产品简要
公司名称 :
Addgene
产品类型 :
cDNA
产品名称 :
pDONR223-血小板源性生长因子受体
目录 :
23892
更多信息或购买 :
文章摘录数: 9
参考文献
Rogers M, Campa xf1 a M, Long R, Fantauzzo K. PDGFR dimer-specific activation, trafficking and downstream signaling dynamics. J Cell Sci. 2022;135: pubmed 出版商
Salokas K, Liu X, Ohman T, Chowdhury I, Gawriyski L, Keskitalo S, et al. Physical and functional interactome atlas of human receptor tyrosine kinases. EMBO Rep. 2022;23:e54041 pubmed 出版商
Hamada T, Akahane T, Yokoyama S, Higa N, Kirishima M, Matsuo K, et al. An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors. Sci Rep. 2022;12:1275 pubmed 出版商
Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, et al. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. Cell Rep Med. 2020;1:100002 pubmed 出版商
Drinane M, Yaqoob U, Yu H, Luo F, Greuter T, Arab J, et al. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. JCI Insight. 2017;2: pubmed 出版商
Gao Z, Daquinag A, Su F, Snyder B, Kolonin M. PDGFRα/PDGFRβ signaling balance modulates progenitor cell differentiation into white and beige adipocytes. Development. 2018;145: pubmed 出版商
Chen L, Chai K. Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Oncotarget. 2017;8:56490-56505 pubmed 出版商
Liau B, Sievers C, Donohue L, Gillespie S, Flavahan W, Miller T, et al. Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell. 2017;20:233-246.e7 pubmed 出版商
Johannessen C, Boehm J, Kim S, Thomas S, Wardwell L, Johnson L, et al. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature. 2010;468:968-72 pubmed 出版商
产品信息
目录号 :
23892
产品名称 :
pDONR223-血小板源性生长因子受体
文章 :
doi10.1038/nature09627
id3878
pubmed_id21107320
细菌的抗性 :
大观霉素
克隆 :
backbonepDONR223
backbone_mutation
backbone_originInvitrogen
backbone_size5005
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Other
Gateway Donor vector
生长记录 :
The ORF has no Stop codon. This design enables easy recombination into a destination vector to add an epitope tag of choice and Stop codon to the ORF. Do NOT use this plasmid directly for transfections. A set of 4 custom lentiviral vectors is available ( pLX301 (http://www.addgene.org/25895/) , pLX302 (http://www.addgene.org/25896/) , pLX303 (http://www.addgene.org/25897/) , pLX304 (http://www.addgene.org/25890/) ) to be used to express these ORFs in mammalian cells. These plasmids are not included in the kit and must be ordered separately.
起源 :
37
主要研究者 :
alt_names
platelet-derived growth factor receptor, alpha polypeptide
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3M13rev
sequencing_primer_5M13pUC-fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD140A, PDGFR-2, PDGFR2
genePDGFRA
id5156
genbank_ids
mutationM260I
namePDGFRA
shRNA_sequence
size3270
species
9606
Homo sapiens
tags
抗性标记物 :
184
423
标签 :
High Copy
更多信息或购买 :
公司信息
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
公司总部: 美国