产品简要
公司名称 :
Active Motif
其他品牌 :
Geneka Biotechnology
产品类型 :
抗体
产品名称 :
Nucleophosmin antibody (pAb)
目录 :
39849
规格 :
100微升
价格 :
350美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录代码 :
39849
产品名称 :
Nucleophosmin antibody (pAb)
宿主物种 :
克隆性 :
多克隆
规格 :
100微升
标价 :
350美元
抗体亚型 :
血清
交叉活性 :
人类
背景 :
Nucleophosmin (NPM, NPM1, Nucleolar phosphoprotein B23) is a highly phosphorylated nucleolar protein involved in ribosome biogenesis, maintenance of genome stability, is directly implicated in cancer pathogenesis and serves as a histone chaperone. Nucleophosmin is closely related to Nucleoplasmin and shuttles back and forth between the nucleolus and the nucleoplasm. Chromosomal aberrations involving Nucleophosmin were found in patients with non-Hodgkin lymphoma, acute promyelocytic leukemia, myelodysplastic syndrome, and acute myelogenous leukemia. Nucleophosmin has been shown to interact with Nucleolin. AKT1, BRCA1 and BARD1. Mice deficient for Nucleophosmin have severe defects in genome stability due to unrestricted centrosome duplication. Heterozygous Nucleophosmin mutant mice show signs of myelodysplastic syndrome.
免疫原 :
This Nucleophosmin antibody was raised against a peptide within the C-terminal region of human nucleophosmin.
用途 :
免疫印迹
储存 :
Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
更多信息或购买 :
公司信息
Active Motif
787 Kangqiao Road,Building 10, Suite 202,Pudong District,Shanghai, China
techchina@activemotif.com
www.activemotif.com
86-21-20926090 400-018-8123
公司总部: 美国