产品简要
公司名称 :
Abeomics
产品类型 :
抗体
产品名称 :
Monoclonal Antibody to Caspase-3 (Clone: ABM11D3)
目录 :
10-1004
规格 :
100微克
价格 :
260美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
ABM11D3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪
更多信息或购买 :
产品信息
目录代码 :
10-1004
产品名称 :
Monoclonal Antibody to Caspase-3 (Clone: ABM11D3)
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
克隆名称 :
ABM11D3
抗体亚型 :
小鼠IgG1
规格 :
100微克
标价 :
260美元
图像Link4 :
104.238.111.116/Abeomics/abeo_images_2/10-1004/4.jpg
图像Legend4 :
Fig-4: Immunohistochemical analysis of Caspase-3 in human Rectum using anti-Caspase-3 antibody (Clone: ABM11D3) at 5 µg/ml.
图像Link5 :
104.238.111.116/Abeomics/abeo_images_2/10-1004/5.jpg
图像Legend5 :
Fig-5: Western blot analysis of Caspase-3. Anti-Caspase-3 antibody (Clone: ABM11D3) was used at 2 µg/ml on (1) 3T3 and (2) EL-4 lysates.
产品描述 :
Caspases are a member of the cysteine-aspartic acid protease family. Caspase-3 (31 kDa) is an executionary caspase which directly cleaves and activates poly(ADP-ribose) polymerase (PARP), sterol regulatory element binding proteins (SREBPs) or it can also interact with other caspases like caspase-6, -7 and -9. Increased levels of caspase-3 are involved in Huntington Disease-associated cell death. Caspase-3 is the principal caspase in mediating the cleavage of amyloid-beta 4A precursor protein (APP), which is related with neuronal death in Alzheimer's disease. Like other caspases, caspase-3 is also synthesized as a zymogen procaspase which is activated by specific proteolytic cleavage. High levels of caspase-3 are observed in lung, spleen, heart, liver and kidney, moderate levels in brain and skeletal muscle, and low in testis.
交叉活性 :
小鼠, 人类
物种摘要 :
M, H
别名 :
Apopain, Cysteine protease CPP32, SREBP cleavage activity, SCA-1
免疫原 :
Full length recombinant protein of Caspase-3 was used as the immunogen for this antibody.
纯度 :
蛋白质G色谱
缓冲液 :
PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
防腐剂 :
叠氮化钠
浓度 :
0.5毫克/毫升
用途 :
Western Blot Analysis 0.5-4 µg/ml, FACS: 0.5-1 µg/10^6, IHC: 5-10 µg/ml. Pack of 25 µg is also availabe .
应用摘要 :
免疫组化, 流式细胞仪, 免疫印迹
储存 :
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
更多信息或购买 :
公司信息
Abeomics
9853 Pacific Heights Blvd., Suite D.
San Diego, CA 92121
support@abeomics.com
www.abeomics.com
858-263-4982
公司总部: 美国