产品简要
公司名称 :
Addgene
产品类型 :
cDNA
产品名称 :
pRK5-EGFP-Tau
目录 :
46904
更多信息或购买 :
文章摘录数: 29
参考文献
Lopez D, Maltby C, Warming H, Divecha N, Vargas Caballero M, Coldwell M, et al. A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau. Front Neurosci. 2023;17:1196007 pubmed 出版商
Tao X, Liu J, Diaz Perez Z, Foley J, Stewart T, Casero R, et al. Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy. bioRxiv. 2023;: pubmed 出版商
Rajbanshi B, Guruacharya A, Mandell J, Bloom G. Localization, induction, and cellular effects of tau phosphorylated at threonine 217. Alzheimers Dement. 2023;19:2874-2887 pubmed 出版商
Hill S, Esquivel A, Ospina S, Rahal L, Dickey C, Blair L. Chaperoning activity of the cyclophilin family prevents tau aggregation. Protein Sci. 2022;31:e4448 pubmed 出版商
Kim K, Park S, Hong J, Koh J, Cho D, Hwang J, et al. Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly. Front Cell Neurosci. 2022;16:895750 pubmed 出版商
Peinado J, Chaplot K, Jarvela T, Barbieri E, Shorter J, Lindberg I. Sequestration of TDP-43216-414 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. ACS Chem Neurosci. 2022;13:1651-1665 pubmed 出版商
Norambuena A, Sun X, Wallrabe H, Cao R, Sun N, Pardo E, et al. SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-β oligomers. Neurobiol Dis. 2022;169:105737 pubmed 出版商
Torres Garcia L, P Domingues J, Brandi E, Haikal C, Mudannayake J, Brás I, et al. Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation. Sci Rep. 2022;12:2987 pubmed 出版商
Cook B, Walker N, Zhang Q, Chen S, Evans T. The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3-beta signaling. J Biol Chem. 2021;296:100696 pubmed 出版商
Paul S, Dansithong W, Figueroa K, Gandelman M, Scoles D, Pulst S. Staufen1 in Human Neurodegeneration. Ann Neurol. 2021;89:1114-1128 pubmed 出版商
Giovinazzo D, Bursać B, Sbodio J, Nalluru S, Vignane T, Snowman A, et al. Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Mahendran T, Suresh S, Garimella L, Manjithaya R. Soluble 4R0N Tau Abrogates Endocytic Vesicular Dynamics. Front Aging Neurosci. 2020;12:537712 pubmed 出版商
Park L, Hochrainer K, Hattori Y, Ahn S, Anfray A, Wang G, et al. Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration. Nat Neurosci. 2020;23:1079-1089 pubmed 出版商
Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed 出版商
Hallinan G, Vargas Caballero M, West J, Deinhardt K. Tau Misfolding Efficiently Propagates between Individual Intact Hippocampal Neurons. J Neurosci. 2019;39:9623-9632 pubmed 出版商
Li D, Cho Y. High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay. J Neurochem. 2020;152:122-135 pubmed 出版商
Teravskis P, Oxnard B, Miller E, Kemper L, Ashe K, Liao D. Phosphorylation in two discrete tau domains regulates a stepwise process leading to postsynaptic dysfunction. J Physiol. 2019;: pubmed 出版商
Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed 出版商
Vaz Silva J, Gomes P, Jin Q, Zhu M, Zhuravleva V, Quintremil S, et al. Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction. EMBO J. 2018;37: pubmed 出版商
St Amand M, Bond M, Riedy J, Comly M, Shiloach J, Hanover J. A genetic model to study O-GlcNAc cycling in immortalized mouse embryonic fibroblasts. J Biol Chem. 2018;293:13673-13681 pubmed 出版商
Li D, Wang L, Maziuk B, Yao X, Wolozin B, Cho Y. Directed evolution of a picomolar-affinity, high-specificity antibody targeting phosphorylated tau. J Biol Chem. 2018;293:12081-12094 pubmed 出版商
Xu Y, Cui L, DiBello A, Wang L, Lee J, Saidi L, et al. DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins. Cell Discov. 2018;4:11 pubmed 出版商
Lu M, Liu T, Jiao Q, Ji J, Tao M, Liu Y, et al. Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway. Eur J Med Chem. 2018;146:251-259 pubmed 出版商
Gosavi P, Houghton F, McMillan P, Hanssen E, Gleeson P. The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity. J Cell Sci. 2018;131: pubmed 出版商
Rodriguez Rodriguez P, Sandebring Matton A, Merino Serrais P, Parrado Fernandez C, Rabano A, Winblad B, et al. Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons. Brain. 2017;: pubmed 出版商
Wang Y, Hall R, Lee M, Kamgar Parsi A, Bi X, Baudry M. The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation. Sci Rep. 2017;7:11771 pubmed 出版商
Ji C, Tang M, Johnson G. Assessing the degradation of tau in primary neurons: The role of autophagy. Methods Cell Biol. 2017;141:229-244 pubmed 出版商
Lasagna Reeves C, de Haro M, Hao S, Park J, Rousseaux M, Al Ramahi I, et al. Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model. Neuron. 2016;92:407-418 pubmed 出版商
Hoover B, Reed M, Su J, Penrod R, Kotilinek L, Grant M, et al. Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron. 2010;68:1067-81 pubmed 出版商
产品信息
目录号 :
46904
产品名称 :
pRK5-EGFP-Tau
文章 :
doi10.1016/j.neuron.2010.11.030
id6986
pubmed_id21172610
细菌的抗性 :
氨苄西林
克隆 :
backbonepRK5
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
生长株 :
expresses EGFP tagged Tau in mammalian cells
起源 :
37
主要研究者 :
alt_names
Tau
microtubule-associated protein tau
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5Cla1
promoterCMV
sequencing_primer_3SV40pA-R
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, Tau-PHF6, tau-40
geneMAPT
id4137
genbank_ids
mutationThis WT htau construct contains human four-repeat tau lacking the N-terminal sequences (4R0N) and contains exons 1, 4 and 5, 7, and 9 13, intron 13, and exon 14
nameMAPT
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
抗性标记物 :
1642
标签 :
未知
更多信息或购买 :
公司信息
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
公司总部: 美国