产品简要
公司名称 :
Addgene
产品类型 :
cDNA
产品名称 :
pCLE NICD3
目录 :
26894
更多信息或购买 :
文章摘录数: 13
参考文献
Chen W, Zhang Y, Li R, Huang W, Wei X, Zeng D, et al. Notch3 Transactivates Glycogen Synthase Kinase-3-Beta and Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer Cells. Cells. 2022;11: pubmed 出版商
Zhang Y, Liang Y, Wu Y, Chen M, Chen W, Li R, et al. Notch3 inhibits cell proliferation and tumorigenesis and predicts better prognosis in breast cancer through transactivating PTEN. Cell Death Dis. 2021;12:502 pubmed 出版商
Han Q, Han F, Fan Y, Lian B, Xiao J, Sun W, et al. Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF-2α. Oncol Lett. 2020;20:379 pubmed 出版商
Wu Y, Yuan M, Wu H, Chen W, Zhang M, Ye Q, et al. MicroRNA-488 inhibits proliferation and motility of tumor cells via downregulating FSCN1, modulated by Notch3 in breast carcinomas. Cell Death Dis. 2020;11:912 pubmed 出版商
Ganguly S, Hostetter G, Tang L, Frank S, Saboda K, Mehra R, et al. Notch3 promotes prostate cancer-induced bone lesion development via MMP-3. Oncogene. 2020;39:204-218 pubmed 出版商
Papadakos K, Bartoschek M, Rodriguez C, Gialeli C, Jin S, Lendahl U, et al. Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling. Matrix Biol. 2018;: pubmed 出版商
Liang Y, Lin H, Dou X, Chen M, Wei X, Zhang Y, et al. MiR-221/222 promote epithelial-mesenchymal transition by targeting Notch3 in breast cancer cell lines. NPJ Breast Cancer. 2018;4:20 pubmed 出版商
Lin H, Liang Y, Dou X, Chen C, Wei X, Zeng D, et al. Notch3 inhibits epithelial-mesenchymal transition in breast cancer via a novel mechanism, upregulation of GATA-3 expression. Oncogenesis. 2018;7:59 pubmed 出版商
Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti Bugaeva O, Paatero I, et al. Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. elife. 2018;7: pubmed 出版商
Dou X, Liang Y, Lin H, Wei X, Zhang Y, Bai J, et al. Notch3 Maintains Luminal Phenotype and Suppresses Tumorigenesis and Metastasis of Breast Cancer via Trans-Activating Estrogen Receptor-?. Theranostics. 2017;7:4041-4056 pubmed 出版商
Morgan K, Fischer B, Lee F, Shah J, Bertino J, Rosenfeld J, et al. Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma. Mol Cancer Ther. 2017;16:2759-2769 pubmed 出版商
Gomi K, Arbelaez V, Crystal R, Walters M. Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway. PLoS ONE. 2015;10:e0116507 pubmed 出版商
Dang L, Yoon K, Wang M, Gaiano N. Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon. Dev Neurosci. 2006;28:58-69 pubmed
产品信息
目录号 :
26894
产品名称 :
pCLE NICD3
文章 :
doi10.1159/000090753
id6979
pubmed_id16508304
细菌的抗性 :
氨苄西林
克隆 :
backbonepCLE
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
生长记录 :
EF1a xenopus enhancer-promoter-hNICD3-IRES-AlkPhos A1757T mutation in Notch3 is not known to affect function.
生长温度 :
May be slow-growing. Culturing for up to 48 hours under selection may be necessary to achieve robust growth
起源 :
37
主要研究者 :
alt_names
Notch3 intracellular domain
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5EF-1a-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCADASIL, CADASIL1, CASIL, IMF2, LMNS
geneNOTCH3
id4854
genbank_ids
mutation
nameNICD3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagIRES
locationC terminal on backbone
tagAlkaline Phosphatase
抗性标记物 :
155
标签 :
High Copy
更多信息或购买 :
公司信息
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
公司总部: 美国