产品简要
公司名称 :
Addgene
产品类型 :
cDNA
产品名称 :
pCI-neo Flag HAUSP
目录 :
16655
更多信息或购买 :
文章摘录数: 16
参考文献
Qiao H, Tian Y, Huo Y, Man H. Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice. iScience. 2022;25:104595 pubmed 出版商
Frey Y, Franz Wachtel M, Macek B, Olayioye M. Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7. Sci Rep. 2022;12:5036 pubmed 出版商
Sun Y, Chen J, Huang S, Su Y, Wang W, Agama K, et al. PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation. Nat Commun. 2021;12:5010 pubmed 出版商
Li C, Xia J, Franqui Machin R, Chen F, He Y, Ashby T, et al. TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies. J Clin Invest. 2021;131: pubmed 出版商
Zhang T, Periz G, Lu Y, Wang J. USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway. Proc Natl Acad Sci U S A. 2020;117:28114-28125 pubmed 出版商
Kim J, Yang Y, Park K, Ge X, Xu R, Li N, et al. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020;11:2289 pubmed 出版商
Franqui Machin R, Hao M, Bai H, Gu Z, Zhan X, Habelhah H, et al. Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma. J Clin Invest. 2018;: pubmed 出版商
Wang X, Zhang Q, Wang Y, Zhuang H, Chen B. Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms. Med Sci Monit. 2018;24:1742-1750 pubmed
Biswas K, Philip S, Yadav A, Martin B, Burkett S, Singh V, et al. BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage. Nat Commun. 2018;9:537 pubmed 出版商
Lamberto I, Liu X, Seo H, Schauer N, Iacob R, Hu W, et al. Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chem Biol. 2017;24:1490-1500.e11 pubmed 出版商
Mungamuri S, Qiao R, Yao S, Manfredi J, Gu W, Aaronson S. USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation. Cell Rep. 2016;14:2528-37 pubmed 出版商
Papp S, Huber A, Jordan S, Kriebs A, Nguyen M, Moresco J, et al. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. elife. 2015;4: pubmed 出版商
Zemp I, Lingner J. The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7. J Biol Chem. 2014;289:28595-606 pubmed 出版商
Hall J, Tabata M, Rodgers J, Puigserver P. USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Mol Endocrinol. 2014;28:912-24 pubmed 出版商
Khoronenkova S, Dianova I, Parsons J, Dianov G. USP7/HAUSP stimulates repair of oxidative DNA lesions. Nucleic Acids Res. 2011;39:2604-9 pubmed 出版商
Cummins J, Vogelstein B. HAUSP is required for p53 destabilization. Cell Cycle. 2004;3:689-92 pubmed
产品信息
目录号 :
16655
产品名称 :
pCI-neo Flag HAUSP
文章 :
doi10.4161/cc.3.6.924
id1879
pubmed_id15118411
细菌的抗性 :
氨苄西林
克隆 :
backbonepCI-Neo
backbone_mutation
backbone_originPromega
backbone_size5472
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
生长记录 :
A fragment of human HAUSP cDNA including the entire ORF was cloned into pCI-neo at the NheI and XbaI sites. (Please note that the XbaI site is blocked by overlapping methylation). A sequence including the Flag tag was added to one of the primers so that the encoded protein contains a Flag tag at the N-terminus.
起源 :
37
主要研究者 :
alt_names
USP7
ubiquitin specific peptidase 7
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5NheI
promoterCMV
sequencing_primer_3EBV-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesC16DELp13.2, DEL16P13.2, HAFOUS, HAUSP, TEF1
geneUSP7
id7874
genbank_ids
mutation
nameHAUSP
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
抗性标记物 :
553
标签 :
未知
条款 :
Neomycin (select with G418)
更多信息或购买 :
公司信息
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
公司总部: 美国