Geneka Biotechnology

抗体

CDT1抗体(单克隆抗体)

61039

100微克

350美元

单克隆

仓鼠

未共轭

免疫印迹, 免疫组化, 免疫沉淀

CDT1抗体(单克隆抗体)

仓鼠

单克隆

100微克

350美元

IgG

人类

CDT1 (chromatin licensing and DNA replication factor 1) is a key licensing factor which functions to allow DNA replication. It is recruited (along with CDC6) by the ORC (Origin Recognition Complex) to sites of DNA replication and helps form the pre-replicative complex (pre-RC). Its activity during the cell cycle is regulated by its association with the Geminin protein geminin, which both inhibits CDT1 activity during S phase in order to prevent unregulated DNA replication and also to inhibit CDT1 proteolysis.

This CDT1 antibody was raised against a recombinant protein corresponding to amino acids 177-557 of mouse CDT1.

免疫组化, 免疫沉淀, 免疫印迹

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

References: This antibody has been used in the following references: WB: Arentson E et al. (2002) Oncogene 21: 1150-1158.