抗体

Monoclonal Antibody to CD11c (Clone: ABM4C58)

10-7566

100微克

220美元

单克隆

小鼠

nonconjugated

ABM4C58

免疫组化, 流式细胞仪

Monoclonal Antibody to CD11c (Clone: ABM4C58)

抗体

小鼠

单克隆

未共轭

ABM4C58

小鼠IgG2b

Kappa

100微克

220美元

CD11c/CD18 ( p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages.

人类

H

ITGAX CD11C

A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody.

蛋白质G色谱

PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

叠氮化钠

0.5毫克/毫升

Immunohistochemical analysis: 5-10 µg/ml FACS: 0.5 - 1 µg//10^6 cells. Pack of 25 µg is also availabe .

免疫组化, 流式细胞仪

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.