Geneka Biotechnology

抗体

PARP-1 C末端抗体(多克隆抗体)

39561

200微升

350美元

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化, 免疫沉淀, 染色质免疫沉淀

PARP-1 C末端抗体(多克隆抗体)

兔

多克隆

200微升

350美元

血清

人类

PARP-1 C-terminal (ADPRT) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation and tumor transformation. It also plays a role in the regulation of the molecular events involved in the recovery of cells from DNA damage. Cleavage of PARP-1 (ADPRT) occurs following caspase activation during apoptosis.For additional information on PARP-1, please see the review article PARP-1: An Abundant and Ubiquitous Protein with Roles in Many Cellular Processes in the Targets & Applications section or our website.

This PARP-1 C-terminal antibody was raised against a His-tagged fusion protein corresponding to the C-terminal half of human PARP-1 was used to generate this PARP-1 antibody.

ChIP, 免疫组化, 免疫沉淀, 免疫印迹

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

References: This antibody has been used in the following references: Kim MY et al. (2004) Cell 119: 803-814.Krishnakumar R et al. (2008) Science 319: 819-821.