产品简要
公司名称 :
Active Motif
其他品牌 :
Geneka Biotechnology
产品类型 :
抗体
产品名称 :
DNMT3A抗体(单克隆抗体)
目录 :
39206
规格 :
100微克
价格 :
350美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
64B1446
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
文章摘录数: 2
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产品信息
目录代码 :
39206
产品名称 :
DNMT3A抗体(单克隆抗体)
宿主物种 :
小鼠
克隆性 :
单克隆
规格 :
100微克
标价 :
350美元
克隆 :
64B1446
抗体亚型 :
IgG
交叉活性 :
人类, 小鼠
背景 :
DNMT3A M-bM-^@M-^S DNA methyltransferase proteins such as DNMT3A (or DNMT 3A) are involved in DNA methylation, in which a methyl group is added to a cytosine residue on DNA, commonly at the C5 position of a CpG dinucleotide. DNMT3A has been shown to be important in the regulation of specific patterns of DNA methylation. Methylation of mammalian DNA has long been recognized to play a major role in a number of cellular functions such as embryonic development, genetic imprinting, X chromosome inactivation and control of gene expression. DNA methylation is generally associated with transcriptional repression.Three families of DNMTs have been identified: DNMT1, DNMT2 and DNMT3. The DNMT3 family, containing two active methyltransferases, DNMT3A & DNMT3B, and one DNMT3-Like protein (DNMT3L), establishes the initial CpG methylation pattern de novo and shows the same propensity for methylating unmethylated duplex DNA as for hemi-methylated DNA. DNMT3A and DNMT3B are encoded by two distinct genes and are strongly expressed in embryonic stem cells. DNMT3A is ubiquitous in mammalian cells.
免疫原 :
This DNMT3A antibody was raised against a full-length protein corresponding to mouse DNMT3A.
用途 :
ChIP, IF, 免疫组化, 免疫沉淀, 免疫印迹
储存 :
Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
更多信息或购买 :
公司信息
Active Motif
787 Kangqiao Road，Building 10, Suite 202，Pudong District，Shanghai, China
techchina@activemotif.com
http://www.activemotif.com86-21-20926090 400-018-8123
公司总部: 美国