产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗AKT1(磷酸化S473)抗体[EP2109Y]
目录 :
ab81283
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP2109Y
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, dot blot
文章摘录数: 53
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:3000
Xu J, Liu Y, Liu J, Shou Y, Xiong Z, Xiong H, et al. Low Expression Levels of SLC22A12 Indicates a Poor Prognosis and Progresses Clear Cell Renal Cell Carcinoma. Front Oncol. 2021;11:659208 pubmed 出版商
  • 免疫组化; 大鼠; 图 6b
  • 免疫印迹; 大鼠; 1:1000; 图 6a
Li Z, Meng Y, Liu C, Liu H, Cao W, Tong C, et al. Kcnh2 mediates FAK/AKT-FOXO3A pathway to attenuate sepsis-induced cardiac dysfunction. Cell Prolif. 2021;54:e12962 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4a
Cui P, Jing P, Liu X, Xu W. Prognostic Significance of PD-L1 Expression and Its Tumor-Intrinsic Functions in Hypopharyngeal Squamous Cell Carcinoma. Cancer Manag Res. 2020;12:5893-5902 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Chu N, Viennet T, Bae H, Salguero A, Boeszoermenyi A, Arthanari H, et al. The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 6j
Qian W, Cai X, Qian Q. Sirt1 antisense long non-coding RNA attenuates pulmonary fibrosis through sirt1-mediated epithelial-mesenchymal transition. Aging (Albany NY). 2020;12:4322-4336 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5b
Chen Z, Zhang J, Xue H, Qian M, Guo X, Gao X, et al. Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition. Integr Cancer Ther. 2020;19:1534735419900927 pubmed 出版商
  • 免疫印迹; 人类; 图 7a, 7b
Franklin W, Krishnan B, Taglialatela G. Chronic synaptic insulin resistance after traumatic brain injury abolishes insulin protection from amyloid beta and tau oligomer-induced synaptic dysfunction. Sci Rep. 2019;9:8228 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Wang J, Wang F, Zhu J, Song M, An J, Li W. Transcriptome Profiling Reveals PHLDA1 as a Novel Molecular Marker for Ischemic Cardiomyopathy. J Mol Neurosci. 2018;65:102-109 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 s1c
Hyrenius Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh M, Song G, et al. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. Nat Commun. 2018;9:1770 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5a
Yang R, Tao Z, Huang M, Zheng Y, Dai M, Zou Y, et al. Knockout of the placenta specific 8 gene radiosensitizes nasopharyngeal carcinoma cells by activating the PI3K/AKT/GSK3β pathway. Am J Transl Res. 2018;10:455-464 pubmed
  • 免疫组化; 小鼠; 图 5b
zur Nedden S, Eith R, Schwarzer C, Zanetti L, Seitter H, Fresser F, et al. Protein kinase N1 critically regulates cerebellar development and long-term function. J Clin Invest. 2018;128:2076-2088 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000; 图 2a
El Gamal H, Eid A, Munusamy S. Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury. Biomed Res Int. 2017;2017:5903105 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Chen J, Wang Z, Yu S. AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway. Onco Targets Ther. 2017;10:811-817 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Jafari N, Kim H, Park R, Li L, Jang M, Morris A, et al. CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells. PLoS ONE. 2017;12:e0170327 pubmed 出版商
  • 免疫印迹; 小鼠; 图 S1b
Liu Z, Gan L, Wu T, Feng F, Luo D, Gu H, et al. Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis. 2016;7:e2487 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Kong X, Liu F, Gao J. MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways. Oncotarget. 2016;7:66051-66060 pubmed 出版商
  • 流式细胞仪; 人类; 图 1e
Hedl M, Yan J, Abraham C. IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation. Cell Rep. 2016;16:2442-55 pubmed 出版商
  • 免疫组化; 人类; 图 6
  • 免疫印迹; 人类; 图 4
Khanom R, Nguyen C, Kayamori K, Zhao X, Morita K, Miki Y, et al. Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth. PLoS ONE. 2016;11:e0161163 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Liang Q, Wang B, Pang L, Wang Y, Zheng M, Wang Q, et al. Application of citrate as a tricarboxylic acid (TCA) cycle intermediate, prevents diabetic-induced heart damages in mice. Iran J Basic Med Sci. 2016;19:43-8 pubmed
  • 免疫组化; 小鼠; 1:100; 图 6a
Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed 出版商
  • 免疫组化; 小鼠; 图 st1
Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, et al. Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. Liver Int. 2016;36:1176-86 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3
Jung Y, Wang J, Lee E, McGee S, Berry J, Yumoto K, et al. Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow. Mol Cancer Res. 2015;13:197-207 pubmed 出版商
Chen Y, Chen N, Xu J, Wang X, Wei X, Tang C, et al. Apatinib inhibits the proliferation of gastric cancer cells via the AKT/GSK signaling pathway in vivo. Aging (Albany NY). 2021;13:20738-20747 pubmed 出版商
Wu M, Xia X, Hu J, Fowlkes N, Li S. WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression. Nat Commun. 2021;12:3500 pubmed 出版商
Meng W, Meng J, Jiang H, Feng X, Wei D, Ding Q. FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway. Anal Cell Pathol (Amst). 2020;2020:6021602 pubmed 出版商
Cheng G, Liu Y, Liu L, Ruan H, Cao Q, Song Z, et al. LINC00160 mediates sunitinib resistance in renal cell carcinoma via SAA1 that is implicated in STAT3 activation and compound transportation. Aging (Albany NY). 2020;12:17459-17479 pubmed 出版商
Hou Y, Hu Z, Gong X, Yang B. HSPB8 overexpression prevents disruption of blood-brain barrier after intracerebral hemorrhage in rats through Akt/GSK3β/β-catenin signaling pathway. Aging (Albany NY). 2020;12:17568-17581 pubmed 出版商
Zhou J, Yang Z, Cheng S, Yu J, Huang C, Feng Q. miRNA-425-5p enhances lung cancer growth via the PTEN/PI3K/AKT signaling axis. BMC Pulm Med. 2020;20:223 pubmed 出版商
Sedlic F, Seiwerth F, Sepac A, Sikiric S, Cindric M, Milavic M, et al. Mitochondrial ROS Induce Partial Dedifferentiation of Human Mesothelioma via Upregulation of NANOG. Antioxidants (Basel). 2020;9: pubmed 出版商
Wei F, Wang A, Wang Q, Han W, Rong R, Wang L, et al. Plasma endothelial cells-derived extracellular vesicles promote wound healing in diabetes through YAP and the PI3K/Akt/mTOR pathway. Aging (Albany NY). 2020;12:12002-12018 pubmed 出版商
Jiang T, Chen Z, Chen Z, Tan D. SULF2 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells through the ERK/AKT signaling pathway. Braz J Med Biol Res. 2020;53:e8901 pubmed 出版商
Shan J, Al Muftah M, Al Kowari M, Abuaqel S, Al Rumaihi K, Al Bozom I, et al. Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer. Cell Death Discov. 2019;5:139 pubmed 出版商
Dong S, Zhang X, Liu D. Overexpression of long noncoding RNA GAS5 suppresses tumorigenesis and development of gastric cancer by sponging miR-106a-5p through the Akt/mTOR pathway. Biol Open. 2019;: pubmed 出版商
Wang Y, Tao J, Wang M, Yang L, Ning F, Xin H, et al. Mechanism of Regulation of Big-Conductance Ca2+-Activated K+ Channels by mTOR Complex 2 in Podocytes. Front Physiol. 2019;10:167 pubmed 出版商
He J, Deng L, Liu H, Chen T, Chen S, Xia S, et al. BCL2L10/BECN1 modulates hepatoma cells autophagy by regulating PI3K/AKT signaling pathway. Aging (Albany NY). 2019;11:350-370 pubmed 出版商
Zhu T, An S, Choy M, Zhou J, Wu S, Liu S, et al. LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression. J Cell Mol Med. 2018;: pubmed 出版商
Huang M, Huang B, Li G, Zeng S. Apatinib affect VEGF-mediated cell proliferation, migration, invasion via blocking VEGFR2/RAF/MEK/ERK and PI3K/AKT pathways in cholangiocarcinoma cell. BMC Gastroenterol. 2018;18:169 pubmed 出版商
Zhang Y, Cao C, Xin J, Lv P, Chen D, Li S, et al. Treatment with placental growth factor attenuates myocardial ischemia/reperfusion injury. PLoS ONE. 2018;13:e0202772 pubmed 出版商
Zhao W, Sun M, Li S, Chen Z, Geng D. Transcription factor ATF3 mediates the radioresistance of breast cancer. J Cell Mol Med. 2018;22:4664-4675 pubmed 出版商
Oldrini B, Curiel García A, Marques C, Matia V, Uluçkan O, Graña Castro O, et al. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun. 2018;9:1466 pubmed 出版商
Ding Q, Sun P, Zhou H, Wan B, Yin J, Huang Y, et al. Lack of endogenous parathyroid hormone delays fracture healing by inhibiting vascular endothelial growth factor‑mediated angiogenesis. Int J Mol Med. 2018;42:171-181 pubmed 出版商
Chen Y, Lu J, Xia L, Xue D, Yu X, Shen D, et al. Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT3 regulation in seminoma. Cancer Sci. 2018;109:384-394 pubmed 出版商
Tankiewicz Kwedlo A, Hermanowicz J, Domaniewski T, Pawlak K, Rusak M, Pryczynicz A, et al. Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer. Br J Pharmacol. 2017;: pubmed 出版商
Zhang K, Wu S, Li Z, Zhou J. MicroRNA-211/BDNF axis regulates LPS-induced proliferation of normal human astrocyte through PI3K/AKT pathway. Biosci Rep. 2017;37: pubmed 出版商
Kamerkar S, LeBleu V, Sugimoto H, Yang S, Ruivo C, Melo S, et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017;546:498-503 pubmed 出版商
Marcusso Orsini T, Kawakami N, Panis C, Fortes Dos Santos Thomazelli A, Tomiotto Pellissier F, Cataneo A, et al. Antileishmanial Activity and Inducible Nitric Oxide Synthase Activation by RuNO Complex. Mediators Inflamm. 2016;2016:2631625 pubmed
Lu Y, Wang Y, Zhang M, Liu L, Li F, Zhang J, et al. HER2-siRNA delivered by EGFR-specific single chain antibody inhibits NSCLC cell proliferation and tumor growth. Oncotarget. 2016;7:23594-607 pubmed 出版商
Liang D, Han D, Fan W, Zhang R, Qiao H, Fan M, et al. Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy. Sci Rep. 2016;6:21914 pubmed 出版商
Sajan M, Hansen B, Ivey R, Sajan J, Ari C, Song S, et al. Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development. Diabetes. 2016;65:1892-903 pubmed 出版商
Lv P, Tong X, Peng Q, Liu Y, Jin H, Liu R, et al. Treatment with the herbal medicine, naoxintong improves the protective effect of high-density lipoproteins on endothelial function in patients with type 2 diabetes. Mol Med Rep. 2016;13:2007-16 pubmed 出版商
Wu B, Wang Y, Yang X, Xu B, Feng F, Wang B, et al. Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma. J Exp Clin Cancer Res. 2015;34:110 pubmed 出版商
Wang J, Feng J, Han J, Zhang B, Mao W. The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. Biomed Res Int. 2014;2014:582730 pubmed 出版商
Zhu H, Li C, Bai W, Su L, Liu J, Li Y, et al. MicroRNA-21 regulates hTERT via PTEN in hypertrophic scar fibroblasts. PLoS ONE. 2014;9:e97114 pubmed 出版商
产品信息
目录号 :
ab81283
ItemName :
抗AKT1(磷酸化S473)抗体[EP2109Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP2109Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
Dot, ICC/IF, IHC-Fr, IHC-P, In-Cell ELISA, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。