Geneka Biotechnology

抗体

HIF-1甲抗体(单克隆抗体)

61275

100微克

350美元

单克隆

小鼠

未共轭

ESEE122

人类, 小鼠, 大鼠, 牛

免疫印迹, 免疫组化

HIF-1甲抗体(单克隆抗体)

小鼠

单克隆

100微克

350美元

ESEE122

IgG1

牛, 人类, 小鼠, 大鼠

HIF-1 (hypoxia inducible factor 1, alpha subunit, MOP1, PASD8, bHLHe78, PAS domain-containing protein 8) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

This HIF-1 alpha antibody was raised against a partial protein containing amino acid residues 329-530 of human HIF-1 alpha.

免疫组化

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

References: The use of this antibody is described in the following references:IHC: Yoshimura H et al. (2004) Clinical Cancer Res 10:8554-8560.Tan E.Y. et al. (2007) Breast Cancer Res 9(6):R89.Beasley N.J.P. (2008) Cancer Res 62:2493-2497.