产品简要
公司名称 :
Active Motif
其他品牌 :
Geneka Biotechnology
产品类型 :
抗体
产品名称 :
SIRT2抗体(多克隆抗体)
目录 :
61043
规格 :
100微升
价格 :
350美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
产品信息
目录代码 :
61043
产品名称 :
SIRT2抗体(多克隆抗体)
宿主物种 :
克隆性 :
多克隆
规格 :
100微升
标价 :
350美元
抗体亚型 :
血清
交叉活性 :
人类
背景 :
SIRT2 is a member of the SIR2 / Sirtuin family of NAD-dependant deacetylase enzymes. It has multiple targets for deacetylation, including tubulin, P53, HOXA10, FOXO3A, P300, FOXO1. SIRT2 suppresses adipogenesis by deacetylating FOXO1, promoting the binding of FOXO1 to PPARM-NM-3 and subsequent repression of PPARM-NM-3 mediated transcriptional activation. Similar to SIRT1, SIRT2 also deacetylates H4AcK16 similar to SIRT1, SIRT2 deacetylates histone H4 at lysine 16. SIRT2 is present in the cytoplasm during most of the cell cycle except in the G2/M transition and in mitosis, where it is found in the nucleus and in contact with chromatin and required for exit from mitosis.
免疫原 :
This SIRT2 antibody was raised against a peptide within the C-terminal region of human SIRT2 protein.
用途 :
IF, 免疫沉淀, 免疫印迹
储存 :
Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
产品引用 :
References: This antibody has been used in the following references: IF: Dryden SC et al. (2003) Molec Cell Biol 23: 3173M-bM-^@M-^S3185.WB: Dryden SC et al. (2003) Molec Cell Biol 23: 3173M-bM-^@M-^S3185.
更多信息或购买 :
公司信息
Active Motif
787 Kangqiao Road,Building 10, Suite 202,Pudong District,Shanghai, China
techchina@activemotif.com
http://www.activemotif.com
86-21-20926090 400-018-8123
公司总部: 美国