Geneka Biotechnology

抗体

AIB1/SRC-3抗体(多克隆抗体)

39797

100微升

350美元

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫沉淀, 染色质免疫沉淀

AIB1/SRC-3抗体(多克隆抗体)

兔

多克隆

100微升

350美元

IgG

人类

AIB1 (Amplified in Breast Cancer 1, Steroid Receptor Coactivator-3, Nuclear Receptor Coactivator 3, SRC-3, NCOA3) is a chromatin-associated protein that interacts with nuclear hormone receptors to modify their activity as transcriptional activators. AIB1 has histone acetyltransferase (HAT) activity and recruits p300/CBP-associated factor (PCAF) and CREB binding protein (CBP) as part of a multisubunit co-activator complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. It is Involved in the coactivation of different nuclear receptors, such as GR, ER, RARs, RXRs, TRs, VDR and PPARs. It is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFM-NM-:B1 protein.

This AIB1 antibody was raised against a peptide derived from human AIB1/SRC-3.

ChIP, 免疫沉淀, 免疫印迹

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.