产品简要
公司名称 :
亚诺法生技股份有限公司
产品类型 :
抗体
产品名称 :
EIF2C2单克隆抗体(M01), 克隆2E12-1C9
目录 :
H00027161-M01
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2E12-1C9
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s3a
Xiao R, Chen J, Liang Z, Luo D, Chen G, Lu Z, et al. Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell. 2019;178:107-121.e18 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1c
  • 免疫印迹; 人类; 图 s12b
Huang J, Ku W, Chen Y, Chang Y, Chu C. Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6. Sci Rep. 2017;7:42853 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 s1
Slezak Prochazka I, Kluiver J, de Jong D, Smigielska Czepiel K, Kortman G, Winkle M, et al. Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma. Oncotarget. 2016;7:2391-400 pubmed 出版商
  • 免疫沉淀; 小鼠
Le Guillou S, Marthey S, Laloé D, Laubier J, Mobuchon L, Leroux C, et al. Characterisation and comparison of lactating mouse and bovine mammary gland miRNomes. PLoS ONE. 2014;9:e91938 pubmed 出版商
Li H, Zhan J, Zhao Y, Fan J, Yuan S, Yin Z, et al. Identification of ncRNA-Mediated Functions of Nucleus-Localized miR-320 in Cardiomyocytes. Mol Ther Nucleic Acids. 2019;19:132-143 pubmed 出版商
Curtale G, Renzi T, Mirolo M, Drufuca L, Albanese M, De Luca M, et al. Multi-Step Regulation of the TLR4 Pathway by the miR-125a~99b~let-7e Cluster. Front Immunol. 2018;9:2037 pubmed 出版商
Han H, Choi B, Kim J, Kang G, Koo S. Hepatic Crtc2 controls whole body energy metabolism via a miR-34a-Fgf21 axis. Nat Commun. 2017;8:1878 pubmed 出版商
Llobet Navas D, Rodríguez Barrueco R, de la Iglesia Vicente J, Olivan M, Castro V, Saucedo Cuevas L, et al. The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells. Mol Cell Biol. 2014;34:4216-31 pubmed 出版商
Pai B, Siripornmongcolchai T, Berentsen B, Pakzad A, Vieuille C, Pallesen S, et al. NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo. Front Cell Neurosci. 2014;7:285 pubmed 出版商
Wei N, Zhang L, Huang H, Chen Y, Zheng J, Zhou X, et al. siRNA has greatly elevated mismatch tolerance at 3'-UTR sites. PLoS ONE. 2012;7:e49309 pubmed 出版商
Nazari Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen R, et al. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest. 2012;122:4190-202 pubmed 出版商
Tiedje C, Ronkina N, Tehrani M, Dhamija S, Laass K, Holtmann H, et al. The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation. PLoS Genet. 2012;8:e1002977 pubmed 出版商
Reed J, Molter B, Geary C, McNevin J, McElrath J, Giri S, et al. HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly. J Cell Biol. 2012;198:439-56 pubmed 出版商
Kluiver J, Slezak Prochazka I, Smigielska Czepiel K, Halsema N, Kroesen B, van den Berg A. Generation of miRNA sponge constructs. Methods. 2012;58:113-7 pubmed 出版商
Dolezalova D, Mraz M, Bárta T, Plevova K, Vinarsky V, Holubcová Z, et al. MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. Stem Cells. 2012;30:1362-72 pubmed 出版商
Bañez Coronel M, Porta S, Kagerbauer B, Mateu Huertas E, Pantano L, Ferrer I, et al. A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity. PLoS Genet. 2012;8:e1002481 pubmed 出版商
He M, Liu Y, Wang X, Zhang M, Hannon G, Huang Z. Cell-type-based analysis of microRNA profiles in the mouse brain. Neuron. 2012;73:35-48 pubmed 出版商
Chiang K, Sung T, Rice A. Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. J Virol. 2012;86:3244-52 pubmed 出版商
Martinez Sanchez A, Dudek K, Murphy C. Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145). J Biol Chem. 2012;287:916-24 pubmed 出版商
Cook D, Sánchez Carbente M, Lachance C, Radzioch D, Tremblay S, Khandjian E, et al. Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus. PLoS ONE. 2011;6:e26120 pubmed 出版商
Turchinovich A, Weiz L, Langheinz A, Burwinkel B. Characterization of extracellular circulating microRNA. Nucleic Acids Res. 2011;39:7223-33 pubmed 出版商
Lund E, Sheets M, Imboden S, Dahlberg J. Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis. Genes Dev. 2011;25:1121-31 pubmed 出版商
Glorian V, Maillot G, Polès S, Iacovoni J, Favre G, Vagner S. HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis. Cell Death Differ. 2011;18:1692-701 pubmed 出版商
Rawlings R, Krishnan V, Walter N. Viral RNAi suppressor reversibly binds siRNA to outcompete Dicer and RISC via multiple turnover. J Mol Biol. 2011;408:262-76 pubmed 出版商
Wang Y, Lacroix G, Haines J, Doukhanine E, Almazan G, Richard S. The QKI-6 RNA binding protein localizes with the MBP mRNAs in stress granules of glial cells. PLoS ONE. 2010;5: pubmed 出版商
Cheloufi S, Dos Santos C, Chong M, Hannon G. A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature. 2010;465:584-9 pubmed 出版商
Flemr M, Ma J, Schultz R, Svoboda P. P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes. Biol Reprod. 2010;82:1008-17 pubmed 出版商
Lin J, Tarn W. RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell differentiation. J Biol Chem. 2009;284:34658-65 pubmed 出版商
Tan L, Seinen E, Duns G, de Jong D, Sibon O, Poppema S, et al. A high throughput experimental approach to identify miRNA targets in human cells. Nucleic Acids Res. 2009;37:e137 pubmed 出版商
Landry P, Plante I, Ouellet D, Perron M, Rousseau G, Provost P. Existence of a microRNA pathway in anucleate platelets. Nat Struct Mol Biol. 2009;16:961-6 pubmed 出版商
Zeitelhofer M, Karra D, Macchi P, Tolino M, Thomas S, Schwarz M, et al. Dynamic interaction between P-bodies and transport ribonucleoprotein particles in dendrites of mature hippocampal neurons. J Neurosci. 2008;28:7555-62 pubmed 出版商
Zeng Y, Sankala H, Zhang X, Graves P. Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. Biochem J. 2008;413:429-36 pubmed 出版商
Alisch R, Jin P, Epstein M, Caspary T, Warren S. Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation. PLoS Genet. 2007;3:e227 pubmed 出版商
Vickers T, Lima W, Nichols J, Crooke S. Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells. Nucleic Acids Res. 2007;35:6598-610 pubmed
Krol J, Fiszer A, Mykowska A, Sobczak K, de Mezer M, Krzyzosiak W. Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets. Mol Cell. 2007;25:575-86 pubmed
产品信息
目录号码 :
H00027161-M01
产品名称 :
EIF2C2单克隆抗体(M01), 克隆2E12-1C9
产品描述 :
小鼠单克隆抗体抗a全长重组EIF2C2
克隆名称 :
2E12-1C9
抗体亚型 :
IgG1 Kappa
基因名称 :
EIF2C2
基因别名 :
AGO2 MGC3183 Q10
基因描述 :
eukaryotic translation initiation factor 2C, 2
GenBank登录号 :
BC007633.1
免疫原 :
EIF2C2 (AAH07633.1, 483 a.a. ~ 859 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
免疫原序列蛋白序列 :
MPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVI
LPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTL
SNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVT
HPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEI
IQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQ
QVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLF
CTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAG
IQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCT
RSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQ
SNGRDHQALAKAVQVHQDTLRTMYFA
蛋白登录号 :
AAH07633.1
储存缓冲液 :
在1x PBS, pH值7.4
储存说明 :
储存在-20℃或更低。分装以避免反复冻融
质量控制试验 :
抗体能识别重组蛋白
类型克隆性 :
抗体
宿主物种 :
小鼠
抗原物种靶物种 :
人类
物种活性交叉活性 :
人类
应用 :
WB-Ce,WB-Tr,S-ELISA,RNAi-Ab,ELISA,WB-Re,IF,IHC-P
规格 :
100微克
开始日期 :
12/4/07
更新日期 :
1/21/20 11:48
公司信息
亚诺法生技股份有限公司
台湾台北市內湖區洲子街108號9樓
sales@abnova.com
https://www.abnova.com
886-2-87511888