产品简要
公司名称 :
Alomone Labs
产品类型 :
抗体
产品名称 :
抗瞬时受体电位香草酸亚型1(VR1)抗体
目录 :
ACC-030
规格 :
1 X 25 mcl
价格 :
425美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 93
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; pigs ; 1:200; 图 2b
Toschi A, Galiazzo G, Piva A, Tagliavia C, Mazzuoli Weber G, Chiocchetti R, et al. Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum. Animals (Basel). 2021;11: pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 s2a
  • 免疫印迹; 小鼠; 1:1000; 图 3a
Liu B, Cao Q, Zhao X, Liu H, Zhang Y. Inhibition of TRPV1 by SHP-1 in nociceptive primary sensory neurons is critical in PD-L1 analgesia. JCI Insight. 2020;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4e
Trevisan A, Bauer M, Brindley R, Currie K, Carter B. Jedi-1 deficiency increases sensory neuron excitability through a non-cell autonomous mechanism. Sci Rep. 2020;10:1300 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s1a
Cohen J, Edwards T, Liu A, Hirai T, Jones M, Wu J, et al. Cutaneous TRPV1+ Neurons Trigger Protective Innate Type 17 Anticipatory Immunity. Cell. 2019;178:919-932.e14 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 4b
Huang T, Lin S, Malewicz N, Zhang Y, Zhang Y, Goulding M, et al. Identifying the pathways required for coping behaviours associated with sustained pain. Nature. 2019;565:86-90 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3b
Alshawaf A, Viventi S, Qiu W, D Abaco G, Nayagam B, Erlichster M, et al. Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. Sci Rep. 2018;8:603 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 4c
  • 免疫印迹; 大鼠; 1:200; 图 4b
Hu Y, Mi X, Huang C, Wang H, Song J, Shu Q, et al. Multiple H+ sensors mediate the extracellular acidification-induced [Ca2+]i elevation in cultured rat ventricular cardiomyocytes. Sci Rep. 2017;7:44951 pubmed 出版商
Omari S, Geraghty D, Khalafallah A, Venkat P, Shegog Y, Ragg S, et al. Optimized flow cytometric detection of transient receptor potential vanilloid-1 (TRPV1) in human hematological malignancies. Med Oncol. 2022;39:81 pubmed 出版商
Chakraborty R, Acharya T, Tiwari N, Majhi R, Kumar S, Goswami L, et al. Hydrogel-Mediated Release of TRPV1 Modulators to Fine Tune Osteoclastogenesis. ACS Omega. 2022;7:9537-9550 pubmed 出版商
Hsiao I, Lin Y. Electroacupuncture Reduces Fibromyalgia Pain by Attenuating the HMGB1, S100B, and TRPV1 Signalling Pathways in the Mouse Brain. Evid Based Complement Alternat Med. 2022;2022:2242074 pubmed 出版商
Becker J, Papagianni A, Herrmann E, N xf6 ller F, Sommer C, Rittner H. Transient hypoalgesia after COVID-19 infection. Pain Rep. 2022;7:e990 pubmed 出版商
Belinskaia M, Zurawski T, Kaza S, Antoniazzi C, Dolly J, Lawrence G. NGF Enhances CGRP Release Evoked by Capsaicin from Rat Trigeminal Neurons: Differential Inhibition by SNAP-25-Cleaving Proteases. Int J Mol Sci. 2022;23: pubmed 出版商
Li L, Ma L, Luo Z, Wei X, Zhao Y, Zhou C, et al. Lack of TRPV1 aggravates obesity-associated hypertension through the disturbance of mitochondrial Ca2+ homeostasis in brown adipose tissue. Hypertens Res. 2022;45:789-801 pubmed 出版商
Hornung R, Raut N, Cantu D, Lockhart L, Averitt D. Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone. Mol Pain. 2022;18:17448069211069255 pubmed 出版商
Grelet S, Fr xe9 reux C, Obellianne C, Noguchi K, Howley B, Dalton A, et al. TGFβ-induced expression of long noncoding lincRNA Platr18 controls breast cancer axonogenesis. Life Sci Alliance. 2022;5: pubmed 出版商
Karpinski B, Maynard T, Bryan C, Yitsege G, Horvath A, Lee N, et al. Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome. Dis Model Mech. 2022;15: pubmed 出版商
Barr J, Kruse A, Restaino A, Tulina N, Stuckelberger S, Vermeer S, et al. Intra-Tumoral Nerve-Tracing in a Novel Syngeneic Model of High-Grade Serous Ovarian Carcinoma. Cells. 2021;10: pubmed 出版商
Nakazawa Y, Petrova R, Sugiyama Y, Nagai N, Tamura H, Donaldson P. Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens. Int J Mol Sci. 2021;22: pubmed 出版商
Li J, Chen Y, Liu J, Zhang D, Liang P, Lu P, et al. Elevated Expression and Activity of Sodium Leak Channel Contributes to Neuronal Sensitization of Inflammatory Pain in Rats. Front Mol Neurosci. 2021;14:723395 pubmed 出版商
Zhang Y, Ma S, Ke X, Yi Y, Yu H, Yu D, et al. The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons. Cell Biosci. 2021;11:167 pubmed 出版商
Giuliano C, Francavilla M, Ongari G, Petese A, Ghezzi C, Rossini N, et al. Neuroprotective and Symptomatic Effects of Cannabidiol in an Animal Model of Parkinson's Disease. Int J Mol Sci. 2021;22: pubmed 出版商
Wang W, Kong M, Dou Y, Xue S, Liu Y, Zhang Y, et al. Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release. Int J Mol Sci. 2021;22: pubmed 出版商
Sattler K, El Battrawy I, Cyganek L, Lang S, Lan H, Li X, et al. TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes. Sci Rep. 2021;11:14689 pubmed 出版商
Xue C, Liu S, Hu J, Huang J, Liu H, Qiu Z, et al. Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway. Chin Med. 2021;16:58 pubmed 出版商
Jiao H, Ivanusic J, McMenamin P, Chinnery H. Distribution of Corneal TRPV1 and Its Association With Immune Cells During Homeostasis and Injury. Invest Ophthalmol Vis Sci. 2021;62:6 pubmed 出版商
Makhmutova M, Caicedo A. Optical Imaging of Pancreatic Innervation. Front Endocrinol (Lausanne). 2021;12:663022 pubmed 出版商
Pascual Go xf1 i E, Fehmi J, Lleix xe0 C, Mart xed n Aguilar L, Devaux J, H xf6 ftberger R, et al. Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyradiculoneuropathy. Brain. 2021;144:1183-1196 pubmed 出版商
Landy M, Goyal M, Casey K, Liu C, Lai H. Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation. Cell Rep. 2021;34:108913 pubmed 出版商
Zhang Y, Li C, Qin Y, Cepparulo P, Millman M, Chopp M, et al. Small extracellular vesicles ameliorate peripheral neuropathy and enhance chemotherapy of oxaliplatin on ovarian cancer. J Extracell Vesicles. 2021;10:e12073 pubmed 出版商
Nakazawa Y, Doki Y, Sugiyama Y, Kobayashi R, Nagai N, Morisita N, et al. Effect of Alpha-Glucosyl-Hesperidin Consumption on Lens Sclerosis and Presbyopia. Cells. 2021;10: pubmed 出版商
Xie M, Cao X, Zeng W, Lai R, Guo L, Wang J, et al. ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking. Nat Commun. 2021;12:1401 pubmed 出版商
Morgan M, Thai J, Trinh P, Habib M, Effendi K, Ivanusic J. ASIC3 inhibition modulates inflammation-induced changes in the activity and sensitivity of Aδ and C fiber sensory neurons that innervate bone. Mol Pain. 2020;16:1744806920975950 pubmed 出版商
Ando M, Hayashi Y, Hitomi S, Shibuta I, Furukawa A, Oto T, et al. Oxytocin-Dependent Regulation of TRPs Expression in Trigeminal Ganglion Neurons Attenuates Orofacial Neuropathic Pain Following Infraorbital Nerve Injury in Rats. Int J Mol Sci. 2020;21: pubmed 出版商
Duo L, Wu T, Ke Z, Hu L, Wang C, Teng G, et al. Gain of Function of Ion Channel TRPV1 Exacerbates Experimental Colitis by Promoting Dendritic Cell Activation. Mol Ther Nucleic Acids. 2020;22:924-936 pubmed 出版商
Leo M, Schmitt L, K xfc sterarent P, Kutritz A, Rassaf T, Kleinschnitz C, et al. Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons. Int J Mol Sci. 2020;21: pubmed 出版商
Wang Y, Mo X, Ping C, Huang Q, Zhang H, Xie C, et al. Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit. J Biol Chem. 2020;295:17337-17348 pubmed 出版商
Lin Y, Chou A, Su H, Su K. Transient receptor potential V1 (TRPV1) modulates the therapeutic effects for comorbidity of pain and depression: The common molecular implication for electroacupuncture and omega-3 polyunsaturated fatty acids. Brain Behav Immun. 2020;89:604-614 pubmed 出版商
Otto M, Bucher C, Liu W, Muller M, Schmidt T, Kardell M, et al. 12(S)-HETE mediates diabetes-induced endothelial dysfunction by activating intracellular endothelial cell TRPV1. J Clin Invest. 2020;130:4999-5010 pubmed 出版商
Mailhot B, Christin M, Tessandier N, Sotoudeh C, Bretheau F, Turmel R, et al. Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases. J Exp Med. 2020;217: pubmed 出版商
Meleine M, Mounien L, Atmani K, Ouelaa W, B xf4 le Feysot C, Gu xe9 rin C, et al. Ghrelin inhibits autonomic response to gastric distension in rats by acting on vagal pathway. Sci Rep. 2020;10:9986 pubmed 出版商
Schoepf C, Zeidler M, Spiecker L, Kern G, Lechner J, Kummer K, et al. Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors. Brain Sci. 2020;10: pubmed 出版商
Han G, Chay D, Nam S, Cho H, Chung J, Kim J. Prognostic Significance of Transient Receptor Potential Vanilloid Type 1 (TRPV1) and Phosphatase and Tension Homolog (PTEN) in Epithelial Ovarian Cancer. Cancer Genomics Proteomics. 2020;17:309-319 pubmed 出版商
Zhang B, Zhang Y, Sun Q, Zhang P, Wang X, Xu G, et al. Alpha-lipoic acid downregulates TRPV1 receptor via NF-κB and attenuates neuropathic pain in rats with diabetes. CNS Neurosci Ther. 2020;26:762-772 pubmed 出版商
Inprasit C, Huang Y, Lin Y. Evidence for acupoint catgut embedding treatment and TRPV1 gene deletion increasing weight control in murine model. Int J Mol Med. 2020;45:779-792 pubmed 出版商
Liao C, Li J, Hsieh C. Auricular Electrical Stimulation Alleviates Headache through CGRP/COX-2/TRPV1/TRPA1 Signaling Pathways in a Nitroglycerin-Induced Migraine Rat Model. Evid Based Complement Alternat Med. 2019;2019:2413919 pubmed 出版商
Li Y, Yin C, Li X, Liu B, Wang J, Zheng X, et al. Electroacupuncture Alleviates Paclitaxel-Induced Peripheral Neuropathic Pain in Rats via Suppressing TLR4 Signaling and TRPV1 Upregulation in Sensory Neurons. Int J Mol Sci. 2019;20: pubmed 出版商
Chiocchetti R, Galiazzo G, Tagliavia C, Stanzani A, Giancola F, Menchetti M, et al. Cellular Distribution of Canonical and Putative Cannabinoid Receptors in Canine Cervical Dorsal Root Ganglia. Front Vet Sci. 2019;6:313 pubmed 出版商
Yap J, Tai Y, Fröhlich J, Fong C, Yin J, Foo Z, et al. Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism. FASEB J. 2019;33:12853-12872 pubmed 出版商
Yen C, Wu T, Hsieh C, Huang Y, Lin Y. Distal Electroacupuncture at the LI4 Acupoint Reduces CFA-Induced Inflammatory Pain via the Brain TRPV1 Signaling Pathway. Int J Mol Sci. 2019;20: pubmed 出版商
Recla J, Bubier J, Gatti D, Ryan J, Long K, Robledo R, et al. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. 2019;160:1740-1753 pubmed 出版商
Jiang M, Li H, Johnson A, Karasawa T, Zhang Y, Meier W, et al. Inflammation up-regulates cochlear expression of TRPV1 to potentiate drug-induced hearing loss. Sci Adv. 2019;5:eaaw1836 pubmed 出版商
Nakazawa Y, Donaldson P, Petrova R. Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lens. Exp Eye Res. 2019;:107707 pubmed 出版商
Li M, Zhang C, Zong Y, Feng J, Ma T, Hu M, et al. Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK. Cell Metab. 2019;: pubmed 出版商
BARTSCH V, Niehaus J, Taylor Blake B, Zylka M. Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice. PLoS ONE. 2019;14:e0217819 pubmed 出版商
Kim K, Baek J, Jeong J, Nam J, Park E, Bok E, et al. Delayed Treatment of Capsaicin Produces Partial Motor Recovery by Enhancing Dopamine Function in MPP+-lesioned Rats via Ciliary Neurotrophic Factor. Exp Neurobiol. 2019;28:289-299 pubmed 出版商
Ong J, Kinsman B, Sved A, Rush B, Tan R, Carattino M, et al. Renal sensory nerves increase sympathetic nerve activity and blood pressure in 2-kidney 1-clip hypertensive mice. J Neurophysiol. 2019;122:358-367 pubmed 出版商
Yang Y, Wang S, Kobayashi K, Hao Y, Kanda H, Kondo T, et al. TRPA1-expressing lamina propria mesenchymal cells regulate colonic motility. JCI Insight. 2019;4: pubmed 出版商
Lucido C, Wynja E, Madeo M, Williamson C, Schwartz L, Imblum B, et al. Innervation of cervical carcinoma is mediated by cancer-derived exosomes. Gynecol Oncol. 2019;154:228-235 pubmed 出版商
Morgan M, Nencini S, Thai J, Ivanusic J. TRPV1 activation alters the function of Aδ and C fiber sensory neurons that innervate bone. Bone. 2019;123:168-175 pubmed 出版商
Liu B, Qiu M, Zong P, Chen X, Zhao K, Li Y, et al. Distribution, Morphological Characterization, and Resiniferatoxin-Susceptibility of Sensory Neurons That Innervate Rat Perirenal Adipose Tissue. Front Neuroanat. 2019;13:29 pubmed 出版商
Guo S, Lin J, Huang L, Yang Y, Chen C, Li N, et al. Silencing of spinal Trpv1 attenuates neuropathic pain in rats by inhibiting CAMKII expression and ERK2 phosphorylation. Sci Rep. 2019;9:2769 pubmed 出版商
Huang R, Wang F, Yang Y, Ma W, Lin Z, Cheng N, et al. Recurrent activations of transient receptor potential vanilloid-1 and vanilloid-4 promote cellular proliferation and migration in esophageal squamous cell carcinoma cells. FEBS Open Bio. 2019;9:206-225 pubmed 出版商
Meents J, Bressan E, Sontag S, Foerster A, Hautvast P, R xf6 sseler C, et al. The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients. Pain. 2019;160:1327-1341 pubmed 出版商
Noseda R, Melo Carrillo A, Nir R, Strassman A, Burstein R. Non-Trigeminal Nociceptive Innervation of the Posterior Dura: Implications to Occipital Headache. J Neurosci. 2019;39:1867-1880 pubmed 出版商
Hossain M, Ando H, Unno S, Masuda Y, Kitagawa J. Activation of TRPV1 and TRPM8 Channels in the Larynx and Associated Laryngopharyngeal Regions Facilitates the Swallowing Reflex. Int J Mol Sci. 2018;19: pubmed 出版商
Türker E, Garreis F, Khajavi N, Reinach P, Joshi P, Brockmann T, et al. Vascular Endothelial Growth Factor (VEGF) Induced Downstream Responses to Transient Receptor Potential Vanilloid 1 (TRPV1) and 3-Iodothyronamine (3-T1AM) in Human Corneal Keratocytes. Front Endocrinol (Lausanne). 2018;9:670 pubmed 出版商
Bou Karam J, Cai W, Mohamed R, Huang T, Meng L, HOMAN E, et al. TRPV1 neurons regulate β-cell function in a sex-dependent manner. Mol Metab. 2018;18:60-67 pubmed 出版商
Zhang W, Drzymalski D, Sun L, Xu Q, Jiao C, Wang L, et al. Involvement of mGluR5 and TRPV1 in visceral nociception in a rat model of uterine cervical distension. Mol Pain. 2018;14:1744806918816850 pubmed 出版商
Baek J, Jeong J, Kim K, Won S, Chung Y, Nam J, et al. Inhibition of Microglia-Derived Oxidative Stress by Ciliary Neurotrophic Factor Protects Dopamine Neurons In Vivo from MPP⁺ Neurotoxicity. Int J Mol Sci. 2018;19: pubmed 出版商
Madeo M, Colbert P, Vermeer D, Lucido C, Cain J, Vichaya E, et al. Cancer exosomes induce tumor innervation. Nat Commun. 2018;9:4284 pubmed 出版商
Jeong J, Lee D, Liu S, Chua S, Schwartz G, Jo Y. Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake. PLoS Biol. 2018;16:e2004399 pubmed 出版商
Wang Y, Gao Y, Tian Q, Deng Q, Wang Y, Zhou T, et al. TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain. Nat Commun. 2018;9:1529 pubmed 出版商
Alamri A, Wood R, Ivanusic J, Brock J. The neurochemistry and morphology of functionally identified corneal polymodal nociceptors and cold thermoreceptors. PLoS ONE. 2018;13:e0195108 pubmed 出版商
Yang J, Hsieh C, Lin Y. Role of Transient Receptor Potential Vanilloid 1 in Electroacupuncture Analgesia on Chronic Inflammatory Pain in Mice. Biomed Res Int. 2017;2017:5068347 pubmed 出版商
Ortíz Rentería M, Juárez Contreras R, González Ramírez R, Islas L, Sierra Ramírez F, Llorente I, et al. TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain. Proc Natl Acad Sci U S A. 2018;115:E1657-E1666 pubmed 出版商
Nie J, Liu X. Quercetin alleviates generalized hyperalgesia in mice with induced adenomyosis. Mol Med Rep. 2017;16:5370-5376 pubmed 出版商
Lu P, Hudgins R, Liu X, Ford Z, Hofmann M, Queme L, et al. Upregulation of P2Y1 in neonatal nociceptors regulates heat and mechanical sensitization during cutaneous inflammation. Mol Pain. 2017;13:1744806917730255 pubmed 出版商
Leo M, Schulte M, Schmitt L, Sch xe4 fers M, Kleinschnitz C, Hagenacker T. Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior. Mediators Inflamm. 2017;2017:2786427 pubmed 出版商
Li G, Zou X, Kuang G, Ren Y, Deng C, Lin Q, et al. Preventative effects of fermented Chimonobambusa quadrangularis shoot on activated carbon-induced constipation. Exp Ther Med. 2017;13:1093-1100 pubmed 出版商
Nencini S, Ringuet M, Kim D, Chen Y, Greenhill C, Ivanusic J. Mechanisms of nerve growth factor signaling in bone nociceptors and in an animal model of inflammatory bone pain. Mol Pain. 2017;13:1744806917697011 pubmed 出版商
Zinn S, Sisignano M, Kern K, Pierre S, Tunaru S, Jordan H, et al. The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons. J Biol Chem. 2017;292:6123-6134 pubmed 出版商
Liu C, Su H, Wan H, Qin Q, Wu X, Kong X, et al. Forsythoside A exerts antipyretic effect on yeast-induced pyrexia mice via inhibiting transient receptor potential vanilloid 1 function. Int J Biol Sci. 2017;13:65-75 pubmed 出版商
De Toni L, Garolla A, Menegazzo M, Magagna S, Di Nisio A, Šabović I, et al. Heat Sensing Receptor TRPV1 Is a Mediator of Thermotaxis in Human Spermatozoa. PLoS ONE. 2016;11:e0167622 pubmed 出版商
Obi S, Nakajima T, Hasegawa T, Kikuchi H, Oguri G, Takahashi M, et al. Heat induces interleukin-6 in skeletal muscle cells via TRPV1/PKC/CREB pathways. J Appl Physiol (1985). 2017;122:683-694 pubmed 出版商
Yadav M, Goswami C. TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes. Channels (Austin). 2017;11:196-208 pubmed 出版商
Khoutorsky A, Sorge R, Prager Khoutorsky M, Pawlowski S, Longo G, Jafarnejad S, et al. eIF2? phosphorylation controls thermal nociception. Proc Natl Acad Sci U S A. 2016;113:11949-11954 pubmed
Doppler K, Appeltshauser L, Villmann C, Martin C, Peles E, Krämer H, et al. Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy. Brain. 2016;139:2617-2630 pubmed
Xiao Y, Chen X, Zhang P, Xu Q, Zheng H, Xu G. TRPV1-mediated presynaptic transmission in basolateral amygdala contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation. Sci Rep. 2016;6:29026 pubmed 出版商
Hiyama T, Utsunomiya A, Matsumoto M, Fujikawa A, Lin C, Hara K, et al. Adipsic hypernatremia without hypothalamic lesions accompanied by autoantibodies to subfornical organ. Brain Pathol. 2017;27:323-331 pubmed 出版商
Tanaka Y, Niwa S, Dong M, Farkhondeh A, Wang L, Zhou R, et al. The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function. Neuron. 2016;90:1215-1229 pubmed 出版商
Martínez N, Abán C, Leguizamón G, Damiano A, Farina M. TPRV-1 expression in human preeclamptic placenta. Placenta. 2016;40:25-8 pubmed 出版商
Bertin S, Aoki Nonaka Y, de Jong P, Nohara L, Xu H, Stanwood S, et al. The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4? T cells. Nat Immunol. 2014;15:1055-1063 pubmed 出版商
Sterle I, Zupancic D, Romih R. Correlation between urothelial differentiation and sensory proteins P2X3, P2X5, TRPV1, and TRPV4 in normal urothelium and papillary carcinoma of human bladder. Biomed Res Int. 2014;2014:805236 pubmed 出版商
图像
图像 1 :
Alomone Labs ACC-030 图像 1
Western blot analysis of human TRPV1 transfected HEK-293 cells: - 1. Anti-TRPV1 (VR1) Antibody (#ACC-030), (1:200).2. Anti-TRPV1 (VR1) Antibody, preincubated with TRPV1/VR1 Blocking Peptide (#BLP-CC030).
图像 2 :
Alomone Labs ACC-030 图像 2
Expression of TRPV1 in rat DRG - Immunohistochemical staining of rat dorsal root ganglion (DRG) using Anti-TRPV1 (VR1) Antibody (#ACC-030). A. TRPV1 (red) in DRG neurons. B. Staining with mouse anti-Parvalbumin (green) in the same DRG section. C. Confocal merge of TRPV1 and Parvalbumin demonstrates colocalization (arrows).
图像 3 :
Alomone Labs ACC-030 图像 3
Western blot analysis of rat DRG lysate: - 1.Anti-TRPV1 (VR1) Antibody (#ACC-030) (1:200).2. Anti-TRPV1 (VR1) Antibody preincubated with the negative control antigen.
产品信息
SKU号 :
ACC-030_1_25_mcl
ParentSKU :
ACC-030
Taxonomy Node :
Primary Antibody>Intracellular>Non-Labeled
Action :
Insert
产品名称 :
抗瞬时受体电位香草酸亚型1(VR1)抗体
产品描述 :
Anti-TRPV1 (VR1) Antibody (#ACC-030) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize TRPV1 from mouse, rat, and human samples.
Short Description :
A Rabbit Polyclonal Antibody to TRPV1 (VR1) Channel
Negative Control :
BLP-CC030
同义词 :
TRPV1 (VR1), Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Vanilloid receptor 1, OTRPC1
靶标名 :
TRPV1 (VR1) Channel
Primary Category (Old) :
Ion Channels > TRP Channels > TRPV Channels > Antibodies to TRPV Channels
标记/共轭标签 :
未共轭
应用 :
免疫细胞化学, IF, IFC, 免疫组化, 免疫印迹
宿主 :
克隆性 :
多克隆
抗体亚型 :
兔IgG
基因符号 :
瞬时受体电位香草酸亚型1
反应物种 :
人类(试验);小鼠(试验);大鼠(试验)
同源 :
Mouse, guinea pig - 14/15 amino acid residues identical; human - 10/15 amino acid residues identical.
靶标/背景信息 :
TRPV1 (also named VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members named, TRPV1-6. The TRPV1 channel is a vanilloid gated, nonselective cation channel. The channel has sequence homology to the TRP family, and shares a similar predicted structure of six transmembrane domain (TM) with a pore loop between TM5 and TM6.1 TRPV1 is expressed predominantly in nociceptors and in sensory neurons.2,3 TRPV1 has many activators among them heat, protons, vanilloids like capsaicin, resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation.5,6 Other members of this family, TRPV2, TRPV3 and TRPV4 also show thermal sensitivity.7 Conformational changes in the C-terminus are responsible for many functions such as permeation and gating. There is also evidence that deletion of the C-terminus causes a loss of sensitivity to any stimuli.7 Recent studies demonstrated involvement of TRPV1 in apoptosis where inhibition of the receptor prevented apoptosis.8,9
免疫原 :
合成肽
区域 :
intracellular
Loop :
Intracellular, C-terminus
序列 :
(C)EDAEVFKDSMVPGEK, corresponding to amino acid residues 824-838 of rat TRPV1
序列文本 :
Peptide (C)EDAEVFKDSMVPGEK, corresponding to amino acid residues 824-838 of rat TRPV1 (Accession O35433). Intracellular, C-terminus.
Primary Size (Size+Units) :
1 X 25 mcl
浓度 :
0.8毫克/毫升
浓度 :
08毫克/毫升
缓冲液 :
磷酸盐缓冲液(PBS)
pH值 :
pH值7.4
防腐剂 :
1% BSA, 0.05% NaN3 (% of reconstituted antibody)
Additive(s) :
Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
格式(液体/冻干) :
冻干粉末
纯化来源(杂交瘤细胞, 腹水 :
Affinity purified on immobilized antigen
储存温度 :
-20°C
UniProt数据库 :
O35433
Top Related :
ACC-037, ACC-034, ASC-016, AGP-118, ACC-049
储存和重组 :
Reconstitution: 1 X 25 mcl double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C, as long as it is in its original form, it can last a minimum of 3 years this way. The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 × g 5 min).
包装规格 :
1
产品规格/规格 :
25
单位 :
mcl
标价美国[美元] :
425美元
ICC Legend :
Expression of TRPV1 in rat DRG primary culture - Immunocytochemical staining of paraformaldehyde-fixed and permeabilized rat dorsal root ganglia (DRG) primary cells with Anti-TRPV1 (VR1) Antibody (#ACC-030), (1:200). A. Staining followed by goat anti-rabbit-AlexaFluor-555 secondary antibody. B. Nuclear staining using the cell-permeable dye Hoechst 33342. C. Merged image of panels A and B.
更多信息或购买 :
公司信息
Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com
972-2-587-2202
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Alomone Labs公司成立于1989年,在离子通道、GPCR及神经信号通路研究等领域占据全球领先地位。