抗体

多克隆抗体磷酸甘油醛脱氢酶

11-13024

100微克

240美元

多克隆

兔

nonconjugated

人类, 小鼠, 大鼠

多克隆抗体磷酸甘油醛脱氢酶

抗体

兔

多克隆

未共轭

兔IgG

100微克

240美元

GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is an enzyme best known for its role in glycolysis. However, extra-glycolytic functions of GAPDH have been described, including regulation of protein expression via RNA binding. GAPDH binds to numerous AREs (adenine-uridine rich elements) from various mRNA 3'-untranslated regions in vitro and in vivo despite its lack of a canonical RNA binding motif. GAPDH specifically catalyzes the simultaneous phosphorylation and oxidation of glyceraldehyde 3-phosphate using NAD+ (Nicotinamide Adenine Dinucleotide) as a cofactor to produce glycerate 1,3-biphosphate and NADH. In addition to its role in energy production, GAPDH has been implicated in many cellular processes including DNA repair tRNA export, membrane fusion and transport, endocytosis and nuclear membrane assembly, and cell death.

大鼠, 小鼠, 人类

R, M, H

GAPDH, GAPD, CDABP0047, OK/SW-cl.12

A partial length recombinant GAPDH protein was used as the immunogen for this antibody.

蛋白质A色谱

PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

叠氮化钠

0.5毫克/毫升

Western blot analysis: 1-2 µg/ml. Pack of 25 µg is also availabe .

免疫印迹

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.