出版应用/物种/样本/稀释 | 参考文献 |
---|
| Watanabe R, Higashi S, Nonaka T, Kawakami I, Oshima K, Niizato K, et al. Intracellular dynamics of Ataxin-2 in the human brains with normal and frontotemporal lobar degeneration with TDP-43 inclusions. Acta Neuropathol Commun. 2020;8:176 pubmed 出版商
|
| Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed 出版商
|
- 免疫组化-石蜡切片; 人类; 1:500; 图 3a
| van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, et al. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Hum Mutat. 2017;38:297-309 pubmed 出版商
|
- 免疫组化; fruit fly ; 1:500; 图 7g
| Matsukawa K, Hashimoto T, Matsumoto T, Ihara R, Chihara T, Miura M, et al. Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43. J Biol Chem. 2016;291:23464-23476 pubmed
|
| Gelpi E, Hoftberger R, Graus F, Ling H, Holton J, Dawson T, et al. Neuropathological criteria of anti-IgLON5-related tauopathy. Acta Neuropathol. 2016;132:531-43 pubmed 出版商
|
- 免疫细胞化学; 人类; 图 5
- 免疫印迹; 人类; 图 2a
| De Marco G, Lomartire A, Calvo A, Risso A, De Luca E, Mostert M, et al. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution. Neuropathol Appl Neurobiol. 2017;43:133-153 pubmed 出版商
|
| Williams K, Topp S, Yang S, Smith B, Fifita J, Warraich S, et al. CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia. Nat Commun. 2016;7:11253 pubmed 出版商
|
- 免疫细胞化学; 人类; 1:1000
- 免疫印迹; 人类; 1:2000
| Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed 出版商
|
- 免疫组化-石蜡切片; 人类; 1:100; 图 5
| Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, et al. REST and stress resistance in ageing and Alzheimer's disease. Nature. 2014;507:448-54 pubmed 出版商
|
| De Marco G, Lomartire A, Mandili G, Lupino E, Buccinnà B, Ramondetti C, et al. Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. Biochim Biophys Acta. 2014;1843:725-34 pubmed 出版商
|
| Fiesel F, Voigt A, Weber S, Van den Haute C, Waldenmaier A, Görner K, et al. Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J. 2010;29:209-21 pubmed 出版商
|
| Kovacs G, Majtenyi K, Spina S, Murrell J, Gelpi E, Hoftberger R, et al. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. J Neuropathol Exp Neurol. 2008;67:963-75 pubmed 出版商
|
| Lin W, Dickson D. Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases. Acta Neuropathol. 2008;116:205-13 pubmed 出版商
|
| Igaz L, Kwong L, Xu Y, Truax A, Uryu K, Neumann M, et al. Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol. 2008;173:182-94 pubmed 出版商
|
| Foulds P, McAuley E, Gibbons L, Davidson Y, Pickering Brown S, Neary D, et al. TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration. Acta Neuropathol. 2008;116:141-6 pubmed 出版商
|
| Ma X, Prudencio M, Koike Y, Vatsavayai S, Kim G, Harbinski F, et al. TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature. 2022;603:124-130 pubmed 出版商
|
| Ximelis T, Marín Moreno A, Espinosa J, Eraña H, Charco J, Hernandez I, et al. Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease. Alzheimers Res Ther. 2021;13:176 pubmed 出版商
|
| Yagensky O, Kohansal Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, et al. Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. elife. 2019;8: pubmed 出版商
|
| Fang M, Markmiller S, Vu A, Javaherian A, Dowdle W, Jolivet P, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019;: pubmed 出版商
|
| Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, et al. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol. 2019;137:919-937 pubmed 出版商
|
| Solomon D, Stepto A, Au W, Adachi Y, Diaper D, Hall R, et al. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration. Brain. 2018;141:2908-2924 pubmed 出版商
|
| Archbold H, Jackson K, Arora A, Weskamp K, Tank E, Li X, et al. TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia. Sci Rep. 2018;8:4606 pubmed 出版商
|
| Feneberg E, Gray E, Ansorge O, Talbot K, Turner M. Towards a TDP-43-Based Biomarker for ALS and FTLD. Mol Neurobiol. 2018;55:7789-7801 pubmed 出版商
|
| Gregory J, Whiten D, Brown R, Barros T, Kumita J, Yerbury J, et al. Clusterin protects neurons against intracellular proteotoxicity. Acta Neuropathol Commun. 2017;5:81 pubmed 出版商
|
| Koyama A, Sugai A, Kato T, Ishihara T, Shiga A, Toyoshima Y, et al. Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43. Nucleic Acids Res. 2016;44:5820-36 pubmed 出版商
|
| Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, et al. ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS ONE. 2013;8:e81170 pubmed 出版商
|
| Nishimoto Y, Nakagawa S, Hirose T, Okano H, Takao M, Shibata S, et al. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain. 2013;6:31 pubmed 出版商
|
| Bosque P, Boyer P, Mishra P. A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration. PLoS ONE. 2013;8:e62301 pubmed 出版商
|
| Tong J, Huang C, Bi F, Wu Q, Huang B, Zhou H. XBP1 depletion precedes ubiquitin aggregation and Golgi fragmentation in TDP-43 transgenic rats. J Neurochem. 2012;123:406-16 pubmed 出版商
|
| Lopez Gonzalez I, Carmona M, Blanco R, Luna Munoz J, Martínez Mandonado A, Mena R, et al. Characterization of thorn-shaped astrocytes in white matter of temporal lobe in Alzheimer's disease brains. Brain Pathol. 2013;23:144-53 pubmed 出版商
|
| Verstraete E, Kuiperij H, van Blitterswijk M, Veldink J, Schelhaas H, van den Berg L, et al. TDP-43 plasma levels are higher in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2012;13:446-51 pubmed 出版商
|
| Gelpi E, Soler Insa J, Parchi P, Saverioni D, Yague J, Nos C, et al. Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex. Neuropathology. 2013;33:204-8 pubmed 出版商
|
| Colom Cadena M, Gelpi E, Marti M, Charif S, Dols Icardo O, Blesa R, et al. MAPT H1 haplotype is associated with enhanced ?-synuclein deposition in dementia with Lewy bodies. Neurobiol Aging. 2013;34:936-42 pubmed 出版商
|
| Vilas D, Marti M, Botta Orfila T, Colom Cadena M, Gelpi E. Pick's pathology in Parkinson's disease with dementia. Neuropathol Appl Neurobiol. 2012;38:737-43 pubmed 出版商
|
| Echávarri C, Burgmans S, Caballero M, Garcia Bragado F, Verhey F, Uylings H. Co-occurrence of different pathologies in dementia: implications for dementia diagnosis. J Alzheimers Dis. 2012;30:909-17 pubmed 出版商
|
| Herman A, Khandelwal P, Rebeck G, Moussa C. Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models. Exp Neurol. 2012;235:297-305 pubmed 出版商
|
| Troakes C, Maekawa S, Wijesekera L, Rogelj B, Siklós L, Bell C, et al. An MND/ALS phenotype associated with C9orf72 repeat expansion: abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline. Neuropathology. 2012;32:505-14 pubmed 出版商
|
| Dayton R, Wang D, Cain C, Schrott L, Ramirez J, King M, et al. Frontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus. Exp Neurol. 2012;233:807-14 pubmed 出版商
|
| Huang C, Tong J, Bi F, Zhou H, Xia X. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats. J Clin Invest. 2012;122:107-18 pubmed 出版商
|
| Tsuji H, Nonaka T, Yamashita M, Masuda Suzukake M, Kametani F, Akiyama H, et al. Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Biochem Biophys Res Commun. 2012;417:116-21 pubmed 出版商
|
| Fiesel F, Weber S, Supper J, Zell A, Kahle P. TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR. Nucleic Acids Res. 2012;40:2668-82 pubmed 出版商
|
| Antonell A, Gelpi E, Sanchez Valle R, Martinez R, Molinuevo J, Lladó A. Breakpoint sequence analysis of an A?PP locus duplication associated with autosomal dominant Alzheimer's disease and severe cerebral amyloid angiopathy. J Alzheimers Dis. 2012;28:303-8 pubmed 出版商
|
| Thom M, Liu J, Thompson P, Phadke R, Narkiewicz M, Martinian L, et al. Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study. Brain. 2011;134:2969-81 pubmed 出版商
|
| Wang J, Brent J, Tomlinson A, Shneider N, McCabe B. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest. 2011;121:4118-26 pubmed 出版商
|
| Swarup V, Phaneuf D, Bareil C, Robertson J, Rouleau G, Kriz J, et al. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain. 2011;134:2610-26 pubmed 出版商
|
| Martínez Sáez E, Gelpi E, Rey M, Ferrer I, Ribalta T, Botta Orfila T, et al. Hirano body-rich subtypes of Creutzfeldt-Jakob disease. Neuropathol Appl Neurobiol. 2012;38:153-61 pubmed 出版商
|
| Azizi A, Li L, Strobel T, Chen W, Slavc I, Lubec G. Identification of c-myc-dependent proteins in the medulloblastoma cell line D425Med. Amino Acids. 2012;42:2149-63 pubmed 出版商
|
| López Hernández T, Sirisi S, Capdevila Nortes X, Montolio M, Fernández Dueñas V, Scheper G, et al. Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. Hum Mol Genet. 2011;20:3266-77 pubmed 出版商
|
| Rusina R, Kovacs G, Fiala J, Hort J, Ridzon P, Holmerová I, et al. FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases. BMC Neurol. 2011;11:50 pubmed 出版商
|
| Mundiñano I, Caballero M, Ordóñez C, Hernandez M, Dicaudo C, Marcilla I, et al. Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders. Acta Neuropathol. 2011;122:61-74 pubmed 出版商
|
| Pikkarainen M, Hartikainen P, Soininen H, Alafuzoff I. Distribution and pattern of pathology in subjects with familial or sporadic late-onset cerebellar ataxia as assessed by p62/sequestosome immunohistochemistry. Cerebellum. 2011;10:720-31 pubmed 出版商
|
| Hartikainen P, Pikkarainen M, Hanninen T, Soininen H, Alafuzoff I. Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions. Neuropathology. 2012;32:60-8 pubmed 出版商
|
| Che M, Jiang Y, Xie Y, Jiang L, Hu H. Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing. FASEB J. 2011;25:2344-53 pubmed 出版商
|
| Tian T, Huang C, Tong J, Yang M, Zhou H, Xia X. TDP-43 potentiates alpha-synuclein toxicity to dopaminergic neurons in transgenic mice. Int J Biol Sci. 2011;7:234-43 pubmed
|
| Herman A, Khandelwal P, Stanczyk B, Rebeck G, Moussa C. ?-amyloid triggers ALS-associated TDP-43 pathology in AD models. Brain Res. 2011;1386:191-9 pubmed 出版商
|
| Lashley T, Holton J, Revesz T. TDP-43 pathology may occur in the BRI2 gene-related dementias. Acta Neuropathol. 2011;121:559-60 pubmed 出版商
|
| Rauramaa T, Pikkarainen M, Englund E, Ince P, Jellinger K, Paetau A, et al. TAR-DNA binding protein-43 and alterations in the hippocampus. J Neural Transm (Vienna). 2011;118:683-9 pubmed 出版商
|
| Noto Y, Shibuya K, Sato Y, Kanai K, Misawa S, Sawai S, et al. Elevated CSF TDP-43 levels in amyotrophic lateral sclerosis: specificity, sensitivity, and a possible prognostic value. Amyotroph Lateral Scler. 2011;12:140-3 pubmed 出版商
|
| De Marco G, Lupino E, Calvo A, Moglia C, Buccinnà B, Grifoni S, et al. Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations. Acta Neuropathol. 2011;121:611-22 pubmed 出版商
|
| Higashi S, Tsuchiya Y, Araki T, Wada K, Kabuta T. TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase. Neurochem Int. 2010;57:906-13 pubmed 出版商
|
| Wang D, Dayton R, Henning P, Cain C, Zhao L, Schrott L, et al. Expansive gene transfer in the rat CNS rapidly produces amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed. Mol Ther. 2010;18:2064-74 pubmed 出版商
|
| Hoftberger R, Fink S, Aboul Enein F, Botond G, Olah J, Berki T, et al. Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis. Glia. 2010;58:1847-57 pubmed 出版商
|
| Xu Y, Gendron T, Zhang Y, Lin W, D Alton S, Sheng H, et al. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci. 2010;30:10851-9 pubmed 出版商
|
| Ling S, Albuquerque C, Han J, Lagier Tourenne C, Tokunaga S, Zhou H, et al. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc Natl Acad Sci U S A. 2010;107:13318-23 pubmed 出版商
|
| Jansen C, Head M, van Gool W, Baas F, Yull H, Ironside J, et al. The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype. J Neurol Neurosurg Psychiatry. 2010;81:1052-5 pubmed 出版商
|
| Ash P, Zhang Y, Roberts C, Saldi T, Hutter H, Buratti E, et al. Neurotoxic effects of TDP-43 overexpression in C. elegans. Hum Mol Genet. 2010;19:3206-18 pubmed 出版商
|
| Maruyama H, Morino H, Ito H, Izumi Y, Kato H, Watanabe Y, et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 2010;465:223-6 pubmed 出版商
|
| Braak H, Ludolph A, Thal D, Del Tredici K. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord. Acta Neuropathol. 2010;120:67-74 pubmed 出版商
|
| Ilieva E, Naudi A, Kichev A, Ferrer I, Pamplona R, Portero Otin M. Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease. Free Radic Biol Med. 2010;48:1302-10 pubmed 出版商
|
| Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, Cuijt I, et al. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A. 2010;107:3858-63 pubmed 出版商
|
| Zhang H, Tanji K, Yoshida H, Hayakari M, Shibata T, Mori F, et al. Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). Exp Neurol. 2010;222:296-303 pubmed 出版商
|
| Nishimoto Y, Ito D, Yagi T, Nihei Y, Tsunoda Y, Suzuki N. Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. J Biol Chem. 2010;285:608-19 pubmed 出版商
|
| Foulds P, Davidson Y, Mishra M, Hobson D, Humphreys K, Taylor M, et al. Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathol. 2009;118:647-58 pubmed 出版商
|
| Velakoulis D, Walterfang M, Mocellin R, Pantelis C, Dean B, McLean C. Abnormal hippocampal distribution of TDP-43 in patients with-late onset psychosis. Aust N Z J Psychiatry. 2009;43:739-45 pubmed 出版商
|
| Moisse K, Mepham J, Volkening K, Welch I, Hill T, Strong M. Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL-/- mice: support for a role for TDP-43 in the physiological response to neuronal injury. Brain Res. 2009;1296:176-86 pubmed 出版商
|
| Velakoulis D, Walterfang M, Mocellin R, Pantelis C, McLean C. Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series and review of cases. Br J Psychiatry. 2009;194:298-305 pubmed 出版商
|
| Humayun S, Gohar M, Volkening K, Moisse K, Leystra Lantz C, Mepham J, et al. The complement factor C5a receptor is upregulated in NFL-/- mouse motor neurons. J Neuroimmunol. 2009;210:52-62 pubmed 出版商
|
| Gitcho M, Strider J, Carter D, Taylor Reinwald L, Forman M, Goate A, et al. VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death. J Biol Chem. 2009;284:12384-98 pubmed 出版商
|
| Olive M, Janué A, Moreno D, Gamez J, Torrejón Escribano B, Ferrer I. TAR DNA-Binding protein 43 accumulation in protein aggregate myopathies. J Neuropathol Exp Neurol. 2009;68:262-73 pubmed 出版商
|
| Rollinson S, Rizzu P, Sikkink S, Baker M, Halliwell N, Snowden J, et al. Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiol Aging. 2009;30:656-65 pubmed 出版商
|
| Igaz L, Kwong L, Chen Plotkin A, Winton M, Unger T, Xu Y, et al. Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. J Biol Chem. 2009;284:8516-24 pubmed 出版商
|
| Clarimon J, Molina Porcel L, Gomez Isla T, Blesa R, Guardia Laguarta C, Gonzalez Neira A, et al. Early-onset familial lewy body dementia with extensive tauopathy: a clinical, genetic, and neuropathological study. J Neuropathol Exp Neurol. 2009;68:73-82 pubmed 出版商
|
| Moisse K, Volkening K, Leystra Lantz C, Welch I, Hill T, Strong M. Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury. Brain Res. 2009;1249:202-11 pubmed 出版商
|
| Schwab C, Arai T, Hasegawa M, Yu S, McGeer P. Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease. J Neuropathol Exp Neurol. 2008;67:1159-65 pubmed 出版商
|
| Steinacker P, Hendrich C, Sperfeld A, Jesse S, von Arnim C, Lehnert S, et al. TDP-43 in cerebrospinal fluid of patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Arch Neurol. 2008;65:1481-7 pubmed 出版商
|
| Seppänen A, Pikkarainen M, Hartikainen P, Hofmann S, Majamaa K, Alafuzoff I. Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease. Brain Res. 2009;1247:171-7 pubmed 出版商
|
| Kasai T, Tokuda T, Ishigami N, Sasayama H, Foulds P, Mitchell D, et al. Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol. 2009;117:55-62 pubmed 出版商
|
| Nishihira Y, Tan C, Hoshi Y, Iwanaga K, Yamada M, Kawachi I, et al. Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology. Acta Neuropathol. 2009;117:45-53 pubmed 出版商
|
| Skoglund L, Brundin R, Olofsson T, Kalimo H, Ingvast S, Blom E, et al. Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation. Neurogenetics. 2009;10:27-34 pubmed 出版商
|
| Miklossy J, Steele J, Yu S, McCall S, Sandberg G, McGeer E, et al. Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC). Acta Neuropathol. 2008;116:625-37 pubmed 出版商
|
| Weihl C, Temiz P, Miller S, Watts G, Smith C, Forman M, et al. TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. J Neurol Neurosurg Psychiatry. 2008;79:1186-9 pubmed 出版商
|
| Mori F, Tanji K, Zhang H, Nishihira Y, Tan C, Takahashi H, et al. Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008;116:193-203 pubmed 出版商
|
| Sleegers K, Kumar Singh S, Cruts M, Van Broeckhoven C. Molecular pathogenesis of frontotemporal lobar degeneration: basic science seminar in neurology. Arch Neurol. 2008;65:700-4 pubmed 出版商
|
| Johnson B, McCaffery J, Lindquist S, Gitler A. A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proc Natl Acad Sci U S A. 2008;105:6439-44 pubmed 出版商
|
| Winton M, Igaz L, Wong M, Kwong L, Trojanowski J, Lee V. Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J Biol Chem. 2008;283:13302-9 pubmed 出版商
|
| Zhang H, Tanji K, Mori F, Wakabayashi K. Epitope mapping of 2E2-D3, a monoclonal antibody directed against human TDP-43. Neurosci Lett. 2008;434:170-4 pubmed 出版商
|
| Beck J, Rohrer J, Campbell T, Isaacs A, Morrison K, Goodall E, et al. A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. Brain. 2008;131:706-20 pubmed 出版商
|
| Sanelli T, Xiao S, Horne P, Bilbao J, Zinman L, Robertson J. Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol. 2007;66:1147-53 pubmed
|
| Kovacs G, Pittman A, Revesz T, Luk C, Lees A, Kiss E, et al. MAPT S305I mutation: implications for argyrophilic grain disease. Acta Neuropathol. 2008;116:103-18 pubmed
|
| Shankaran S, Capell A, Hruscha A, Fellerer K, Neumann M, Schmid B, et al. Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. J Biol Chem. 2008;283:1744-53 pubmed
|
| Zhang H, Tan C, Mori F, Tanji K, Kakita A, Takahashi H, et al. TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008;115:115-22 pubmed
|
| Amador Ortiz C, Lin W, Ahmed Z, Personett D, Davies P, Duara R, et al. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol. 2007;61:435-45 pubmed
|
| Mackenzie I, Bigio E, Ince P, Geser F, Neumann M, Cairns N, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol. 2007;61:427-34 pubmed
|
| Hasegawa M, Arai T, Akiyama H, Nonaka T, Mori H, Hashimoto T, et al. TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. Brain. 2007;130:1386-94 pubmed
|
| Neumann M, Kwong L, Truax A, Vanmassenhove B, Kretzschmar H, Van Deerlin V, et al. TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J Neuropathol Exp Neurol. 2007;66:177-83 pubmed
|
| Tan C, Eguchi H, Tagawa A, Onodera O, Iwasaki T, Tsujino A, et al. TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation. Acta Neuropathol. 2007;113:535-42 pubmed
|
| Neumann M, Mackenzie I, Cairns N, Boyer P, Markesbery W, Smith C, et al. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. J Neuropathol Exp Neurol. 2007;66:152-7 pubmed
|
| Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2006;351:602-11 pubmed
|