pDONR223-血小板衍生的生长因子受体b

产品简要

公司名称 :

Addgene

产品类型 :

cDNA

产品名称 :

pDONR223-血小板衍生的生长因子受体b

23893

更多信息或购买 :

Addgene 产品网页

文章摘录数: 8

参考文献
Rogers M, Campa xf1 a M, Long R, Fantauzzo K. PDGFR dimer-specific activation, trafficking and downstream signaling dynamics. J Cell Sci. 2022;135: pubmed 出版商
Drinane M, Yaqoob U, Yu H, Luo F, Greuter T, Arab J, et al. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. JCI Insight. 2017;2: pubmed 出版商
Gao Z, Daquinag A, Su F, Snyder B, Kolonin M. PDGFRα/PDGFRβ signaling balance modulates progenitor cell differentiation into white and beige adipocytes. Development. 2018;145: pubmed 出版商
Brady D, Crowe M, Greenberg D, Counter C. Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors. Cancer Res. 2017;77:6240-6252 pubmed 出版商
Chen L, Chai K. Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Oncotarget. 2017;8:56490-56505 pubmed 出版商
Manole S, Richards E, Meyer A. JNK Pathway Activation Modulates Acquired Resistance to EGFR/HER2-Targeted Therapies. Cancer Res. 2016;76:5219-28 pubmed 出版商
Bugaj L, Spelke D, Mesuda C, Varedi M, Kane R, Schaffer D. Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Nat Commun. 2015;6:6898 pubmed 出版商
Johannessen C, Boehm J, Kim S, Thomas S, Wardwell L, Johnson L, et al. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature. 2010;468:968-72 pubmed 出版商

产品信息

目录号 :

23893

产品名称 :

pDONR223-血小板衍生的生长因子受体b

文章 :

doi	10.1038/nature09627
id	3878
pubmed_id	21107320

细菌的抗性 :

大观霉素

克隆 :

backbone

pDONR223

backbone_mutation

backbone_origin

Invitrogen

backbone_size

5005

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Other

Gateway Donor vector

生长记录 :

The ORF has no Stop codon. This design enables easy recombination into a destination vector to add an epitope tag of choice and Stop codon to the ORF. Do NOT use this plasmid directly for transfections. A set of 4 custom lentiviral vectors is available ( pLX301 (http://www.addgene.org/25895/) , pLX302 (http://www.addgene.org/25896/) , pLX303 (http://www.addgene.org/25897/) , pLX304 (http://www.addgene.org/25890/) ) to be used to express these ORFs in mammalian cells. These plasmids are not included in the kit and must be ordered separately.

起源 :

主要研究者 :

alt_names

platelet-derived growth factor receptor, beta polypeptide

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3	M13rev
sequencing_primer_5	M13pUC-fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT
gene	PDGFRB
id	5159

genbank_ids

mutation

name

PDGFRB

shRNA_sequence

size

3321

species

9606

Homo sapiens