免疫印迹, 免疫细胞化学, 免疫沉淀
Argonaute 2 (Ago2, aka EIF2C2) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Binding of RISC can inhibit mRNA translation and results in the degradation of the mRNA through the action of Ago2-mediated target cleavage.
This Ago2 antibody was raised against a recombinant protein corresponding to amino acids 1-148 of human Ago2.
IF, 免疫沉淀, 免疫印迹
Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
References: This antibody has been used as described in the following references: IF: Azuma AM et al. (2010) PNAS 105: 7964-7969 IP: Azuma AM et al. (2010) PNAS 105: 7964-7969 WB: Azuma AM et al. (2010) PNAS 105: 7964-7969