产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-Tau antibody [TAU-5] - BSA and Azide free
目录 :
ab80579
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
Tau-5
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, proximity ligation assay, 免疫印迹基因敲除验证
文章摘录数: 38
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 2a
  • 免疫印迹; 人类; 1:2000; 图 1a
Mroczek K, Fernando S, Fisher P, Annesley S. Interactions and Cytotoxicity of Human Neurodegeneration- Associated Proteins Tau and α-Synuclein in the Simple Model Dictyostelium discoideum. Front Cell Dev Biol. 2021;9:741662 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 8a
Villanueva E, Tresse E, Liu Y, Duarte J, Jimenez Duran G, Ejlerskov P, et al. Neuronal TNFα, Not α-Syn, Underlies PDD-Like Disease Progression in IFNβ-KO Mice. Ann Neurol. 2021;90:789-807 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 2a
Zheng J, Tian N, Liu F, Zhang Y, Su J, Gao Y, et al. A novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies. Signal Transduct Target Ther. 2021;6:269 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Wu D, Gao D, Yu H, Pi G, Xiong R, Lei H, et al. Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway. Clin Transl Med. 2021;11:e428 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Dong Y, Liang F, Huang L, Fang F, Yang G, Tanzi R, et al. The anesthetic sevoflurane induces tau trafficking from neurons to microglia. Commun Biol. 2021;4:560 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Shin M, Vázquez Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón Pérez C, et al. Reducing acetylated tau is neuroprotective in brain injury. Cell. 2021;184:2715-2732.e23 pubmed 出版商
  • proximity ligation assay; 人类; 1:2000; 图 1d
  • proximity ligation assay; 小鼠; 1:250; 图 s3
Bengoa Vergniory N, Velentza Almpani E, Silva A, Scott C, Vargas Caballero M, Sastre M, et al. Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer's disease. Acta Neuropathol Commun. 2021;9:18 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a, 1b
Hu S, Hu M, Liu J, Zhang B, Zhang Z, Zhou F, et al. Phosphorylation of Tau and α-Synuclein Induced Neurodegeneration in MPTP Mouse Model of Parkinson's Disease. Neuropsychiatr Dis Treat. 2020;16:651-663 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5e
Shi H, Wang Q, Zheng M, Hao S, Lum J, Chen X, et al. Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice. J Neuroinflammation. 2020;17:77 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1b, 2a
Ye J, Yin Y, Liu H, Fang L, Tao X, Wei L, et al. Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation. Aging Cell. 2020;19:e13055 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 图 5a
Ercan Herbst E, Ehrig J, Schöndorf D, Behrendt A, Klaus B, Gomez Ramos B, et al. A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer's disease brain. Acta Neuropathol Commun. 2019;7:192 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1f
Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed 出版商
  • 免疫沉淀; 人类; 图 4b
Silva M, Ferguson F, Cai Q, Donovan K, Nandi G, Patnaik D, et al. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. elife. 2019;8: pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:1000; 表 1
  • 免疫细胞化学; 人类; 1:50; 表 2
  • 免疫印迹; 小鼠
Ercan E, Eid S, Weber C, Kowalski A, Bichmann M, Behrendt A, et al. A validated antibody panel for the characterization of tau post-translational modifications. Mol Neurodegener. 2017;12:87 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:250; 图 2a
Yadirgi G, Stickings P, Rajagopal S, Liu Y, Sesardic D. Immuno-detection of cleaved SNAP-25 from differentiated mouse embryonic stem cells provides a sensitive assay for determination of botulinum A toxin and antitoxin potency. J Immunol Methods. 2017;451:90-99 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 1f
Loss O, Stephenson F. Developmental changes in trak-mediated mitochondrial transport in neurons. Mol Cell Neurosci. 2017;80:134-147 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 4d
  • 免疫印迹; 大鼠; 1:500; 图 4e
Sadick J, Boutin M, Hoffman Kim D, Darling E. Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations. Sci Rep. 2016;6:33999 pubmed 出版商
  • 免疫组化; 人类; 图 3
Ayyadevara S, Balasubramaniam M, Parcon P, Barger S, Griffin W, Alla R, et al. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell. 2016;15:924-39 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
Cheng Y, Huang C, Lee Y, Tien L, Ku W, Chien R, et al. Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep. 2016;6:30314 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 8
CARTAGENA C, Mountney A, Hwang H, Swiercz A, Rammelkamp Z, Boutte A, et al. Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury. PLoS ONE. 2016;11:e0158576 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2c
Connell J, Allison R, Reid E. Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin. PLoS ONE. 2016;11:e0152413 pubmed 出版商
  • 免疫印迹; 人类; 1:800; 图 3
  • 免疫印迹; 小鼠; 1:800; 图 3
Jiang T, Zhang Y, Chen Q, Gao Q, Zhu X, Zhou J, et al. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice. Neuropharmacology. 2016;105:196-206 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 7
Chauhan S, Ahmed Z, Bradfute S, Arko Mensah J, Mandell M, Won Choi S, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun. 2015;6:8620 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 图 2a,b
Richens J, Vere K, Light R, Soria D, Garibaldi J, Smith A, et al. Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluid. Int J Mol Epidemiol Genet. 2014;5:53-70 pubmed
  • 免疫印迹; 小鼠; 1:800; 图 1
Tan M, Yu J, Jiang T, Zhu X, Guan H, Tan L. IL12/23 p40 inhibition ameliorates Alzheimer's disease-associated neuropathology and spatial memory in SAMP8 mice. J Alzheimers Dis. 2014;38:633-46 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Zhang X, Hernandez I, Rei D, Mair W, Laha J, Cornwell M, et al. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. J Biol Chem. 2013;288:22042-56 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类; 图 2a
Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen K, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry. 2013;18:1225-34 pubmed 出版商
Zhao Y, Zeng C, Li X, Yang T, Kuang X, Du J. Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease. Aging Cell. 2020;:e13239 pubmed 出版商
Gasperini L, Rossi A, Cornella N, Peroni D, Zuccotti P, Potrich V, et al. The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization. Mol Biol Cell. 2018;:mbcE18020108 pubmed 出版商
Zhu Y, Zhan G, Fenik P, Brandes M, Bell P, Francois N, et al. Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice. J Neurosci. 2018;38:10255-10270 pubmed 出版商
Wang Y, Hall R, Lee M, Kamgar Parsi A, Bi X, Baudry M. The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation. Sci Rep. 2017;7:11771 pubmed 出版商
Lombardi L, Zaghlula M, Sztainberg Y, BAKER S, Klisch T, Tang A, et al. An RNA interference screen identifies druggable regulators of MeCP2 stability. Sci Transl Med. 2017;9: pubmed 出版商
Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed 出版商
Xu W, Liu J, Ma D, Yuan G, Lu Y, Yang Y. Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats. PLoS ONE. 2017;12:e0172477 pubmed 出版商
He X, Li Z, Rizak J, Wu S, Wang Z, He R, et al. Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells. Front Neurosci. 2016;10:598 pubmed 出版商
Mansuroglu Z, Benhelli Mokrani H, Marcato V, Sultan A, Violet M, Chauderlier A, et al. Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin. Sci Rep. 2016;6:33047 pubmed 出版商
Min S, Chen X, Tracy T, Li Y, Zhou Y, Wang C, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015;21:1154-62 pubmed 出版商
Oz S, Ivashko Pachima Y, Gozes I. The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities. PLoS ONE. 2012;7:e51458 pubmed 出版商
产品信息
目录号 :
ab80579
ItemName :
Anti-Tau antibody [TAU-5] - BSA and Azide free
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
TAU-5
规格 :
100微升
物种摘要 :
Cow, Hu, Ms, Rat, Shp
纯度 :
免疫原亲和纯化
应用摘要 :
ELISA, Flow Cyt, ICC/IF, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。