产品简要
公司名称 :
Addgene
产品类型 :
cDNA
产品名称 :
HER2 WT
目录 :
16257
更多信息或购买 :
文章摘录数: 30
参考文献
Sailer C, Hong Y, Dahal A, Ryan A, Mir S, Gerber S, et al. PD-1Hi CAR-T cells provide superior protection against solid tumors. Front Immunol. 2023;14:1187850 pubmed 出版商
Corogeanu D, Zaki K, Beavil A, Arnold J, Diebold S. Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue. PLoS ONE. 2023;18:e0282831 pubmed 出版商
Kollara A, Burt B, Ringuette M, Brown T. The adaptor protein VEPH1 interacts with the kinase domain of ERBB2 and impacts EGF signaling in ovarian cancer cells. Cell Signal. 2023;106:110634 pubmed 出版商
Yu B, Shi Q, Belk J, Yost K, Parker K, Li R, et al. Engineered cell entry links receptor biology with single-cell genomics. Cell. 2022;185:4904-4920.e22 pubmed 出版商
Godfrey J, Hejazi D, Du X, Wei C, Rao E, Gomez C. HER2 c-Terminal Fragments Are Expressed via Internal Translation of the HER2 mRNA. Int J Mol Sci. 2022;23: pubmed 出版商
Hart V, Silipo M, Satam S, Gautrey H, Kirby J, Tyson Capper A. HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer. J Cancer Res Clin Oncol. 2021;: pubmed 出版商
Kundumani Sridharan V, Subramani J, Owens C, Das K. Nrg1β Released in Remote Ischemic Preconditioning Improves Myocardial Perfusion and Decreases Ischemia/Reperfusion Injury via ErbB2-Mediated Rescue of Endothelial Nitric Oxide Synthase and Abrogation of Trx2 Autophagy. Arterioscler Thromb Vasc Biol. 2021;41:2293-2314 pubmed 出版商
Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed 出版商
Yang Y, Leonard M, Luo Z, Yeo S, Bick G, Hao M, et al. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell Rep. 2021;34:108822 pubmed 出版商
Yoshioka H, Ramakrishnan S, Shim J, Suzuki A, Iwata J. Excessive All-Trans Retinoic Acid Inhibits Cell Proliferation Through Upregulated MicroRNA-4680-3p in Cultured Human Palate Cells. Front Cell Dev Biol. 2021;9:618876 pubmed 出版商
Jeon I, Lee J, Shin K, Kang T, Park M, Seo H, et al. Enhanced Immunogenicity of Engineered HER2 Antigens Potentiates Antitumor Immune Responses. Vaccines (Basel). 2020;8: pubmed 出版商
Jung D, Bae Y, Kim J, Shin Y, Jeung H. HER2 Regulates Cancer Stem Cell Activities via the Wnt Signaling Pathway in Gastric Cancer Cells. Oncology. 2019;97:311-318 pubmed 出版商
Wang W, Gao Y, Hai J, Yang J, Duan S. HER2 decreases drug sensitivity of ovarian cancer cells via inducing stem cell-like property in an NFκB-dependent way. Biosci Rep. 2019;39: pubmed 出版商
Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, et al. Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells. Breast Cancer Res. 2018;20:112 pubmed 出版商
Kurmi K, Hitosugi S, Yu J, Boakye Agyeman F, Wiese E, Larson T, et al. Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway. Cell Metab. 2018;28:833-847.e8 pubmed 出版商
Yin J, Albers A, Smith T, Riddell G, Richards J. Differential regulation of human monocytes and NK cells by antibody-opsonized tumors. Cancer Immunol Immunother. 2018;67:1239-1250 pubmed 出版商
Carpenter R, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, et al. Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth. Oncotarget. 2017;8:73947-73963 pubmed 出版商
Napolitano S, Martini G, Martinelli E, Belli V, Parascandolo A, Laukkanen M, et al. Therapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation. Oncotarget. 2017;8:67592-67604 pubmed 出版商
Li H, Yang D, Ning S, Xu Y, Yang F, Yin R, et al. Switching of the substrate specificity of protein tyrosine phosphatase N12 by cyclin-dependent kinase 2 phosphorylation orchestrating 2 oncogenic pathways. FASEB J. 2018;32:73-82 pubmed 出版商
Dai X, He Y, Yao W, Gao X. Establishment of a spontaneous metastasis tumor model for human ErbB-2 vaccine. Biomed Pharmacother. 2017;88:991-998 pubmed 出版商
Wielgos M, Rajbhandari R, Cooper T, Wei S, Nozell S, Yang E. Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors. Mol Cancer Res. 2017;15:340-347 pubmed 出版商
Pramanik A, Laha D, Dash S, Chattopadhyay S, Roy S, Das D, et al. An in-vivo study for targeted delivery of copper-organic complex to breast cancer using chitosan polymer nanoparticles. Mater Sci Eng C Mater Biol Appl. 2016;68:327-337 pubmed 出版商
Ma S, Henson E, Chen Y, Gibson S. Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Cell Death Dis. 2016;7:e2307 pubmed 出版商
Zhu M, Yao X, Wu M, Qian H, Wu Y, Chen Y. Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells. Mol Med Rep. 2016;13:1909-13 pubmed 出版商
Huang W, Wu Q, Zhang M, Kong Y, Cao P, Zheng W, et al. Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib. Cancer Lett. 2015;356:862-71 pubmed 出版商
Hosonaga M, Arima Y, Sugihara E, Kohno N, Saya H. Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells. Cancer Sci. 2014;105:779-87 pubmed 出版商
Carpenter R, Paw I, Dewhirst M, Lo H. Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells. Oncogene. 2015;34:546-57 pubmed 出版商
Slanina H, Mündlein S, Hebling S, Schubert Unkmeir A. Role of epidermal growth factor receptor signaling in the interaction of Neisseria meningitidis with endothelial cells. Infect Immun. 2014;82:1243-55 pubmed 出版商
Merkhofer E, Cogswell P, Baldwin A. Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha. Oncogene. 2010;29:1238-48 pubmed 出版商
Li Y, Pan Y, Wei Y, Cheng X, Zhou B, Tan M, et al. Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. Cancer Cell. 2004;6:459-69 pubmed
产品信息
目录号 :
16257
产品名称 :
HER2 WT
文章 :
doi10.1016/j.ccr.2004.09.027
id1776
pubmed_id15542430
细菌的抗性 :
氨苄西林
克隆 :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
起源 :
37
主要研究者 :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5HindIII
promoter
sequencing_primer_3BGHrev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2)
geneERBB2
id2064
genbank_ids
mutation
nameHER2
shRNA_sequence
size4400
species
9606
Homo sapiens
tags
抗性标记物 :
215
标签 :
High Copy
条款 :
Neomycin (select with G418)
更多信息或购买 :
公司信息
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
公司总部: 美国