产品简要
公司名称 :
亚诺法生技股份有限公司
产品类型 :
抗体
产品名称 :
DYRK1A单克隆抗体(M01), 克隆7D10
目录 :
H00001859-M01
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
7D10
反应物种 :
人类, 小鼠, 大鼠, 人类免疫缺陷病毒1
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫沉淀
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类免疫缺陷病毒1; 图 s1k
Kyei G, Meng S, Ramani R, Niu A, Lagisetti C, Webb T, et al. Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency. MBio. 2018;9: pubmed 出版商
  • 免疫沉淀; 人类; 图 4
Glenewinkel F, Cohen M, King C, Kaspar S, Bamberg Lemper S, Mymryk J, et al. The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2. Sci Rep. 2016;6:28241 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 1
Booiman T, Loukachov V, van Dort K, van t Wout A, Kootstra N. DYRK1A Controls HIV-1 Replication at a Transcriptional Level in an NFAT Dependent Manner. PLoS ONE. 2015;10:e0144229 pubmed 出版商
  • 免疫沉淀; 小鼠; 10 ug
  • 免疫印迹; 小鼠
Grau C, Arató K, Fernández Fernández J, Valderrama A, Sindreu C, Fillat C, et al. DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors. Front Cell Neurosci. 2014;8:331 pubmed 出版商
  • 免疫印迹; 小鼠; 1:250
Janel N, Sarazin M, Corlier F, Corne H, de Souza L, Hamelin L, et al. Plasma DYRK1A as a novel risk factor for Alzheimer's disease. Transl Psychiatry. 2014;4:e425 pubmed 出版商
Kisaka J, Ratner L, Kyei G. The Dual-Specificity Kinase DYRK1A Modulates the Levels of Cyclin L2 To Control HIV Replication in Macrophages. J Virol. 2020;94: pubmed 出版商
Altafaj X, Martin E, Ortiz Abalia J, Valderrama A, Lao Peregrín C, Dierssen M, et al. Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome. Neurobiol Dis. 2013;52:117-27 pubmed 出版商
Spellman C, Ahmed M, Dubach D, Gardiner K. Expression of trisomic proteins in Down syndrome model systems. Gene. 2013;512:219-25 pubmed 出版商
Guo X, Kesimer M, Tolun G, Zheng X, Xu Q, Lu J, et al. The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Sci Rep. 2012;2:640 pubmed 出版商
Planque C, Dairou J, Noll C, Bui L, Ripoll C, Guedj F, et al. Mice deficient in cystathionine beta synthase display increased Dyrk1A and SAHH activities in brain. J Mol Neurosci. 2013;50:1-6 pubmed 出版商
Malinge S, Bliss Moreau M, Kirsammer G, Diebold L, Chlon T, Gurbuxani S, et al. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest. 2012;122:948-62 pubmed 出版商
Guedj F, Pereira P, Najas S, Barallobre M, Chabert C, Souchet B, et al. DYRK1A: a master regulatory protein controlling brain growth. Neurobiol Dis. 2012;46:190-203 pubmed 出版商
Park J, Sung J, Park J, Song W, Chang S, Chung K. Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP. J Cell Sci. 2012;125:67-80 pubmed 出版商
Ahmed M, Sturgeon X, Ellison M, Davisson M, Gardiner K. Loss of correlations among proteins in brains of the Ts65Dn mouse model of down syndrome. J Proteome Res. 2012;11:1251-63 pubmed 出版商
Sheppard O, Plattner F, Rubin A, Slender A, Linehan J, Brandner S, et al. Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiol Aging. 2012;33:828.e31-44 pubmed 出版商
Toiber D, Azkona G, Ben Ari S, Toran N, Soreq H, Dierssen M. Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations. Neurobiol Dis. 2010;40:348-59 pubmed 出版商
Guo X, Williams J, Schug T, Li X. DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. J Biol Chem. 2010;285:13223-32 pubmed 出版商
Raaf L, Noll C, Cherifi M, Benazzoug Y, Delabar J, Janel N. Hyperhomocysteinemia-induced Dyrk1a downregulation results in cardiomyocyte hypertrophy in rats. Int J Cardiol. 2010;145:306-307 pubmed 出版商
Noll C, Planque C, Ripoll C, Guedj F, Diez A, Ducros V, et al. DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase. PLoS ONE. 2009;4:e7540 pubmed 出版商
Lee Y, Ha J, Kim H, Kim Y, Chang E, Song W, et al. Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis. J Biol Chem. 2009;284:33343-51 pubmed 出版商
Scales T, Lin S, Kraus M, Goold R, Gordon Weeks P. Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons. J Cell Sci. 2009;122:2424-35 pubmed 出版商
Guedj F, Sebrie C, Rivals I, Ledru A, Paly E, Bizot J, et al. Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A. PLoS ONE. 2009;4:e4606 pubmed 出版商
Hamelet J, Noll C, Ripoll C, Paul J, Janel N, Delabar J. Effect of hyperhomocysteinemia on the protein kinase DYRK1A in liver of mice. Biochem Biophys Res Commun. 2009;378:673-7 pubmed 出版商
Aranda S, Alvarez M, Turró S, Laguna A, De La Luna S. Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A. Mol Cell Biol. 2008;28:5899-911 pubmed 出版商
产品信息
目录号码 :
H00001859-M01
产品名称 :
DYRK1A单克隆抗体(M01), 克隆7D10
产品描述 :
Mouse monoclonal antibody raised against a partial recombinant DYRK1A.
克隆名称 :
7D10
抗体亚型 :
IgG2b Kappa
基因名称 :
DYRK1A
基因别名 :
DYRK DYRK1 HP86 MNB MNBH
基因描述 :
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
GenBank登录号 :
NM_001396
免疫原 :
DYRK1A (NP_001387, 674 a.a. ~ 763 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
免疫原序列蛋白序列 :
NQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQET
GIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMT
GVCVQQSPVASS
蛋白登录号 :
NP_001387
储存缓冲液 :
在1x PBS, pH值7.4
储存说明 :
储存在-20℃或更低。分装以避免反复冻融
质量控制试验 :
抗体能识别重组蛋白
类型克隆性 :
抗体
宿主物种 :
小鼠
抗原物种靶物种 :
人类
物种活性交叉活性 :
人类, 小鼠, 大鼠
应用 :
WB-Ce,S-ELISA,ELISA,WB-Re
规格 :
100微克
开始日期 :
4/18/08
更新日期 :
11/15/13 18:40
公司信息
亚诺法生技股份有限公司
台湾台北市內湖區洲子街108號9樓
sales@abnova.com
https://www.abnova.com
886-2-87511888