公司名称 :
产品类型 :
产品名称 :
lenti MS2-P65-HSF1_Hygro
目录 :
更多信息或购买 :
文章摘录数: 114
Li Y, Tan M, Sun S, Stea E, Pang B. Targeted CRISPR activation and knockout screenings identify novel doxorubicin transporters. Cell Oncol (Dordr). 2023;: pubmed 出版商
Shamloo S, Kloetgen A, Petroulia S, Hockemeyer K, Sievers S, Tsirigos A, et al. Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma. Biomedicines. 2023;11: pubmed 出版商
Couto J, Vulin M, Jehanno C, Coissieux M, Hamelin B, Schmidt A, et al. Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer. EMBO J. 2023;42:e112559 pubmed 出版商
Gil N, Perry R, Mukamel Z, Tuck A, B xfc hler M, Ulitsky I. Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus. Cell Rep. 2023;42:112569 pubmed 出版商
Shi J, Xin H, Shao Y, Dai S, Tan N, Li Z, et al. CRISPR-Based KCC2 Upregulation Attenuates Drug-Resistant Seizure in Mouse Models of Epilepsy. Ann Neurol. 2023;94:91-105 pubmed 出版商
King C, Liu Y, Amato K, Schaack G, Hu T, Smith J, et al. Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection. bioRxiv. 2023;: pubmed 出版商
Jin Q, Liu X, Zhuang Z, Huang J, Gou S, Shi H, et al. Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation. Genome Biol. 2023;24:8 pubmed 出版商
Wang N, He J, Feng X, Liao S, Zhao Y, Tang F, et al. Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8. elife. 2023;12: pubmed 出版商
Zhang X, Luo Y, Cen Y, Qiu X, Li J, Jie M, et al. MACC1 promotes pancreatic cancer metastasis by interacting with the EMT regulator SNAI1. Cell Death Dis. 2022;13:923 pubmed 出版商
Paris A, Tardif N, Baietti F, Berra C, Leclair H, Leucci E, et al. The AhR-SRC axis as a therapeutic vulnerability in BRAFi-resistant melanoma. EMBO Mol Med. 2022;14:e15677 pubmed 出版商
Zhang X, Jiang Q, Li J, Zhang S, Cao Y, Xia X, et al. KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA-DNA triplexes and HP1 binding. Nat Cell Biol. 2022;24:1617-1629 pubmed 出版商
Hou G, Zhou T, Xu N, Yin Z, Zhu X, Zhang Y, et al. Integrative functional genomics identifies SLE causal genetic variant in the IRF5 risk locus. Arthritis Rheumatol. 2022;: pubmed 出版商
Beucher A, Miguel Escalada I, Balboa D, De Vas M, Maestro M, García Hurtado J, et al. The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A. Nat Cell Biol. 2022;24:1528-1540 pubmed 出版商
Khatib J, Schleicher E, Jackson L, Dhoonmoon A, Moldovan G, Nicolae C. Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival. Oncotarget. 2022;13:1078-1091 pubmed 出版商
Voloudakis G, Vicari J, Venkatesh S, Hoffman G, Dobrindt K, Zhang W, et al. A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility. NPJ Genom Med. 2022;7:52 pubmed 出版商
Shevchenko A, Rifel N, Zakian S, Zakharova I. Constitutive heterochromatin propagation contributes to the X chromosome inactivation. Chromosome Res. 2022;30:289-307 pubmed 出版商
Fu H, Wang T, Kong X, Yan K, Yang Y, Cao J, et al. A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells. Nat Commun. 2022;13:3984 pubmed 出版商
Yu C, Lei X, Chen F, Mao S, Lv L, Liu H, et al. ARID1A loss derepresses a group of human endogenous retrovirus-H loci to modulate BRD4-dependent transcription. Nat Commun. 2022;13:3501 pubmed 出版商
Zhang Q, Wang S, Li W, Yau E, Hui H, Singh P, et al. Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration. Nucleic Acids Res. 2022;: pubmed 出版商
Huang M, Yang F, Zhang D, Lin M, Duan H, El Mayta R, et al. Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction. Nat Cardiovasc Res. 2022;1:372-388 pubmed 出版商
Feser C, Lees C, Lammers D, Riddle M, Bingham J, Eckert M, et al. Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production. Int J Mol Sci. 2022;23: pubmed 出版商
Zhou T, Zhu X, Ye Z, Wang Y, Yao C, Xu N, et al. Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery. Nat Commun. 2022;13:1855 pubmed 出版商
Giehrl Schwab J, Giesert F, Rauser B, Lao C, Hembach S, Lefort S, et al. Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons. EMBO Mol Med. 2022;14:e14797 pubmed 出版商
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed 出版商
Sofer S, Lamkiewicz K, Armoza Eilat S, Partouche S, Marz M, Moskovits N, et al. A genome-wide CRISPR activation screen reveals Hexokinase 1 as a critical factor in promoting resistance to multi-kinase inhibitors in hepatocellular carcinoma cells. FASEB J. 2022;36:e22191 pubmed 出版商
Hirakawa M, Tjahjono N, Light Y, Celebi A, Celebi N, Chintalapudi P, et al. Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties. iScience. 2022;25:103759 pubmed 出版商
Grinkevitch V, Wappett M, Crawford N, Price S, Lees A, McCann C, et al. Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists. Mol Cancer Ther. 2022;21:594-606 pubmed 出版商
Jiang L, Liang J, Huang W, Ma J, Park K, Wu Z, et al. CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Mol Ther. 2022;30:54-74 pubmed 出版商
Ikeuchi W, Wakita Y, Zhang G, Li C, Itakura K, Yamakawa T. AT-rich interaction domain 5A regulates the transcription of interleukin-6 gene in prostate cancer cells. Prostate. 2022;82:97-106 pubmed 出版商
Dhungel B, Monteuuis G, Giardina C, Tabar M, Feng Y, Metierre C, et al. The Fusion of CLEC12A and MIR223HG Arises from a trans-Splicing Event in Normal and Transformed Human Cells. Int J Mol Sci. 2021;22: pubmed 出版商
Peng W, Koirala P, Zhou H, Jiang J, Zhang Z, Yang L, et al. Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer. Cell Death Dis. 2021;12:1000 pubmed 出版商
Zhu S, Liu Y, Zhou Z, Zhang Z, Xiao X, Liu Z, et al. Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry. Sci China Life Sci. 2021;: pubmed 出版商
Perez García V, Lea G, Lopez Jimenez P, Okkenhaug H, Burton G, Moffett A, et al. BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion. elife. 2021;10: pubmed 出版商
Ramaker R, Hardigan A, Gordon E, Wright C, Myers R, Cooper S. Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition. BMC Cancer. 2021;21:632 pubmed 出版商
Alda Catalinas C, Eckersley Maslin M, Reik W. Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells. STAR Protoc. 2021;2:100426 pubmed 出版商
Tian C, Huang Y, Clauser K, Rickelt S, Lau A, Carr S, et al. Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells. Nat Commun. 2021;12:2328 pubmed 出版商
Zilli F, Marques Ramos P, Auf der Maur P, Jehanno C, Sethi A, Coissieux M, et al. The NFIB-ERO1A axis promotes breast cancer metastatic colonization of disseminated tumour cells. EMBO Mol Med. 2021;13:e13162 pubmed 出版商
Hou G, Harley I, Lu X, Zhou T, Xu N, Yao C, et al. SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression. Nat Commun. 2021;12:135 pubmed 出版商
Shin H, Kweon J, Kim Y. Gene Manipulation Using Fusion Guide RNAs for Cas9 and Cas12a. Methods Mol Biol. 2021;2162:185-193 pubmed 出版商
Clements K, Schleicher E, Thakar T, Hale A, Dhoonmoon A, Tolman N, et al. Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens. Nat Commun. 2020;11:6118 pubmed 出版商
Schleicher E, Dhoonmoon A, Jackson L, Clements K, Stump C, Nicolae C, et al. Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors. PLoS Genet. 2020;16:e1009176 pubmed 出版商
Chen C, Enomoto A, Weng L, Taki T, Shiraki Y, Mii S, et al. Complex roles of the actin-binding protein Girdin/GIV in DNA damage-induced apoptosis of cancer cells. Cancer Sci. 2020;111:4303-4317 pubmed 出版商
Alda Catalinas C, Bredikhin D, Hernando Herraez I, Santos F, Kubinyecz O, Eckersley Maslin M, et al. A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program. Cell Syst. 2020;11:25-41.e9 pubmed 出版商
Kirchner S, Reuter S, Westphal A, Mrowka R. Decipher the complexity of cis-regulatory regions by a modified Cas9. PLoS ONE. 2020;15:e0235530 pubmed 出版商
Liao Z, Lee J, Krakowiak J, Wang R, Li W. Enforced Activation of Enhancer RNAs In Situ through the dCas9 Synergistic Activation Mediator System. J Vis Exp. 2020;: pubmed 出版商
Nasrallah R, Imianowski C, Bossini Castillo L, Grant F, Dogan M, Placek L, et al. A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells. Nature. 2020;583:447-452 pubmed 出版商
Yu L, Wang L, Yi H, Wu X. LRP6-CRISPR prevents activation of hepatic stellate cells and liver fibrogenesis in rats. Am J Transl Res. 2020;12:397-408 pubmed
Petazzi P, Torres Ruiz R, Fidanza A, Roca Ho H, Gutiérrez Agüera F, Castaño J, et al. Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells. Mol Ther Nucleic Acids. 2020;20:196-204 pubmed 出版商
Huang H, Zhong L, Zhou J, Hou Y, Zhang Z, Xing X, et al. Leydig-like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats. J Cell Mol Med. 2020;24:3971-3981 pubmed 出版商
Raffeiner P, Hart J, García Caballero D, Bar Peled L, Weinberg M, Vogt P. An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation. Proc Natl Acad Sci U S A. 2020;117:6571-6579 pubmed 出版商
Wang J, Jiang X, Zhao L, Zuo S, Chen X, Zhang L, et al. Lineage reprogramming of fibroblasts into induced cardiac progenitor cells by CRISPR/Cas9-based transcriptional activators. Acta Pharm Sin B. 2020;10:313-326 pubmed 出版商
Mong E, Yang Y, Akat K, Canfield J, VanWye J, Lockhart J, et al. Chromosome 19 microRNA cluster enhances cell reprogramming by inhibiting epithelial-to-mesenchymal transition. Sci Rep. 2020;10:3029 pubmed 出版商
Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez Priego C, et al. DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. Cell Stem Cell. 2020;26:234-250.e7 pubmed 出版商
Tian C, Ohlund D, Rickelt S, Lidström T, Huang Y, Hao L, et al. Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2020;80:1461-1474 pubmed 出版商
Li K, Liu Y, Cao H, Zhang Y, Gu Z, Liu X, et al. Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing. Nat Commun. 2020;11:485 pubmed 出版商
Roberston M, Raghunathan S, Potaman V, Zhang F, Stewart M, McConnell B, et al. CRISPR-Cas9-induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expression. FASEB J. 2020;34:555-570 pubmed 出版商
Deng X, Li S, Kong F, Ruan H, Xu X, Zhang X, et al. Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer. Theranostics. 2020;10:265-280 pubmed 出版商
Sajwan S, Mannervik M. Gene activation by dCas9-CBP and the SAM system differ in target preference. Sci Rep. 2019;9:18104 pubmed 出版商
Trigg R, Lee L, Prokoph N, Jahangiri L, Reynolds C, Amos Burke G, et al. The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status. Nat Commun. 2019;10:5428 pubmed 出版商
Zhang S, Feng S, Jiang W, Huang X, Chen J. Construction and optimization of a base editor based on the MS2 system. Animal Model Exp Med. 2019;2:185-190 pubmed 出版商
Weiterer S, Meier Soelch J, Georgomanolis T, Mizi A, Beyerlein A, Weiser H, et al. Distinct IL-1α-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner. EMBO J. 2019;:e101533 pubmed 出版商
Singaravelu R, Ahmed N, Quan C, Srinivasan P, Ablenas C, Roy D, et al. A conserved miRNA-183 cluster regulates the innate antiviral response. J Biol Chem. 2019;294:19785-19794 pubmed 出版商
Griukova A, Deryabin P, Shatrova A, Burova E, Severino V, Farina A, et al. Molecular basis of senescence transmitting in the population of human endometrial stromal cells. Aging (Albany NY). 2019;11:9912-9931 pubmed 出版商
Peng W, Koirala P, Zhang W, Ni C, Wang Z, Yang L, et al. lncRNA RMST Enhances DNMT3 Expression through Interaction with HuR. Mol Ther. 2019;: pubmed 出版商
Zhang Z, Lee J, Ruan H, Ye Y, Krakowiak J, Hu Q, et al. Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer. Nat Commun. 2019;10:4562 pubmed 出版商
Luo M, Bai J, Liu B, Yan P, Zuo F, Sun H, et al. H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling. Stem Cell Reports. 2019;13:642-656 pubmed 出版商
Chen Y, Huang Y, Kanwal M, Li G, Yang J, Niu H, et al. MUC16 in non-small cell lung cancer patients affected by familial lung cancer and indoor air pollution: clinical characteristics and cell behaviors. Transl Lung Cancer Res. 2019;8:476-488 pubmed 出版商
Tong Z, Sathe A, Ebner B, Qi P, Veltkamp C, Gschwend J, et al. Functional genomics identifies predictive markers and clinically actionable resistance mechanisms to CDK4/6 inhibition in bladder cancer. J Exp Clin Cancer Res. 2019;38:322 pubmed 出版商
Pentinmikko N, Iqbal S, Mana M, Andersson S, Cognetta A, Suciu R, et al. Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. Nature. 2019;571:398-402 pubmed 出版商
Pontis J, Planet E, Offner S, Turelli P, Duc J, Coudray A, et al. Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs. Cell Stem Cell. 2019;24:724-735.e5 pubmed 出版商
Toska E, Castel P, Chhangawala S, Arruabarrena Aristorena A, Chan C, Hristidis V, et al. PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression. Cell Rep. 2019;27:294-306.e5 pubmed 出版商
Shen M, Wang F, Li M, Sah N, Stockton M, Tidei J, et al. Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nat Neurosci. 2019;22:386-400 pubmed 出版商
Lu B, Klingbeil O, Tarumoto Y, Somerville T, Huang Y, Wei Y, et al. A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. Cancer Cell. 2018;34:970-981.e8 pubmed 出版商
Chong Z, Ohnishi S, Yusa K, Wright G. Pooled extracellular receptor-ligand interaction screening using CRISPR activation. Genome Biol. 2018;19:205 pubmed 出版商
Zhang P, Kang B, Xie G, Li S, Gu Y, Shen Y, et al. Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer. Cancer Lett. 2018;442:53-67 pubmed 出版商
Liu L, Huang M, Dai P, Liu T, Fan S, Cheng X, et al. Intrinsic Nucleotide Preference of Diversifying Base Editors Guides Antibody Ex Vivo Affinity Maturation. Cell Rep. 2018;25:884-892.e3 pubmed 出版商
Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed 出版商
Zhang Y, Arango G, Li F, Xiao X, Putatunda R, Yu J, et al. Comprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profiling. BMC Med Genomics. 2018;11:78 pubmed 出版商
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed 出版商
Bester A, Lee J, Chavez A, Lee Y, Nachmani D, Vora S, et al. An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. Cell. 2018;173:649-664.e20 pubmed 出版商
Jia Y, Xu R, Ren X, Ewen Campen B, Rajakumar R, ZIRIN J, et al. Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Proc Natl Acad Sci U S A. 2018;115:4719-4724 pubmed 出版商
Vad Nielsen J, Nielsen A, Luo Y. Simple method for assembly of CRISPR synergistic activation mediator gRNA expression array. J Biotechnol. 2018;274:54-57 pubmed 出版商
Passaia B, Dias M, Kremer J, Antonini S, de Almeida M, Fragoso M, et al. TCF21/POD-1, a Transcritional Regulator of SF-1/NR5A1, as a Potential Prognosis Marker in Adult and Pediatric Adrenocortical Tumors. Front Endocrinol (Lausanne). 2018;9:38 pubmed 出版商
Guallar D, Bi X, Pardavila J, Huang X, Sáenz C, Shi X, et al. RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells. Nat Genet. 2018;50:443-451 pubmed 出版商
Palau A, Garz A, Diesch J, Zwick A, Malinverni R, Valero V, et al. Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes. Oncotarget. 2017;8:115002-115017 pubmed 出版商
Lu J, Zhao C, Zhao Y, Zhang J, Zhang Y, Chen L, et al. Multimode drug inducible CRISPR/Cas9 devices for transcriptional activation and genome editing. Nucleic Acids Res. 2018;46:e25 pubmed 出版商
Liao H, Hatanaka F, Araoka T, Reddy P, Wu M, Sui Y, et al. In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation. Cell. 2017;171:1495-1507.e15 pubmed 出版商
Moretti A, Pavanelli J, Nolasco P, Leisegang M, Tanaka L, Fernandes C, et al. Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families. Sci Rep. 2017;7:17262 pubmed 出版商
Kweon J, Jang A, Kim D, Yang J, Yoon M, Rim Shin H, et al. Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1. Nat Commun. 2017;8:1723 pubmed 出版商
Bonev B, Mendelson Cohen N, Szabo Q, Fritsch L, Papadopoulos G, Lubling Y, et al. Multiscale 3D Genome Rewiring during Mouse Neural Development. Cell. 2017;171:557-572.e24 pubmed 出版商
Lundh M, Plucińska K, Isidor M, Petersen P, Emanuelli B. Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA. Mol Metab. 2017;6:1313-1320 pubmed 出版商
Li S, Zhang A, Xue H, Li D, Liu Y. One-Step piggyBac Transposon-Based CRISPR/Cas9 Activation of Multiple Genes. Mol Ther Nucleic Acids. 2017;8:64-76 pubmed 出版商
Liu S, Yu X, Wang Q, Liu Z, Xiao Q, Hou P, et al. Specific Expression of Interferon-? Induced by Synergistic Activation Mediator-Derived Systems Activates Innate Immunity and Inhibits Tumorigenesis. J Microbiol Biotechnol. 2017;27:1855-1866 pubmed 出版商
Ewen Campen B, Yang Zhou D, Fernandes V, González D, Liu L, Tao R, et al. Optimized strategy for in vivo Cas9-activation in Drosophila. Proc Natl Acad Sci U S A. 2017;114:9409-9414 pubmed 出版商
Joung J, Engreitz J, Konermann S, Abudayyeh O, Verdine V, Aguet F, et al. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. 2017;548:343-346 pubmed 出版商
Ho S, Hartley B, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, et al. Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Stem Cell Reports. 2017;9:615-628 pubmed 出版商
Fidanza A, Lopez Yrigoyen M, Romano N, Jones R, Taylor A, Forrester L. An all-in-one UniSam vector system for efficient gene activation. Sci Rep. 2017;7:6394 pubmed 出版商
Nowicki Osuch K, Li Y, Challinor M, Gerrard D, Hanley N, Sharrocks A. EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas. PLoS ONE. 2017;12:e0181902 pubmed 出版商
Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed 出版商
Tammela T, Sanchez Rivera F, Cetinbas N, Wu K, Joshi N, Helenius K, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017;545:355-359 pubmed 出版商
Solvsten C, Daugaard T, Luo Y, de Paoli F, Christensen J, Nielsen A. The Effects of Voluntary Physical Exercise-Activated Neurotrophic Signaling in Rat Hippocampus on mRNA Levels of Downstream Signaling Molecules. J Mol Neurosci. 2017;62:142-153 pubmed 出版商
Joung J, Konermann S, Gootenberg J, Abudayyeh O, Platt R, Brigham M, et al. Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nat Protoc. 2017;12:828-863 pubmed 出版商
Schwarz K, Daringer N, Dolberg T, Leonard J. Rewiring human cellular input-output using modular extracellular sensors. Nat Chem Biol. 2017;13:202-209 pubmed 出版商
Xiong K, Zhou Y, Hyttel P, Bolund L, Freude K, Luo Y. Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM). Stem Cell Res. 2016;17:665-669 pubmed 出版商
Hess G, Frésard L, Han K, Lee C, Li A, Cimprich K, et al. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nat Methods. 2016;13:1036-1042 pubmed 出版商
Zhu S, Li W, Liu J, Chen C, Liao Q, Xu P, et al. Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library. Nat Biotechnol. 2016;34:1279-1286 pubmed 出版商
Ho T, Huang J, Zhou N, Zhang Z, Koirala P, Zhou X, et al. Regulation of PCGEM1 by p54/nrb in prostate cancer. Sci Rep. 2016;6:34529 pubmed 出版商
Chavez A, Tuttle M, Pruitt B, Ewen Campen B, Chari R, Ter Ovanesyan D, et al. Comparison of Cas9 activators in multiple species. Nat Methods. 2016;13:563-567 pubmed 出版商
Kennedy E, Bogerd H, Kornepati A, Kang D, Ghoshal D, Marshall J, et al. Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host Microbe. 2016;19:675-85 pubmed 出版商
Bogerd H, Kornepati A, Marshall J, Kennedy E, Cullen B. Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators. Proc Natl Acad Sci U S A. 2015;112:E7249-56 pubmed 出版商
Limsirichai P, Gaj T, Schaffer D. CRISPR-mediated Activation of Latent HIV-1 Expression. Mol Ther. 2016;24:499-507 pubmed 出版商
Saayman S, Lazar D, Scott T, Hart J, Takahashi M, Burnett J, et al. Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex. Mol Ther. 2016;24:488-98 pubmed 出版商
Zhang Y, Yin C, Zhang T, Li F, Yang W, Kaminski R, et al. CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs. Sci Rep. 2015;5:16277 pubmed 出版商
Konermann S, Brigham M, Trevino A, Joung J, Abudayyeh O, Bárcena C, et al. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 2015;517:583-8 pubmed 出版商
目录号 :
产品名称 :
lenti MS2-P65-HSF1_Hygro
文章 :
细菌的抗性 :
克隆 :
Mammalian Expression
生长记录 :
IMPORTANT NOTES: SAM libraries ordered prior to 4/3/2017 were shipped with this plasmid included. As of 4/3/2017, a version of this plasmid with improved titer is available: Addgene plasmids #89308 lentiMPH v2 ( http://addgene.org/89308 ) For additional information, protocols and an activator sgRNA design tool, visit the Zhang lab website: http://sam.genome-engineering.org/
生长株 :
lenti vector encoding the MS2-P65-HSF1 activator helper complex with a 2A Hygro resistance marker NOTE: A version of this plasmid with improved titer is available: Addgene plasmid #89308 lentiMPH v2
起源 :
主要研究者 :
clone_methodRestriction Enzyme
mutationN55K in MS2
Homo sapiens
抗性标记物 :
标签 :
High Copy
条款 :
更多信息或购买 :
490 Arsenal Way, Suite 100
Watertown, MA 02472
公司总部: 美国