产品简要
公司名称 :
Active Motif
其他品牌 :
Geneka Biotechnology
产品类型 :
抗体
产品名称 :
RNA pol II antibody (mAb)
目录 :
39097
规格 :
200微升
价格 :
350美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, , 秀丽隐杆线虫
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:200; 图 6i
Pan H, Jiang N, Sun S, Jiang H, Xu J, Jiang X, et al. UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I. Cell Death Dis. 2020;11:142 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3e
Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 4b
Garcia Cuellar M, Büttner C, Bartenhagen C, Dugas M, Slany R. Leukemogenic MLL-ENL Fusions Induce Alternative Chromatin States to Drive a Functionally Dichotomous Group of Target Genes. Cell Rep. 2016;15:310-22 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 s3
Reeder J, Kwak Y, McNamara R, Forst C, D Orso I. HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells. elife. 2015;4: pubmed 出版商
  • 染色质免疫沉淀 ; 人类
He X, Zhang P. Serine/arginine-rich splicing factor 3 (SRSF3) regulates homologous recombination-mediated DNA repair. Mol Cancer. 2015;14:158 pubmed 出版商
  • 染色质免疫沉淀 ; 大鼠
Winston J, Li Q, Sarna S. Chronic prenatal stress epigenetically modifies spinal cord BDNF expression to induce sex-specific visceral hypersensitivity in offspring. Neurogastroenterol Motil. 2014;26:715-30 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Li J, Kannan M, Trivett A, Liao H, Wu X, Akagi K, et al. An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition. Nucleic Acids Res. 2014;42:4546-62 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 1:500
Pang C, Toh S, He P, Teissier S, Ben Khalifa Y, Xue Y, et al. A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S- and M-phase genes. (129 c). Oncogene. 2014;33:4039-49 pubmed 出版商
  • 染色质免疫沉淀 ; 鸡
Ellis H, Shioda K, Rosenthal N, Coser K, Shioda T. Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to estrogen-induced phenotypic sex conversion. Biol Reprod. 2012;87:23, 1-12 pubmed 出版商
  • 免疫细胞化学; 仓鼠
  • 免疫印迹; 仓鼠
Akhrymuk I, Kulemzin S, Frolova E. Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II. J Virol. 2012;86:7180-91 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Weishaupt H, Attema J. A Method to Study the Epigenetic Chromatin States of Rare Hematopoietic Stem and Progenitor Cells; MiniChIP-Chip. Biol Proced Online. 2010;12:1-17 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 3 ug
Udelhoven M, Pasieka M, Leeser U, Krone W, Schubert M. Neuronal insulin receptor substrate 2 (IRS2) expression is regulated by ZBP89 and SP1 binding to the IRS2 promoter. J Endocrinol. 2010;204:199-208 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 3 ug
Udelhoven M, Leeser U, Freude S, Hettich M, Laudes M, Schnitker J, et al. Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells. J Mol Endocrinol. 2010;44:99-113 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Leng J, Butcher B, Egan C, Abi Abdallah D, Denkers E. Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation. J Immunol. 2009;182:489-97 pubmed
Stratton M, Bagchi R, Felisbino M, Hirsch R, Smith H, Riching A, et al. Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation. Circ Res. 2019;125:662-677 pubmed 出版商
Miao H, Wang L, Zhan H, Dai J, Chang Y, Wu F, et al. A long noncoding RNA distributed in both nucleus and cytoplasm operates in the PYCARD-regulated apoptosis by coordinating the epigenetic and translational regulation. PLoS Genet. 2019;15:e1008144 pubmed 出版商
Ogiwara H, Takahashi K, Sasaki M, Kuroda T, Yoshida H, Watanabe R, et al. Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers. Cancer Cell. 2019;35:177-190.e8 pubmed 出版商
Holmes B, Benavides Serrato A, Freeman R, Landon K, Bashir T, Nishimura R, et al. mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma. Oncogene. 2017;: pubmed 出版商
Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald K. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. J Immunol. 2017;199:3249-3260 pubmed 出版商
Schmidt N, Irle I, Ripkens K, Lux V, Nelles J, Johannes C, et al. Epigenetic silencing of serine protease HTRA1 drives polyploidy. BMC Cancer. 2016;16:399 pubmed 出版商
Plummer S, Dan D, Quinney J, Hallmark N, Phillips R, Millar M, et al. Identification of transcription factors and coactivators affected by dibutylphthalate interactions in fetal rat testes. Toxicol Sci. 2013;132:443-57 pubmed 出版商
Woellmer A, Arteaga Salas J, Hammerschmidt W. BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression. PLoS Pathog. 2012;8:e1002902 pubmed 出版商
Song R, Ro S, Michaels J, Park C, McCarrey J, Yan W. Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nat Genet. 2009;41:488-93 pubmed 出版商
产品信息
目录代码 :
39097
产品名称 :
RNA pol II antibody (mAb)
宿主物种 :
小鼠
克隆性 :
单克隆
规格 :
200微升
标价 :
350美元
克隆 :
4H8
抗体亚型 :
IgG
交叉活性 :
Budding Yeast, C. elegans, Human, Mouse, Rat
背景 :
RNA pol II (RNA polymerase II) is responsible for synthesizing messenger RNA in eukaryotes. RNA pol II contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, RNA pol II, in combination with several other polymerase subunits, form the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
免疫原 :
This RNA pol II antibody was raised against a synthetic peptide YSPTSpPS corresponding to human RNA pol II. It recognizes both the phosphorylated and unphosphorylated forms of the largest subunit of RNA pol II.
用途 :
ChIP, 酶联免疫吸附测定, IF, 免疫沉淀, 免疫印迹
储存 :
Antibodies in solution can be stored at -800C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
更多信息或购买 :
公司信息
Active Motif
787 Kangqiao Road,Building 10, Suite 202,Pudong District,Shanghai, China
techchina@activemotif.com
http://www.activemotif.com
86-21-20926090 400-018-8123
公司总部: 美国