抗体

Anti-TRPC3-ATTO Fluor-594 Antibody

ACC-016-AR

1 X 50 mcl

735美元

多克隆

domestic rabbit

ATTO 594

人类, 小鼠, 大鼠

免疫组化, 免疫细胞化学

ACC-016-AR

Primary Antibody>Intracellular>Labeled

Insert

Anti-TRPC3-ATTO Fluor-594 Antibody

Anti-TRPC3 Antibody (#ACC-016) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot, immunoprecipitation, immunohistochemistry, immunocytochemistry, and indirect flow cytometry applications. It has been designed to recognize TRPC3 from mouse, rat, and human samples. nAnti-TRPC3-ATTO Fluor-594 Antibody (#ACC-016-AR) is directly labeled with ATTO-594 fluorescent dye. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-594 fluorescent label belongs to the class of Rhodamine dyes and can be used with fluorescent equipment typically optimized to detect Texas Red and Alexa-594. Anti-TRPC3-ATTO Fluor-594 Antibody can be used in immunohistochemistry applications and is specially suited to experiments requiring simultaneous labeling of different markers.

A Rabbit Polyclonal Antibody to TRPC3 Channel Conjugated to the Fluorescent Dye ATTO-594

BLP-CC016

TRPC3, Short transient receptor potential channel 3, Transient receptor protein 3, TRP3

TRPC3 Channel

Ion Channels > TRP Channels > TRPC Channels > Antibodies to TRPC Channels

ATTO 594 (Red)

IF, 免疫组化

兔

多克隆

兔IgG

TRPC3

人类(试验);小鼠(试验);大鼠(试验)

Human, rat - 13/14 amino acid residues identical.

The Transient Receptor Potential (TRP) superfamily is one of the largest ion channel family and consists of diverse groups of proteins. In mammals about 28 genes encode the TRP ion channel subunits. The mammalian TRP superfamily comprises six subfamilies known as the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipins), TRPP (polycystin) and the TRPA (ANKTM1) ion channels.1-4 The TRPC subfamily consists of seven proteins named TRPC1 to 7 which can be further divided into four subgroups based on their sequence homology and functional similarities: TRPC1; TRPC4 and TRPC5; TRPC3, TRPC6, TRPC7 and TRPC2.2,5 They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues. TRPC3, TRPC6 and TRPC7 form non-selective cationic channels that are activated by the stimulation of GPCRs. TRPC3 was shown to be activated by DAG and SOC, in heterologous expression systems.6,7

合成肽

intracellular

Intracellular, C-terminus

HKLSEKLNPSVLRC, corresponding to amino acid residues 822-835 of mouse TRPC3

Peptide HKLSEKLNPSVLRC, corresponding to amino acid residues 822-835 of mouse TRPC3 (Accession Q9QZC1). Intracellular, C-terminus.

1 X 50 mcl

1毫克/毫升

1毫克/毫升

磷酸盐缓冲液(PBS)

pH值7.4

1% BSA, 0.05% NaN3 (% of reconstituted antibody)

Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

冻干粉末

Affinity purified on immobilized antigen

-20°C

Q9QZC1

AGP-002

Reconstitution: 1 X 50 mcl double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C, as long as it is in its original form, it can last a minimum of 3 years this way. The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

1

50

mcl

735美元