产品简要
公司名称 :
Abeomics
产品类型 :
抗体
产品名称 :
Monoclonal Antibody to TLR5 (Clone: ABM22G1)
目录 :
10-3013
规格 :
100微克
价格 :
260美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
ABM22G1
反应物种 :
人类
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
产品信息
目录代码 :
10-3013
产品名称 :
Monoclonal Antibody to TLR5 (Clone: ABM22G1)
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
克隆名称 :
ABM22G1
抗体亚型 :
小鼠IgG2a
照明链 :
Kappa
规格 :
100微克
标价 :
260美元
产品描述 :
Toll-like receptor 5 (TLR5) plays a fundamental role in pathogen recognition and downstream signaling to induce effective immunity. It is well expressed in major old tissues including lung, skin, intestine, and spleen. TLR5 is present in synovial of patients with rheumatoid arthritis (RA), act as novel mediator of innate immunity-induced osteoclastogenesis and bone loss. TLR5 is a receptor for flagellin and is present on the basolateral surface of intestinal epithelial cells. It is involved in the migration of intestinal epithelial cells through activation of the p38 MAPK pathway. TLR5-mediated signaling specifically enhanced the maturation of lung dendritic cells. TLR5 influences the progression and outcome of ovarian, sarcoma, and luminal breast tumors. Mutations in TLR5 have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
交叉活性 :
人类
物种摘要 :
H
别名 :
Toll样受体5 TIL3
免疫原 :
A partial length recombinant TLR5 protein was used as the immunogen for this antibody.
纯度 :
蛋白质G色谱
缓冲液 :
PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
防腐剂 :
叠氮化钠
浓度 :
0.5毫克/毫升
用途 :
Immunohistochemical analysis: 10 µg/ml;FACS analysis: 0.5 µg/10^6 cells. Pack of 25 µg is also availabe .
应用摘要 :
免疫组化, 流式细胞仪
储存 :
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
更多信息或购买 :
公司信息
Abeomics
9853 Pacific Heights Blvd., Suite D.
San Diego, CA 92121
support@abeomics.com
www.abeomics.com
858-263-4982
公司总部: 美国