抗体

Monoclonal Antibody to S100A8, human (Clone: ABM4G30)

10-4117

100微克

260美元

单克隆

小鼠

nonconjugated

ABM4G30

Monoclonal Antibody to S100A8, human (Clone: ABM4G30)

抗体

小鼠

单克隆

未共轭

ABM4G30

小鼠IgG2b

Kappa

100微克

260美元

S100A8 is a low molecular weight (10 kDa) secreted cytoplasmic protein belonging to S100 family of calcium- and zinc-binding protein. S100A8 regulates a number of cellular processes, such as, inflammation, antimicrobial, oxidant-scavenging and apoptosis-inducing activities, cell cycle progression and differentiation, leukocyte arachidonic acid trafficking and metabolism. S100A8 is a homodimer but predominantly remains as heterodimer with S100A9 and the S100A8/S100A9 complex is called as Calprotectin. S100A8 is generally expressed in myeloid cells, neutrophils, monocytes and keratinocytes but high levels are found in the serum sample of patients with inflammatory diseases, such as, rheumatoid, cystic fibrosis, inflammatory bowel disease, systemic lupus erythematosus, progressive systemic sclerosis and many other inflammatory diseases. S100A8 is also associated with Psoriasis (an inflammatory skin disorder characterized by keratinocyte hyperproliferation and altered differentiation).

人类

H

S100钙结合蛋白A8 CAGA CFAG MRP8

A full length human S100A8 protein was used as the immunogen for this antibody.

蛋白质G色谱

PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

叠氮化钠

0.5毫克/毫升

Western blot analysis: 2-4 µg/ml. Pack of 25 µg is also availabe .

免疫印迹

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.