抗体

多克隆抗体CD11C

11-7547

100微克

240美元

多克隆

兔

nonconjugated

多克隆抗体CD11C

抗体

兔

多克隆

未共轭

兔IgG

100微克

240美元

CD11c/CD18 is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages.

人类

H

ITGAX CD11C

A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody.

蛋白质A色谱

PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

叠氮化钠

0.5毫克/毫升

Western blot analysis: 1-2 µg/ml. Pack of 25 µg is also availabe .

免疫印迹

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.