抗体

Monoclonal Antibody to Mouse CD196 (Clone: ABM40H1)

10-4100

100微克

110美元

单克隆

大鼠

nonconjugated

ABM40H1

Monoclonal Antibody to Mouse CD196 (Clone: ABM40H1)

抗体

大鼠

单克隆

未共轭

ABM40H1

大鼠IgG2a

Kappa

100微克

110美元

CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or native T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.

小鼠

M

C-趋化因子C受体类型6, C-C CKR-6, KY411

Full length recombinant protein from mCD196 was used as the immunogen for this antibody.

蛋白质G色谱

PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

叠氮化钠

0.5毫克/毫升

Western Blot Analysis 2-4 µg/ml. Pack of 25 µg is also availabe .

免疫印迹

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.