Geneka Biotechnology

抗体

FOXL2抗体(多克隆抗体)

61283

100微升

350美元

多克隆

domestic rabbit

未共轭

FOXL2抗体(多克隆抗体)

兔

多克隆

100微升

350美元

IgG

人类

FOXL2 (forkhead box L2, BPES, PFRK, POF3, BPES1, PINTO) is a transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

This antibody was raised against a peptide within the N-terminal region of human FOXL2.

免疫印迹

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.