Geneka Biotechnology

抗体

组蛋白H3K14me2抗体(多克隆抗体)

39349

200微升

350美元

多克隆

domestic rabbit

未共轭

组蛋白H3K14me2抗体(多克隆抗体)

兔

多克隆

Methylated

200微升

350美元

血清

Human, Other (Wide Range)

Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression.The methylation of histones can occur on two different residues: arginine or lysine. Histone methylation can be associated with transcriptional activation or repression, depending on the methylated residue.

这组蛋白H3二甲基Lys14通过免疫制备抗体a肽含二甲基赖氨酸14人的组蛋白H3

DB, 免疫印迹

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.