产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗TSG101抗体[4A10]
目录 :
ab83
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4A10
反应物种 :
人类, 小鼠, 大鼠, fruit fly
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 60
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1b
Cai M, Chai S, Xiong T, Wei J, Mao W, Zhu Y, et al. Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease. Front Cell Dev Biol. 2021;9:695007 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Claude Taupin A, Jia J, Bhujabal Z, Garfa Traoré M, Kumar S, da Silva G, et al. ATG9A protects the plasma membrane from programmed and incidental permeabilization. Nat Cell Biol. 2021;23:846-858 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 6b
Tabariès S, Annis M, Lazaris A, Petrillo S, Huxham J, Abdellatif A, et al. Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern. Commun Biol. 2021;4:657 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 1d
Ganig N, Baenke F, Thepkaysone M, Lin K, Rao V, Wong F, et al. Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Galardi A, Colletti M, Lavarello C, Di Paolo V, Mascio P, Russo I, et al. Proteomic Profiling of Retinoblastoma-Derived Exosomes Reveals Potential Biomarkers of Vitreous Seeding. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s4c
Medeiros B, Goodale D, Postenka C, Lowes L, Kiser P, Hearn S, et al. Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 人类; 图 s5e
Martín Pardillos A, Valls Chiva Á, Bande Vargas G, Hurtado Blanco P, Piñeiro Cid R, Guijarro P, et al. The role of clonal communication and heterogeneity in breast cancer. BMC Cancer. 2019;19:666 pubmed 出版商
  • 免疫印迹; 人类; 1:150; 图 2c
Tiedemann K, Sadvakassova G, Mikolajewicz N, Juhas M, Sabirova Z, Tabariès S, et al. Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis. Transl Oncol. 2019;12:462-474 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 4a
  • 免疫印迹; 小鼠; 1:1000; 图 s7b
Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2b
  • 免疫印迹; 人类; 图 1b
Dean I, Dzinic S, Bernardo M, Zou Y, Kimler V, Li X, et al. The secretion and biological function of tumor suppressor maspin as an exosome cargo protein. Oncotarget. 2017;8:8043-8056 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1
Halin Bergström S, Hägglöf C, Thysell E, Bergh A, Wikstrom P, Lundholm M. Extracellular Vesicles from Metastatic Rat Prostate Tumors Prime the Normal Prostate Tissue to Facilitate Tumor Growth. Sci Rep. 2016;6:31805 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 1
Campoy I, Lanau L, Altadill T, Sequeiros T, Cabrera S, Cubo Abert M, et al. Exosome-like vesicles in uterine aspirates: a comparison of ultracentrifugation-based isolation protocols. J Transl Med. 2016;14:180 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Ruiz Martinez M, Navarro A, Marrades R, Viñolas N, Santasusagna S, Muñoz C, et al. YKT6 expression, exosome release, and survival in non-small cell lung cancer. Oncotarget. 2016;7:51515-51524 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 1
Altadill T, Campoy I, Lanau L, Gill K, Rigau M, Gil Moreno A, et al. Enabling Metabolomics Based Biomarker Discovery Studies Using Molecular Phenotyping of Exosome-Like Vesicles. PLoS ONE. 2016;11:e0151339 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Son S, Cha M, Choi H, Kang S, Choi H, Lee M, et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy. 2016;12:784-800 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1
Baranyai T, Herczeg K, Onódi Z, Voszka I, Módos K, Marton N, et al. Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods. PLoS ONE. 2015;10:e0145686 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Majumder P, Chakrabarti O. Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101. Cell Death Dis. 2015;6:e1970 pubmed 出版商
  • 免疫印迹; 人类; 图 s1b
Maruyama T, Dougan S, Truttmann M, Bilate A, Ingram J, Ploegh H. Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining. Nat Biotechnol. 2015;33:538-42 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Ho D, Yi S, Seo H, Son I, Seol W. Increased DJ-1 in urine exosome of Korean males with Parkinson's disease. Biomed Res Int. 2014;2014:704678 pubmed 出版商
  • 免疫沉淀; fruit fly ; 图 5
Gradilla A, Gonzalez E, Seijo I, Andres G, Bischoff M, González Méndez L, et al. Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion. Nat Commun. 2014;5:5649 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Lundholm M, Schröder M, Nagaeva O, Baranov V, Widmark A, Mincheva Nilsson L, et al. Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion. PLoS ONE. 2014;9:e108925 pubmed 出版商
  • 免疫印迹; 人类; 1:400
Vargas A, Zhou S, Ethier Chiasson M, Flipo D, Lafond J, Gilbert C, et al. Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia. FASEB J. 2014;28:3703-19 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Stalder L, Heusermann W, Sokol L, Trojer D, Wirz J, Hean J, et al. The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. EMBO J. 2013;32:1115-27 pubmed 出版商
  • 免疫印迹; 小鼠
Kim B, Shenoy A, Kumar P, Das R, Tiwari S, MacMicking J. A family of IFN-?-inducible 65-kD GTPases protects against bacterial infection. Science. 2011;332:717-21 pubmed 出版商
Le M, Fernandez Palomo C, McNeill F, Seymour C, Rainbow A, Mothersill C. Exosomes are released by bystander cells exposed to radiation-induced biophoton signals: Reconciling the mechanisms mediating the bystander effect. PLoS ONE. 2017;12:e0173685 pubmed 出版商
Royo F, Zuñiga Garcia P, Sánchez Mosquera P, Egia A, Pérez A, Loizaga A, et al. Different EV enrichment methods suitable for clinical settings yield different subpopulations of urinary extracellular vesicles from human samples. J Extracell Vesicles. 2016;5:29497 pubmed 出版商
Son S, Kang S, Choi H, Mook Jung I. Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway. Mol Neurodegener. 2015;10:56 pubmed 出版商
Ertunc M, Sikkeland J, Fenaroli F, Griffiths G, Daniels M, Cao H, et al. Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. J Lipid Res. 2015;56:423-34 pubmed 出版商
Martz M, Grabocka E, Beeharry N, Yen T, Wedegaertner P. Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission. Mol Biol Cell. 2013;24:2785-94 pubmed 出版商
Dumaresq Doiron K, Jules F, Lefrancois S. Sortilin turnover is mediated by ubiquitination. Biochem Biophys Res Commun. 2013;433:90-5 pubmed 出版商
Alvarez M, Khosroheidari M, Kanchi Ravi R, DISTEFANO J. Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers. Kidney Int. 2012;82:1024-32 pubmed 出版商
Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, et al. Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes. PLoS ONE. 2012;7:e37378 pubmed 出版商
Wang G, Dinkins M, He Q, Zhu G, Poirier C, Campbell A, et al. Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD). J Biol Chem. 2012;287:21384-95 pubmed 出版商
Hu C, Coughlin M, Mitchison T. Midbody assembly and its regulation during cytokinesis. Mol Biol Cell. 2012;23:1024-34 pubmed 出版商
Guescini M, Leo G, Genedani S, Carone C, Pederzoli F, Ciruela F, et al. Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures. Exp Cell Res. 2012;318:603-13 pubmed 出版商
Berndt J, Aoyagi A, Yang P, Anastas J, Tang L, Moon R. Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/?-catenin signaling. J Cell Biol. 2011;194:737-50 pubmed 出版商
Malerød L, Pedersen N, Sem Wegner C, Lobert V, Leithe E, Brech A, et al. Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting. Traffic. 2011;12:1211-26 pubmed 出版商
Yang M, Li Y, Chilukuri K, Brady O, Boulos M, Kappes J, et al. L1 stimulation of human glioma cell motility correlates with FAK activation. J Neurooncol. 2011;105:27-44 pubmed 出版商
Knævelsrud H, Ahlquist T, Merok M, Nesbakken A, Stenmark H, Lothe R, et al. UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy. Autophagy. 2010;6:863-70 pubmed 出版商
Masyuk A, Huang B, Ward C, Gradilone S, Banales J, Masyuk T, et al. Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia. Am J Physiol Gastrointest Liver Physiol. 2010;299:G990-9 pubmed 出版商
Conde Vancells J, Rodriguez Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, et al. Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl. 2010;4:416-25 pubmed 出版商
Tizon B, Ribe E, Mi W, Troy C, Levy E. Cystatin C protects neuronal cells from amyloid-beta-induced toxicity. J Alzheimers Dis. 2010;19:885-94 pubmed 出版商
Fernández Llama P, Khositseth S, Gonzales P, Star R, Pisitkun T, Knepper M. Tamm-Horsfall protein and urinary exosome isolation. Kidney Int. 2010;77:736-42 pubmed 出版商
Yang M, Adla S, Temburni M, Patel V, Lagow E, Brady O, et al. Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule. Cancer Cell Int. 2009;9:27 pubmed 出版商
Pawliczek T, Crump C. Herpes simplex virus type 1 production requires a functional ESCRT-III complex but is independent of TSG101 and ALIX expression. J Virol. 2009;83:11254-64 pubmed 出版商
Guescini M, Genedani S, Stocchi V, Agnati L. Astrocytes and Glioblastoma cells release exosomes carrying mtDNA. J Neural Transm (Vienna). 2010;117:1-4 pubmed 出版商
Michael A, Bajracharya S, Yuen P, Zhou H, Star R, Illei G, et al. Exosomes from human saliva as a source of microRNA biomarkers. Oral Dis. 2010;16:34-8 pubmed 出版商
Molle D, Segura Morales C, Camus G, Berlioz Torrent C, Kjems J, Basyuk E, et al. Endosomal trafficking of HIV-1 gag and genomic RNAs regulates viral egress. J Biol Chem. 2009;284:19727-43 pubmed 出版商
Agromayor M, Carlton J, Phelan J, Matthews D, Carlin L, Ameer Beg S, et al. Essential role of hIST1 in cytokinesis. Mol Biol Cell. 2009;20:1374-87 pubmed 出版商
Aharon A, Tamari T, Brenner B. Monocyte-derived microparticles and exosomes induce procoagulant and apoptotic effects on endothelial cells. Thromb Haemost. 2008;100:878-85 pubmed
Petiot A, Strappazzon F, Chatellard Causse C, Blot B, Torch S, Verna J, et al. Alix differs from ESCRT proteins in the control of autophagy. Biochem Biophys Res Commun. 2008;375:63-8 pubmed 出版商
Philips J, Porto M, Wang H, Rubin E, Perrimon N. ESCRT factors restrict mycobacterial growth. Proc Natl Acad Sci U S A. 2008;105:3070-5 pubmed 出版商
McDonald B, Martin Serrano J. Regulation of Tsg101 expression by the steadiness box: a role of Tsg101-associated ligase. Mol Biol Cell. 2008;19:754-63 pubmed
Niendorf S, Oksche A, Kisser A, Löhler J, Prinz M, Schorle H, et al. Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol Cell Biol. 2007;27:5029-39 pubmed
Agromayor M, Martin Serrano J. Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargo. J Biol Chem. 2006;281:23083-91 pubmed
Zhou H, Yuen P, Pisitkun T, Gonzales P, Yasuda H, Dear J, et al. Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery. Kidney Int. 2006;69:1471-6 pubmed
Bowers K, Piper S, Edeling M, Gray S, Owen D, Lehner P, et al. Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem. 2006;281:5094-105 pubmed
Segura Morales C, Pescia C, Chatellard Causse C, Sadoul R, Bertrand E, Basyuk E. Tsg101 and Alix interact with murine leukemia virus Gag and cooperate with Nedd4 ubiquitin ligases during budding. J Biol Chem. 2005;280:27004-12 pubmed 出版商
Ismaili N, Blind R, Garabedian M. Stabilization of the unliganded glucocorticoid receptor by TSG101. J Biol Chem. 2005;280:11120-6 pubmed
Taylor D, Gercel Taylor C. Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects. Br J Cancer. 2005;92:305-11 pubmed
产品信息
目录号 :
ab83
ItemName :
抗TSG101抗体[4A10]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
4A10
规格 :
100微升
物种摘要 :
Dm, Hu, Ms, Rat
纯度 :
蛋白质G纯化
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。