway to Modulate Presynaptic GABA Release in Chronic Glaucoma. J Neurosci. 2019;39:1484-1504 pubmed 出版商
Kapchinsky S, Vuda M, Miguez K, Elkrief D, de Souza A, Baglole C, et al. Smoke-induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in chronic obstructive pulmonary disease. J Physiol. 2018;596:2865-2881 pubmed 出版商
White M, Kim E, Duffy A, Adalbert R, Phillips B, Peters O, et al. TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD. Nat Neurosci. 2018;21:552-563 pubmed 出版商
Wu X, Lu H, Hu L, Gong W, Wang J, Fu C, et al. Chronic intermittent hypoxia affects endogenous serotonergic inputs and expression of synaptic proteins in rat hypoglossal nucleus. Am J Transl Res. 2017;9:546-557 pubmed
Wang G, Smith S, Mourrain P. Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses. elife. 2016;5: pubmed 出版商
Jackson R, Rudinskiy N, Herrmann A, Croft S, Kim J, Petrova V, et al. Human tau increases amyloid ? plaque size but not amyloid ?-mediated synapse loss in a novel mouse model of Alzheimer's disease. Eur J Neurosci. 2016;44:3056-3066 pubmed 出版商
Xiao Y, Chen X, Zhang P, Xu Q, Zheng H, Xu G. TRPV1-mediated presynaptic transmission in basolateral amygdala contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation. Sci Rep. 2016;6:29026 pubmed 出版商
Henstridge C, Jackson R, Kim J, Herrmann A, Wright A, Harris S, et al. Erratum to: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun. 2015;3:83 pubmed 出版商
Chrysostomou A, Grady J, Laude A, Taylor R, Turnbull D, Lax N. Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease. Neuropathol Appl Neurobiol. 2016;42:477-92 pubmed 出版商
D Souza Y, Elharram A, Soon Shiong R, Andrew R, Bennett B. Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease. Mol Brain. 2015;8:27 pubmed 出版商
Özkucur N, Quinn K, Pang J, DU C, Georgakoudi I, Miller E, et al. Membrane potential depolarization causes alterations in neuron arrangement and connectivity in cocultures. Brain Behav. 2015;5:24-38 pubmed 出版商
Fortin D, Tillo S, Yang G, Rah J, Melander J, Bai S, et al. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. J Neurosci. 2014;34:16698-712 pubmed 出版商
Van Steenwinckel J, Auvynet C, Sapienza A, Reaux Le Goazigo A, Combadière C, Melik Parsadaniantz S. Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve. Brain Behav Immun. 2015;45:198-210 pubmed 出版商
Tai H, Wang B, Serrano Pozo A, Frosch M, Spires Jones T, Hyman B. Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease. Acta Neuropathol Commun. 2014;2:146 pubmed 出版商
Tian X, Guo X, Ruan Z, Lei Y, Chen Y, Zhang H. Long-term vision and non-vision dominant behavioral deficits in the 2-VO rats are accompanied by time and regional glial activation in the white matter. PLoS ONE. 2014;9:e101120 pubmed 出版商
Masser D, VanGuilder Starkey H, Bixler G, Dunton W, Bronson S, Freeman W. Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats. Exp Eye Res. 2014;125:95-106 pubmed 出版商
Ting J, Marks D, Schleidt S, Wu J, Zyskind J, Lindl K, et al. Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits. J Neurochem. 2014;129:850-63 pubmed 出版商
Ali Rahmani F, Grigson P, Lee S, Neely E, Connor J, Schengrund C. H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment. Neurobiol Aging. 2014;35:1511.e1-12 pubmed 出版商
Tu D, Chung Y, Gil E, Seth A, Franck D, Cristofaro V, et al. Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty. Biomaterials. 2013;34:8681-9 pubmed 出版商
Polydoro M, de Calignon A, Suarez Calvet M, Sanchez L, Kay K, Nicholls S, et al. Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease. J Neurosci. 2013;33:13300-11 pubmed 出版商
Li Y, Zhang H, Zhu X, Feng D, Gong J, Han T. Interleukin-24 induces neuroblastoma SH-SY5Y cell differentiation, growth inhibition, and apoptosis by promoting ROS production. J Interferon Cytokine Res. 2013;33:709-14 pubmed 出版商
Xu Z, Wang L, Chen G, Rao X, Xu F. Roles of GSK3? in odor habituation and spontaneous neural activity of the mouse olfactory bulb. PLoS ONE. 2013;8:e63598 pubmed 出版商
Xu Z, Gao Y, Xu F. Deficits of peripheral olfactory inputs reduce cell proliferation in the adult subventricular and subgranular zones. Neurosci Lett. 2013;541:269-74 pubmed 出版商
Tai H, Serrano Pozo A, Hashimoto T, Frosch M, Spires Jones T, Hyman B. The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. Am J Pathol. 2012;181:1426-35 pubmed 出版商
Pekala D, Blasiak T, Raastad M, Lewandowski M. The influence of orexins on the firing rate and pattern of rat intergeniculate leaflet neurons--electrophysiological and immunohistological studies. Eur J Neurosci. 2011;34:1406-18 pubmed 出版商
Devi L, Ohno M. Mitochondrial dysfunction and accumulation of the ?-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice. Neurobiol Dis. 2012;45:417-24 pubmed 出版商
Bakhshalizadeh S, Esmaeili F, Houshmand F, Shirzad H, Saedi M. Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells. In Vitro Cell Dev Biol Anim. 2011;47:550-7 pubmed 出版商
Lasagna Reeves C, Castillo Carranza D, Sengupta U, Clos A, Jackson G, Kayed R. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener. 2011;6:39 pubmed 出版商
Micheva K, Busse B, Weiler N, O Rourke N, Smith S. Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers. Neuron. 2010;68:639-53 pubmed 出版商
Gil Bea F, Aisa B, Solomon A, Solas M, del Carmen Mugueta M, Winblad B, et al. HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease. J Alzheimers Dis. 2010;22:829-38 pubmed 出版商
van Velthoven C, Kavelaars A, van Bel F, Heijnen C. Repeated mesenchymal stem cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and maturation of new neurons and oligodendrocytes leading to restoration of damage, corticospinal motor tract activity, and sensorimotor funct. J Neurosci. 2010;30:9603-11 pubmed 出版商
Bate C, Tayebi M, Williams A. Phospholipase A2 inhibitors protect against prion and Abeta mediated synapse degeneration. Mol Neurodegener. 2010;5:13 pubmed 出版商
Kraemer B, Schuck T, Wheeler J, Robinson L, Trojanowski J, Lee V, et al. Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis. Acta Neuropathol. 2010;119:409-19 pubmed 出版商
Solbu T, Bjørkmo M, Berghuis P, Harkany T, Chaudhry F. SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic Neurons. Front Neuroanat. 2010;4:1 pubmed 出版商
Zeng F, Watson R, Nash M. Glial cell-derived neurotrophic factor enhances synaptic communication and 5-hydroxytryptamine 3a receptor expression in enteric neurons. Gastroenterology. 2010;138:1491-501 pubmed 出版商
SCAVONE J, Mackie K, Van Bockstaele E. Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors. Brain Res. 2010;1312:18-31 pubmed 出版商
von Maltzahn J, Kreuzberg M, Matern G, Euwens C, Höher T, Wörsdörfer P, et al. C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice. Eur J Cell Biol. 2009;88:481-94 pubmed 出版商
Migani P, Bartlett C, Dunlop S, Beazley L, Rodger J. Regional and cellular distribution of ephrin-B1 in adult mouse brain. Brain Res. 2009;1247:50-61 pubmed 出版商
Meyer Luehmann M, Spires Jones T, Prada C, Garcia Alloza M, de Calignon A, Rozkalne A, et al. Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. Nature. 2008;451:720-4 pubmed 出版商
Khurana R, Devaud L. Sex differences in neurotransmission parameters in response to repeated mild restraint stress exposures in intact male, female and ovariectomised female rats. J Neuroendocrinol. 2007;19:511-20 pubmed
Pina Oviedo S, de Leon Bojorge B, Cuesta Mejías T, White M, Ortiz Hidalgo C, Khalili K, et al. Glioblastoma multiforme with small cell neuronal-like component: association with human neurotropic JC virus. Acta Neuropathol. 2006;111:388-96 pubmed
Birkenkamp Demtroder K, Wagner L, Brandt Sørensen F, Bording Astrup L, Gartner W, Scherubl H, et al. Secretagogin is a novel marker for neuroendocrine differentiation. Neuroendocrinology. 2005;82:121-38 pubmed
产品信息
目录号 :
ab8049
ItemName :
抗突触素抗体[SY38]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
SY38
规格 :
1毫克
物种摘要 :
Cow, Hm, Hu, Ms, Rat
用途 :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, WB
规格说明 :
Other sizes available: 1 ml,500 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。