抗体

Monoclonal Antibody to FLT1 (Clone: ABM4A56)

10-7564

100微克

260美元

单克隆

小鼠

nonconjugated

ABM4A56

Monoclonal Antibody to FLT1 (Clone: ABM4A56)

抗体

小鼠

单克隆

未共轭

ABM4A56

小鼠IgG2b

Kappa

100微克

260美元

FLT-1 (fms-related tyrosine kinase 1) is an endogenous inhibitor of vascular endothelial growth factor, which is involved in cardiovascular remodeling and atherosclerosis development. It potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). FLT-1 is expressed on tumor cells and is implicated in tumor growth and progression. It is overexpressed in primary tumors and nodal metastasis. FLT-1 regulates monocyte migration, recruits endothelial cell progenitors, increases the adhesive properties of natural killer cells and induces growth factors. It is observed in many diseases with endothelial dysfunction, including pre-eclampsia and diabetic retinopathy, but whether it contributes to endothelial injury in IgAN requires further exploration.

人类

H

FLT1 FLT FRT VEGFR1

A partial length recombinant FLT1 protein (amino acids 102-321) was used as the immunogen for this antibody.

蛋白质G色谱

PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

叠氮化钠

0.5毫克/毫升

Immunohistochemical analysis: 5-10 µg/ml. Pack of 25 µg is also availabe .

免疫组化

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.