产品简要
公司名称 :
亚诺法生技股份有限公司
产品类型 :
抗体
产品名称 :
STIM1单克隆抗体(M01), 克隆5A2
目录 :
H00006786-M01
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5A2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 3c
Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, et al. BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival. Cell Death Differ. 2016;23:358-68 pubmed 出版商
  • 免疫组化; 人类; 1:75
Steinbeck J, Henke N, Opatz J, Gruszczynska Biegala J, Schneider L, Theiss S, et al. Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy. Exp Neurol. 2011;232:185-94 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Schuhmann M, Stegner D, Berna Erro A, Bittner S, Braun A, Kleinschnitz C, et al. Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation. J Immunol. 2010;184:1536-42 pubmed 出版商
Henke N, Albrecht P, Pfeiffer A, Toutzaris D, Zanger K, Methner A. Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress. J Biol Chem. 2012;287:42042-52 pubmed 出版商
Halloran S, Launoy G, Zappa M. European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Faecal occult blood testing. Endoscopy. 2012;44 Suppl 3:SE65-87 pubmed
Elvers M, Herrmann A, Seizer P, Münzer P, Beck S, Schonberger T, et al. Intracellular cyclophilin A is an important Ca(2+) regulator in platelets and critically involved in arterial thrombus formation. Blood. 2012;120:1317-26 pubmed 出版商
Eylenstein A, Schmidt S, Gu S, Yang W, Schmid E, Schmidt E, et al. Transcription factor NF-?B regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions. J Biol Chem. 2012;287:2719-30 pubmed 出版商
Kiviluoto S, Decuypere J, De Smedt H, Missiaen L, Parys J, Bultynck G. STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function. Skelet Muscle. 2011;1:16 pubmed 出版商
Saitoh N, Oritani K, Saito K, Yokota T, Ichii M, Sudo T, et al. Identification of functional domains and novel binding partners of STIM proteins. J Cell Biochem. 2011;112:147-56 pubmed 出版商
Pani B, Ong H, Brazer S, Liu X, Rauser K, Singh B, et al. Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1. Proc Natl Acad Sci U S A. 2009;106:20087-92 pubmed 出版商
Beyersdorf N, Braun A, Vögtle T, Varga Szabo D, Galdos R, Kissler S, et al. STIM1-independent T cell development and effector function in vivo. J Immunol. 2009;182:3390-7 pubmed 出版商
Wu F, Wang P, Young L, Lai R, Li L. Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry. Am J Pathol. 2009;174:361-70 pubmed 出版商
Braun A, Gessner J, Varga Szabo D, Syed S, Konrad S, Stegner D, et al. STIM1 is essential for Fcgamma receptor activation and autoimmune inflammation. Blood. 2009;113:1097-104 pubmed 出版商
Varga Szabo D, Braun A, Kleinschnitz C, Bender M, Pleines I, Pham M, et al. The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction. J Exp Med. 2008;205:1583-91 pubmed 出版商
Pani B, Ong H, Liu X, Rauser K, Ambudkar I, Singh B. Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE). J Biol Chem. 2008;283:17333-40 pubmed 出版商
Alicia S, Angélica Z, Carlos S, Alfonso S, Vaca L. STIM1 converts TRPC1 from a receptor-operated to a store-operated channel: moving TRPC1 in and out of lipid rafts. Cell Calcium. 2008;44:479-91 pubmed 出版商
Grosse J, Braun A, Varga Szabo D, Beyersdorf N, Schneider B, Zeitlmann L, et al. An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice. J Clin Invest. 2007;117:3540-50 pubmed
产品信息
目录号码 :
H00006786-M01
产品名称 :
STIM1单克隆抗体(M01), 克隆5A2
产品描述 :
小鼠单克隆抗体抗a全长重组STIM1
克隆名称 :
5A2
抗体亚型 :
IgG2a Kappa
基因名称 :
STIM1
基因别名 :
D11S4896E GOK
基因描述 :
stromal interaction molecule 1
GenBank登录号 :
BC021300
免疫原 :
STIM1 (AAH21300, 24 a.a. ~ 685 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
免疫原序列蛋白序列 :
SHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEK
LSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDP
TVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQW
LITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGAVL
KMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVV
SIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQS
LHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE
AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL
ESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLL
VAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAK
QALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVA
ALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQ
SPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDR
QRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVHPGSLV
EKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGS
PHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHL
AGKKAVAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK
蛋白登录号 :
AAH21300
储存缓冲液 :
在1x PBS, pH值7.4
储存说明 :
储存在-20℃或更低。分装以避免反复冻融
质量控制试验 :
抗体能识别重组蛋白
类型克隆性 :
抗体
宿主物种 :
小鼠
抗原物种靶物种 :
人类
物种活性交叉活性 :
人类, 大鼠
应用 :
WB-Ti,S-ELISA,ELISA,WB-Re,IF,IHC-P
规格 :
100微克
开始日期 :
10/10/06
更新日期 :
11/15/13 18:29
公司信息
亚诺法生技股份有限公司
台湾台北市內湖區洲子街108號9樓
sales@abnova.com
https://www.abnova.com
886-2-87511888