产品简要
公司名称 :
亚诺法生技股份有限公司
产品类型 :
抗体
产品名称 :
泛肽结合蛋白p62单克隆抗体(M01), 克隆2C11
目录 :
H00008878-M01
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2C11
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他
文章摘录数: 95
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:5000
Ormeño F, Hormazabal J, Moreno J, Riquelme F, Rios J, Criollo A, et al. Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation. Front Mol Neurosci. 2020;13:19 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Wang S, Ni H, Chao X, Wang H, Bridges B, Kumer S, et al. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis. Autophagy. 2019;15:1954-1969 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed 出版商
  • 免疫印迹; 人类; 图 4f
Potes Y, de Luxán Delgado B, Rodríguez González S, Guimarães M, Solano J, Fernández Fernández M, et al. Overweight in elderly people induces impaired autophagy in skeletal muscle. Free Radic Biol Med. 2017;110:31-41 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Zhang Y, Nguyen D, Olzomer E, Poon G, Cole N, Puvanendran A, et al. Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Cell Chem Biol. 2017;24:471-480.e4 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3d
Cooper H, Yang Y, Ylikallio E, Khairullin R, Woldegebriel R, Lin K, et al. ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. Hum Mol Genet. 2017;26:1432-1443 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 2A
Redmann M, Wani W, Volpicelli Daley L, Darley Usmar V, Zhang J. Trehalose does not improve neuronal survival on exposure to alpha-synuclein pre-formed fibrils. Redox Biol. 2017;11:429-437 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
  • 免疫印迹; 人类; 图 5j
Pietrocola F, Demont Y, Castoldi F, Enot D, Durand S, Semeraro M, et al. Metabolic effects of fasting on human and mouse blood in vivo. Autophagy. 2017;13:567-578 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4a
Sambri I, D Alessio R, Ezhova Y, Giuliano T, Sorrentino N, Cacace V, et al. Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases. EMBO Mol Med. 2017;9:112-132 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s10b
Newberry E, Xie Y, Kennedy S, Graham M, Crooke R, Jiang H, et al. Prevention of hepatic fibrosis with liver microsomal triglyceride transfer protein deletion in liver fatty acid binding protein null mice. Hepatology. 2017;65:836-852 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3f
Fan Y, Wang N, Rocchi A, Zhang W, Vassar R, Zhou Y, et al. Identification of natural products with neuronal and metabolic benefits through autophagy induction. Autophagy. 2017;13:41-56 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8a
Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 2
Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1
Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed 出版商
  • 其他; 人类; 图 4
Puvirajesinghe T, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun. 2016;7:10318 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s13
  • 免疫细胞化学; 小鼠; 图 s1
  • 免疫印迹; 小鼠; 1:3000; 图 s4
Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed 出版商
  • 免疫印迹; 人类; 图 7g
Nezich C, Wang C, Fogel A, Youle R. MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5. J Cell Biol. 2015;210:435-50 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Hermanova I, Arruabarrena Aristorena A, Valis K, Nůsková H, Alberich Jorda M, Fiser K, et al. Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells. Leukemia. 2016;30:209-18 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Shi Y, Tan S, Ng S, Zhou J, Yang N, Koo G, et al. Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy. Autophagy. 2015;11:769-84 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500
Porta S, Kwong L, Trojanowski J, Lee V. Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases. J Neuropathol Exp Neurol. 2015;74:380-7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2
  • 免疫印迹; 人类; 1:5000; 图 1
Pedro J, Wei Y, Sica V, Maiuri M, Zou Z, Kroemer G, et al. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Autophagy. 2015;11:452-9 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200
  • 免疫印迹; 小鼠
Ni H, Bhakta A, Wang S, Li Z, Manley S, Huang H, et al. Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice. PLoS ONE. 2014;9:e115849 pubmed 出版商
  • 免疫印迹; 小鼠
Manley S, Ni H, Williams J, Kong B, DiTacchio L, Guo G, et al. Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity. Redox Biol. 2014;2:991-1002 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
  • 免疫印迹; 小鼠
Barnard R, Wittenburg L, Amaravadi R, Gustafson D, Thorburn A, Thamm D. Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma. Autophagy. 2014;10:1415-25 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Karanasios E, Stapleton E, Manifava M, Ktistakis N. Imaging autophagy. Curr Protoc Cytom. 2014;69:12.34.1-12.34.16 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed 出版商
  • 免疫印迹; 小鼠
de Luxán Delgado B, Caballero B, Potes Y, Rubio González A, Rodríguez I, Gutiérrez Rodríguez J, et al. Melatonin administration decreases adipogenesis in the liver of ob/ob mice through autophagy modulation. J Pineal Res. 2014;56:126-33 pubmed 出版商
  • 免疫印迹; 小鼠
Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-1825 pubmed 出版商
Anandhan A, Nguyen N, Syal A, Dreher L, Dodson M, Zhang D, et al. NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice. Aging Dis. 2021;12:964-982 pubmed 出版商
Wang B, Maxwell B, Joo J, Gwon Y, Messing J, Mishra A, et al. ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. Mol Cell. 2019;74:742-757.e8 pubmed 出版商
Vargas J, Wang C, Bunker E, Hao L, Maric D, Schiavo G, et al. Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy. Mol Cell. 2019;74:347-362.e6 pubmed 出版商
Janssen A, Katrukha E, van Straaten W, Verlhac P, Reggiori F, Kapitein L. Probing aggrephagy using chemically-induced protein aggregates. Nat Commun. 2018;9:4245 pubmed 出版商
Henderson M, Peng C, Trojanowski J, Lee V. LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons. Acta Neuropathol Commun. 2018;6:45 pubmed 出版商
Li Y, Chao X, Yang L, Lu Q, Li T, Ding W, et al. Impaired Fasting-Induced Adaptive Lipid Droplet Biogenesis in Liver-Specific Atg5-Deficient Mouse Liver Is Mediated by Persistent Nuclear Factor-Like 2 Activation. Am J Pathol. 2018;188:1833-1846 pubmed 出版商
Brewer R, Collins H, Berry R, Brahma M, Tirado B, Peliciari Garcia R, et al. Temporal partitioning of adaptive responses of the murine heart to fasting. Life Sci. 2018;197:30-39 pubmed 出版商
Baron O, Boudi A, Dias C, Schilling M, Nölle A, Vizcay Barrena G, et al. Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration. Curr Biol. 2017;27:3626-3642.e6 pubmed 出版商
Liu S, Jiang Y, Ballou L, Zong W, Lin R. Activation of Gαq in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy. J Cardiovasc Pharmacol. 2017;69:198-211 pubmed 出版商
Redmann M, Benavides G, Berryhill T, Wani W, Ouyang X, Johnson M, et al. Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons. Redox Biol. 2017;11:73-81 pubmed 出版商
Jin H, Hong S, Park J, Chang Y, Hong Y, Park I, et al. Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors. Sci Rep. 2016;6:28945 pubmed 出版商
Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed 出版商
Lapash Daniels C, Paffenroth E, Austin E, Glebov K, Lewis D, Walter J, et al. Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease. PLoS ONE. 2015;10:e0138132 pubmed 出版商
Yang H, Peng Y, Ni H, Li Y, Shi Y, Ding W, et al. Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth. PLoS ONE. 2015;10:e0130953 pubmed 出版商
Li P, Shi J, He Q, Hu Q, Wang Y, Zhang L, et al. Streptococcus pneumoniae induces autophagy through the inhibition of the PI3K-I/Akt/mTOR pathway and ROS hypergeneration in A549 cells. PLoS ONE. 2015;10:e0122753 pubmed 出版商
Morgan M, Gamez G, Menke C, Hernandez A, Thorburn J, Gidan F, et al. Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent. Autophagy. 2014;10:1814-26 pubmed 出版商
Chang M, Patel V, Gwede M, Morgado M, Tomasevich K, Fong E, et al. IL-1? induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells. J Cell Biochem. 2014;115:2188-97 pubmed 出版商
B chir W, Chaveroux C, Carraro V, Averous J, Maurin A, Jousse C, et al. Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation. Cell Signal. 2014;26:1385-91 pubmed 出版商
Macvicar T, Lane J. Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation. J Cell Sci. 2014;127:2313-25 pubmed 出版商
Manley S, Ni H, Kong B, Apte U, Guo G, Ding W. Suppression of autophagic flux by bile acids in hepatocytes. Toxicol Sci. 2014;137:478-90 pubmed 出版商
Mizielinska S, Lashley T, Norona F, Clayton E, Ridler C, Fratta P, et al. C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci. Acta Neuropathol. 2013;126:845-57 pubmed 出版商
Jang B, Choi B, Kim J, Kim M, Sohn M, Suh S. Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation. PLoS ONE. 2013;8:e76466 pubmed 出版商
Chang M, Morgado M, Warren C, Hinton C, Farach Carson M, DELK N. p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines. Prostate. 2014;74:149-63 pubmed 出版商
Tardif N, Klaude M, Lundell L, Thorell A, Rooyackers O. Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients. Am J Clin Nutr. 2013;98:1485-92 pubmed 出版商
B chir W, Maurin A, Carraro V, Averous J, Jousse C, Muranishi Y, et al. The eIF2?/ATF4 pathway is essential for stress-induced autophagy gene expression. Nucleic Acids Res. 2013;41:7683-99 pubmed 出版商
Cabrera S, Fernández A, Mariño G, Aguirre A, Suarez M, Español Y, et al. ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis. Autophagy. 2013;9:1188-200 pubmed 出版商
Betin V, Singleton B, Parsons S, Anstee D, Lane J. Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy. 2013;9:881-93 pubmed 出版商
Joubert R, Vignaud A, Le M, Moal C, Messaddeq N, Buj Bello A. Site-specific Mtm1 mutagenesis by an AAV-Cre vector reveals that myotubularin is essential in adult muscle. Hum Mol Genet. 2013;22:1856-66 pubmed 出版商
Pan J, Fan Y, Gandhirajan R, Madesh M, Zong W. Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis. J Biol Chem. 2013;288:2952-63 pubmed 出版商
Fetalvero K, Yu Y, Goetschkes M, Liang G, Valdez R, Gould T, et al. Defective autophagy and mTORC1 signaling in myotubularin null mice. Mol Cell Biol. 2013;33:98-110 pubmed 出版商
Zhang Y, Yang N, Zhou F, Shen T, Duan T, Zhou J, et al. (-)-Epigallocatechin-3-gallate induces non-apoptotic cell death in human cancer cells via ROS-mediated lysosomal membrane permeabilization. PLoS ONE. 2012;7:e46749 pubmed 出版商
Liao C, Ho M, Liang S, Liang C. Recombinant protein rVP1 upregulates BECN1-independent autophagy, MAPK1/3 phosphorylation and MMP9 activity via WIPI1/WIPI2 to promote macrophage migration. Autophagy. 2013;9:5-19 pubmed 出版商
Vandergaast R, Fredericksen B. West Nile virus (WNV) replication is independent of autophagy in mammalian cells. PLoS ONE. 2012;7:e45800 pubmed 出版商
Williams J, Thomas A, Li G, Kong B, Zhan L, Inaba Y, et al. Tissue specific induction of p62/Sqstm1 by farnesoid X receptor. PLoS ONE. 2012;7:e43961 pubmed 出版商
Kharaziha P, De Raeve H, Fristedt C, Li Q, Gruber A, Johnsson P, et al. Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model. Cancer Res. 2012;72:5348-62 pubmed 出版商
Lai A, McLaurin J. Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease. Biochim Biophys Acta. 2012;1822:1629-37 pubmed 出版商
Hagemann T, Jobe E, Messing A. Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival. PLoS ONE. 2012;7:e37304 pubmed 出版商
Marchbank K, Waters S, Roberts R, Solomon E, Whitehouse C. MAP1B Interaction with the FW Domain of the Autophagic Receptor Nbr1 Facilitates Its Association to the Microtubule Network. Int J Cell Biol. 2012;2012:208014 pubmed 出版商
Ni H, Boggess N, McGill M, Lebofsky M, Borude P, Apte U, et al. Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury. Toxicol Sci. 2012;127:438-50 pubmed 出版商
Menon S, Yecies J, Zhang H, Howell J, Nicholatos J, Harputlugil E, et al. Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice. Sci Signal. 2012;5:ra24 pubmed 出版商
Durieux A, Vassilopoulos S, Laine J, Fraysse B, Brinas L, Prudhon B, et al. A centronuclear myopathy--dynamin 2 mutation impairs autophagy in mice. Traffic. 2012;13:869-79 pubmed 出版商
Ghazi Noori S, Froud K, Mizielinska S, Powell C, Smidak M, Fernández de Marco M, et al. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain. 2012;135:819-32 pubmed 出版商
Jaber N, Dou Z, Chen J, Catanzaro J, Jiang Y, Ballou L, et al. Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci U S A. 2012;109:2003-8 pubmed 出版商
Kharaziha P, Rodriguez P, Li Q, Rundqvist H, Björklund A, Augsten M, et al. Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells. Cell Death Dis. 2012;3:e262 pubmed 出版商
Chen J, Xavier S, Moskowitz Kassai E, Chen R, Lu C, Sanduski K, et al. Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. Am J Pathol. 2012;180:973-83 pubmed 出版商
Krüger U, Wang Y, Kumar S, Mandelkow E. Autophagic degradation of tau in primary neurons and its enhancement by trehalose. Neurobiol Aging. 2012;33:2291-305 pubmed 出版商
Zois C, Giatromanolaki A, Sivridis E, Papaiakovou M, Kainulainen H, Koukourakis M. "Autophagic flux" in normal mouse tissues: focus on endogenous LC3A processing. Autophagy. 2011;7:1371-8 pubmed 出版商
Deng H, Chen W, Hong S, Boycott K, Gorrie G, Siddique N, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 2011;477:211-5 pubmed 出版商
Levy J, Thorburn A. Modulation of pediatric brain tumor autophagy and chemosensitivity. J Neurooncol. 2012;106:281-90 pubmed 出版商
Ng S, Wu Y, Chen B, Zhou J, Shen H. Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress. Autophagy. 2011;7:1173-86 pubmed 出版商
Kovacs J, Li C, Yang Q, Li G, Garcia I, Ju S, et al. Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery. Cell Death Differ. 2012;19:144-52 pubmed 出版商
Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011;25:717-29 pubmed 出版商
Zois C, Giatromanolaki A, Kainulainen H, Botaitis S, Torvinen S, Simopoulos C, et al. Lung autophagic response following exposure of mice to whole body irradiation, with and without amifostine. Biochem Biophys Res Commun. 2011;404:552-8 pubmed 出版商
Whitehouse C, Waters S, Marchbank K, Horner A, McGowan N, Jovanovic J, et al. Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity. Proc Natl Acad Sci U S A. 2010;107:12913-8 pubmed 出版商
Deng H, Zhai H, Bigio E, Yan J, Fecto F, Ajroud K, et al. FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis. Ann Neurol. 2010;67:739-48 pubmed 出版商
Wang B, Ling S, Lin W. 14-3-3Tau regulates Beclin 1 and is required for autophagy. PLoS ONE. 2010;5:e10409 pubmed 出版商
Lee H, Mattei L, Steinberg B, Alberts P, Lee Y, Chervonsky A, et al. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010;32:227-39 pubmed 出版商
Wu Y, Tan H, Shui G, Bauvy C, Huang Q, Wenk M, et al. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem. 2010;285:10850-61 pubmed 出版商
Mardakheh F, Yekezare M, Machesky L, Heath J. Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. J Cell Biol. 2009;187:265-77 pubmed 出版商
Ferguson C, Lenk G, Meisler M. Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2. Hum Mol Genet. 2009;18:4868-78 pubmed 出版商
Gal J, Strom A, Kwinter D, Kilty R, Zhang J, Shi P, et al. Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. J Neurochem. 2009;111:1062-73 pubmed 出版商
Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T. Monitoring autophagic degradation of p62/SQSTM1. Methods Enzymol. 2009;452:181-97 pubmed 出版商
Jung H, Chung K, Won Kim J, Kim J, Komatsu M, Tanaka K, et al. Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab. 2008;8:318-24 pubmed 出版商
产品信息
目录号码 :
H00008878-M01
产品名称 :
泛肽结合蛋白p62单克隆抗体(M01), 克隆2C11
产品描述 :
小鼠单克隆抗体抗a全长重组泛肽结合蛋白p62
克隆名称 :
2C11
抗体亚型 :
IgG2a kappa
基因名称 :
泛肽结合蛋白p62
基因别名 :
A170 OSIL PDB3 ZIP3 p60 p62 p62B
基因描述 :
sequestosome 1
GenBank登录号 :
BC003139
免疫原 :
SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
免疫原序列蛋白序列 :
MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAA
GPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFS
SDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEA
PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG
KGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGW
PGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSV
NFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSP
ESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMR
KIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTG
ELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEA
DPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALD
TIQYSKHPPPL
蛋白登录号 :
AAH03139.1
储存缓冲液 :
在1x PBS, pH值7.4
储存说明 :
储存在-20℃或更低。分装以避免反复冻融
质量控制试验 :
抗体能识别重组蛋白
类型克隆性 :
抗体
宿主物种 :
小鼠
抗原物种靶物种 :
人类
物种活性交叉活性 :
人类, 小鼠
应用 :
S-ELISA,ELISA,WB-Re,IF
规格 :
100微克
开始日期 :
10/10/06
更新日期 :
11/15/13 18:29
公司信息
亚诺法生技股份有限公司
台湾台北市內湖區洲子街108號9樓
sales@abnova.com
https://www.abnova.com
886-2-87511888