产品简要
公司名称 :
Absolute Antibody
产品类型 :
抗体
产品名称 :
Anti-Fas [R-125224]
目录 :
Ab00802-21.0
规格 :
50微克
价格 :
500美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
R-125224
反应物种 :
人类
应用 :
酶联免疫吸附测定, 流式细胞仪
更多信息或购买 :
产品信息
产品名称 :
Anti-Fas [R-125224]
目录号 :
Ab00802-21.0
靶标 :
肿瘤坏死因子受体超家族成员6
抗体物种 :
小鼠
抗体亚型 :
IgM
LCFormat :
kappa
靶标同义词 :
CD95; h-HFE7A; Tumor necrosis factor receptor superfamily member 6; CD-95; Apo-1; Apo 1; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor
Display Amount :
50微克
PriceGBP :
385
PriceEUR :
425
PriceUSD :
500美元
产品类型 :
一抗
克隆性 :
单克隆
ApplicationCodesClone :
激活的;图像;酶联免疫吸附测定;FC
免疫原 :
R-125224 is generated by the humanization of the murine HFE7A anti-Fas antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas or the L5178YA1 cell line expressing murine Fas, but not to the parental WR19L or L5178Y cells.
MarketingCategories :
RA; oncology; cancer; biosimilar
Available Custom Conjugation Options :
AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
UniprotAccessionNo :
P25445
产品描述 :
This is a recombinant monoclonal antibody.
更多信息或购买 :
公司信息
Absolute Antibody
Wilton Centre
Redcar
Cleveland
TS10 4RF
info@absoluteantibody.com
https://absoluteantibody.com/
1-617-377-4057
公司总部: United Kingdom